Best TWAS P=3.72e-08 · Best GWAS P=1.92e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Pituitary | PDE2A | 0.25 | 0.19 | lasso | 5 | 0.17 | 4.1e-05 | 5.3 | 5.3 | 1.4e-07 | 0.94 | 0.00 | 0.96 | FALSE |
| 2 | GTEx | Pituitary | RP11-169D4.2 | 0.19 | 0.20 | lasso | 2 | 0.16 | 7.3e-05 | 5.3 | 5.5 | 3.7e-08 | 0.98 | 0.00 | 0.96 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PDE2A | 0.02 | 0.02 | lasso | 2 | 0.02 | 2.0e-04 | 5.3 | -5.3 | 1.3e-07 | -0.94 | 0.01 | 0.95 | FALSE |