Best TWAS P=1.45e-09 · Best GWAS P=7.57e-11 conditioned to 0.0217
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | ZNHIT6 | 0.05 | 0.01 | bslmm | 552 | 0.01 | 1.9e-02 | 4.5 | -5.5 | 3.3e-08 | -0.04 | 0.12 | 0.50 | TRUE |
2 | GTEx | Adrenal Gland | DDAH1 | 0.26 | 0.21 | lasso | 6 | 0.20 | 8.7e-08 | 4.1 | -5.3 | 1.1e-07 | -0.05 | 0.17 | 0.81 | FALSE |
3 | YFS | Blood | BCL10 | 0.24 | 0.12 | enet | 48 | 0.19 | 1.1e-59 | 3.7 | 5.1 | 2.9e-07 | -0.03 | 0.91 | 0.06 | TRUE |
4 | YFS | Blood | ODF2L | 0.04 | 0.04 | enet | 18 | 0.04 | 1.8e-12 | 6.4 | -6.0 | 1.4e-09 | -0.91 | 0.00 | 1.00 | TRUE |