[Hub]/) : Traits : Whole body fat-free mass : ← →

chr12:101,575,652-103,148,974

Best TWAS P=1.41e-09 · Best GWAS P=1.68e-14 conditioned to 4.36e-09

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
10	YFS	Blood	DRAM1	0.33	0.13	enet	101	0.19	1.6e-58	5.9	6.0	1.4e-09	-0.20	1.00	0.00	TRUE
7	GTEx	Spleen	CCDC53	0.25	0.19	lasso	11	0.16	5.8e-05	5.7	-5.7	9.5e-09	0.14	0.51	0.05	TRUE
9	METSIM	Adipose	DRAM1	0.12	0.03	enet	24	0.08	1.1e-12	4.1	5.9	3.9e-09	-0.10	1.00	0.00	FALSE
15	The Cancer Genome Atlas	Stomach Adenocarcinoma	CCDC53	0.04	0.07	lasso	4	0.06	2.1e-05	5.7	-5.7	1.1e-08	0.13	0.83	0.01	FALSE
3	GTEx	Cells Transformed fibroblasts	CCDC53	0.10	0.18	lasso	1	0.17	1.5e-12	5.7	-5.7	1.2e-08	0.13	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CCDC53	0.21	0.15	blup	448	0.19	2.4e-22	3.9	-5.5	3.0e-08	-0.04	1.00	0.00	FALSE
12	The Cancer Genome Atlas	Esophageal Carcinoma	CCDC53	0.14	0.08	blup	50	0.08	1.8e-03	5.7	-5.4	5.4e-08	0.15	0.14	0.06	FALSE
11	The Cancer Genome Atlas	Colon Adenocarcinoma	CCDC53	0.07	0.07	blup	55	0.06	1.3e-04	4.9	-5.4	7.7e-08	0.18	0.93	0.00	FALSE
5	GTEx	Heart Left Ventricle	CCDC53	0.14	0.20	lasso	4	0.18	9.6e-10	5.7	-5.3	9.0e-08	0.09	1.00	0.00	FALSE
8	GTEx	Thyroid	CCDC53	0.15	0.12	lasso	6	0.12	4.3e-09	5.7	-5.2	1.8e-07	0.09	1.00	0.00	FALSE
4	GTEx	Esophagus Mucosa	CCDC53	0.31	0.41	enet	17	0.43	1.0e-30	4.0	-5.2	1.9e-07	0.04	1.00	0.00	FALSE
6	GTEx	Lung	CCDC53	0.12	0.10	lasso	3	0.11	6.8e-09	5.7	-5.2	1.9e-07	0.10	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	CCDC53	0.14	0.16	lasso	13	0.15	1.5e-12	5.8	-5.2	2.5e-07	0.06	1.00	0.00	FALSE
13	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CCDC53	0.06	0.10	lasso	3	0.10	7.3e-11	5.7	-5.2	2.5e-07	0.06	1.00	0.00	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CCDC53	0.08	0.09	lasso	3	0.09	4.9e-10	5.7	-5.1	2.7e-07	0.09	1.00	0.00	FALSE