Hub : Genes

NOSTRIN

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1360	0.0330	5.2e-07	0.132	0.083	0.114	0.108	0.120	1.0e-15	2.9e-10	1.1e-13	4.3e-13	1.9e-14
2	GTEx	Adipose Subcutaneous	0.1080	0.0370	1.0e-03	0.025	NA	0.035	NA	0.044	3.4e-03	NA	7.0e-04	NA	1.6e-04
3	GTEx	Adrenal Gland	0.2124	0.0806	8.8e-03	0.091	NA	0.045	NA	0.090	3.7e-04	NA	1.0e-02	NA	4.1e-04
4	GTEx	Artery Aorta	0.3590	0.0800	5.3e-05	0.008	NA	-0.005	NA	0.002	1.1e-01	NA	9.4e-01	NA	2.3e-01
5	GTEx	Cells EBV-transformed lymphocytes	0.3980	0.0940	2.3e-04	0.402	NA	0.288	NA	0.357	2.8e-14	NA	5.4e-10	NA	1.7e-12
6	GTEx	Esophagus Mucosa	0.1370	0.0540	4.0e-03	-0.004	NA	0.001	NA	-0.004	9.0e-01	NA	2.5e-01	NA	7.9e-01
7	GTEx	Esophagus Muscularis	0.1770	0.0570	9.1e-04	-0.004	NA	0.064	NA	-0.004	8.5e-01	NA	9.9e-05	NA	6.4e-01
8	GTEx	Lung	0.0941	0.0355	1.9e-03	0.055	NA	0.040	NA	0.067	4.8e-05	NA	4.5e-04	NA	7.1e-06
9	GTEx	Nerve Tibial	0.1716	0.0515	1.1e-04	0.074	NA	0.050	NA	0.085	6.1e-06	NA	1.9e-04	NA	1.3e-06
10	GTEx	Pancreas	0.2960	0.0700	3.0e-06	0.123	NA	0.078	NA	0.028	7.7e-06	NA	3.3e-04	NA	2.4e-02
11	GTEx	Skin Sun Exposed Lower leg	0.1400	0.0400	4.4e-05	0.037	NA	0.023	NA	0.019	4.5e-04	NA	4.5e-03	NA	8.8e-03
12	GTEx	Stomach	0.1540	0.0580	5.8e-03	0.043	NA	0.085	NA	0.062	4.0e-03	NA	6.8e-05	NA	6.5e-04
13	GTEx	Testis	0.4260	0.0740	1.9e-09	0.166	NA	0.318	NA	0.294	7.9e-08	NA	1.1e-14	NA	1.5e-13
14	METSIM	Adipose	0.0747	0.0195	1.4e-08	0.091	0.069	0.075	0.070	0.084	1.5e-13	1.6e-10	2.3e-11	1.0e-10	1.6e-12
15	ROSMAP	Brain Pre-frontal Cortex	0.0795	0.0272	8.7e-04	0.006	0.022	0.021	0.022	0.015	5.2e-02	5.9e-04	9.0e-04	7.4e-04	4.2e-03
16	TCGA	Breast Invasive Carcinoma	0.0299	0.0140	4.5e-04	0.014	0.018	0.010	NA	0.016	4.7e-04	9.5e-05	2.9e-03	NA	2.2e-04
17	TCGA	Glioblastoma Multiforme	0.2480	0.0890	6.7e-04	0.005	0.080	0.037	NA	0.001	2.1e-01	2.0e-03	2.7e-02	NA	2.8e-01
18	TCGA	Head and Neck Squamous Cell Carcinoma	0.0928	0.0302	3.3e-08	0.034	0.076	0.092	NA	0.091	8.4e-05	6.5e-09	1.7e-10	NA	2.3e-10
19	TCGA	Kidney Renal Clear Cell Carcinoma	0.1217	0.0340	3.2e-13	0.129	0.105	0.133	NA	0.136	2.5e-14	7.8e-12	9.8e-15	NA	4.5e-15
20	TCGA	Brain Lower Grade Glioma	0.0775	0.0317	4.0e-05	0.008	0.029	0.040	NA	0.028	3.6e-02	2.8e-04	2.1e-05	NA	3.1e-04
21	TCGA	Lung Adenocarcinoma	0.0401	0.0203	3.0e-03	0.005	0.011	-0.001	NA	0.000	8.0e-02	1.6e-02	4.1e-01	NA	3.1e-01
22	TCGA	Lung Squamous Cell Carcinoma	0.0496	0.0249	4.3e-03	0.001	0.013	0.008	NA	0.004	2.1e-01	1.1e-02	3.4e-02	NA	1.1e-01
23	TCGA	Pheochromocytoma and Paraganglioma	0.1690	0.0630	2.6e-04	0.070	0.065	0.038	NA	0.080	9.7e-04	1.5e-03	1.3e-02	NA	4.3e-04
24	TCGA	Prostate Adenocarcinoma	0.0606	0.0248	4.1e-04	0.008	0.010	0.003	NA	0.006	4.7e-02	2.9e-02	1.5e-01	NA	7.6e-02
25	TCGA	Uterine Corpus Endometrial Carcinoma	0.2730	0.1090	5.5e-03	0.039	0.051	0.080	NA	0.081	2.9e-02	1.5e-02	3.0e-03	NA	2.8e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25
Forced expiratory volume in 1-second (FEV1), predicted	11.5	23.8	50.6	7.1	4.8	6.6	-1.0	0.3	3.3	5.2	1.0	6.5	4.0	6.4	7.1	6.1	3.6	5.9	4.3	3.9	5.9	5.5	3.7	4.4	5.6	3.5	5.4
Blood White Count	10.8	79.9	151.3	-12.3	-8.5	-10.4	1.6	0.7	-6.4	-11.5	-3.4	-10.0	-5.9	-11.8	-11.6	-11.6	-6.4	-10.3	-9.3	-9.0	-10.5	-8.1	-9.1	-9.3	-10.3	-9.0	-9.4
