[Hub]/) : Traits : Whole body fat-free mass : ← →

chr10:4,236,655-5,844,628

Best TWAS P=7.64e-14 · Best GWAS P=1.51e-13 conditioned to 0.0982

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	AKR1C1	0.07	0.04	enet	10	0.02	1.0e-03	-7.2	7.5	7.6e-14	-0.88	0.00	0.99	TRUE
4	GTEx	Cells Transformed fibroblasts	AKR1C2	0.28	0.23	lasso	6	0.21	1.9e-15	-7.4	-7.4	1.2e-13	1.00	0.00	1.00	FALSE
5	GTEx	Esophagus Muscularis	AKR1C2	0.30	0.21	lasso	2	0.19	8.5e-12	-7.4	-7.4	1.2e-13	1.00	0.00	1.00	FALSE
8	GTEx	Skin Sun Exposed Lower leg	AKR1C2	0.17	0.18	lasso	2	0.18	4.0e-15	-7.3	-7.4	1.8e-13	1.00	0.00	1.00	FALSE
12	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	AKR1C2	0.12	0.11	lasso	6	0.09	1.6e-10	-7.4	-7.4	1.8e-13	1.00	0.00	1.00	FALSE
10	ROSMAP	Brain Pre-frontal Cortex	AKR1C2	0.56	0.40	enet	28	0.46	1.0e-65	-7.4	-7.3	3.6e-13	0.93	0.00	1.00	FALSE
6	GTEx	Heart Atrial Appendage	AKR1C2	0.28	0.37	lasso	3	0.29	1.2e-13	-7.2	-7.2	4.1e-13	0.98	0.00	1.00	FALSE
13	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	AKR1C2	0.29	0.21	lasso	1	0.21	4.7e-12	-7.2	-7.2	4.3e-13	0.98	0.00	1.00	FALSE
9	GTEx	Testis	AKR1C2	0.44	0.36	lasso	4	0.36	8.5e-17	-7.4	-7.1	9.7e-13	1.00	0.00	1.00	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	AKR1C2	0.39	0.18	enet	14	0.23	2.5e-23	-7.4	-7.0	1.9e-12	0.85	0.00	1.00	FALSE
17	The Cancer Genome Atlas	Thyroid Carcinoma	AKR1C2	0.09	0.08	lasso	3	0.08	7.2e-08	-7.2	-6.9	5.3e-12	0.90	0.00	1.00	FALSE
1	GTEx	Artery Tibial	AKR1C2	0.14	0.10	enet	10	0.15	1.2e-11	-7.2	-6.5	9.3e-11	0.94	0.00	1.00	FALSE
7	GTEx	Ovary	AKR1C3	0.35	0.20	lasso	9	0.22	3.9e-06	-7.4	-6.3	2.2e-10	0.91	0.01	0.97	FALSE
2	GTEx	Brain Cerebellar Hemisphere	AKR1C1	0.46	0.14	lasso	4	0.23	1.4e-06	-3.6	6.3	3.2e-10	-0.85	0.01	0.96	FALSE
3	GTEx	Brain Cortex	AKR1C2	0.49	0.10	lasso	11	0.26	1.1e-07	-7.4	-6.1	9.9e-10	0.85	0.01	0.98	FALSE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	AKR1C2	0.09	0.05	blup	62	0.05	3.4e-06	-7.2	-5.9	4.5e-09	0.89	0.00	1.00	FALSE
16	The Cancer Genome Atlas	Soft Tissue Sarcoma	AKR1C2	0.07	0.04	enet	5	0.06	1.1e-04	-3.6	-5.3	1.4e-07	0.74	0.01	0.81	FALSE