TWAS
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Usage
Models
Genes
Traits
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Traits
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Whole body fat-free mass
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chr18:45,873,080-47,686,517
Best TWAS P=4.31e-11 · Best GWAS P=1.56e-15 conditioned to 0.00284
46M
46.5M
47M
47.5M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adrenal Gland
DYM
0.30
0.01
enet
15
0.01
1.2e-01
7.3
6.6
4.3e-11
0.81
0.03
0.82
TRUE
4
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
C18orf32
0.04
0.03
blup
48
0.04
6.5e-05
4.4
6.4
1.1e-10
0.57
0.00
0.99
TRUE
3
YFS
Blood
DYM
0.05
0.05
lasso
4
0.04
1.5e-13
-4.7
6.1
9.7e-10
0.76
1.00
0.00
FALSE
2
GTEx
Esophagus Mucosa
DYM
0.12
0.01
enet
12
0.04
1.0e-03
7.7
5.7
1.4e-08
0.73
0.01
0.96
FALSE