Trunk predicted mass	8.2	47.1	106.1	10.3	6.3	8.1	-0.5	-0.1	1.7	8.4	2.0	7.5	4.5	9.7	8.5	9.0	3.1	8.1	6.7	6.5	8.5	8.4	6.2	7.7	7.9	6.3	7.5
Trunk fat-free mass	8.1	46.5	104.0	10.2	6.3	8.1	-0.6	-0.1	1.7	8.4	2.0	7.4	4.5	9.7	8.5	8.9	3.0	8.1	6.7	6.5	8.5	8.4	6.1	7.7	7.8	6.2	7.4
Standing height	7.6	75.6	158.8	12.6	8.3	10.3	-1.6	-0.3	4.0	10.9	2.7	10.2	6.2	11.8	11.1	11.6	5.6	10.3	8.2	8.4	11.0	9.6	8.0	8.8	9.8	7.6	9.4
Height	7.5	145.2	246.5	15.1	12.2	13.7	-2.2	-2.4	5.5	14.9	5.4	14.2	9.7	15.7	14.6	15.1	8.2	14.3	12.6	12.8	14.8	12.7	12.0	12.9	14.0	12.1	12.7
Loud music exposure frequency	7.0	7.6	16.1	-0.4	-3.6	-2.6	3.4	4.0	-2.3	-2.9	-3.9	-2.1	-1.7	-2.1	-2.0	-2.6	-2.9	-2.6	-3.4	-3.2	-2.7	-2.8	-3.0	-2.7	-2.5	-3.0	-2.5
Fasting Glucose	6.7	8.0	43.0	5.5	-3.2	-2.0	1.4	5.0	2.5	0.3	-2.2	3.3	-1.5	-0.3	0.9	1.7	6.6	-0.7	-2.3	-2.6	-1.7	-2.3	-2.9	0.1	-3.1	-1.3	-4.1
Arm predicted mass (left)	6.7	34.1	83.2	9.1	5.1	6.6	-0.7	0.0	1.4	7.2	1.5	6.3	3.8	8.4	7.4	7.8	2.8	7.0	5.4	5.5	7.2	6.9	5.1	6.9	6.8	5.3	6.4
Whole body fat-free mass	6.6	37.6	89.5	9.5	5.6	7.2	-0.6	0.1	1.4	7.6	1.7	6.6	3.9	8.8	7.7	8.2	2.6	7.2	5.9	5.7	7.5	7.5	5.3	7.0	6.9	5.7	6.6
Whole body water mass	6.5	37.4	90.1	9.5	5.5	7.1	-0.6	0.1	1.4	7.6	1.6	6.6	4.0	8.8	7.6	8.2	2.6	7.2	5.8	5.6	7.5	7.4	5.3	7.0	7.0	5.6	6.6
Arm fat-free mass (left)	6.3	31.8	82.1	9.1	4.7	6.5	-0.8	0.4	1.1	6.9	1.2	6.1	3.4	8.2	7.2	7.6	2.7	6.8	5.1	5.1	6.9	6.7	5.0	6.6	6.5	5.0	6.2
Arm fat-free mass (right)	5.5	28.4	74.1	8.6	4.5	6.2	-0.6	0.6	1.2	6.5	1.0	5.8	3.1	7.6	6.8	7.0	2.3	6.5	5.0	4.9	6.6	6.5	4.7	6.3	6.1	4.9	5.6
Basal metabolic rate	5.4	29.8	74.6	8.6	4.8	6.4	-0.3	0.3	1.0	6.7	1.3	5.8	3.4	7.9	6.9	7.4	2.1	6.5	5.1	5.0	6.8	6.7	4.5	6.4	6.2	5.0	5.9
Sitting height	5.2	37.1	88.4	9.4	5.2	6.9	-1.1	0.5	3.6	7.5	1.2	7.5	4.9	8.5	8.1	8.2	4.8	7.5	5.4	5.4	7.4	6.5	5.6	6.2	6.6	4.9	6.0
Arm predicted mass (right)	5.0	25.5	69.4	8.3	4.2	5.9	-0.5	0.7	1.1	6.2	0.9	5.5	2.9	7.2	6.4	6.8	2.0	6.1	4.6	4.6	6.3	6.2	4.2	6.1	5.6	4.6	5.2
Peak expiratory flow (PEF)	4.7	10.9	24.8	4.3	3.7	5.0	-1.5	-0.4	1.0	3.3	1.0	4.3	1.5	4.6	4.1	3.7	1.8	4.1	3.0	3.2	4.7	3.7	2.3	2.9	4.1	2.2	4.0
Nervous feelings	4.6	8.7	15.2	-1.7	-3.1	-2.6	-0.5	2.5	-3.0	-3.9	-3.0	-3.5	-1.9	-3.4	-2.7	-3.4	-2.9	-3.5	-3.5	-3.6	-3.2	-2.8	-3.4	-2.9	-3.1	-3.4	-2.5
Leg fat-free mass (right)	4.6	24.5	62.3	7.9	4.5	5.7	-0.5	0.2	1.0	6.4	1.3	5.3	3.2	7.2	6.1	7.0	1.8	5.8	4.8	4.5	6.0	5.9	4.2	5.6	5.4	4.7	5.1
Ever had stillbirth, spontaneous miscarriage or termination	4.6	4.9	11.8	2.2	1.6	3.2	0.6	0.0	2.4	2.6	0.8	2.8	3.4	2.6	2.7	2.1	1.9	2.8	1.9	2.2	2.2	2.3	2.4	1.9	2.5	1.8	2.3
Leg predicted mass (right)	4.6	24.3	61.8	7.9	4.5	5.7	-0.4	0.2	1.0	6.3	1.2	5.3	3.2	7.2	6.1	7.0	1.8	5.8	4.7	4.4	6.0	5.9	4.2	5.6	5.4	4.6	5.1
Leg fat-free mass (left)	4.2	22.1	57.6	7.6	4.2	5.5	-0.4	0.4	0.7	5.9	1.1	4.9	3.0	6.9	5.9	6.5	1.7	5.5	4.4	4.2	5.8	5.8	3.9	5.4	5.2	4.3	5.0
Leg predicted mass (left)	4.2	22.0	58.2	7.6	4.2	5.5	-0.4	0.4	0.7	5.9	1.0	4.8	3.0	6.9	5.9	6.5	1.6	5.5	4.4	4.1	5.8	5.8	3.9	5.4	5.2	4.3	5.0
Forced expiratory volume in 1-second (FEV1), Best measure	4.0	12.6	30.6	3.7	3.9	5.5	-1.9	-0.5	1.8	3.9	1.1	3.9	2.4	4.6	4.1	3.6	1.5	5.4	3.1	3.9	5.2	3.8	3.0	3.6	4.1	2.8	3.9
Guilty feelings	3.8	5.7	9.5	-1.5	-3.0	-2.5	0.7	2.3	-1.8	-2.9	-2.6	-3.1	-1.1	-2.8	-2.5	-2.6	-2.4	-2.5	-2.4	-3.0	-3.0	-2.8	-2.3	-2.2	-2.6	-1.9	-2.6
