[Hub]/) : Traits : Whole body fat-free mass : ← →

chr9:138,628,816-140,321,666

Best TWAS P=7e-12 · Best GWAS P=3.61e-08 conditioned to 0.842

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Brain Caudate basal ganglia	INPP5E	0.23	0.20	enet	8	0.22	7.2e-07	5.2	-5.1	2.6e-07	-0.89	0.04	0.93	FALSE
2	GTEx	Brain Caudate basal ganglia	SNHG7	0.37	0.10	lasso	6	0.27	2.5e-08	-3.7	6.9	7.0e-12	0.52	0.03	0.81	TRUE
3	GTEx	Brain Cerebellar Hemisphere	INPP5E	0.25	0.23	enet	6	0.17	3.4e-05	5.1	-5.3	9.2e-08	-0.90	0.03	0.96	FALSE
4	GTEx	Brain Cerebellum	INPP5E	0.40	0.30	enet	20	0.29	3.6e-09	5.2	-5.2	1.6e-07	-0.90	0.03	0.97	FALSE
5	GTEx	Esophagus Mucosa	INPP5E	0.11	0.12	lasso	3	0.12	1.0e-08	5.1	-5.1	2.7e-07	-0.93	0.04	0.96	FALSE
6	GTEx	Heart Atrial Appendage	INPP5E	0.13	0.12	lasso	2	0.10	3.5e-05	5.1	-5.1	3.0e-07	-0.90	0.03	0.91	FALSE
7	GTEx	Nerve Tibial	INPP5E	0.13	0.17	enet	10	0.14	3.7e-10	5.1	-5.3	1.1e-07	-0.91	0.04	0.96	FALSE
8	GTEx	Ovary	INPP5E	0.24	0.13	enet	11	0.15	1.9e-04	4.7	-6.1	8.4e-10	-0.90	0.02	0.84	FALSE
9	GTEx	Ovary	SEC16A	0.33	0.06	enet	10	0.14	3.4e-04	4.5	-6.1	1.4e-09	-0.65	0.05	0.27	TRUE
10	GTEx	Stomach	SEC16A	0.15	0.09	lasso	4	0.10	1.8e-05	5.3	-5.2	2.1e-07	-0.88	0.02	0.98	FALSE
11	GTEx	Uterus	INPP5E	0.60	0.04	enet	10	0.22	3.4e-05	5.5	-5.5	4.0e-08	-0.84	0.03	0.70	FALSE
12	GTEx	Whole Blood	SEC16A	0.07	0.05	lasso	5	0.04	1.3e-04	5.1	-5.7	1.1e-08	-0.91	0.02	0.98	FALSE
13	YFS	Blood	INPP5E	0.33	0.55	lasso	6	0.57	2.9e-235	5.5	-5.5	4.7e-08	-0.98	0.01	0.99	FALSE
14	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	INPP5E	0.25	0.10	lasso	3	0.09	4.9e-05	5.5	-5.7	1.3e-08	-1.00	0.00	0.98	FALSE
15	The Cancer Genome Atlas	Colon Adenocarcinoma	INPP5E	0.11	0.08	lasso	2	0.08	3.4e-05	5.5	-5.5	4.0e-08	-1.00	0.00	0.96	FALSE
16	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	INPP5E	0.07	0.04	blup	54	0.07	6.0e-05	5.5	-5.7	1.0e-08	-0.91	0.01	0.96	FALSE
17	The Cancer Genome Atlas	Prostate Adenocarcinoma	SEC16A	0.08	0.10	lasso	4	0.08	1.9e-08	5.4	-5.2	2.1e-07	-0.68	0.00	1.00	FALSE
18	The Cancer Genome Atlas	Testicular Germ Cell Tumors	INPP5E	0.10	0.06	blup	54	0.08	8.1e-04	5.1	-5.3	1.1e-07	-0.86	0.02	0.82	FALSE