[Hub]/) : Traits : Whole body fat-free mass : ← →

chr12:27,587,038-29,432,481

Best TWAS P=1.01e-14 · Best GWAS P=4.06e-15 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Cells Transformed fibroblasts	RP11-967K21.1	0.07	0.07	lasso	2	0.07	3.7e-06	-7.5	7.7	1.0e-14	-0.96	0.05	0.95	TRUE
7	GTEx	Heart Atrial Appendage	RP11-967K21.1	0.08	0.09	lasso	1	0.08	2.3e-04	-7.5	7.5	4.7e-14	-0.91	0.04	0.92	FALSE
10	GTEx	Skin Sun Exposed Lower leg	CCDC91	0.09	0.01	enet	8	0.01	2.6e-02	-7.5	-7.5	7.7e-14	0.85	0.07	0.88	FALSE
3	GTEx	Cells Transformed fibroblasts	CCDC91	0.10	0.10	lasso	5	0.09	5.5e-07	-7.2	-7.4	1.8e-13	0.85	0.14	0.86	FALSE
15	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CCDC91	0.09	0.11	lasso	2	0.12	2.3e-05	-7.2	-7.2	6.9e-13	0.91	0.07	0.91	FALSE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	CCDC91	0.04	0.04	lasso	3	0.03	1.8e-06	-7.1	-7.1	1.3e-12	0.94	0.16	0.84	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	CCDC91	0.26	0.05	lasso	15	0.04	4.1e-03	-7.9	-7.0	2.5e-12	0.87	0.03	0.97	FALSE
8	GTEx	Muscle Skeletal	RP11-967K21.1	0.04	0.01	lasso	9	0.00	2.9e-01	-7.1	6.7	1.7e-11	-0.90	0.06	0.82	FALSE
16	The Cancer Genome Atlas	Thyroid Carcinoma	CCDC91	0.40	0.12	blup	175	0.14	4.9e-13	-7.4	-6.7	1.9e-11	0.72	0.06	0.94	FALSE
6	GTEx	Heart Atrial Appendage	CCDC91	0.10	0.06	lasso	8	0.04	4.4e-03	-7.2	-6.6	3.4e-11	0.85	0.04	0.91	FALSE
2	GTEx	Artery Aorta	RP11-967K21.1	0.07	0.02	lasso	7	0.01	7.9e-02	4.0	6.5	8.7e-11	-0.83	0.06	0.82	FALSE
5	GTEx	Colon Transverse	CCDC91	0.11	0.01	lasso	6	0.00	4.6e-01	-7.1	-6.5	9.3e-11	0.80	0.09	0.75	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CCDC91	0.08	0.06	lasso	6	0.07	9.4e-09	-7.1	6.1	8.4e-10	-0.87	0.27	0.73	FALSE
13	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CCDC91	0.06	0.02	blup	174	0.04	2.9e-05	3.1	-6.1	1.2e-09	0.79	0.39	0.59	FALSE
14	The Cancer Genome Atlas	Lung Adenocarcinoma	CCDC91	0.09	0.01	blup	170	0.02	1.0e-03	-7.3	-5.7	1.2e-08	0.75	0.15	0.73	FALSE
11	GTEx	Thyroid	CCDC91	0.15	0.12	enet	42	0.12	2.9e-09	-7.3	-5.5	5.0e-08	0.81	0.05	0.95	FALSE