Commuting to job workplace: Public transport	3.8	4.5	10.9	1.7	1.3	2.2	0.5	-1.3	-0.0	2.3	2.1	2.5	1.8	1.9	2.3	2.0	3.3	2.9	2.6	2.6	2.1	1.2	3.1	2.2	2.5	2.6	1.8
Forced expiratory volume in 1-second (FEV1)	3.4	11.3	30.1	4.3	3.8	5.5	-1.9	0.1	1.0	3.7	0.8	3.8	1.8	4.3	4.2	3.7	1.4	4.7	2.8	3.5	5.1	3.5	2.3	3.3	3.8	2.5	3.7
Suffer from ‘nerves’	3.2	4.9	9.1	-1.2	-2.1	-2.2	0.9	2.0	-2.0	-2.9	-2.6	-2.0	-1.0	-2.4	-1.8	-2.2	-3.0	-2.6	-2.8	-2.9	-2.6	-2.1	-2.7	-2.4	-2.1	-2.4	-1.8
Severe depression (siblings)	3.1	3.5	7.7	-1.3	-2.0	-2.8	-2.4	0.9	-2.2	-1.9	-1.5	-1.6	-1.3	-1.8	-2.4	-1.6	-0.6	-2.4	-2.2	-2.1	-2.3	-2.1	-1.8	-1.9	-1.8	-1.8	-1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.1	3.7	8.1	2.1	2.8	1.2	0.0	-1.5	1.9	1.9	1.6	2.1	0.2	2.5	2.5	2.8	-0.3	1.2	2.3	1.5	2.1	2.4	1.0	2.3	2.2	2.4	2.1
Hand grip strength (right)	3.0	8.0	20.2	3.5	2.8	4.5	-2.3	-0.4	0.9	3.6	0.8	2.9	1.5	3.6	3.4	3.4	2.2	3.2	2.3	2.8	3.6	3.5	2.8	1.9	3.3	1.7	3.9
Body Mass Index (BMI) (2010)	2.9	3.9	8.3	-2.3	-1.9	-2.5	0.6	-0.3	-1.1	-2.1	-0.4	-2.7	-1.9	-2.5	-2.9	-2.4	-1.2	-2.0	-1.7	-1.9	-2.5	-1.6	-1.2	-2.0	-2.8	-1.9	-2.6
Neuroticism (2016)	2.9	4.2	9.1	-1.1	-2.8	-2.3	0.1	1.9	-0.5	-2.6	-2.2	-2.0	-0.9	-2.1	-1.6	-1.9	-1.0	-2.1	-2.2	-2.8	-2.9	-3.0	-2.2	-2.2	-2.3	-2.2	-2.1
Age when periods started (menarche)	2.9	7.0	13.5	2.9	3.1	3.7	1.1	-1.0	1.4	3.4	1.5	3.2	3.4	3.1	3.4	3.7	1.2	3.1	2.5	2.6	3.2	1.8	1.9	1.9	3.1	2.4	2.9
Forced vital capacity (FVC), Best measure	2.9	10.7	26.3	4.0	3.4	5.0	-2.3	-0.2	1.4	3.8	0.7	3.4	2.2	4.4	3.8	3.6	1.6	5.1	2.6	3.6	4.7	3.1	3.0	3.1	3.7	2.3	3.4
Lupus	2.8	4.3	9.9	-3.1	-0.8	-2.0	0.2	0.1	-1.2	-2.0	-0.3	-2.4	-1.1	-2.6	-3.1	-2.5	-2.5	-2.9	-1.2	-1.6	-2.2	-2.0	-2.2	-2.9	-2.4	-1.7	-2.6
Taking other prescription medications	2.7	4.1	7.7	-2.6	-2.5	-2.4	0.2	0.7	-2.4	-2.2	-0.8	-2.1	-2.0	-2.8	-2.4	-2.6	-0.2	-1.9	-2.2	-1.6	-2.4	-2.4	-1.9	-1.6	-2.2	-1.7	-2.5
Past tobacco smoking	2.6	4.8	14.1	-3.8	-1.1	-1.9	-0.0	0.0	0.6	-3.3	-0.5	-1.9	-2.6	-3.1	-2.8	-3.5	-1.2	-2.6	-2.1	-1.8	-1.9	-2.1	-2.8	-2.5	-2.0	-2.1	-2.0
Worrier / anxious feelings	2.6	4.8	12.0	-2.7	-1.5	-2.5	0.6	0.2	-1.5	-2.9	-0.7	-2.5	-0.8	-3.5	-2.3	-2.6	-0.9	-3.2	-1.7	-2.7	-2.7	-2.8	-2.2	-2.5	-2.9	-1.5	-2.1
Forced vital capacity (FVC)	2.5	9.6	23.7	4.4	3.2	4.9	-2.3	0.5	0.8	3.6	0.3	3.2	1.6	4.1	3.9	3.4	1.5	4.5	2.5	3.2	4.6	3.0	2.5	3.0	3.5	2.1	3.3
Neuroticism score	2.5	5.2	9.9	-0.3	-2.4	-2.3	0.2	2.1	-2.0	-2.9	-2.3	-2.1	-1.8	-2.6	-1.3	-2.0	-1.2	-2.6	-2.6	-3.1	-2.5	-2.9	-3.1	-2.2	-3.0	-2.3	-2.6
Depression (self-reported)	2.5	3.0	8.8	-3.0	-1.3	-2.4	-0.6	-0.7	-0.5	-2.1	-0.0	-2.5	-2.2	-2.4	-2.4	-2.5	-1.3	-1.5	-1.1	-0.8	-1.4	-2.1	-1.2	-0.8	-2.0	-0.9	-2.2
Financial situation satisfaction	2.5	3.1	7.7	-1.0	-1.8	-1.2	1.7	1.8	-0.1	-2.7	-2.0	-1.8	-0.7	-2.2	-0.9	-1.9	-2.7	-2.1	-1.7	-2.5	-1.7	-1.2	-2.8	-1.5	-1.8	-1.5	-1.1
Heart disease (siblings)	2.5	3.1	8.5	-1.2	-0.9	-1.8	2.7	0.6	-2.5	-2.1	-0.5	-2.2	-1.2	-2.3	-1.6	-1.8	-1.4	-2.9	-1.0	-1.9	-2.0	-2.0	-1.9	-1.6	-2.1	-0.9	-1.1
Worry (Nagel 2018)	2.4	5.0	10.0	-1.6	-2.1	-2.2	-0.1	1.4	-2.1	-3.2	-2.0	-2.5	-0.5	-2.7	-1.7	-2.4	-2.2	-2.9	-2.5	-3.0	-2.7	-2.4	-2.7	-2.7	-2.6	-2.3	-1.9
Noisy workplace	2.4	3.0	7.0	-1.0	-2.0	-1.0	1.0	1.8	-1.4	-2.5	-1.8	-1.9	-1.9	-2.2	-0.6	-2.2	-1.2	-2.0	-1.8	-2.4	-1.8	-0.9	-2.6	-1.5	-1.8	-1.7	-1.0
HbA1C	2.3	2.6	8.0	2.8	-0.9	-1.1	-0.2	2.5	2.8	-0.5	-1.6	1.2	-1.0	-0.5	1.0	0.8	2.3	-1.1	-1.0	-2.1	-1.2	-1.4	-2.2	-0.7	-2.1	-1.0	-2.7
