TWAS hub - CCDC91

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0790	0.0280	1.6e-05	0.058	0.049	0.063	0.065	0.069	1.2e-07	1.3e-06	3.8e-08	2.2e-08	9.4e-09
2	GTEx	Adrenal Gland	0.1583	0.0690	6.1e-03	0.010	NA	0.004	NA	0.028	1.4e-01	NA	2.3e-01	NA	3.5e-02
3	GTEx	Artery Aorta	0.1630	0.0540	1.6e-04	-0.001	NA	0.016	NA	0.014	3.9e-01	NA	4.1e-02	NA	5.5e-02
4	GTEx	Cells Transformed fibroblasts	0.0990	0.0340	3.1e-05	0.103	NA	0.077	NA	0.086	3.8e-08	NA	2.2e-06	NA	5.5e-07
5	GTEx	Colon Transverse	0.1110	0.0440	2.0e-03	0.013	NA	-0.003	NA	-0.003	7.5e-02	NA	4.8e-01	NA	4.5e-01
6	GTEx	Esophagus Mucosa	0.1790	0.0620	1.5e-04	0.044	NA	0.032	NA	0.016	6.0e-04	NA	3.1e-03	NA	2.9e-02
7	GTEx	Heart Atrial Appendage	0.1000	0.0420	2.6e-03	0.058	NA	0.043	NA	0.045	1.4e-03	NA	5.0e-03	NA	4.4e-03
8	GTEx	Lung	0.1420	0.0480	1.5e-04	-0.004	NA	0.062	NA	0.017	8.8e-01	NA	1.5e-05	NA	1.6e-02
9	GTEx	Skin Not Sun Exposed Suprapubic	0.2630	0.0670	5.0e-07	0.045	NA	0.016	NA	0.037	1.7e-03	NA	4.2e-02	NA	4.1e-03
10	GTEx	Skin Sun Exposed Lower leg	0.0860	0.0340	3.5e-04	0.008	NA	0.013	NA	0.008	6.8e-02	NA	2.6e-02	NA	6.6e-02
11	GTEx	Thyroid	0.1480	0.0410	2.7e-09	0.121	NA	0.117	NA	0.115	1.5e-09	NA	2.9e-09	NA	4.2e-09
12	NTR	Blood	0.0118	0.0056	4.3e-03	0.005	0.005	0.001	0.004	0.003	5.6e-03	9.0e-03	9.8e-02	1.3e-02	2.7e-02
13	TCGA	Breast Invasive Carcinoma	0.0352	0.0215	1.1e-06	0.038	0.023	0.021	NA	0.028	2.9e-08	1.1e-05	3.0e-05	NA	1.8e-06
14	TCGA	Head and Neck Squamous Cell Carcinoma	0.0552	0.0309	1.3e-05	0.022	0.039	0.024	NA	0.026	1.4e-03	2.9e-05	8.4e-04	NA	6.2e-04
15	TCGA	Lung Adenocarcinoma	0.0858	0.0644	2.0e-04	0.011	0.023	0.014	NA	0.019	1.8e-02	1.0e-03	7.1e-03	NA	2.6e-03
16	TCGA	Pheochromocytoma and Paraganglioma	0.0910	0.0470	3.5e-04	0.114	0.095	0.094	NA	0.117	2.9e-05	1.3e-04	1.5e-04	NA	2.3e-05
17	TCGA	Prostate Adenocarcinoma	0.2175	0.0814	7.8e-03	-0.001	0.021	0.043	NA	-0.002	3.9e-01	2.8e-03	2.5e-05	NA	5.9e-01
18	TCGA	Thyroid Carcinoma	0.4010	0.0710	2.1e-15	0.121	0.135	0.099	NA	0.115	7.8e-12	4.9e-13	6.8e-10	NA	2.6e-11

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Lung FVC	35.7	181.8	309.8	-15.1	6.3	15.3	13.0	16.9	12.3	12.5	8.4	12.8	13.3	14.1	15.7	14.1	17.6	15.8	13.8	8.6	11.4
Standing height	18.5	183.2	275.6	13.9	-9.3	-11.2	-15.6	-14.7	-11.6	-15.3	-7.8	-16.0	-16.6	-11.9	-12.5	-15.9	-14.6	-14.1	-16.4	-9.5	-12.3
Mouth/teeth dental problems: Loose teeth	17.9	21.3	35.6	-5.1	1.5	3.4	4.3	5.6	4.4	4.8	3.4	6.0	5.3	5.0	5.4	4.9	5.7	4.9	5.1	2.4	2.9
Height	17.8	342.2	519.5	19.6	-12.3	-16.0	-21.5	-19.3	-15.8	-21.0	-10.5	-22.0	-22.1	-16.7	-16.6	-22.4	-18.8	-19.1	-22.8	-12.7	-17.5
Comparative height size at age 10	17.3	95.2	163.8	10.0	-6.8	-7.5	-11.8	-9.6	-7.3	-11.8	-5.9	-12.8	-11.6	-8.7	-8.3	-11.8	-9.0	-9.9	-12.1	-6.9	-9.8
Forced expiratory volume in 1-second (FEV1), predicted	15.6	32.5	51.8	6.1	-3.3	-4.7	-6.1	-6.0	-5.5	-6.6	-4.2	-7.2	-6.3	-5.5	-5.8	-6.8	-6.5	-5.4	-6.9	-2.9	-4.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	13.6	28.8	46.1	-5.8	2.0	6.4	5.9	6.7	4.5	4.6	3.0	5.1	5.2	5.8	6.6	5.6	6.8	6.3	5.5	3.2	4.6
Sitting height	8.8	62.5	112.4	9.0	-3.4	-6.8	-7.9	-9.9	-5.8	-6.6	-5.2	-8.8	-9.3	-8.0	-9.9	-8.4	-10.6	-8.5	-8.6	-5.4	-6.1
Trunk predicted mass	7.6	43.4	68.2	6.8	-5.4	-4.3	-7.9	-7.4	-5.7	-7.2	-2.6	-7.5	-8.3	-6.0	-5.7	-7.6	-6.9	-6.4	-7.8	-4.9	-7.3
Trunk fat-free mass	7.5	43.1	67.6	6.7	-5.4	-4.3	-8.0	-7.3	-5.6	-7.2	-2.5	-7.5	-8.2	-6.0	-5.7	-7.6	-6.9	-6.4	-7.8	-4.9	-7.4
Arm fat-free mass (left)	6.5	33.0	52.1	6.0	-4.9	-3.8	-7.0	-6.5	-4.6	-6.4	-1.5	-6.4	-7.2	-5.2	-4.9	-6.8	-6.2	-5.8	-6.9	-3.7	-6.2
Arm predicted mass (left)	6.5	33.1	50.7	6.1	-5.0	-4.0	-7.1	-6.6	-4.5	-6.4	-1.6	-6.6	-7.1	-5.3	-4.8	-6.8	-6.2	-5.7	-6.8	-3.5	-6.2
Arm predicted mass (right)	6.3	32.0	50.8	6.1	-4.6	-4.0	-6.5	-6.4	-4.7	-6.1	-1.9	-6.2	-7.1	-5.3	-4.8	-6.7	-6.2	-5.9	-6.8	-3.8	-5.9
Whole body fat-free mass	6.2	35.5	56.0	6.1	-5.1	-3.1	-7.4	-6.5	-4.9	-6.6	-2.4	-7.0	-7.5	-5.5	-5.1	-7.1	-6.1	-5.7	-7.2	-4.4	-6.7
Arm fat-free mass (right)	6.1	31.5	49.7	6.0	-4.5	-3.9	-6.6	-6.3	-4.7	-6.1	-1.7	-6.2	-7.0	-5.3	-4.7	-6.7	-6.1	-5.8	-6.8	-3.7	-5.8
Whole body water mass	6.0	34.2	53.9	6.0	-5.1	-3.1	-7.2	-6.4	-4.9	-6.5	-2.3	-6.8	-7.3	-5.3	-5.0	-6.9	-5.9	-5.5	-7.0	-4.3	-6.7
Basal metabolic rate	5.6	30.9	49.9	5.6	-5.0	-2.7	-7.1	-5.9	-4.5	-6.4	-2.1	-6.7	-7.1	-4.9	-4.5	-6.7	-5.4	-5.2	-6.8	-4.1	-6.4
Mouth/teeth dental problems: Bleeding gums	5.4	6.9	14.3	-3.1	0.7	2.7	1.7	3.0	1.4	1.9	1.1	2.7	2.9	3.3	3.3	2.9	3.1	3.8	3.0	2.1	2.2
Hand grip strength (left)	5.3	14.0	22.8	4.4	-4.1	-3.4	-3.5	-3.8	-4.1	-3.3	-1.1	-2.9	-4.5	-3.5	-2.8	-4.5	-3.7	-3.8	-4.8	-3.2	-4.4
Commuting to job workplace: Car/motor vehicle	5.1	5.8	11.9	-2.7	-0.8	1.3	2.4	3.1	2.3	2.9	0.5	2.0	2.6	2.1	3.0	2.3	3.4	3.1	2.3	2.5	2.1
Medication: Atorvastatin	5.0	6.1	10.4	-2.5	2.1	0.0	2.8	2.5	2.9	2.7	2.3	2.8	2.9	1.7	3.2	2.8	2.1	2.4	2.8	1.8	2.4
Frequency of unenthusiasm / disinterest in last 2 weeks	4.7	6.2	10.6	-3.2	2.2	1.0	2.9	2.9	2.5	2.9	2.0	2.3	2.6	2.3	2.5	3.0	2.0	2.6	3.2	0.8	2.4
Depression (Nagel 2018)	4.6	7.0	11.4	-3.1	1.8	0.7	3.3	3.1	1.9	3.4	2.3	2.7	2.5	2.4	2.9	3.2	2.5	2.9	3.1	1.0	2.8
Pulse wave reflection index	4.4	5.4	9.7	-3.0	1.4	1.8	2.5	2.4	1.1	2.6	1.4	2.2	2.3	2.4	1.9	3.1	2.5	2.9	3.0	2.1	1.9
Myopia	4.1	5.9	14.5	-3.0	3.8	2.4	1.7	2.9	2.0	1.0	1.6	3.1	2.7	2.8	2.4	2.8	1.9	1.5	2.7	0.6	2.6
Hand grip strength (right)	4.0	10.8	18.8	4.0	-4.0	-2.6	-3.4	-3.5	-2.6	-3.3	-0.1	-2.5	-4.3	-2.4	-2.3	-4.0	-3.1	-3.1	-4.3	-2.5	-4.2
Hair/balding pattern: Pattern 2	4.0	5.1	11.6	2.2	-1.3	-1.5	-2.5	-2.2	-1.6	-2.9	-1.6	-2.3	-0.7	-2.3	-1.7	-2.5	-2.7	-2.9	-2.0	-2.5	-3.4
