TWAS
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Models
Genes
Traits
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Traits
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Whole body fat-free mass
:
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chr8:115,726,164-117,375,332
Best TWAS P=1.28e-13 · Best GWAS P=1.8e-17 conditioned to 6.73e-06
115.8M
116M
116.2M
116.4M
116.6M
116.8M
117M
117.2M
117.4M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Brain Lower Grade Glioma
TRPS1
0.04
0.03
blup
102
0.01
0.0096
6.8
-7.4
1.3e-13
-0.42
0.08
0.06
TRUE
1
CommonMind
Brain Pre-frontal Cortex
TRPS1
0.05
0.02
enet
19
0.02
0.0024
8.5
-6.2
4.6e-10
-0.74
0.00
0.99
TRUE