Financial difficulties in last 2 years	2.3	3.0	7.7	-0.5	-2.1	-2.0	1.0	1.4	0.5	-2.2	-1.7	-1.3	-0.4	-1.9	-1.2	-1.3	-1.3	-2.2	-2.3	-2.8	-2.2	-1.3	-2.5	-1.9	-2.3	-2.0	-1.7
Neuroticism (Nagel 2018)	2.2	5.3	11.1	-1.0	-2.2	-2.5	0.1	1.7	-2.0	-3.3	-2.1	-2.2	-1.0	-2.4	-1.4	-2.3	-2.1	-2.7	-2.7	-2.9	-2.4	-3.1	-3.3	-2.4	-2.7	-2.2	-2.5
Rheumatoid Arthritis	2.2	3.0	7.1	2.0	1.3	2.1	-1.0	0.2	-1.3	1.4	0.5	2.0	2.7	1.6	2.4	1.5	0.9	2.5	2.0	1.6	2.4	1.2	1.1	2.4	1.9	2.1	1.6
Medication: Ramipril	2.2	2.9	6.1	0.2	2.0	1.3	-1.9	-2.4	1.2	1.8	2.5	1.9	1.0	1.7	1.5	1.6	1.0	1.7	1.7	2.4	1.7	1.3	1.8	1.8	1.8	1.9	2.0
Weight	2.2	10.9	30.9	5.6	2.8	3.7	0.6	0.3	-0.3	4.0	0.7	3.2	1.5	4.9	4.3	4.6	0.6	4.0	2.9	2.9	4.2	4.1	2.2	4.2	3.8	3.1	3.6
Happiness	2.2	2.7	6.0	-1.3	-2.2	-0.6	-0.9	2.4	-1.3	-2.3	-2.4	-1.4	0.1	-1.8	-0.9	-1.9	-1.9	-1.5	-2.1	-2.4	-2.0	-1.1	-1.8	-1.5	-1.1	-1.7	-0.7
Medication: Amlodipine	2.2	3.0	8.0	-0.9	-1.9	-1.4	0.4	1.4	-0.3	-1.5	-1.7	-1.2	-0.6	-1.9	-1.4	-1.3	-1.2	-2.2	-2.6	-2.2	-2.3	-2.4	-2.8	-2.3	-2.0	-2.1	-1.9
Medication: Blood pressure	2.1	3.8	7.3	-2.0	-1.9	-2.3	2.7	0.6	-1.1	-2.5	-0.7	-2.4	-1.9	-2.4	-1.9	-2.1	-1.6	-2.3	-1.8	-2.2	-2.4	-2.4	-2.4	-1.1	-2.0	-1.2	-1.8
Overall health rating	2.1	4.5	9.4	-1.7	-2.7	-2.8	1.9	1.6	-1.6	-3.1	-2.0	-1.9	-1.2	-2.5	-1.7	-2.9	-0.8	-2.4	-2.4	-2.4	-2.6	-1.6	-2.3	-1.5	-2.5	-1.9	-2.5
Bipolar Disorder (2018)	2.0	3.1	8.7	-0.7	-3.0	-2.2	0.3	2.5	-1.6	-1.9	-2.6	-1.9	-0.1	-1.5	-1.7	-1.8	-1.2	-1.7	-2.1	-2.0	-2.4	-1.8	-1.2	-1.2	-1.4	-1.7	-1.5
Coronary Artery Disease (CAD)	2.0	2.4	5.6	1.1	1.9	0.5	0.2	-1.3	1.6	1.8	1.8	2.1	1.7	1.6	1.0	1.8	2.4	1.5	1.9	1.7	1.4	1.9	1.3	2.2	1.0	1.8	0.4
Cardiovascular Disease	2.0	6.5	15.3	-3.0	-2.4	-2.9	0.7	0.4	-1.7	-3.4	-1.0	-2.5	-1.5	-2.9	-2.4	-3.2	-0.5	-3.0	-3.6	-2.7	-2.9	-2.7	-3.9	-2.7	-2.5	-3.2	-2.2
Hand grip strength (left)	2.0	5.2	15.3	3.5	1.7	3.9	-2.1	0.8	0.9	2.2	-0.6	2.4	0.9	3.0	3.1	2.4	1.5	2.6	1.1	1.6	3.0	3.1	1.9	1.1	2.8	0.4	3.5
Health satisfaction	2.0	2.5	8.9	-1.2	-2.1	-1.3	0.0	1.5	-1.2	-1.8	-2.0	-2.3	-1.3	-1.6	-1.9	-2.0	-3.0	-1.2	-2.2	-1.3	-1.2	-0.6	-1.6	-0.8	-1.1	-1.8	-1.0
Heart disease (mother)	2.0	2.5	5.4	-0.1	-2.0	-1.6	-0.0	1.4	-1.0	-2.0	-1.6	-2.3	-0.9	-1.8	-1.1	-1.9	-0.7	-1.7	-1.9	-2.0	-2.0	-1.4	-1.2	-1.4	-2.1	-1.8	-1.9
Qualifications: nursing, teaching	2.0	3.2	8.1	-0.3	-1.9	-1.1	-0.1	2.3	-2.0	-2.0	-2.4	-2.1	-1.1	-2.0	-1.5	-1.7	-2.8	-1.7	-1.7	-2.3	-1.9	-1.8	-0.9	-2.3	-1.9	-1.7	-1.2
Ever taken oral contraceptive pill	2.0	2.2	5.0	1.8	1.4	1.9	0.5	0.4	0.9	1.2	0.4	2.2	0.1	1.5	2.1	1.6	0.8	1.6	1.9	1.2	1.7	1.8	1.2	1.9	1.8	1.8	2.0
Ever smoked	2.0	3.5	10.6	3.3	0.9	2.0	0.2	0.3	-0.7	2.9	0.3	1.6	2.5	2.5	2.5	2.8	1.3	2.2	1.8	1.7	1.7	1.8	2.3	1.7	1.6	1.5	1.6
Bipolar Disorder or Schizophrenia	1.9	4.7	11.6	-1.0	-3.4	-2.9	0.5	2.5	-0.7	-2.1	-2.8	-1.9	0.1	-2.1	-2.3	-2.2	-1.2	-2.5	-2.9	-2.4	-3.0	-2.9	-1.4	-2.3	-2.3	-2.1	-1.8
Schizophrenia (2014)	1.9	4.2	8.1	-2.0	-2.6	-2.6	1.1	1.3	-1.2	-2.4	-1.7	-1.7	-0.3	-2.4	-2.4	-2.6	-1.7	-2.6	-2.9	-1.9	-2.5	-2.7	-1.6	-2.4	-2.1	-2.1	-1.2
Lung FEV1/FVC ratio	1.9	9.8	21.5	2.8	4.6	3.8	0.5	-2.6	2.0	3.6	3.4	3.2	1.8	3.9	3.1	4.0	1.1	3.0	4.0	3.3	4.0	3.4	2.5	3.3	3.0	3.6	2.9
Eye problems/disorders: Diabetes related eye disease	1.9	2.1	6.1	0.5	2.5	1.4	-1.8	-2.3	-0.9	1.5	2.2	1.2	1.2	1.7	1.0	1.5	0.2	1.6	1.1	1.8	2.1	0.6	0.6	1.3	1.3	1.1	1.5