Heart disease (mother)	3.8	4.6	17.4	-2.2	2.2	-0.3	2.3	1.8	4.2	1.0	3.0	2.7	1.5	1.9	2.6	2.1	1.1	0.4	1.8	0.9	2.6
Guilty feelings	3.8	5.8	10.1	-2.5	2.0	0.5	3.1	2.7	1.8	2.5	1.8	2.4	2.6	3.2	2.6	3.0	2.5	2.1	2.6	1.0	2.7
Mouth/teeth dental problems	3.7	5.8	12.2	2.8	-0.6	-1.6	-2.8	-2.8	-1.1	-2.1	-0.6	-2.5	-2.6	-3.5	-3.0	-3.0	-2.6	-2.8	-3.3	-1.2	-0.9
Leg fat-free mass (right)	3.7	19.5	33.2	4.4	-4.3	-0.9	-5.8	-4.5	-3.6	-5.1	-2.3	-5.6	-5.6	-3.8	-3.8	-5.4	-4.0	-3.6	-5.4	-3.4	-5.1
Leg predicted mass (right)	3.7	19.5	33.6	4.4	-4.3	-0.9	-5.8	-4.5	-3.5	-5.1	-2.3	-5.6	-5.5	-3.8	-3.7	-5.4	-4.0	-3.7	-5.5	-3.3	-5.1
Leg predicted mass (left)	3.5	18.5	32.3	4.2	-4.4	-0.6	-5.7	-4.3	-3.2	-5.0	-1.8	-5.4	-5.6	-3.7	-3.3	-5.3	-3.8	-3.5	-5.4	-3.4	-5.2
Headache pain in last month	3.5	6.0	11.2	-2.3	0.1	2.4	2.6	2.4	2.4	2.6	1.9	2.3	2.9	2.2	2.9	3.1	2.7	2.8	3.3	1.9	1.1
Leg fat-free mass (left)	3.4	18.3	32.0	4.1	-4.4	-0.6	-5.7	-4.2	-3.2	-4.9	-1.8	-5.4	-5.5	-3.7	-3.3	-5.2	-3.8	-3.5	-5.3	-3.4	-5.2
Pulse wave peak to peak time	3.4	4.0	7.0	2.2	-1.9	-2.3	-2.2	-2.0	-1.7	-2.6	-1.5	-1.9	-2.4	-1.8	-1.6	-2.3	-2.2	-2.1	-2.6	-0.7	-0.9
Medication: Omeprazole	3.4	4.1	8.8	3.0	0.5	-1.3	-2.7	-2.7	-0.5	-2.0	0.2	-2.3	-2.4	-1.5	-2.2	-2.7	-2.1	-2.1	-2.6	-0.6	-1.5
Current tobacco smoking	3.3	5.4	10.7	-2.7	1.9	2.2	2.3	2.5	1.8	2.9	0.7	1.4	2.8	2.4	2.3	2.8	2.9	3.2	3.3	0.6	0.7
Blood clot in the leg (DVT)	3.3	4.2	7.9	1.9	-2.3	-2.0	-2.8	-2.5	-1.5	-2.2	-1.2	-1.8	-2.0	-1.9	-1.9	-2.2	-2.2	-2.6	-2.1	-1.2	-2.0
Severe depression (siblings)	3.2	3.6	7.2	-2.7	0.7	1.7	1.8	1.8	1.1	2.0	2.1	2.3	1.4	1.9	2.7	2.5	2.2	1.7	2.2	0.7	0.9
Smoking status: Current	3.2	5.2	9.7	-2.6	1.8	2.3	2.2	2.5	1.8	2.8	0.9	1.0	2.5	2.4	2.3	2.7	2.8	3.1	3.1	0.6	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	3.1	9.9	21.0	-3.7	0.3	4.0	2.2	4.4	2.5	1.3	1.6	2.6	2.1	4.2	4.1	2.9	4.6	4.1	2.2	2.5	3.1
Impedance of leg (left)	3.0	14.8	48.8	4.0	-0.8	-7.0	-3.4	-4.0	-3.1	-4.1	-1.9	-3.6	-3.7	-3.2	-3.5	-4.3	-4.7	-5.3	-4.4	-1.8	-1.5
Weight	3.0	14.8	28.7	3.7	-4.2	-1.0	-5.2	-3.8	-2.5	-5.0	-0.5	-4.9	-5.4	-2.9	-2.4	-4.8	-3.1	-3.2	-4.9	-2.4	-4.6
Forced expiratory volume in 1-second (FEV1)	2.9	9.8	20.8	-3.7	0.7	4.3	2.2	4.5	3.0	1.2	2.2	2.5	2.1	4.6	4.3	2.6	4.4	3.5	2.0	2.2	2.7
Seen doctor (GP) for nerves, anxiety, tension or depression	2.9	4.4	6.6	-2.5	2.2	-0.2	2.2	2.4	1.8	2.6	1.1	1.6	2.0	2.4	2.5	2.1	2.5	2.3	2.0	1.7	2.2
Shortness of breath walking on level ground	2.9	3.4	7.6	2.1	0.1	-1.5	-1.5	-1.1	-1.1	-1.8	-1.0	-2.8	-2.5	-1.6	-2.0	-2.5	-2.0	-2.6	-2.3	-1.6	-0.7
Overall health rating	2.8	6.1	13.1	-2.7	2.1	0.6	1.5	1.8	3.3	2.4	3.1	2.3	1.9	2.4	2.2	2.5	2.4	2.6	2.8	3.6	2.6
Frequency of depressed mood in last 2 weeks	2.7	3.8	6.9	-2.2	0.8	0.6	1.9	1.8	1.9	2.3	1.7	1.9	2.0	1.9	2.0	2.4	1.6	2.4	2.6	1.5	2.3
BMI	2.5	14.6	26.7	-4.0	0.1	4.8	3.4	3.8	3.4	3.0	3.7	3.7	3.6	4.3	4.3	4.2	5.1	5.2	4.3	2.9	1.6
Chronic bronchitis/emphysema (mother)	2.5	2.9	6.3	0.9	-1.5	-1.8	-2.2	-2.0	-2.3	-2.0	-0.3	-2.0	-2.0	-0.9	-0.5	-1.9	-0.8	-1.0	-1.8	-1.9	-2.5
Osteoporosis (self-reported)	2.5	3.1	5.8	2.4	0.0	-1.8	-2.2	-2.3	-1.5	-1.7	-0.4	-1.9	-1.4	-2.0	-1.4	-2.2	-1.7	-2.2	-2.1	-1.1	-1.0
Commuting to job workplace: Public transport	2.5	3.0	7.4	1.4	-0.3	-0.3	-1.8	-2.0	-1.9	-2.5	-2.7	-0.8	-2.2	-1.7	-1.6	-1.5	-2.2	-1.9	-1.7	-1.5	-0.9
Major Depression (MDD)	2.4	2.9	5.9	-1.8	0.6	1.4	1.1	1.9	1.8	2.0	0.6	1.2	1.9	2.4	2.2	1.6	2.4	2.2	1.6	1.4	0.8
Heel T-Score	2.4	18.9	59.1	4.4	-5.3	-1.6	-5.4	-2.7	-2.3	-3.5	-2.2	-7.7	-5.4	-3.0	-4.1	-6.2	-1.8	-3.1	-6.1	-2.4	-4.8
Ever used hormone-replacement therapy (HRT)	2.4	3.0	7.2	-1.3	2.7	0.5	1.5	1.2	2.6	1.6	1.9	1.5	1.2	1.4	1.8	1.7	1.7	1.4	1.5	2.2	2.2
Comparative body size at age 10	2.4	6.7	11.8	-3.1	2.6	2.4	3.2	2.6	1.9	3.4	1.0	2.5	3.0	2.3	1.4	3.3	2.4	2.9	3.3	0.7	2.1
Deep venous thrombosis (DVT) (self-reported)	2.4	3.1	5.7	1.7	-2.2	-1.3	-2.4	-2.1	-1.2	-1.9	-1.2	-1.6	-1.7	-1.6	-1.5	-2.0	-1.8	-2.2	-1.8	-1.1	-1.8
Impedance of leg (right)	2.3	11.0	38.0	3.4	-0.9	-6.2	-2.9	-3.4	-2.5	-3.5	-1.2	-2.9	-3.4	-2.9	-2.6	-3.7	-4.0	-4.6	-3.9	-1.8	-1.6
Time employed in main current job	2.3	2.7	6.1	1.7	-0.4	-1.1	-1.8	-1.6	-1.3	-1.8	-1.2	-2.2	-2.0	-1.3	-2.5	-2.1	-1.2	-1.3	-1.8	-1.3	-1.7
Hair/balding pattern: Pattern 3	2.3	3.5	9.0	-1.6	0.1	1.4	2.4	2.1	2.0	3.0	1.2	1.3	1.3	2.2	2.2	1.7	2.1	2.4	1.5	1.5	1.7
Forced vital capacity (FVC), Best measure	2.3	8.5	22.2	-3.5	-0.4	4.4	1.6	4.2	2.6	1.1	1.7	1.5	1.5	4.1	4.0	2.1	4.7	3.9	1.6	2.0	2.2
Age at last live birth	2.3	3.3	7.6	1.7	0.2	-1.6	-1.6	-1.4	-1.6	-1.2	-1.2	-2.0	-1.8	-1.7	-2.3	-2.0	-1.7	-2.4	-2.2	-2.8	-1.7
Illnesses of father: Heart disease	2.3	3.1	5.3	-2.2	1.6	0.7	1.9	1.8	1.6	1.8	1.9	1.9	1.6	2.0	1.2	2.3	1.8	2.1	2.0	1.3	1.7
Wears glasses or contact lenses	2.3	2.6	6.0	-1.4	1.0	1.4	2.4	2.4	1.4	1.2	0.4	1.8	1.1	1.7	2.4	1.7	1.5	1.2	1.4	1.4	1.7
Heart attack/myocardial infarction (self-reported)	2.3	3.0	5.2	-2.2	-0.1	0.3	1.7	2.2	1.7	2.2	1.4	1.9	2.1	1.2	2.3	2.1	1.8	1.5	2.3	0.5	1.3
Fed-up feelings	2.2	4.0	7.5	-2.7	2.2	1.4	1.9	2.0	1.9	2.0	1.3	2.5	2.4	1.5	1.8	2.3	1.8	1.7	2.7	1.0	1.9
Frequency of tenseness / restlessness in last 2 weeks	2.2	3.4	7.4	-2.7	0.1	1.0	2.7	1.9	0.3	2.2	1.2	1.2	1.7	2.1	1.9	2.6	1.4	2.3	2.3	1.0	2.0
Medication: Atenolol	2.1	2.6	7.8	-2.3	1.3	0.4	1.5	1.0	2.2	1.4	0.2	1.4	1.0	1.2	0.9	2.1	1.3	1.9	1.7	2.1	2.8
Pain type(s) experienced in last month: Hip pain	2.1	2.6	8.4	-2.2	0.6	2.9	0.9	2.1	1.8	0.9	1.6	0.9	0.6	1.4	2.3	1.5	2.3	1.6	1.5	0.4	0.9
Forced vital capacity (FVC)	2.0	7.6	21.1	-3.2	0.2	4.6	1.3	4.0	2.7	0.7	2.3	1.4	1.3	3.9	4.1	1.8	4.2	3.1	1.3	1.6	1.9
