[Hub]/) : Traits : Whole body fat-free mass :

chr2:168,949,234-170,419,444

Best TWAS P=3.13e-21 · Best GWAS P=2.35e-18 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NOSTRIN 0.14 0.13 lasso 4 0.12 1.9e-14 -8.7 9.5 3.1e-21 -0.97 0.00 1.00 TRUE
2 GTEx Adipose Subcutaneous NOSTRIN 0.11 0.03 lasso 4 0.04 1.6e-04 -6.8 5.6 2.6e-08 -0.22 0.24 0.70 FALSE
3 GTEx Adrenal Gland NOSTRIN 0.21 0.09 lasso 4 0.09 4.1e-04 7.0 7.2 7.8e-13 -0.40 0.34 0.37 FALSE
4 GTEx Lung NOSTRIN 0.09 0.06 lasso 4 0.07 7.1e-06 8.3 7.6 2.8e-14 -0.39 0.07 0.91 FALSE
5 GTEx Pancreas NOSTRIN 0.30 0.12 enet 17 0.08 3.3e-04 -6.8 6.6 3.4e-11 -0.47 0.17 0.77 FALSE
6 GTEx Stomach NOSTRIN 0.15 0.04 enet 9 0.09 6.8e-05 8.3 8.8 1.7e-18 -0.58 0.09 0.89 FALSE
7 GTEx Testis NOSTRIN 0.43 0.17 enet 17 0.32 1.0e-14 -6.2 7.7 2.0e-14 -0.68 0.08 0.92 FALSE
8 METSIM Adipose NOSTRIN 0.07 0.09 lasso 6 0.08 1.6e-12 8.3 8.2 1.9e-16 -0.59 0.08 0.92 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma NOSTRIN 0.03 0.01 blup 55 0.02 9.5e-05 -6.5 7.2 5.0e-13 -0.37 0.02 0.94 FALSE
10 The Cancer Genome Atlas Colon Adenocarcinoma G6PC2 0.32 0.07 blup 29 0.06 3.8e-04 -6.1 -7.7 1.6e-14 0.79 0.02 0.77 FALSE
11 The Cancer Genome Atlas Glioblastoma Multiforme NOSTRIN 0.25 0.01 blup 55 0.08 2.0e-03 -6.5 5.9 3.5e-09 -0.25 0.01 0.62 FALSE
12 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NOSTRIN 0.09 0.03 enet 5 0.09 1.7e-10 6.3 5.7 1.2e-08 -0.19 0.04 0.96 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma G6PC2 0.47 0.23 enet 8 0.28 4.4e-32 -6.1 -7.0 2.9e-12 0.79 0.32 0.68 FALSE
14 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NOSTRIN 0.12 0.13 lasso 7 0.14 4.5e-15 -6.5 7.5 4.2e-14 -0.43 0.06 0.94 FALSE
15 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma G6PC2 0.56 0.13 blup 29 0.16 2.1e-09 -6.1 -7.3 2.1e-13 0.75 0.05 0.95 FALSE
16 The Cancer Genome Atlas Brain Lower Grade Glioma NOSTRIN 0.08 0.01 enet 6 0.04 2.1e-05 6.8 7.5 5.1e-14 -0.32 0.01 0.98 FALSE
17 The Cancer Genome Atlas Lung Adenocarcinoma NOSTRIN 0.04 0.00 blup 55 0.01 1.6e-02 7.0 5.3 9.2e-08 -0.23 0.00 0.98 FALSE
18 The Cancer Genome Atlas Lung Squamous Cell Carcinoma NOSTRIN 0.05 0.00 blup 55 0.01 1.1e-02 -6.5 7.0 2.0e-12 -0.38 0.01 0.70 FALSE
19 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma NOSTRIN 0.17 0.07 lasso 2 0.08 4.3e-04 6.3 6.9 3.9e-12 -0.44 0.01 0.95 FALSE
20 The Cancer Genome Atlas Prostate Adenocarcinoma NOSTRIN 0.06 0.01 blup 55 0.01 2.9e-02 -5.7 5.7 1.5e-08 -0.23 0.09 0.77 FALSE
21 The Cancer Genome Atlas Stomach Adenocarcinoma G6PC2 0.22 0.01 enet 4 0.08 3.1e-06 -6.1 -5.8 7.8e-09 0.71 0.08 0.52 FALSE
22 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma NOSTRIN 0.27 0.04 lasso 3 0.08 2.8e-03 7.0 6.6 4.9e-11 -0.44 0.01 0.59 FALSE