Exposure to tobacco smoke outside home	1.9	2.6	6.0	-0.8	-2.3	-1.3	0.3	2.2	0.4	-2.3	-2.5	-1.7	-1.2	-1.6	-1.0	-1.7	-0.7	-1.7	-1.8	-2.3	-1.7	-1.3	-1.9	-1.8	-1.2	-1.8	-1.0
Comparative body size at age 10	1.9	5.1	12.2	-2.7	-1.8	-3.0	1.1	0.2	-2.8	-2.5	-0.7	-3.4	-2.0	-2.5	-3.5	-2.9	-3.0	-2.3	-1.8	-1.6	-2.0	-2.1	-2.1	-1.5	-2.4	-1.6	-2.5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.4	7.0	-2.3	-1.7	-1.1	1.1	0.1	-0.9	-1.9	-0.6	-2.6	-0.3	-2.2	-1.8	-2.1	-1.7	-1.6	-1.6	-1.6	-2.2	-1.0	-1.0	-1.4	-1.8	-1.3	-1.4
Medication: Aspirin	1.9	2.5	5.8	1.4	1.7	1.2	-0.1	-1.1	0.9	1.7	1.8	1.5	0.5	1.4	1.8	1.3	1.5	1.5	2.1	2.1	1.9	1.5	1.8	2.2	1.4	2.4	1.5
High cholesterol (Self-reported)	1.9	3.4	10.0	-3.2	-1.2	-3.0	1.1	-1.7	-0.6	-1.5	1.0	-1.6	0.2	-2.5	-2.5	-1.8	-0.2	-2.2	-1.4	-1.1	-2.3	-2.0	-1.7	-1.5	-2.4	-1.1	-2.8
Alcohol drinker status: Never	1.9	2.3	8.0	-2.8	-0.6	-2.2	0.4	-1.4	0.5	-1.6	1.0	-1.6	-1.6	-2.2	-2.4	-2.0	-0.7	-2.1	-0.6	-0.5	-1.3	-1.9	-1.2	-1.0	-1.9	-0.5	-1.4
Neuroticism	1.8	4.4	8.5	0.0	-2.4	-1.8	-0.5	2.3	-1.6	-2.5	-2.6	-2.2	-0.9	-2.0	-0.8	-1.6	-1.7	-2.3	-2.5	-2.9	-2.3	-2.5	-2.9	-2.5	-2.5	-2.6	-2.2
Number of treatments/medications taken	1.8	3.2	8.0	-2.5	-2.0	-2.0	-0.3	0.2	-1.1	-2.5	-0.3	-1.7	-1.4	-2.7	-2.0	-2.7	0.1	-1.3	-1.8	-1.7	-2.4	-2.8	-1.8	-1.2	-2.0	-1.2	-2.3
Sensitivity / hurt feelings	1.8	3.0	7.8	-1.4	-1.0	-2.1	-0.1	0.4	-2.1	-2.2	-0.7	-1.5	-2.0	-2.3	-2.0	-1.9	-0.7	-2.1	-1.2	-1.6	-1.4	-2.3	-2.4	-1.5	-2.4	-1.5	-2.8
Diverticular disease/diverticulitis (self-reported)	1.8	2.2	5.6	-0.8	1.7	0.7	1.2	-2.2	1.9	1.5	2.2	1.0	1.3	0.8	0.2	0.6	-0.3	1.6	1.3	2.4	1.8	1.3	1.4	2.2	1.4	2.0	1.5
Commuting to job workplace: Cycle	1.8	2.2	6.7	2.4	1.2	1.9	-1.0	0.1	0.7	2.5	0.2	1.6	2.3	1.8	1.7	2.6	1.4	1.6	1.1	1.2	0.9	0.7	1.7	0.5	1.4	0.8	0.8
Breast Cancer	1.7	4.1	11.1	2.7	2.5	3.3	-0.7	-0.8	0.1	1.9	1.5	1.9	1.3	2.1	3.1	2.4	0.1	2.3	1.9	1.6	2.5	2.5	1.6	2.2	2.2	1.9	2.3
Ulcerative Colitis	1.7	2.4	4.9	1.1	1.9	1.9	-1.5	-0.4	0.4	0.9	0.8	1.8	2.2	1.3	1.5	0.9	0.2	2.1	2.1	1.6	2.2	1.4	1.4	2.2	1.6	2.1	1.7
Number of full sisters	1.7	2.0	8.6	-1.9	-0.2	-2.9	1.4	-1.9	-0.9	-0.7	1.1	-1.5	-0.8	-1.4	-2.1	-0.7	-0.0	-2.0	-0.4	-0.7	-1.3	-1.3	-1.1	-1.2	-2.3	-0.7	-1.9
Smoking status: Previous	1.7	2.6	8.8	2.8	0.6	1.2	0.5	-0.1	-0.2	3.0	0.5	1.1	2.0	2.2	1.7	2.9	1.0	1.8	1.5	1.3	1.1	1.4	2.3	1.7	1.1	1.5	1.1
Breast cancer (self-reported)	1.7	2.0	4.6	1.6	1.8	0.8	1.9	-0.4	1.7	2.0	0.7	1.9	1.1	1.7	1.4	2.1	0.5	0.4	1.6	1.2	1.5	2.2	1.3	0.8	1.1	1.1	1.8
Illnesses of father: None of the above (group 1)	1.7	2.1	5.0	-0.5	-1.0	-1.0	1.0	1.5	-0.5	-1.3	-1.2	-1.2	-2.2	-1.9	-1.4	-1.2	-1.3	-1.7	-1.6	-1.5	-1.6	-1.8	-2.2	-1.9	-1.5	-1.4	-1.4
Tinnitus: Yes, now most or all of the time	1.7	2.0	7.3	-1.6	-1.7	-2.0	-0.9	0.5	0.6	-1.6	-0.5	-1.6	-2.7	-1.7	-1.9	-2.0	0.6	-2.1	-1.0	-1.0	-1.8	-1.1	-0.4	-1.1	-1.5	-0.8	-0.8
Number of children fathered	1.6	1.8	3.9	0.4	1.5	0.9	-0.9	-1.3	-1.9	0.9	1.9	0.7	0.9	0.9	0.8	0.3	1.3	1.3	1.7	2.0	1.5	0.9	1.6	1.8	1.5	1.9	1.9
Pulse wave peak to peak time	1.6	1.9	5.7	2.4	1.0	1.7	-0.9	0.3	2.2	2.0	-0.1	1.8	0.1	1.7	1.7	2.1	1.5	2.0	0.8	0.9	1.3	0.9	1.3	1.1	0.9	0.6	0.2
Eye problems/disorders: None of the above	1.6	1.8	4.1	-1.7	-1.7	-1.2	0.8	0.9	0.0	-1.5	-1.0	-1.4	-0.9	-1.8	-1.5	-1.6	-0.5	-1.5	-1.4	-1.6	-2.0	-1.1	-1.8	-1.4	-1.1	-1.4	-1.5