Number of live births	2.0	2.9	6.7	-2.0	1.0	0.9	2.2	1.9	0.9	2.1	-0.8	0.7	2.4	2.6	1.0	2.2	2.0	1.6	2.1	0.7	1.0
Medication: Blood pressure	2.0	3.4	6.1	-2.5	1.1	0.2	1.9	2.2	2.4	1.7	1.8	1.4	1.6	1.4	2.4	2.1	1.7	1.9	2.3	1.6	1.8
Heart disease (siblings)	2.0	2.4	6.7	-1.9	-0.1	-0.4	1.3	1.5	1.5	1.3	1.5	1.4	2.0	1.1	2.6	1.8	2.3	1.8	1.8	0.1	0.1
Bipolar Disorder (2018)	1.9	3.0	5.6	-2.0	2.4	1.0	0.9	1.4	1.7	2.1	0.9	1.2	1.4	1.9	1.0	2.0	1.7	2.1	2.0	2.1	2.2
Trunk fat mass	1.9	8.4	20.8	2.6	-3.1	-0.3	-4.2	-2.5	-1.4	-4.6	0.0	-3.8	-4.2	-2.0	-1.1	-3.9	-1.9	-2.3	-3.9	-1.3	-3.0
Heart attack	1.9	2.5	4.4	-2.0	-0.0	0.1	1.5	2.0	1.6	1.9	1.6	1.9	1.9	1.0	2.1	1.9	1.6	1.2	2.1	0.2	1.0
Pulse rate, automated reading	1.9	6.0	16.4	3.3	0.1	2.0	-1.7	-2.3	-1.6	-1.4	-0.2	-2.0	-2.6	-4.0	-2.9	-3.1	-2.4	-2.6	-3.1	-2.6	-2.2
Depressed Affect (Nagel 2018)	1.8	3.8	6.8	-2.6	1.6	0.7	2.1	2.3	1.6	2.1	1.5	2.1	2.4	2.1	2.0	2.1	2.2	1.4	2.4	1.3	1.9
Heel bone mineral density (BMD) T-score, automated (right)	1.8	4.2	8.4	2.1	-2.7	-1.2	-2.5	-1.7	-0.9	-1.8	-2.1	-2.8	-2.5	-2.0	-2.9	-2.5	-1.4	-0.9	-2.8	-0.1	-1.1
Chest pain or discomfort	1.8	2.6	5.5	-1.5	1.6	1.0	1.4	1.4	2.1	1.7	2.4	1.7	2.2	1.8	1.5	1.6	1.0	1.1	1.7	1.6	1.0
Mineral and other dietary supplements	1.8	2.4	5.9	-1.4	0.6	1.1	1.5	1.6	1.4	1.1	-0.4	1.6	2.1	1.7	1.4	1.7	1.9	2.4	1.8	1.1	1.3
Osteoarthritis (self-reported)	1.8	2.3	6.9	-2.6	2.1	1.0	1.1	1.0	1.3	1.2	0.4	1.2	1.4	2.0	1.7	2.2	1.1	0.3	2.0	-1.7	0.8
Medication: Ramipril	1.7	2.1	6.8	-1.7	2.1	1.5	1.2	1.3	2.6	1.0	0.7	1.6	0.8	1.1	1.8	1.5	1.3	1.0	1.3	0.9	1.4
Hip circumference	1.7	7.3	16.6	2.6	-2.5	1.2	-3.7	-2.2	-1.3	-3.2	0.2	-3.6	-4.1	-1.9	-1.8	-3.8	-1.9	-2.3	-4.1	-1.6	-2.9
Medication: Lansoprazole	1.7	2.0	5.6	-2.4	0.1	1.0	1.1	1.3	1.6	0.6	1.2	0.6	1.8	1.0	2.1	1.8	1.6	1.5	1.8	0.3	0.9
Angina (self-reported)	1.7	2.2	7.4	-1.1	0.6	-0.3	1.0	0.9	2.4	1.4	1.1	2.7	1.2	0.5	2.2	1.2	1.0	1.2	1.2	1.7	2.2
Impedance of whole body	1.7	8.8	17.0	3.0	-0.8	-4.1	-3.0	-2.8	-2.3	-3.7	-2.3	-3.6	-3.4	-2.3	-2.8	-3.6	-3.1	-3.5	-3.8	-1.5	-0.9
Primary Biliary Cirrhosis	1.6	2.3	5.6	2.4	-1.4	-1.4	-1.1	-1.3	-0.6	-1.3	0.3	-2.3	-1.7	-0.9	-1.1	-1.9	-1.5	-1.5	-1.6	-0.8	-2.2
Medication for hormone replacement therapy	1.6	1.8	5.6	-1.5	0.5	0.9	1.3	1.3	1.4	1.2	1.0	1.9	0.8	1.4	1.3	1.2	1.3	1.4	0.9	1.4	2.4
Body mass index (BMI)	1.6	6.7	17.4	-2.6	-0.0	4.2	1.7	2.8	2.7	1.7	3.1	2.3	2.1	2.5	3.3	2.3	3.5	3.2	2.5	1.9	0.8
Type 2 Diabetes (T2D) (2012)	1.5	1.7	5.3	1.8	0.2	-2.3	-0.2	-1.2	-1.3	-0.7	-0.7	-1.5	-2.1	-0.9	-1.3	-1.5	-1.9	-1.1	-1.8	-0.1	-0.5
Waist Hip Ratio (WHR)	1.5	6.6	18.3	1.6	-2.5	-4.3	-3.5	-2.2	-3.1	-3.8	-3.2	-1.9	-2.6	-2.5	-0.5	-2.6	-1.3	-1.8	-2.6	-1.0	-1.8
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.5	5.4	-1.8	1.4	1.0	1.1	1.1	2.1	1.1	2.3	1.2	0.7	1.4	1.9	1.8	1.3	1.7	1.9	1.7	1.6
Falls in the last year	1.5	2.1	7.7	-0.8	2.8	0.5	2.1	1.4	2.4	1.4	0.4	0.8	1.2	1.2	0.9	0.9	0.4	0.6	0.9	1.5	2.3
Migraine (self-reported)	1.5	1.9	6.8	-1.7	-0.0	0.5	1.3	1.6	1.0	1.1	1.3	1.6	1.0	1.1	2.6	1.4	2.2	1.2	1.3	-0.8	0.5
Arm fat percentage (left)	1.5	6.0	19.5	-2.6	-0.7	4.4	1.3	2.9	2.5	0.9	2.1	1.5	1.8	2.5	3.5	1.9	3.8	3.2	1.9	1.8	0.9
Neuroticism (Nagel 2018)	1.4	3.2	5.8	-2.3	1.8	0.1	2.1	2.4	1.2	2.1	1.9	1.7	1.7	1.9	2.1	1.9	2.0	0.6	1.7	0.9	2.1
Maternal smoking around birth	1.4	2.0	10.1	-1.4	-0.0	0.6	1.0	0.7	0.9	1.2	3.2	1.9	1.0	1.8	1.4	1.7	1.4	1.3	1.6	1.1	1.1
Ever unenthusiastic/disinterested for a whole week	1.4	1.7	4.9	-1.0	1.4	0.1	1.1	0.8	2.2	1.0	1.8	1.6	1.1	1.0	1.4	1.2	1.2	1.4	1.3	1.5	1.0
Pain all over the body in last month	1.4	1.5	3.8	1.3	1.0	-1.2	-1.0	-1.6	-1.8	-0.6	-1.4	-0.9	-0.7	-1.8	-2.0	-1.3	-1.3	-1.2	-1.2	-0.2	-0.5
Medication for cholesterol	1.4	2.2	6.7	1.3	-1.3	0.4	-1.4	-0.5	-2.3	-1.1	-2.6	-2.5	-0.7	-0.9	-1.6	-1.7	-0.8	-0.8	-1.4	-1.2	-1.4
Medication: Gliclazide	1.4	1.5	3.6	-0.9	-0.1	-0.3	1.4	1.1	0.1	1.8	-0.6	1.3	1.6	1.0	0.9	1.3	1.5	1.9	1.4	1.8	1.0
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	3.8	1.7	1.2	-0.9	-2.0	-1.8	-0.1	-1.1	0.0	-1.5	-1.5	-0.7	-1.5	-1.6	-1.4	-1.5	-1.5	-0.6	-1.1
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	4.5	-1.4	1.9	0.1	1.2	0.4	0.9	1.0	0.9	2.0	0.4	1.0	0.9	1.4	0.3	1.1	1.1	1.5	2.1
Heel bone mineral density (BMD) T-score, automated (left)	1.3	2.9	10.3	1.9	-3.2	-1.1	-1.8	-1.3	-0.2	-1.2	-1.1	-2.5	-2.0	-1.5	-2.1	-2.2	-0.7	-0.3	-2.3	0.6	-1.0
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.5	3.6	-1.8	-0.4	-0.6	1.3	1.1	1.1	1.3	0.6	0.9	1.1	1.2	1.7	1.7	1.7	1.9	1.4	0.5	0.5
Illnesses of siblings: Diabetes	1.3	1.6	4.2	1.3	-0.5	-1.3	-0.9	-1.1	-2.0	-0.9	-0.4	-1.4	-1.3	-1.2	-1.2	-1.5	-1.3	-1.5	-1.3	-1.2	-1.3
High blood pressure (mother)	1.2	1.7	5.1	-1.4	-0.2	0.1	1.7	1.4	1.3	1.8	1.5	2.3	1.3	0.5	0.9	1.5	0.5	0.4	1.0	0.7	2.2
Had menopause	1.2	1.5	4.9	1.4	0.5	-1.5	-1.2	-1.0	0.0	-1.9	0.2	-0.8	-1.5	-1.5	-0.6	-1.4	-1.2	-2.2	-1.5	-0.4	-0.5
Neuroticism score	1.2	2.6	5.5	-2.1	1.6	0.4	1.6	1.6	1.5	1.6	1.9	1.4	1.3	1.8	1.5	2.0	1.4	1.0	1.8	0.9	2.3
Arm fat percentage (right)	1.2	4.8	16.5	-2.3	-0.8	4.1	0.8	2.5	2.4	0.5	2.1	1.2	1.5	2.2	3.1	1.6	3.4	3.0	1.7	1.9	0.5
Alcohol intake versus 10 years previously	1.2	1.7	4.3	1.6	-0.9	-0.7	-0.9	-1.2	-1.0	-1.4	-1.0	-2.1	-1.2	-1.1	-1.3	-1.5	-1.8	-1.2	-1.3	-1.2	-1.6
Peak expiratory flow (PEF)	1.2	2.9	5.8	-2.0	0.2	2.0	1.2	2.0	0.9	-0.1	2.3	2.3	1.3	2.4	2.2	1.8	1.9	1.6	1.1	1.3	1.2
Age at first live birth	1.2	2.1	4.4	1.3	0.5	-0.6	-1.5	-1.8	-1.7	-0.9	0.1	-0.9	-2.0	-1.4	-2.1	-1.5	-1.4	-1.4	-2.0	-1.6	-1.3
Medication for pain relief, constipation, heartburn	1.2	2.1	5.1	0.6	0.1	-1.0	-1.8	-1.3	-1.8	-2.3	-1.4	-1.7	-2.2	-0.7	-1.7	-1.3	-1.5	-1.4	-1.5	-1.3	-0.6
