Best TWAS P=1.73e-20 · Best GWAS P=4.31e-45 conditioned to 1.37e-23
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Male) | MRPL42 | 0.21 | -0.01 | lasso | 2 | -0.01 | 6.0e-01 | 9.4 | -9.3 | 1.7e-20 | -0.48 | 0.05 | 0.06 | TRUE |
| 2 | GTEx | Muscle Skeletal | MRPL42 | 0.07 | 0.02 | lasso | 3 | 0.04 | 1.5e-04 | -5.4 | -5.5 | 2.9e-08 | -0.17 | 0.69 | 0.01 | TRUE |
| 3 | YFS | Blood | SOCS2 | 0.06 | 0.04 | bslmm | 444 | 0.04 | 1.7e-12 | 6.8 | 8.2 | 2.3e-16 | 0.01 | 1.00 | 0.00 | TRUE |
| 4 | YFS | Blood | UBE2N | 0.02 | 0.00 | bslmm | 424 | 0.01 | 3.6e-03 | 11.9 | 5.4 | 6.2e-08 | 0.38 | 0.06 | 0.26 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | MRPL42 | 0.07 | 0.03 | blup | 49 | 0.03 | 1.4e-04 | -3.2 | 5.3 | 9.4e-08 | 0.21 | 0.26 | 0.58 | FALSE |