Leg pain on walking	1.6	2.0	4.5	-1.0	-1.7	-1.6	0.8	0.6	-1.1	-1.7	-1.3	-2.1	-1.1	-1.6	-1.5	-1.7	-1.8	-0.9	-1.3	-1.3	-1.4	-2.1	-0.9	-1.1	-1.7	-1.3	-1.6
Commuting to job workplace: Car/motor vehicle	1.6	1.8	4.4	-1.2	-0.7	-2.0	0.9	0.1	-1.2	-1.7	-0.7	-1.4	-0.7	-1.3	-1.8	-1.3	-1.8	-2.1	-1.4	-1.5	-1.0	-0.2	-2.1	-1.0	-1.6	-1.2	-1.2
Commuting to job workplace: Walk	1.6	1.7	7.4	1.3	0.6	2.7	-0.6	0.1	-1.6	1.1	0.1	0.9	1.9	1.1	2.1	1.0	1.1	1.7	1.3	0.6	0.8	1.9	1.9	0.4	1.5	0.4	1.6
Blood Eosinophil Count	1.5	11.9	31.6	-5.6	-3.1	-4.5	-0.0	-0.9	-1.0	-4.6	-0.3	-4.3	-2.6	-5.1	-4.3	-5.0	-1.9	-3.6	-2.9	-3.1	-4.4	-3.3	-2.2	-2.8	-4.1	-2.4	-4.2
Illnesses of siblings	1.5	2.2	7.6	1.8	0.3	2.4	-2.8	0.9	1.4	1.6	-0.8	1.6	1.7	1.8	1.3	1.4	0.4	1.9	0.1	1.3	1.7	1.7	1.1	0.0	1.9	0.0	1.6
Handedness (chirality/laterality): Left-handed	1.5	1.8	4.2	-0.9	-1.5	-1.0	-1.6	0.9	-0.7	-1.0	-1.1	-1.6	-0.9	-1.2	-1.6	-1.4	0.8	-1.6	-1.2	-1.5	-2.0	-1.3	-0.5	-1.9	-1.7	-1.6	-1.8
Supplements: Fish oil (including cod liver oil)	1.5	1.9	4.5	2.1	0.8	1.8	1.3	0.6	1.7	1.0	-0.3	1.6	1.6	1.5	1.4	1.2	0.8	1.7	1.4	1.2	1.8	1.2	1.3	1.5	1.9	1.2	1.8
Risk taking	1.5	2.2	5.4	1.6	1.4	2.0	-0.2	-0.1	-0.3	1.5	0.2	1.6	2.1	2.0	2.3	1.8	0.5	1.6	1.6	1.1	1.5	1.3	1.7	1.4	1.6	1.7	2.0
Unable to work because of sickness or disability	1.5	1.9	5.8	-1.1	-1.5	-2.4	0.7	0.1	-1.4	-1.4	-0.3	-1.6	-1.0	-1.7	-1.5	-1.3	-0.5	-1.6	-1.4	-1.2	-1.8	-1.5	-1.7	-1.1	-1.8	-0.9	-2.1
Medication: Simvastatin	1.4	2.0	7.0	-1.5	-1.0	-2.4	1.6	-0.6	0.7	-1.1	0.5	-1.6	-1.4	-1.8	-1.8	-1.4	0.3	-1.6	-1.0	-0.6	-1.6	-2.0	-1.6	-0.3	-1.9	-0.4	-2.6
Pulse rate	1.4	2.4	6.7	-1.1	-1.7	-2.6	0.9	0.9	-0.8	-1.8	-1.1	-1.6	-1.3	-1.1	-1.6	-1.2	-1.7	-2.0	-2.1	-1.7	-1.8	-1.2	-2.2	-1.1	-1.3	-1.8	-1.3
Mouth/teeth dental problems: Dentures	1.4	2.3	7.4	2.0	1.3	1.3	-0.4	-0.9	0.3	1.4	1.5	1.9	0.8	0.9	2.1	1.4	1.0	2.2	2.0	1.5	1.7	1.7	1.3	2.7	1.3	2.2	0.9
Number of self-reported non-cancer illnesses	1.4	2.4	7.0	-2.0	-1.9	-2.6	-0.6	0.2	-1.5	-1.9	-0.6	-1.7	-1.6	-1.9	-2.4	-2.0	0.1	-1.8	-1.7	-1.1	-1.7	-1.8	-1.7	-0.8	-1.3	-1.1	-1.2
Mean Putamen Volume	1.3	1.5	6.5	-1.1	-1.4	-0.3	1.6	0.9	-1.7	-1.0	-1.3	-2.1	0.1	-1.4	-1.1	-1.4	-2.5	-0.1	-1.1	-1.0	-0.9	-0.4	-0.8	-0.9	-1.3	-1.4	-1.5
Heel bone mineral density (BMD) T-score, automated (right)	1.3	2.9	5.5	-0.8	-2.1	-1.7	-0.0	1.7	-0.5	-1.7	-1.7	-2.0	-2.0	-1.8	-2.3	-1.9	-1.9	-1.4	-1.9	-1.9	-2.0	-1.4	-1.8	-1.3	-2.0	-1.6	-2.2
Blood clot in the leg (DVT)	1.3	1.7	6.7	-0.9	1.4	-0.1	0.2	-1.9	-0.6	1.0	2.4	0.6	0.6	0.8	0.1	0.5	0.4	0.3	2.0	1.9	1.3	1.5	1.0	2.0	1.1	2.6	1.4
Wheeze or whistling in the chest in last year	1.3	2.2	9.7	-1.2	-2.0	-3.1	1.3	0.3	-0.7	-1.6	-0.8	-0.9	-2.1	-1.2	-1.6	-1.4	0.7	-1.9	-1.3	-1.1	-1.9	-2.3	-0.8	-1.0	-1.4	-1.0	-1.7
Mean time to correctly identify matches	1.3	2.4	7.3	-2.7	-1.2	-1.9	0.3	-1.7	-1.6	-1.4	1.0	-2.3	-1.0	-2.3	-2.1	-1.9	-1.8	-1.2	-0.8	-0.5	-1.7	-2.3	-0.2	-0.8	-1.7	-0.1	-1.4
Pulse rate, automated reading	1.3	4.3	8.3	-2.2	-2.3	-2.9	0.3	0.3	-1.2	-2.2	-0.9	-2.6	-2.1	-2.3	-2.3	-2.2	-1.7	-2.8	-2.5	-2.1	-2.9	-1.9	-1.8	-2.0	-2.3	-2.2	-2.1
Fractured/broken bones in last 5 years	1.3	1.7	5.0	0.1	-0.8	-1.0	0.2	1.5	0.2	-1.7	-1.5	-0.9	-0.9	-1.4	-0.6	-0.9	-2.1	-1.5	-1.5	-2.2	-1.6	-1.1	-2.0	-1.5	-1.7	-1.1	-1.3
Deep venous thrombosis (DVT) (self-reported)	1.3	1.7	5.9	-0.6	1.5	-0.1	-0.1	-1.8	-0.7	1.2	2.2	1.0	0.8	1.0	0.2	0.7	0.6	0.5	1.8	2.0	1.5	1.4	0.9	2.0	1.2	2.4	1.4
