[Hub]/) : Traits : Whole body fat-free mass : ← →

chr2:168,949,234-170,419,444

Best TWAS P=3.13e-21 · Best GWAS P=2.35e-18 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	NOSTRIN	0.14	0.13	lasso	4	0.12	1.9e-14	-8.7	9.5	3.1e-21	-0.97	0.00	1.00	TRUE
6	GTEx	Stomach	NOSTRIN	0.15	0.04	enet	9	0.09	6.8e-05	8.3	8.8	1.7e-18	-0.58	0.09	0.89	FALSE
8	METSIM	Adipose	NOSTRIN	0.07	0.09	lasso	6	0.08	1.6e-12	8.3	8.2	1.9e-16	-0.59	0.08	0.92	FALSE
10	The Cancer Genome Atlas	Colon Adenocarcinoma	G6PC2	0.32	0.07	blup	29	0.06	3.8e-04	-6.1	-7.7	1.6e-14	0.79	0.02	0.77	FALSE
7	GTEx	Testis	NOSTRIN	0.43	0.17	enet	17	0.32	1.0e-14	-6.2	7.7	2.0e-14	-0.68	0.08	0.92	FALSE
4	GTEx	Lung	NOSTRIN	0.09	0.06	lasso	4	0.07	7.1e-06	8.3	7.6	2.8e-14	-0.39	0.07	0.91	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	NOSTRIN	0.12	0.13	lasso	7	0.14	4.5e-15	-6.5	7.5	4.2e-14	-0.43	0.06	0.94	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	NOSTRIN	0.08	0.01	enet	6	0.04	2.1e-05	6.8	7.5	5.1e-14	-0.32	0.01	0.98	FALSE
15	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	G6PC2	0.56	0.13	blup	29	0.16	2.1e-09	-6.1	-7.3	2.1e-13	0.75	0.05	0.95	FALSE
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	NOSTRIN	0.03	0.01	blup	55	0.02	9.5e-05	-6.5	7.2	5.0e-13	-0.37	0.02	0.94	FALSE
3	GTEx	Adrenal Gland	NOSTRIN	0.21	0.09	lasso	4	0.09	4.1e-04	7.0	7.2	7.8e-13	-0.40	0.34	0.37	FALSE
18	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	NOSTRIN	0.05	0.00	blup	55	0.01	1.1e-02	-6.5	7.0	2.0e-12	-0.38	0.01	0.70	FALSE
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	G6PC2	0.47	0.23	enet	8	0.28	4.4e-32	-6.1	-7.0	2.9e-12	0.79	0.32	0.68	FALSE
19	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	NOSTRIN	0.17	0.07	lasso	2	0.08	4.3e-04	6.3	6.9	3.9e-12	-0.44	0.01	0.95	FALSE
5	GTEx	Pancreas	NOSTRIN	0.30	0.12	enet	17	0.08	3.3e-04	-6.8	6.6	3.4e-11	-0.47	0.17	0.77	FALSE
22	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	NOSTRIN	0.27	0.04	lasso	3	0.08	2.8e-03	7.0	6.6	4.9e-11	-0.44	0.01	0.59	FALSE
11	The Cancer Genome Atlas	Glioblastoma Multiforme	NOSTRIN	0.25	0.01	blup	55	0.08	2.0e-03	-6.5	5.9	3.5e-09	-0.25	0.01	0.62	FALSE
21	The Cancer Genome Atlas	Stomach Adenocarcinoma	G6PC2	0.22	0.01	enet	4	0.08	3.1e-06	-6.1	-5.8	7.8e-09	0.71	0.08	0.52	FALSE
12	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NOSTRIN	0.09	0.03	enet	5	0.09	1.7e-10	6.3	5.7	1.2e-08	-0.19	0.04	0.96	FALSE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	NOSTRIN	0.06	0.01	blup	55	0.01	2.9e-02	-5.7	5.7	1.5e-08	-0.23	0.09	0.77	FALSE
2	GTEx	Adipose Subcutaneous	NOSTRIN	0.11	0.03	lasso	4	0.04	1.6e-04	-6.8	5.6	2.6e-08	-0.22	0.24	0.70	FALSE
17	The Cancer Genome Atlas	Lung Adenocarcinoma	NOSTRIN	0.04	0.00	blup	55	0.01	1.6e-02	7.0	5.3	9.2e-08	-0.23	0.00	0.98	FALSE