Best TWAS P=1.37e-08 · Best GWAS P=6.79e-09 conditioned to 0.179
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PIP4K2A | 0.20 | 0.18 | lasso | 1 | 0.18 | 6.4e-21 | 5.7 | -5.7 | 1.4e-08 | -0.94 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Artery Tibial | PIP4K2A | 0.06 | 0.01 | enet | 8 | 0.02 | 2.1e-02 | 5.4 | -5.2 | 2.6e-07 | -0.68 | 0.08 | 0.69 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | PIP4K2A | 0.24 | 0.20 | lasso | 2 | 0.19 | 2.9e-14 | 5.4 | -5.2 | 1.6e-07 | -0.81 | 0.04 | 0.96 | FALSE |