Major Depression (MDD)	1.2	1.5	3.9	-1.9	-1.0	-1.4	-0.0	-0.3	-1.3	-0.8	-0.0	-2.0	-1.6	-1.5	-1.5	-1.1	-0.6	-1.7	-1.2	-0.7	-1.0	-1.6	-1.2	-1.4	-1.7	-1.0	-1.0
Reaction Time	1.2	2.3	8.5	-2.9	-1.0	-1.4	0.1	-1.7	-0.8	-1.5	1.1	-2.0	-1.0	-2.5	-2.2	-2.1	-0.9	-1.3	-1.0	-0.5	-1.5	-2.2	-0.5	-1.1	-1.8	-0.3	-1.4
Age at First Birth	1.2	1.7	6.5	1.2	0.9	1.1	-0.0	-0.8	1.2	1.6	1.0	1.7	0.8	1.6	0.8	1.0	2.2	1.8	1.5	1.5	1.0	1.4	2.5	0.8	1.4	1.1	0.7
Type 2 Diabetes (T2D) (2012)	1.2	1.3	5.0	-0.3	2.2	1.2	0.9	-2.2	-0.6	1.4	2.0	0.9	-0.4	1.0	0.6	1.0	-0.4	1.4	1.5	1.3	1.3	0.9	0.4	0.9	0.3	1.4	0.4
Diabetes (father)	1.2	1.5	9.1	-2.2	1.4	-1.0	1.4	-3.0	-0.2	0.2	2.7	-0.3	0.8	-0.5	-1.0	-0.6	-0.1	-0.3	1.3	1.6	0.5	-0.2	0.5	0.7	0.1	1.5	0.0
Maternal smoking around birth	1.2	1.7	8.0	2.8	0.5	0.8	0.5	1.3	-2.8	0.9	-0.9	0.7	0.0	1.8	2.0	2.1	-0.5	1.0	0.9	-0.3	0.9	0.7	0.6	1.2	1.1	1.1	1.7
Length of working week for main job	1.2	1.3	5.3	-1.0	-0.8	-1.4	1.0	0.3	-0.0	-1.2	-0.6	-1.2	-1.3	-0.8	-1.2	-1.0	-0.1	-1.3	-0.9	-1.4	-1.5	-2.3	-0.9	-1.2	-1.4	-0.8	-1.5
Gout (self-reported)	1.2	1.7	5.7	-1.3	-1.8	-1.0	-0.9	0.9	-2.4	-1.5	-1.1	-1.1	-0.9	-1.1	-1.4	-1.6	0.1	-0.9	-1.6	-1.2	-1.6	-1.1	-1.0	-1.7	-0.8	-1.6	-1.1
Chronic bronchitis/emphysema (mother)	1.2	1.4	7.2	2.7	0.6	0.8	-0.0	0.5	-0.8	1.8	0.2	1.3	1.4	1.5	0.9	2.1	1.4	1.2	0.9	0.8	1.2	0.4	0.9	1.1	0.7	0.9	0.9
High blood pressure (siblings)	1.2	1.8	5.5	-0.8	-1.3	-2.3	2.0	0.2	-0.8	-1.8	-0.4	-1.4	-2.3	-1.4	-1.0	-1.1	-1.0	-1.7	-0.7	-1.6	-1.8	-1.3	-1.2	-0.2	-1.4	-0.6	-1.4
Emphysema/chronic bronchitis	1.2	1.3	3.7	1.8	0.8	0.7	-0.6	-0.0	-0.1	1.3	0.1	0.7	-0.3	1.9	1.8	1.9	0.3	0.8	1.6	0.5	1.0	1.2	1.4	1.4	1.4	1.4	1.6
Loneliness, isolation	1.2	1.7	4.8	-1.2	-1.5	-1.9	1.0	0.3	-0.4	-2.2	-0.7	-1.4	-0.9	-2.0	-1.0	-1.9	-0.9	-0.9	-1.2	-1.1	-1.0	-1.8	-1.7	-0.1	-1.6	-0.5	-1.6
Eye problems/disorders: Glaucoma	1.2	1.4	3.0	1.2	1.2	1.2	0.9	-0.6	0.5	1.2	0.8	1.0	1.3	1.1	1.4	1.3	-0.7	1.4	1.3	1.3	1.4	0.9	1.1	1.7	1.3	1.7	1.3
Medication: Bendroflumethiazide	1.2	1.9	12.2	-3.5	-0.2	-1.6	-0.3	-2.0	-1.9	-1.6	1.5	-1.0	0.5	-1.7	-1.9	-2.0	0.2	-1.0	-0.7	-0.1	-0.9	-0.7	-1.4	-0.3	-1.1	-0.3	-1.1
Cholesterol lowering medication	1.2	1.8	4.4	-2.1	-0.9	-1.7	0.4	-0.6	-0.2	-1.8	0.3	-1.2	-0.2	-2.0	-1.5	-2.1	-0.4	-1.9	-1.1	-1.0	-1.8	-0.7	-1.3	-1.1	-1.6	-1.2	-1.6
Depression (Nagel 2018)	1.1	1.7	4.5	-1.3	-1.2	-1.5	0.8	0.1	-0.7	-2.1	-0.8	-1.6	-1.1	-1.6	-1.0	-1.5	-1.2	-2.0	-1.5	-1.4	-1.5	-1.0	-1.9	-1.2	-1.1	-1.2	-1.0
Angina	1.1	1.5	4.4	-0.3	-1.7	-1.9	1.4	0.7	1.0	-0.8	-0.5	-1.1	-0.7	-1.6	-0.9	-1.0	0.5	-1.4	-1.2	-1.0	-1.5	-1.2	-1.1	-1.2	-2.1	-1.0	-2.0
Fed-up feelings	1.1	1.9	8.2	-0.7	-1.3	-1.8	1.1	0.2	-0.5	-1.9	-0.6	-0.9	-1.8	-1.7	-0.8	-1.3	0.1	-1.3	-1.3	-1.7	-1.7	-2.9	-1.7	-1.0	-1.7	-0.8	-1.8
Mouth/teeth dental problems	1.1	1.7	4.7	-1.5	-1.5	-0.1	-0.3	1.2	-1.4	-1.5	-1.7	-1.6	-1.0	-1.2	-1.1	-1.6	-1.3	-1.1	-1.6	-1.5	-1.1	-0.6	-0.6	-2.2	-1.2	-2.1	-0.5
Hip circumference	1.1	4.6	16.2	4.0	1.5	2.2	1.3	1.2	-0.4	2.1	-0.4	2.2	1.0	3.0	3.0	3.1	-0.7	2.6	1.7	1.3	2.8	2.3	0.7	2.9	2.4	2.1	2.4
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.2	4.2	0.9	-1.5	0.1	-0.9	2.1	0.5	-0.4	-2.0	-0.7	-0.5	-0.4	-0.6	0.1	-1.0	-0.6	-1.7	-1.9	-1.3	-0.5	-0.9	-1.4	-0.7	-2.0	-0.7
Medication: Cholesterol lowering	1.1	1.7	4.9	-2.0	-1.1	-2.2	1.8	-1.2	-0.2	-1.0	1.1	-1.5	-0.8	-1.6	-2.1	-1.4	0.2	-1.0	-0.5	-0.5	-1.3	-1.4	-0.9	-0.0	-1.6	-0.1	-2.2