Ever depressed for a whole week	1.2	1.5	5.5	-0.9	2.3	-1.3	1.1	0.6	1.3	1.2	1.9	1.9	1.1	0.4	0.3	0.9	0.2	0.5	0.8	0.7	1.6
Crohns Disease (2017)	1.1	2.3	5.8	2.0	-0.9	-0.8	-1.3	-0.9	-1.8	-1.3	0.1	-1.7	-1.6	-1.5	-1.2	-2.3	-1.3	-1.3	-2.4	-1.7	-1.5
Smoking Status	1.1	2.7	6.0	-2.4	0.9	1.6	1.5	1.7	-0.1	1.9	0.1	1.4	1.4	1.7	1.5	2.0	2.1	2.2	2.2	1.1	1.1
Angina	1.1	1.4	4.8	-0.6	0.1	-0.4	0.7	0.6	2.1	1.1	0.9	2.2	0.9	0.2	1.9	0.8	0.8	1.0	0.8	1.5	1.8
Hearing difficulty/problems with background noise	1.1	1.8	6.0	-1.2	-2.0	0.9	0.6	1.3	-0.6	1.0	-0.0	0.9	0.8	1.2	2.3	0.9	2.4	2.5	0.9	0.9	-0.1
Financial difficulties in last 2 years	1.1	1.5	2.9	-1.1	1.4	0.8	1.6	1.3	0.3	1.4	-1.1	0.8	1.5	0.9	1.6	1.7	0.7	1.1	1.6	0.5	1.4
Hayfever/allergic rhinitis (self-reported)	1.1	1.4	3.8	1.0	0.2	-1.1	-1.1	-1.0	-2.0	-1.0	-1.4	-1.1	-1.3	-1.8	-1.3	-1.2	-1.5	-1.2	-1.3	-0.0	0.3
Exposure to tobacco smoke outside home	1.1	1.5	3.5	-0.7	0.3	1.1	1.4	1.4	1.3	1.8	0.2	0.4	1.6	1.4	1.5	0.9	1.7	1.9	1.2	0.1	0.7
Worry too long after embarrassment	1.1	1.9	4.4	-1.0	1.9	0.2	1.4	1.7	1.8	1.1	2.1	1.1	0.5	1.5	1.2	1.2	1.3	0.9	1.0	1.4	2.1
Whole body fat mass	1.1	4.8	11.9	1.8	-3.0	0.2	-3.2	-1.8	-0.7	-3.5	0.6	-2.8	-3.2	-1.2	-0.3	-2.9	-1.0	-1.5	-2.9	-0.8	-2.7
Had major operations	1.1	1.3	2.8	-1.6	-1.6	-0.6	0.7	0.7	0.7	1.2	1.4	1.4	0.5	1.1	1.6	1.6	0.6	0.4	1.7	-0.6	0.3
Average weekly champagne plus white wine intake	1.1	1.5	4.0	1.4	-0.7	-0.2	-1.3	-1.1	-1.2	-1.6	-0.6	-1.2	-2.0	-0.4	-1.3	-1.7	-1.4	-1.3	-1.9	-0.3	-0.3
Allergy or Eczema	1.0	2.6	4.8	1.6	0.9	-1.7	-2.2	-2.0	-0.3	-1.3	1.5	-2.0	-2.0	-1.9	-1.7	-1.6	-1.7	-2.0	-1.6	-0.1	-0.7
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	4.4	1.4	-1.2	0.8	-1.4	-1.1	-2.1	-1.3	-1.5	-0.8	-0.9	-1.3	-1.1	-1.6	-0.4	-0.6	-1.6	-1.2	-1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	3.3	1.4	-1.8	-1.1	-0.8	-1.3	-1.2	-0.9	-1.7	-0.2	-0.7	-1.6	-0.1	-0.7	-1.4	-0.4	-0.4	0.1	-1.1
Average weekly beer plus cider intake	1.0	1.5	4.2	1.4	-1.0	0.1	-2.1	-1.8	0.2	-1.9	-0.3	-1.4	-1.0	-1.0	-1.3	-1.1	-1.7	-0.4	-1.1	-0.1	-1.1
Mean Putamen Volume	0.9	1.0	3.3	-0.3	-0.2	1.4	0.8	0.6	1.3	1.0	1.8	1.2	1.2	0.7	0.9	0.7	0.5	1.5	1.0	1.1	-0.1
LDL Cholesterol	0.9	1.4	5.4	-0.8	0.8	0.3	0.6	1.4	1.3	1.3	-0.6	0.1	0.7	0.7	1.1	0.8	1.5	2.0	0.8	1.6	2.3
Relative age of first facial hair	0.9	1.9	6.2	-1.2	0.4	0.0	1.1	1.2	1.2	1.1	2.5	1.9	1.0	1.2	1.5	1.2	1.3	1.3	1.0	2.3	1.3
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	3.6	0.8	-0.6	-1.1	-1.0	-0.5	-0.6	-0.5	-1.9	-1.5	-0.5	-0.3	-0.4	-1.1	-0.7	-1.1	-0.9	-1.5	-1.3
Townsend deprivation index at recruitment	0.9	1.3	3.5	1.4	-0.7	-0.5	-1.0	-1.1	-0.3	-0.6	-1.0	-1.3	-0.9	-1.2	-1.0	-1.3	-0.6	-1.2	-1.2	-1.7	-1.9
Serious illness, injury or assault to yourself	0.9	1.1	2.3	-1.2	0.1	-0.3	0.9	1.1	1.0	1.4	1.2	0.6	1.3	1.4	0.9	1.2	1.2	1.5	1.0	0.5	0.7
Allergy	0.9	2.0	4.7	-1.0	-0.1	1.4	2.1	1.6	0.9	1.0	-0.0	1.7	1.5	1.5	2.1	1.5	1.7	2.2	1.4	0.3	0.6
Noisy workplace	0.9	1.1	7.0	1.4	0.1	-2.6	-0.5	-0.7	-0.9	-0.7	-0.8	-1.3	-0.6	-1.0	0.1	-1.1	-0.6	-0.9	-0.7	0.0	-1.3
Illnesses of mother	0.9	1.1	2.7	1.1	0.6	1.4	-1.2	-1.0	-1.7	-1.2	-1.2	-1.6	-0.9	-0.2	-1.0	-1.2	-0.6	-0.5	-0.9	-0.2	-1.3
Pulse wave Arterial Stiffness index	0.9	1.1	2.3	-1.1	1.2	1.5	1.0	1.0	0.8	1.5	0.9	0.7	1.2	0.9	0.6	1.1	1.1	1.0	1.3	-0.3	-0.1
Birth weight of first child	0.9	1.6	4.3	1.1	-1.2	-0.6	-1.2	-0.9	-0.9	-1.7	0.1	-1.2	-1.3	-1.2	0.7	-1.3	-0.9	-1.2	-1.3	-2.1	-1.9
Ever highly irritable/argumentative for 2 days	0.9	1.0	4.9	-0.6	2.2	1.8	1.5	0.6	-0.7	0.9	-0.8	1.0	-0.2	0.7	-0.1	0.5	-0.0	0.5	0.3	0.9	1.6
Medication: Ventolin 100micrograms inhaler	0.9	1.2	3.2	1.2	-1.0	-1.7	-1.1	-0.9	-1.8	-0.6	0.5	-0.8	-0.9	-0.3	-1.6	-1.3	-0.8	-0.8	-1.4	0.4	-0.9
Medication: Aspirin	0.9	1.1	3.1	-1.0	-0.1	-1.0	1.0	0.5	1.8	1.6	1.3	1.0	1.6	0.6	0.7	1.3	0.4	0.7	1.3	1.1	0.2
Knee pain experienced in last month	0.9	1.4	3.9	0.8	-1.0	-1.5	-2.0	-0.9	-1.9	-1.4	-0.9	-1.2	-1.4	-0.9	-0.7	-1.5	-0.2	0.0	-1.5	-0.9	-1.1
Mood swings	0.9	1.6	5.7	-1.2	0.3	1.3	0.7	0.8	1.5	1.1	2.4	1.8	0.7	1.3	1.2	1.2	1.2	1.1	1.5	1.1	0.8
Long-standing illness, disability or infirmity	0.9	1.4	4.5	-1.7	2.1	-1.4	0.5	1.0	0.9	1.2	0.2	0.5	1.2	1.5	1.6	1.5	0.8	0.3	1.4	0.5	1.1
Back pain experienced in last month	0.9	1.3	2.4	1.0	-1.5	-0.4	-1.4	-1.3	0.1	-1.3	-0.5	-1.6	-1.2	-1.2	-1.3	-1.1	-1.5	-1.3	-0.5	-1.1	-1.3
Financial situation satisfaction	0.9	1.1	3.4	-1.0	0.8	1.3	1.2	0.8	0.6	0.9	-1.1	0.5	1.4	1.3	0.7	1.2	0.4	0.8	1.3	0.7	1.9
Medication: Blood pressure	0.9	1.7	5.7	-0.9	2.1	-1.8	1.0	0.2	2.4	-0.0	2.2	1.7	0.6	0.7	1.0	1.2	-0.1	-0.4	1.0	1.3	1.2
Irritability	0.9	1.5	3.1	-1.5	0.7	1.4	0.6	1.3	1.1	1.3	1.4	1.8	1.3	0.8	1.2	1.1	1.3	1.1	1.4	0.6	1.3
Ulcerative Colitis	0.8	1.2	4.1	-0.8	1.6	0.8	1.6	0.9	0.4	2.0	-0.3	0.1	0.4	1.8	0.7	1.2	0.6	1.3	0.8	1.0	1.2
Qualifications: CSEs or equivalent	0.8	1.1	7.5	-0.5	0.6	0.9	0.4	0.7	-0.2	1.2	-2.7	0.3	1.6	-0.1	-1.0	0.5	0.7	1.2	0.4	0.1	1.6
Medication: Levothyroxine sodium	0.8	1.3	7.2	-0.5	1.3	1.5	0.8	1.0	2.7	0.3	1.4	0.6	0.4	1.5	1.1	0.6	1.0	0.7	0.7	0.9	0.6
Waist circumference	0.8	2.9	7.8	1.0	-2.5	0.2	-2.8	-1.2	-0.9	-2.7	0.4	-1.7	-2.8	-1.2	-0.0	-2.2	-0.3	-1.0	-2.3	-0.5	-1.8
Fluid intelligence score	0.8	1.6	9.7	-0.6	0.3	1.9	1.0	0.7	2.0	1.1	3.1	1.9	0.1	1.0	0.6	0.9	0.6	0.4	0.5	1.1	0.6
Prospective memory result	0.8	1.0	4.4	0.4	-0.1	-1.6	-0.5	-0.3	0.8	-1.2	-1.0	-1.2	0.1	-0.3	0.9	-0.7	-0.5	-1.5	-0.2	-2.1	-1.3
Loud music exposure frequency	0.8	0.9	2.9	-1.0	0.9	0.4	-0.1	0.6	-0.5	0.1	0.8	1.4	1.2	0.5	1.7	1.0	1.4	1.1	0.6	0.8	1.2
Medication: Seretide 50 evohaler	0.8	0.9	2.2	0.8	-1.2	-1.5	-0.9	-1.0	-0.9	-1.4	-0.8	-1.4	-1.1	-0.1	-0.4	-0.8	-0.7	-0.7	-0.7	0.1	-1.2
