[Hub]/) : Traits : Whole body fat-free mass : ← →

chr11:26,818,083-29,054,545

Best TWAS P=1.1e-18 · Best GWAS P=1.04e-23 conditioned to 9.51e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous LIN7C 0.08 0.06 lasso 1 0.04 4.1e-04 8.43 8.4 3.5e-17 0.63 0.74 0.14 FALSE
2 GTEx Cells Transformed fibroblasts LIN7C 0.26 0.22 lasso 6 0.25 1.4e-18 8.43 7.3 2.0e-13 0.62 1.00 0.00 FALSE
3 GTEx Esophagus Muscularis LIN7C 0.14 0.08 enet 11 0.07 5.4e-05 3.92 6.4 1.2e-10 0.60 0.67 0.18 FALSE
4 GTEx Liver METTL15 0.18 0.05 lasso 3 0.09 1.9e-03 -0.13 -6.3 2.5e-10 -0.68 0.02 0.82 FALSE
5 GTEx Nerve Tibial LIN7C 0.18 0.08 enet 27 0.12 4.2e-09 8.43 5.8 8.1e-09 0.56 0.62 0.35 FALSE
6 GTEx Thyroid LIN7C 0.08 0.04 lasso 4 0.04 6.0e-04 8.43 8.4 4.7e-17 0.69 0.52 0.36 FALSE
7 NTR Blood LIN7C 0.01 0.00 lasso 3 0.01 2.2e-03 9.10 -8.8 1.1e-18 -0.72 0.09 0.83 TRUE
8 The Cancer Genome Atlas Bladder Urothelial Carcinoma LIN7C 0.04 0.01 lasso 3 0.02 1.0e-02 -2.12 5.5 4.7e-08 0.46 0.02 0.85 FALSE
9 The Cancer Genome Atlas Colon Adenocarcinoma LIN7C 0.10 0.03 blup 32 0.08 2.8e-05 8.66 6.4 1.2e-10 0.57 0.01 0.94 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LIN7C 0.05 0.02 lasso 3 0.03 2.9e-04 8.75 8.2 2.9e-16 0.63 0.00 0.98 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma LIN7C 0.09 0.12 lasso 2 0.12 2.6e-13 3.81 5.5 3.4e-08 0.52 0.94 0.06 FALSE