[Hub]/) : Traits : Whole body fat-free mass :

chr8:119,737,284-121,760,704

Best TWAS P=4.52e-15 · Best GWAS P=2.63e-16 conditioned to 0.228

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NOV 0.06 0.02 enet 8 0.05 1.5e-06 -4.2 -5.8 7.2e-09 0.71 0.22 0.78 FALSE
2 GTEx Adrenal Gland DEPTOR 0.16 -0.01 enet 24 0.00 3.7e-01 -2.8 5.1 2.8e-07 -0.08 0.10 0.06 TRUE
3 GTEx Artery Aorta NOV 0.12 0.05 enet 18 0.04 3.7e-03 -5.6 -6.9 4.6e-12 0.79 0.03 0.85 FALSE
4 GTEx Cells Transformed fibroblasts NOV 0.10 0.04 enet 30 0.03 3.7e-03 -7.7 -5.5 4.5e-08 0.56 0.12 0.79 FALSE
5 GTEx Colon Sigmoid NOV 0.15 0.16 lasso 4 0.15 6.6e-06 -7.8 -7.7 1.3e-14 0.91 0.03 0.95 FALSE
6 GTEx Lung NOV 0.06 0.02 enet 23 0.03 2.5e-03 -3.7 -6.3 2.1e-10 0.66 0.20 0.46 FALSE
7 GTEx Nerve Tibial TAF2 0.14 0.04 enet 10 0.07 1.5e-05 4.5 -5.9 4.1e-09 0.19 0.89 0.04 FALSE
8 GTEx Skin Sun Exposed Lower leg NOV 0.11 0.03 lasso 7 0.04 1.4e-04 -7.6 -6.8 7.9e-12 0.95 0.01 0.99 FALSE
9 NTR Blood NOV 0.02 0.01 bslmm 481 0.01 1.7e-04 -7.7 -6.4 1.6e-10 0.78 0.02 0.98 FALSE
10 YFS Blood ENPP2 0.03 0.02 enet 8 0.03 7.6e-09 -4.4 -5.7 1.6e-08 0.10 1.00 0.00 TRUE
11 The Cancer Genome Atlas Bladder Urothelial Carcinoma NOV 0.03 0.00 blup 42 0.01 5.3e-02 -7.6 -7.8 7.9e-15 0.97 0.02 0.77 FALSE
12 The Cancer Genome Atlas Colon Adenocarcinoma NOV 0.31 0.10 blup 42 0.10 1.2e-06 -8.2 -6.7 1.7e-11 0.83 0.01 0.99 FALSE
13 The Cancer Genome Atlas Pancreatic Adenocarcinoma NOV 0.11 0.02 enet 15 0.05 2.9e-03 -8.2 -7.8 4.5e-15 0.84 0.01 0.64 TRUE
14 The Cancer Genome Atlas Prostate Adenocarcinoma NOV 0.04 0.05 blup 42 0.05 8.7e-06 -7.7 -6.7 1.8e-11 0.82 0.05 0.95 FALSE