Breast cancer (self-reported)	0.8	0.9	2.5	1.2	0.5	-0.3	-0.4	-0.8	-0.4	-1.1	-1.3	-1.6	-1.1	-1.3	-1.2	-1.1	-0.5	-0.2	-1.3	-0.8	-0.1
Medication: Aspirin	0.8	1.0	2.7	-0.9	-0.1	-1.0	1.0	0.5	1.5	1.6	1.0	0.9	1.6	0.7	0.7	1.3	0.3	0.8	1.3	0.7	0.2
Fasting Glucose	0.7	0.8	4.8	0.1	-0.4	-0.9	-0.1	-0.7	-1.6	0.2	-0.2	-0.1	-0.5	0.3	-0.8	-0.3	-1.1	-0.9	-0.3	-2.2	-1.8
Hearing difficulty/problems: Yes	0.7	1.0	3.9	-0.7	-0.8	-1.1	0.4	1.2	0.2	0.6	-0.4	0.1	1.5	1.3	2.0	0.7	1.7	1.3	0.8	0.5	0.0
Medication: Metformin	0.7	1.0	3.2	-0.9	0.9	-1.0	1.4	0.8	0.0	1.7	0.3	1.8	1.1	1.4	0.6	1.1	0.5	0.6	1.0	1.0	0.6
Impedance of arm (right)	0.7	3.3	8.9	1.2	-0.8	-1.4	-2.6	-1.1	-1.1	-2.9	-2.5	-3.0	-2.0	-1.0	-1.5	-2.3	-1.0	-1.3	-2.5	-0.9	-0.8
Happiness	0.7	0.9	4.2	-0.1	1.5	0.3	0.3	-0.4	-0.2	0.6	1.6	2.1	-0.6	0.6	-0.9	-0.0	-0.4	-0.2	-0.2	1.3	1.4
Lung cancer (father)	0.7	0.9	6.7	0.8	-0.2	-0.2	-0.6	-0.7	-0.5	-0.1	-2.6	-0.4	-0.2	-0.7	-1.6	-0.7	-1.4	-1.1	-0.6	0.2	0.1
Birth weight	0.7	1.5	11.1	1.7	-3.3	-0.1	-0.7	-0.5	0.3	-0.8	0.4	-1.6	-1.5	-1.0	0.8	-1.2	-0.5	-0.1	-1.2	-0.3	-1.3
Ever had bowel cancer screening	0.7	0.8	1.8	-1.2	1.1	-0.8	1.0	0.6	-0.7	0.5	-0.5	0.6	0.4	1.0	1.0	1.4	0.7	0.7	1.1	0.8	1.0
Miserableness	0.7	1.2	3.2	-1.0	-1.2	1.4	0.6	0.7	0.7	1.0	-0.1	0.4	0.4	1.3	1.2	0.9	1.2	1.5	0.9	1.8	1.4
Illnesses of father: High blood pressure	0.7	0.8	2.3	1.1	0.6	-0.8	-1.1	-1.3	-0.1	-1.5	-0.8	-1.1	-0.9	-0.3	-1.3	-0.8	-1.1	-0.3	-0.9	0.7	0.1
Risk taking	0.7	1.1	3.4	-0.1	-1.8	0.2	1.0	0.1	-0.6	0.7	-1.1	-0.0	0.2	0.9	0.9	0.9	0.9	1.8	0.8	1.8	1.5
Age started oral contraceptive pill	0.7	0.9	5.1	-0.4	2.3	-2.0	0.9	0.6	1.1	0.8	0.5	0.1	0.2	0.3	1.5	0.5	-0.1	-0.7	0.7	-0.2	-0.4
Cholesterol lowering medication	0.7	1.0	4.4	-0.4	0.1	-2.1	0.9	0.0	1.7	0.4	1.4	1.6	0.5	0.3	1.2	0.8	0.5	1.0	0.8	0.7	0.3
Alzheimer’s Disease (in mother)	0.6	0.7	1.9	-1.1	0.8	-0.9	0.9	0.8	0.0	0.6	-0.6	1.0	1.1	0.7	0.2	1.4	0.6	0.7	1.3	0.1	1.0
Verbal and Numeric Reasoning (VNR)	0.6	1.4	6.8	-1.0	0.5	2.1	0.9	0.9	1.2	0.5	2.6	2.2	0.4	0.6	1.5	1.0	0.8	0.3	0.7	0.3	0.1
Triglycerides	0.6	1.0	3.5	-1.3	0.1	1.4	0.2	1.0	0.1	1.0	-1.2	0.7	0.9	0.1	0.3	1.1	1.7	1.9	1.2	0.8	0.8
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	2.8	-1.1	1.7	-0.4	0.8	1.1	0.3	0.6	-0.5	0.1	0.2	1.1	1.0	0.8	1.1	0.2	0.8	0.5	1.1
Medication: Co-codamol	0.6	0.6	2.4	-1.6	1.3	-0.2	0.3	0.2	0.5	0.3	-0.1	0.0	1.0	0.6	1.4	0.7	0.7	0.9	1.0	0.7	0.4
Trunk fat percentage	0.6	2.3	8.8	1.0	-1.9	0.8	-2.3	-0.7	0.1	-3.0	0.7	-2.0	-2.2	-0.5	0.4	-2.1	-0.0	-0.7	-2.1	-0.1	-1.2
Age when periods started (menarche)	0.6	1.5	7.2	1.6	-0.6	-1.6	-1.4	-0.9	-0.0	-2.1	-0.4	-0.3	-1.2	-0.6	-0.8	-1.0	-1.2	-0.6	-1.0	2.7	0.6
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	1.9	-0.8	0.6	0.8	0.4	1.1	1.4	0.5	-0.3	0.9	0.5	1.3	0.9	0.7	0.7	0.5	0.8	-0.6	0.0
Hayfever, allergic rhinitis or eczema	0.6	1.3	2.9	0.6	1.0	-1.0	-1.5	-1.2	-0.3	-0.6	0.6	-1.6	-0.9	-1.6	-1.7	-1.0	-1.2	-1.6	-1.0	-0.9	-0.8
Number of incorrect matches in round	0.6	1.0	4.0	2.0	0.2	-0.7	0.3	-1.2	-0.2	-1.1	1.1	-0.6	-1.2	-1.0	-0.0	-1.3	-1.4	-1.3	-0.9	1.1	-0.6
Alcohol usually taken with meals	0.6	1.0	2.9	-1.0	-1.7	0.6	0.6	0.7	-1.6	-0.4	-1.2	0.9	0.0	0.8	0.7	0.7	1.2	1.1	0.7	1.2	1.3
Father’s age at death	0.6	0.8	2.3	0.2	0.2	0.5	-1.1	-0.4	-0.4	-1.5	-0.3	-1.2	-1.0	-0.7	0.1	-0.8	-0.3	-1.2	-0.7	-1.5	-1.2
Mouth/teeth dental problems: Dentures	0.6	1.1	3.6	-1.2	0.7	-0.2	1.9	0.9	0.3	1.4	0.3	0.8	1.1	1.2	0.5	1.5	0.8	0.9	1.7	0.9	0.6
Asthma	0.6	1.2	3.9	1.2	-1.2	-2.0	-1.3	-1.2	-0.9	-0.7	0.8	-0.8	-1.3	-0.1	-1.2	-1.2	-1.2	-1.3	-1.1	0.5	-0.3
Length of working week for main job	0.6	0.7	1.8	1.4	-1.0	-1.3	0.6	-0.1	1.3	-0.2	1.2	-0.7	-1.1	0.9	0.0	-0.6	-0.4	-0.1	-0.4	0.6	-0.4
Breastfed as a baby	0.6	0.7	4.5	0.5	0.1	0.8	-1.5	-0.1	-0.1	-2.1	-1.1	0.2	-1.0	-0.8	-0.5	-1.1	-0.7	-0.6	-0.7	0.3	0.2
High blood pressure (siblings)	0.6	0.8	2.8	-0.9	-0.3	0.7	0.6	0.5	0.9	-0.1	1.7	1.5	0.1	0.9	1.1	0.9	0.5	0.7	0.8	0.9	1.3
Number of children fathered	0.6	0.6	2.1	-1.0	0.6	0.1	0.8	1.1	0.3	0.5	0.5	1.0	0.9	1.0	0.9	0.8	0.0	0.3	0.8	0.7	1.4
Medication: Ibuprofen	0.6	0.7	4.5	-0.1	-2.1	0.7	1.2	0.0	0.7	0.8	0.8	0.8	0.4	0.7	0.3	0.7	0.4	1.3	0.6	0.4	0.7
Suffer from ‘nerves’	0.6	0.9	3.0	0.3	-0.8	-1.2	-1.3	-1.3	-0.2	-0.5	0.2	-1.7	-1.0	-1.4	-1.0	-0.5	-0.7	-0.7	-0.8	-0.7	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	3.8	-0.4	0.7	1.9	0.6	0.7	0.2	0.9	0.8	0.8	0.1	1.0	0.6	0.3	0.5	0.3	0.4	0.4	1.3
Asthma (self-reported)	0.6	1.1	4.9	1.0	-0.7	-2.2	-1.2	-1.2	-1.1	-0.7	0.5	-0.7	-1.2	0.1	-1.2	-1.0	-1.3	-1.4	-0.9	0.6	-0.2
Eye problems/disorders: Glaucoma	0.6	0.7	3.9	0.2	0.0	0.8	-1.0	-0.7	-1.2	-1.0	-1.6	-0.5	0.1	-0.4	-2.0	-0.7	-0.9	-0.6	-0.3	-0.1	-0.0
Supplements: Fish oil (including cod liver oil)	0.6	0.8	2.4	0.2	0.6	-0.8	-1.2	-0.8	-0.8	-1.0	-0.0	-1.4	-0.8	-0.9	-0.8	-0.7	-1.1	-1.5	-0.6	-0.9	-0.9
Fractured/broken bones in last 5 years	0.6	0.8	3.5	0.4	1.8	-0.5	0.7	0.2	0.9	0.5	0.9	1.1	-0.3	-0.5	0.1	0.2	-0.2	0.2	-0.2	1.6	1.9
Vascular/heart problems diagnosed by doctor	0.6	1.5	7.7	1.0	-0.8	1.8	-0.8	-0.1	-2.8	-0.3	-2.4	-0.9	-0.6	-0.6	-0.7	-1.3	0.4	0.2	-1.5	-1.1	-1.0
Alzheimer’s Disease (in father)	0.5	0.5	2.2	0.3	-0.3	1.5	0.5	-0.3	-0.9	1.0	-1.1	-0.4	-0.3	0.0	-0.2	0.2	0.2	1.3	0.3	1.0	0.6
Irritable Bowel Disease (IBD)	0.5	1.3	4.0	1.7	0.0	-0.4	-0.5	-0.7	-1.3	-0.4	0.0	-1.6	-1.5	-0.6	-0.9	-1.8	-1.0	-0.9	-2.0	-1.1	-1.0
Body Mass Index (BMI) (2010)	0.5	0.7	2.2	-0.9	0.6	1.5	0.4	0.8	1.2	0.6	0.4	0.8	1.2	1.2	0.5	0.6	1.1	1.0	0.8	0.4	-0.0
HbA1C	0.5	0.6	2.4	-0.7	-0.5	-1.5	0.5	0.3	-1.5	-0.1	-1.0	-0.1	0.3	0.8	-0.4	0.8	0.7	1.2	0.4	-0.1	-0.3
Lupus	0.5	0.7	3.8	-0.5	0.3	-1.4	0.2	-0.1	-0.8	0.3	1.4	0.1	0.3	0.1	0.7	0.2	-0.1	-1.0	0.0	-1.9	-1.6
Chronotype (morning person)	0.5	1.2	3.7	1.6	0.5	-1.5	0.2	-1.3	-0.9	-0.7	-0.8	-1.5	-1.2	-0.8	-1.4	-0.9	-1.9	-0.8	-1.1	-0.2	0.3
Sensitivity / hurt feelings	0.5	0.8	3.5	-1.0	0.8	1.6	0.3	0.5	0.0	0.1	1.9	0.5	0.5	1.2	0.5	0.8	0.6	0.2	0.8	1.0	1.2
Diabetes (father)	0.5	0.6	2.3	0.3	1.5	-1.1	-1.0	-0.7	0.1	-1.3	0.5	0.1	-0.6	-0.4	-0.8	-0.7	-1.0	-0.9	-0.8	0.3	-0.0
High blood pressure	0.5	1.3	6.7	-1.0	0.8	-1.4	0.5	0.1	2.6	-0.1	2.5	0.6	0.4	0.7	0.7	0.9	-0.4	-0.5	1.2	1.1	0.8
Had other major operations	0.5	0.6	3.1	-0.8	1.8	-0.2	-0.3	0.1	0.9	0.8	0.1	-0.8	0.8	0.1	-0.8	0.6	0.2	0.3	0.7	0.5	1.3
Diabetes (self-reported)	0.5	0.7	8.7	1.0	-0.6	-2.9	-0.4	-1.0	0.4	-0.0	0.2	0.1	-0.8	0.2	0.2	-0.5	-0.4	-0.2	-0.5	0.7	-0.5
Impedance of arm (left)	0.5	2.5	7.4	1.0	-0.6	-1.0	-1.8	-0.6	-1.0	-2.4	-2.5	-2.7	-1.9	-0.6	-1.1	-2.1	-0.7	-1.1	-2.3	-1.0	-0.2
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	2.1	-0.5	1.2	1.2	1.3	1.4	-0.2	1.0	0.5	0.9	1.2	0.6	0.4	0.7	0.6	0.6	0.5	-0.4	1.0
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	7.8	-0.0	1.6	0.8	0.1	0.3	2.8	-0.3	1.6	0.6	-0.4	1.0	0.6	0.2	0.5	0.5	0.3	1.2	0.8
Number of full brothers	0.5	0.6	3.5	0.5	-1.9	0.8	-0.8	-0.7	0.1	-0.1	0.6	-0.6	-0.7	-0.3	-0.5	-0.7	-0.6	-0.7	-0.6	-0.6	-1.1
Health satisfaction	0.5	0.6	5.0	0.2	2.2	-0.4	-0.9	-0.6	0.1	-0.3	-0.6	-1.1	-0.3	-0.3	-0.9	-0.7	-1.0	-0.6	-0.5	-0.2	0.6
Leg pain on walking	0.5	0.6	2.4	0.4	0.8	0.1	-0.9	-0.5	-0.6	-1.6	0.1	-0.5	-1.1	-0.2	-0.3	-0.8	-0.8	-1.4	-0.7	-0.7	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	3.8	-0.6	1.1	2.0	0.0	0.5	1.1	0.3	0.5	0.5	1.1	0.2	0.8	0.4	0.2	0.4	0.9	-0.7	-0.0
Qualifications: nursing, teaching	0.5	0.7	5.0	-0.0	2.2	-1.9	0.5	0.3	0.6	0.4	0.2	0.8	0.2	-0.2	-1.0	-0.1	-0.7	-0.7	-0.5	-0.2	0.5
Medication: Bendroflumethiazide	0.5	0.8	4.2	0.6	0.6	-2.1	-0.2	-0.6	0.6	-0.9	1.5	0.3	-0.6	-1.0	0.4	-0.4	-0.8	-1.2	-0.8	0.7	0.8
Medication: Lisinopril	0.5	0.7	3.1	-0.5	-1.2	-1.7	0.3	-0.0	-0.2	-0.2	0.9	0.1	0.2	0.4	1.5	0.1	0.5	0.1	0.3	-0.7	-1.8
Reaction Time	0.4	0.7	4.7	0.9	-0.2	2.2	-0.9	-0.8	0.6	-0.3	0.1	-1.3	-0.1	-0.6	-0.9	-0.8	0.0	-0.0	-0.5	0.5	-1.1
Ovarian Cancer	0.4	0.5	2.5	-0.2	-0.2	0.1	-0.6	-0.6	-1.3	-0.2	-0.5	-1.1	-1.1	-0.3	-0.9	-0.6	-0.2	-0.1	-0.9	-1.6	-0.1
Age at First Birth	0.4	0.6	2.1	1.2	-1.3	-0.1	-0.4	-1.5	-0.6	0.1	-0.2	-0.9	-0.9	-0.2	-1.2	-1.0	-0.2	-0.2	-0.7	0.5	-0.7
Bipolar Disorder (2011)	0.4	0.4	2.0	-0.8	0.2	0.8	-0.5	0.5	0.3	0.6	0.6	0.2	0.8	-0.0	0.2	0.6	0.9	1.4	0.6	0.0	0.6
Crohns Disease (2012)	0.4	0.6	2.7	0.9	-1.3	0.4	-0.4	0.3	-0.7	-0.6	1.0	-0.6	-1.0	-0.2	0.3	-1.4	0.2	-0.1	-1.6	-0.3	-0.2
Cardiovascular Disease	0.4	1.2	8.4	-0.7	-0.1	-0.6	0.5	0.2	2.7	0.2	2.9	0.8	0.1	1.1	0.1	1.0	0.0	0.2	1.2	0.7	-0.1
Hypothyroidism (self reported)	0.4	0.9	4.3	0.6	1.6	1.1	0.0	0.0	2.1	-0.7	1.0	0.5	-0.7	1.1	-0.2	-0.2	-0.1	0.3	-0.1	1.8	1.3
Average weekly spirits intake	0.4	0.5	3.7	-0.7	0.9	1.1	0.4	0.1	-0.6	0.3	1.9	0.5	0.1	0.3	0.4	0.5	0.3	0.2	0.7	-0.1	0.3
Vitamin and mineral supplements	0.4	0.5	2.2	-0.1	0.8	0.5	0.5	0.3	0.6	0.3	-1.5	0.7	1.4	0.3	0.2	0.6	0.6	0.6	0.8	1.1	0.4
Supplements: Zinc	0.4	0.5	2.4	-0.0	1.5	-0.0	-0.3	0.1	-0.0	-0.1	-0.5	-0.4	-0.9	-0.0	-0.2	-0.5	-0.5	-1.5	-0.9	-1.0	0.3
Average weekly fortified wine intake	0.4	0.5	1.6	-1.0	0.3	0.6	0.2	1.3	1.1	0.3	-0.1	0.1	1.0	0.9	0.5	0.5	1.2	0.7	0.5	0.3	-0.2
Relative age voice broke	0.4	0.5	2.9	0.8	-0.8	0.2	0.0	-0.9	-0.5	0.8	1.7	1.1	-0.7	-0.9	-0.3	-0.5	-0.5	-0.4	-0.7	-0.0	-0.4
Taking other prescription medications	0.4	0.6	3.5	-0.6	1.0	-1.1	0.4	0.2	1.4	0.3	0.4	0.1	-0.5	0.8	1.9	0.5	0.4	0.2	0.4	0.4	1.0
Supplements: Glucosamine	0.4	0.5	4.9	0.4	0.1	0.6	-0.4	0.1	0.9	-0.1	2.2	-0.0	-0.4	0.4	0.6	-0.3	0.2	-0.1	-0.2	1.4	-0.5
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	1.8	-0.9	0.5	-0.1	1.0	0.4	-0.7	1.4	0.2	0.3	0.3	0.8	-0.0	1.0	0.5	0.7	0.6	0.7	-0.0
Pulse rate	0.4	0.7	2.0	1.3	-0.1	1.4	-0.6	0.1	0.6	-0.3	0.9	-0.1	-0.4	-1.1	-0.4	-1.2	-0.1	-0.9	-1.3	-1.1	-0.3
Qualifications: A levels/AS levels or equivalent	0.4	1.0	2.9	-0.6	0.9	-0.2	1.3	1.1	1.3	1.2	1.7	1.4	0.6	1.4	0.5	0.8	0.4	0.4	0.6	0.8	0.7
Medication: Cholesterol lowering	0.4	0.6	2.6	-0.2	0.5	-1.6	0.8	0.1	1.4	1.1	1.3	0.4	-0.0	0.3	0.5	0.7	-0.5	-0.3	0.6	0.0	0.2
Depression (self-reported)	0.4	0.5	3.0	-0.9	-0.9	0.4	0.0	0.1	0.5	0.5	-0.1	0.2	0.4	0.6	1.7	0.7	0.3	0.6	0.6	1.1	0.9
Exposure to tobacco smoke at home	0.4	0.4	1.8	-0.1	0.0	-0.3	1.0	0.5	0.1	1.3	-0.6	-0.2	-0.1	0.3	0.3	0.3	0.4	1.2	0.5	0.5	1.1
Medication: Paracetamol	0.4	0.7	3.6	-0.1	-1.0	1.1	1.0	0.5	0.2	1.3	0.6	0.5	1.9	-0.4	0.7	0.2	1.0	0.3	0.7	0.4	-1.1
Leg fat percentage (right)	0.4	1.4	7.3	-1.0	-0.7	1.1	0.4	0.9	1.5	-0.0	2.7	0.7	0.2	1.1	2.3	0.5	1.5	0.8	0.5	1.0	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	2.3	-0.9	1.5	-0.4	0.2	0.9	1.1	0.3	0.6	0.1	0.6	0.5	0.8	0.6	0.3	0.2	0.4	0.6	1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	2.9	-0.1	0.7	-1.4	-0.2	0.6	0.2	-0.9	-1.7	-0.6	0.2	-0.4	0.2	-0.3	-0.1	-0.5	0.0	-0.9	0.4
Eye problems/disorders: None of the above	0.4	0.4	2.7	0.2	-0.3	-0.4	-0.7	0.4	1.6	0.4	1.3	0.3	-0.5	-0.4	0.1	-0.1	0.2	0.2	-0.3	0.9	0.7
Neck or shoulder pain in last month	0.4	0.5	3.2	-0.1	1.2	-1.8	1.0	-0.3	0.0	0.7	-0.2	0.1	-0.6	0.6	0.2	0.5	-0.8	-0.6	0.3	0.1	1.0
Mean time to correctly identify matches	0.4	0.8	2.7	1.5	-0.1	1.2	-0.8	-1.1	0.2	-0.6	-0.5	-1.7	-0.4	-1.1	-1.0	-1.2	-0.6	-0.6	-0.7	0.5	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	2.6	0.4	-0.2	-0.7	-0.7	-0.2	-1.0	-0.5	-1.6	-0.4	-0.3	-1.3	-0.3	-0.4	-0.8	-0.7	-0.7	-0.5	-0.3
Leg fat mass (right)	0.4	1.4	4.6	0.6	-2.2	0.6	-1.6	-0.6	-0.1	-1.6	1.5	-1.1	-1.6	-0.3	0.7	-1.3	-0.0	-0.5	-1.3	-0.3	-1.8
Number of full sisters	0.4	0.4	2.7	0.0	1.6	-0.2	0.4	-0.2	-0.9	0.7	-0.7	-0.2	0.2	-0.8	-1.1	0.1	-0.6	-0.3	0.4	-1.0	-0.2
Supplements: Vitamin C	0.4	0.5	1.3	1.0	0.4	-0.1	0.2	-0.8	0.4	-0.0	0.3	-0.8	-0.3	-0.6	-1.0	-0.8	-1.1	-0.8	-0.6	0.9	0.5
Hypertension (Self-reported)	0.4	1.0	5.2	-0.9	0.6	-1.4	0.5	0.1	2.3	-0.0	2.2	0.5	0.3	0.4	0.6	0.8	-0.3	-0.3	1.0	1.3	0.8
Average weekly red wine intake	0.4	0.5	3.4	-1.0	-0.6	0.4	0.2	0.8	-0.9	0.6	-1.9	-0.3	0.7	0.7	0.2	0.5	0.5	0.1	0.6	-0.7	0.1
Loneliness, isolation	0.4	0.6	1.8	-1.3	0.8	0.2	1.0	1.0	-1.0	0.2	0.1	0.3	0.7	1.0	0.4	0.7	0.9	0.3	0.5	0.0	1.1
Diabetes diagnosed by doctor	0.4	0.7	4.8	0.1	-0.3	-2.2	0.9	-0.1	0.8	1.2	0.2	1.2	0.5	1.0	0.9	0.5	0.2	0.5	0.6	0.9	0.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	5.7	-0.2	-0.3	0.7	0.1	0.4	-0.6	-0.6	-2.4	-1.0	-0.6	0.9	0.1	-0.1	-0.2	0.1	-0.1	-0.8	-0.3
Illnesses of father: None of the above (group 1)	0.4	0.6	4.0	0.8	-2.0	-0.1	-1.0	-0.3	-0.0	-0.8	-0.0	-0.6	-0.1	-0.7	-0.3	-0.9	-0.7	-0.8	-0.6	-0.0	-0.6
Ever taken oral contraceptive pill	0.4	0.4	2.5	-0.8	0.4	0.9	0.2	0.6	-1.6	0.6	-0.3	0.1	0.8	-0.6	0.1	0.3	0.0	0.6	0.5	-0.7	0.6
Mother’s age at death	0.4	0.5	2.1	-1.0	1.3	-0.6	0.1	0.5	0.6	1.0	0.0	0.4	0.5	-0.1	0.5	0.5	-0.1	-0.4	0.3	-0.8	1.4
Tinnitus: Yes, now most or all of the time	0.4	0.4	1.8	0.3	0.2	-1.3	0.3	-0.4	-0.8	0.1	1.1	0.0	0.0	-0.1	-0.9	-0.2	-0.8	-0.6	-0.0	-1.2	-0.5
High cholesterol (Self-reported)	0.4	0.8	6.0	0.8	-0.4	-2.5	-0.0	-0.9	0.2	-0.3	1.5	0.5	-0.5	-0.2	-0.1	-0.3	-1.0	-0.6	-0.1	-0.5	-1.4
Medication: Paracetamol	0.4	0.6	2.9	0.1	-1.3	1.0	1.1	0.1	-0.0	1.1	0.6	0.6	1.7	-0.3	0.5	0.2	0.7	0.5	0.6	0.4	-1.0
Basal cell carcinoma (self-reported)	0.4	0.5	1.4	0.1	-0.5	0.2	1.1	0.2	1.1	1.1	-0.3	0.3	0.2	0.8	1.2	0.8	-0.0	0.7	0.8	1.1	0.6
Leg fat mass (left)	0.4	1.6	5.0	0.8	-2.2	0.4	-1.8	-0.9	-0.3	-1.9	1.3	-1.4	-1.7	-0.4	0.3	-1.5	-0.3	-0.8	-1.5	-0.4	-1.9
Schizophrenia (2018)	0.3	0.7	2.3	0.9	-1.5	-0.2	-0.6	-0.8	-1.4	-0.6	-0.8	-0.6	-0.9	0.0	-0.6	-0.8	-0.4	-0.4	-0.9	0.3	-1.4
Schizophrenia vs Biploar Disorder	0.3	0.4	2.3	0.4	-0.4	-0.5	-0.2	-0.1	-1.0	-0.7	-0.5	-0.6	0.0	-0.2	0.2	-0.3	-0.0	-0.5	-0.1	-1.5	-1.5
Alzheimer’s Disease (including proxy)	0.3	0.4	1.1	-0.2	0.3	-0.2	0.6	0.1	-0.6	0.6	-0.7	0.7	0.8	0.5	0.1	1.0	0.2	0.8	1.0	1.1	0.8
Coronary Artery Disease (CAD)	0.3	0.4	1.6	-0.8	1.0	1.3	-0.2	0.9	0.5	-0.2	-0.5	0.5	1.1	-0.1	0.4	0.4	0.4	0.3	0.8	-0.3	0.4
Blood White Count	0.3	2.0	5.0	-1.6	-0.0	1.0	1.4	-0.1	0.9	1.6	1.4	2.2	1.4	0.8	0.2	2.0	0.3	1.5	2.2	2.2	1.2
Respiratory disease	0.3	0.7	1.7	0.6	0.2	-1.2	-1.3	-0.6	-1.0	-1.0	-0.3	-0.6	-1.1	-0.4	-1.0	-1.0	-0.8	-1.2	-1.2	0.3	0.1
Lung FEV1/FVC ratio	0.3	1.4	6.2	-0.4	1.4	-2.5	1.6	1.0	0.3	-0.0	-1.1	1.0	1.2	0.8	1.1	1.0	-0.1	0.4	0.7	1.6	1.6
Neuroticism	0.3	0.6	1.8	-1.3	1.0	-0.8	0.4	1.0	0.5	0.2	1.0	0.6	0.6	0.9	1.1	0.8	0.6	-0.7	0.7	-0.0	1.2
Number of treatments/medications taken	0.3	0.5	3.0	0.2	1.0	-1.7	-0.0	-0.5	1.0	0.1	0.7	-0.7	-0.6	-0.1	0.9	-0.3	-0.6	-0.6	-0.3	-0.6	0.2
Ever had hysterectomy (womb removed)	0.3	0.3	1.0	-0.5	0.6	1.0	-0.3	-0.4	0.6	0.1	-0.9	0.1	0.4	-0.2	0.6	0.4	0.1	1.0	0.3	0.6	0.9
Diabetes (mother)	0.3	0.4	1.7	0.8	-0.1	-0.1	-0.1	0.3	1.3	0.3	-0.1	-0.3	-0.4	0.4	0.5	-0.2	0.6	1.2	-0.2	1.0	0.5
Multivitamins +/- minerals	0.3	0.3	1.2	-0.1	-0.4	-0.2	-0.5	-0.1	-0.5	0.0	1.0	-0.3	-1.1	-0.1	-0.2	-0.5	-0.3	-0.6	-1.0	-1.1	-0.4
Qualifications: None of the above	0.3	0.7	2.4	0.5	-0.8	-1.0	-1.0	-1.0	0.3	-0.9	0.7	-1.0	-1.0	-1.3	-0.5	-0.6	-0.6	-0.6	-0.5	1.5	-0.5
Medication: Simvastatin	0.3	0.5	4.1	0.2	-0.8	-2.0	0.1	-0.4	1.0	-0.3	0.8	0.2	-0.6	0.2	0.4	0.4	-0.2	0.0	0.2	-0.4	-0.7
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	1.7	0.0	-1.3	0.5	0.8	-0.1	0.6	0.4	0.7	0.7	0.2	0.4	-0.3	0.3	-0.2	0.7	0.2	0.6	1.0
Arm fat mass (right)	0.3	1.3	4.6	-0.0	-2.1	2.1	-1.4	0.0	0.5	-1.6	1.4	-1.1	-1.1	0.3	1.1	-0.9	0.9	0.5	-0.8	0.3	-1.5
Tense / ‘highly strung’	0.3	0.6	1.7	-0.9	0.1	-0.7	0.8	0.7	0.3	1.2	1.3	0.6	0.3	1.1	0.9	0.7	-0.1	-0.3	0.3	0.1	1.0
Hair/balding pattern: Pattern 4	0.3	0.7	3.1	-0.3	-0.3	-0.9	-1.5	-0.9	-1.2	-1.3	0.3	-0.5	-0.6	-0.8	-1.8	-0.4	-0.1	0.0	-0.5	-0.6	0.5
Glaucoma (self-reported)	0.3	0.3	1.0	-0.3	0.5	0.9	-0.8	0.4	0.6	-1.0	-0.7	-0.5	0.7	0.5	-0.3	-0.2	0.3	0.0	0.4	0.6	0.1
Gout (self-reported)	0.3	0.4	2.5	0.3	-1.4	0.4	-0.8	-0.3	0.5	-0.3	-1.6	-0.9	-0.5	-0.2	0.7	-0.3	-0.2	0.5	-0.2	0.1	-0.1
Medication: Amlodipine	0.3	0.5	2.6	-0.4	1.0	-1.6	-0.0	0.2	1.2	0.1	0.4	0.1	0.4	0.2	0.5	0.4	0.0	0.3	0.3	1.1	1.1
Body fat percentage	0.3	1.0	3.1	0.0	-1.6	1.3	-1.2	0.1	0.7	-1.8	1.5	-0.8	-1.1	0.3	1.3	-0.9	0.9	0.2	-0.9	0.5	-0.7
Medication: Allopurinol	0.3	0.4	1.6	-0.2	-0.9	0.3	0.1	-0.1	1.2	0.1	0.2	0.3	0.0	0.1	1.2	0.3	0.5	1.1	0.1	1.3	0.2
Family relationship satisfaction	0.3	0.4	2.1	-0.0	0.5	-0.4	-0.9	-0.6	-0.9	-0.6	0.1	0.2	-0.3	-0.6	-1.4	-0.3	-1.0	-0.4	-0.4	-0.1	0.8
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	1.2	0.5	-0.4	1.1	-0.3	-0.5	0.8	-0.3	0.8	0.5	-0.9	-0.4	-0.6	-0.4	0.0	-0.2	-0.3	0.1	-0.5
Smoking status: Previous	0.3	0.5	1.8	0.1	-0.2	-0.4	-0.6	-0.5	-1.3	-1.0	-0.5	-0.2	-0.5	-0.5	-0.3	-0.7	-1.0	-1.2	-0.7	0.0	0.6
Handedness (chirality/laterality): Left-handed	0.3	0.4	2.8	0.4	-0.6	0.1	-0.5	0.4	-1.7	-0.1	-0.2	-0.7	0.1	-0.5	-0.4	-0.5	0.6	-0.0	-0.5	-0.5	-1.0
Friendships satisfaction	0.3	0.3	2.2	-0.4	0.3	1.3	0.4	0.4	0.0	0.7	0.5	1.5	0.5	0.1	-0.5	0.3	0.1	0.3	0.5	0.4	0.1
Commuting to job workplace: Walk	0.3	0.3	1.7	0.2	1.3	-0.1	-0.4	-0.1	0.0	-0.5	1.3	0.3	-0.2	-0.4	0.5	-0.1	-0.0	-0.3	-0.2	-0.8	-0.5
Eye problems/disorders: Cataract	0.3	0.3	1.0	-0.2	0.9	0.9	0.9	-0.2	0.7	0.2	-0.0	-0.3	1.0	0.5	0.4	0.5	0.2	0.3	0.6	0.6	-0.1
Arm fat mass (left)	0.3	1.3	4.8	-0.1	-2.2	2.2	-1.5	0.0	0.4	-1.6	1.1	-1.0	-1.0	0.2	1.0	-0.8	0.9	0.6	-0.8	0.3	-1.6
Number of self-reported non-cancer illnesses	0.3	0.6	4.5	-0.4	0.5	-2.1	-1.0	-1.0	0.3	-0.4	-0.4	-0.5	-0.3	0.0	-0.1	-0.0	-1.3	-0.7	0.5	0.3	0.4
Alcohol drinker status: Never	0.3	0.3	1.7	-0.4	-0.1	-1.3	0.5	-0.1	-0.3	0.1	0.1	0.8	-0.2	0.4	0.8	0.4	0.7	0.4	0.5	0.8	0.0
Number of operations (self-reported)	0.3	0.5	1.8	-1.1	-0.4	-0.0	0.0	-0.4	0.8	1.0	0.8	0.3	0.1	0.4	0.8	1.3	0.1	0.6	1.3	0.3	0.2
Ever had prostate specific antigen (PSA) test	0.3	0.4	2.1	-0.7	0.7	0.8	-0.1	0.1	-0.5	0.0	-1.4	0.0	0.0	-0.3	0.0	0.3	-0.7	-0.3	0.2	0.2	1.3
Supplements: Calcium	0.3	0.3	1.9	-0.1	1.3	0.4	0.2	-0.1	-0.1	-0.1	0.6	0.3	-0.5	-0.1	-0.5	-0.3	0.1	-0.6	-0.5	-1.4	0.2
Alcohol drinker status: Previous	0.3	0.4	2.6	-0.1	0.1	-0.1	-0.1	0.4	-0.4	-0.1	-1.6	0.2	1.1	-0.1	-0.7	-0.1	-0.4	-0.8	0.3	0.2	0.9
Bipolar Disorder or Schizophrenia	0.2	0.4	2.5	-0.5	0.3	0.5	0.1	0.2	-0.0	0.9	-0.0	0.3	0.2	1.2	0.2	0.7	0.7	1.1	0.6	1.6	0.3
Worry (Nagel 2018)	0.2	0.3	1.0	-0.8	0.3	-0.9	0.3	0.6	0.4	0.6	1.0	-0.1	-0.2	0.3	1.0	0.3	0.3	-0.6	-0.1	-0.5	0.6
Ulcerative Colitis (UC)	0.2	0.5	1.3	0.8	1.0	-0.0	-0.1	-0.5	-0.7	0.2	-0.5	-1.1	-1.0	-0.0	-0.6	-0.7	-0.7	-0.5	-1.1	-0.6	-0.4
HDL Cholesterol	0.2	0.3	1.7	0.5	-1.3	1.3	0.8	0.4	-0.3	-0.3	0.2	-0.1	0.3	0.6	-0.4	-0.1	-0.1	0.3	-0.2	-0.4	-0.1
Neuroticism (2016)	0.2	0.4	2.5	0.7	-0.3	-1.6	-0.1	-0.3	0.7	-0.2	0.7	-1.1	-0.3	-0.3	-0.4	-0.2	-0.4	-0.4	-0.2	0.2	-0.3
Blood Eosinophil Count	0.2	1.8	4.4	-1.7	-0.8	-0.3	0.8	0.9	0.8	1.6	2.1	1.4	1.7	1.8	1.1	1.1	1.4	1.7	1.1	1.9	0.7
Blood Red Count	0.2	1.7	5.4	1.0	-0.1	-0.4	-2.0	-1.6	-0.2	-2.3	-1.4	-0.7	-1.0	-1.2	-1.2	-1.0	-1.4	-1.7	-0.8	-0.9	-1.8
Systolic Blood Pressure	0.2	0.9	10.7	-0.1	0.4	-3.3	0.0	-0.5	-0.7	-0.5	0.3	0.0	-0.5	-0.8	-0.5	-0.2	-1.0	-0.9	-0.6	-1.0	0.1
Type 2 Diabetes (T2D) (2018)	0.2	0.4	4.5	0.7	-0.4	-2.1	-0.1	-0.6	-0.2	0.8	0.3	0.8	0.0	-0.1	-0.4	-0.2	-0.4	0.0	-0.1	0.1	-0.2
Pack years adult smoking proportion	0.2	0.3	1.7	0.2	0.4	0.5	0.2	-0.1	1.3	0.5	0.5	-0.3	0.7	0.3	-0.3	0.2	0.3	0.5	0.7	-0.7	-1.1
Chronic bronchitis/emphysema (father)	0.2	0.3	1.2	-0.1	-0.4	-1.1	-0.7	-0.8	-0.8	-0.1	-0.5	-0.4	-0.9	-0.2	-0.3	-0.3	-0.3	-0.4	-0.5	-0.1	-0.2
Nervous feelings	0.2	0.3	2.9	-0.5	0.3	-1.7	-0.1	-0.2	0.1	0.1	0.8	-0.5	-0.3	0.4	0.3	0.3	-0.3	-0.5	-0.1	-0.1	0.1
Worrier / anxious feelings	0.2	0.3	2.2	0.2	1.1	-0.3	0.7	0.1	0.1	0.1	0.4	0.1	-1.0	-0.5	0.2	0.1	-0.2	-0.4	-0.4	-0.1	1.5
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	1.1	-0.5	-0.1	-1.0	-0.1	0.0	-1.1	-0.2	-0.5	0.2	0.6	0.4	0.4	0.1	0.1	-0.3	0.4	-0.3	-0.4
Qualifications: College or University degree	0.2	0.7	3.0	-0.8	0.1	0.9	0.5	0.9	0.4	0.9	1.1	1.7	0.9	0.9	0.5	0.6	0.6	0.1	0.6	0.5	1.0
Emphysema/chronic bronchitis	0.2	0.2	0.7	0.2	-0.4	0.6	0.4	0.4	-0.4	0.0	-0.8	-0.7	-0.7	0.8	0.6	-0.2	0.2	0.0	-0.1	0.2	-0.2
Hearing aid user	0.2	0.2	0.8	-0.2	-0.5	-0.3	0.5	-0.1	-0.3	0.6	0.5	0.4	0.1	-0.1	-0.1	0.3	0.8	0.8	0.4	0.9	-0.3
Ever smoked	0.2	0.3	2.7	-0.7	0.5	1.6	0.1	0.8	-0.2	0.1	0.3	-0.1	-0.1	0.1	-0.1	-0.0	-0.0	-0.5	0.1	-0.9	-0.1
Leg fat percentage (left)	0.2	0.9	5.7	-0.7	-0.7	0.8	0.2	0.6	1.2	-0.3	2.4	0.4	0.1	1.1	1.6	0.3	1.1	0.4	0.3	0.9	-0.1
Unable to work because of sickness or disability	0.2	0.3	2.0	-0.3	1.4	0.1	0.6	0.6	0.1	0.6	-0.7	-0.1	0.6	-0.0	0.5	0.3	0.2	0.4	0.4	-0.3	0.2
Commuting to job workplace: Cycle	0.2	0.2	0.8	0.3	0.4	0.4	0.7	0.3	0.7	0.6	0.6	0.0	0.2	0.4	0.9	-0.3	0.5	-0.2	-0.2	-0.0	-0.2
Pack years of smoking	0.2	0.3	2.5	0.3	0.0	0.3	0.1	-0.4	1.1	0.3	0.5	-0.3	0.5	0.1	-0.0	0.0	0.1	0.2	0.6	-1.0	-1.6
Intelligence (Savage-Jansen 2018)	0.1	0.4	2.8	-0.0	-0.4	1.7	0.1	0.0	-0.3	0.3	0.9	1.0	-0.7	0.3	-0.2	0.1	-0.1	-0.2	-0.3	-0.0	-0.8
Rheumatoid Arthritis	0.1	0.1	0.3	0.1	-0.4	-0.0	-0.5	-0.4	-0.4	-0.3	-0.4	-0.4	0.1	0.5	-0.0	-0.3	-0.1	0.1	-0.1	-0.1	0.2
Schizophrenia (2014)	0.1	0.2	1.2	0.5	-0.1	-0.4	0.5	-0.1	-1.1	0.6	-0.5	-0.3	-0.0	0.7	-0.3	0.0	0.0	-0.0	0.1	0.5	-0.9
Blood Platelet Count	0.1	0.9	4.2	-0.4	1.4	0.1	0.5	0.1	-2.1	0.2	-1.4	0.2	-0.2	0.4	-1.3	0.3	0.0	-0.1	-0.3	1.6	1.9
Hair Pigment	0.1	1.6	4.8	-0.1	-1.0	-2.2	-1.3	-1.2	-1.8	-0.8	-1.3	-1.3	-0.4	-0.2	-0.4	-1.0	-1.3	-1.7	-1.2	-1.9	-1.2
Tanning	0.1	1.0	2.8	-0.6	-0.3	1.3	0.9	0.8	1.1	0.6	0.7	1.1	-0.0	0.9	0.4	0.9	1.1	1.5	0.8	1.5	1.7
Systolic blood pressure, automated reading	0.1	0.3	3.6	-0.5	0.4	-1.9	0.7	0.0	0.3	-0.2	0.5	-0.1	0.3	0.3	0.7	0.4	-0.0	-0.2	0.2	-0.6	-0.1
Stomach or abdominal pain in last month	0.1	0.2	0.5	0.5	-0.7	-0.3	-0.4	0.0	-0.2	0.5	-0.0	-0.5	0.2	-0.3	0.4	-0.5	-0.1	-0.4	-0.4	-0.4	-0.7
Past tobacco smoking	0.1	0.2	1.0	0.8	-0.6	-0.8	-0.1	-0.5	1.0	0.0	0.4	-0.1	-0.3	-0.1	-0.5	-0.0	0.1	0.5	-0.2	0.2	-0.6
Illnesses of siblings	0.1	0.1	1.6	0.0	-0.2	0.1	0.0	0.5	-0.3	-0.2	-1.3	-0.5	0.0	0.0	0.3	-0.1	0.2	0.0	-0.1	0.1	-0.1
Wheeze or whistling in the chest in last year	0.1	0.1	0.4	-0.2	0.4	-0.6	-0.2	0.2	0.3	0.0	-0.4	-0.5	0.2	0.5	0.1	-0.1	0.1	0.2	0.2	-0.4	0.0
Alcohol intake frequency.	0.1	0.2	0.7	0.3	-0.4	-0.8	-0.1	-0.3	0.6	-0.2	-0.1	-0.8	-0.2	0.3	0.4	-0.3	0.2	-0.6	-0.1	-0.2	-0.7
Diastolic blood pressure, automated reading	0.1	0.3	0.9	0.1	0.4	0.3	-0.2	-0.8	0.6	-0.1	-0.0	-0.7	0.2	-0.8	-0.9	-0.2	-0.9	-0.5	-0.3	-0.4	0.1
Pain experienced in last month	0.1	0.2	0.5	-0.6	0.7	0.0	0.2	0.7	0.0	-0.5	-0.0	0.6	0.7	0.2	0.6	0.4	0.5	-0.1	0.4	-0.7	0.3
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

CCDC91

Models

Trait associations