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	4.2	2.1	1.2	1.7	-1.4	0.7	0.5	1.7	-0.6	1.7	0.9	1.9	1.9	2.0	0.3	1.1	0.9	1.0	1.5	1.6	1.4	0.4	1.6	0.6	1.9
Birth weight	1.1	2.3	7.4	-0.4	1.8	2.0	-0.3	-1.8	0.6	1.8	1.9	0.8	1.1	1.6	0.5	0.5	1.2	1.7	1.6	2.7	1.9	1.5	2.5	0.8	1.8	1.4	1.7
Illnesses of siblings: Diabetes	1.1	1.3	7.2	-2.7	1.1	-0.8	1.1	-2.0	-0.9	-0.7	2.0	-0.8	-1.4	-1.4	-1.8	-1.1	-0.8	0.1	0.9	0.3	-0.0	-0.0	-0.2	0.9	-1.0	0.8	-1.1
Mineral and other dietary supplements	1.1	1.5	7.1	-2.7	-0.5	-1.6	0.0	-1.4	-0.9	-0.9	1.0	-1.1	-1.4	-1.5	-1.6	-1.5	-0.4	-1.5	-0.9	-0.4	-1.2	-0.2	-0.9	-1.2	-1.3	-1.0	-1.4
Alcohol drinker status: Previous	1.1	1.2	4.4	-1.2	-1.6	-1.5	-0.4	0.4	-0.3	-2.1	-0.8	-1.3	-0.2	-1.5	-1.2	-2.0	-0.7	-0.6	-0.7	-1.3	-1.7	-1.0	-0.4	0.2	-0.8	-0.4	-0.9
Schizophrenia (2018)	1.0	2.0	5.2	-0.8	-2.0	-2.0	0.4	1.2	0.3	-1.3	-1.4	-0.8	0.2	-1.5	-1.6	-1.4	-0.6	-1.8	-2.0	-1.5	-1.9	-2.3	-0.8	-2.0	-1.8	-1.4	-1.1
Alzheimer’s Disease (in mother)	1.0	1.2	3.6	-1.9	-1.5	-1.0	-0.8	0.3	0.8	-1.3	-0.4	-1.4	-0.9	-1.5	-1.5	-1.7	-0.7	-1.0	-0.9	-0.8	-1.4	-0.9	-0.7	-0.7	-0.6	-0.5	-1.0
Blood Platelet Count	1.0	11.7	28.3	0.7	3.4	1.9	1.0	-5.3	2.9	3.9	5.2	3.8	3.2	3.7	1.5	3.3	1.1	3.7	4.0	4.5	3.1	3.7	4.3	4.2	3.6	3.9	2.9
Smoking Status	1.0	2.4	7.4	2.7	1.0	0.6	0.9	-0.2	-0.8	2.3	0.6	1.9	0.3	2.1	2.0	2.5	1.0	1.7	1.7	1.6	1.4	1.3	2.0	1.9	1.1	1.9	0.9
Had other major operations	1.0	1.3	5.0	-0.6	-1.7	-0.9	-0.5	0.7	-0.0	-0.6	-1.0	-1.2	0.3	-1.0	-1.2	-0.7	0.4	-1.0	-1.1	-1.4	-2.1	-1.5	0.5	-2.2	-1.3	-1.5	-1.1
Time employed in main current job	1.0	1.1	4.4	-1.8	-0.9	-1.3	0.1	-0.3	0.7	-0.7	0.2	-0.8	-2.1	-1.2	-1.5	-1.0	-0.7	-1.2	-0.9	-0.7	-1.4	-0.5	-1.0	-0.9	-1.0	-0.8	-1.4
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	4.1	-0.5	-1.6	-1.5	0.4	0.8	-0.9	-2.0	-1.1	-1.0	-1.1	-1.1	-0.4	-1.1	-0.1	-1.2	-1.9	-1.9	-1.5	-1.3	-2.0	-1.0	-1.3	-1.5	-1.6
Tense / ‘highly strung’	1.0	1.7	4.2	0.7	-1.7	-0.7	1.2	2.1	-1.4	-1.6	-1.9	-1.0	0.0	-1.2	0.1	-0.9	-1.1	-1.3	-1.7	-1.9	-1.0	-0.7	-2.0	-1.3	-1.3	-1.5	-0.7
Age at first live birth	1.0	1.8	4.6	1.4	1.1	2.1	-1.0	-0.6	0.8	1.8	0.9	1.7	1.8	1.3	1.2	1.3	1.7	1.4	1.2	1.3	1.0	1.0	2.2	0.1	1.2	0.7	1.8
Medication for pain relief, constipation, heartburn	1.0	1.7	11.1	0.9	-1.3	-0.3	1.0	2.0	-0.3	-0.3	-2.4	-1.7	-0.8	-0.3	-0.6	0.1	-3.3	-1.4	-1.0	-1.6	-1.2	0.0	-0.6	-1.9	-0.7	-1.6	-0.1
Angina (self-reported)	1.0	1.3	3.6	-0.2	-1.6	-1.7	1.4	0.7	1.0	-0.8	-0.6	-1.0	-0.6	-1.5	-0.7	-0.9	0.5	-1.3	-1.1	-0.9	-1.3	-1.0	-1.0	-1.1	-1.9	-0.9	-1.9
Alcohol intake frequency.	1.0	2.2	7.1	-0.5	-1.7	-1.0	0.6	1.2	0.4	-2.7	-1.2	-0.7	-2.6	-2.1	-0.7	-2.3	-1.4	-0.6	-1.3	-1.9	-1.2	-1.6	-2.2	-0.5	-1.7	-1.2	-1.9
Comparative height size at age 10	1.0	5.6	21.3	4.6	1.9	2.6	0.9	1.1	0.3	3.1	-0.1	2.6	1.1	3.4	2.8	3.4	1.1	2.4	1.8	2.1	3.2	2.8	1.5	2.4	2.5	1.8	2.7
Hypertension (Self-reported)	1.0	2.9	7.2	-1.8	-1.8	-1.4	1.7	0.9	-1.2	-2.6	-1.3	-1.2	-0.7	-1.6	-1.1	-2.0	-0.8	-2.1	-2.6	-2.1	-2.1	-1.5	-2.7	-1.9	-0.8	-2.3	-0.6
Mood swings	1.0	1.8	4.8	1.2	-1.0	0.1	-0.6	2.0	-1.2	-1.6	-2.2	-0.4	-0.6	-0.3	0.8	-0.7	-0.1	-0.7	-2.1	-1.9	-0.6	-2.1	-1.9	-1.7	-1.2	-2.0	-1.2
Long-standing illness, disability or infirmity	1.0	1.5	3.1	-0.5	-1.8	-1.7	0.2	1.0	-1.5	-1.2	-1.0	-1.5	-0.7	-1.6	-1.5	-1.5	-0.1	-1.5	-1.2	-0.9	-1.6	-1.1	-0.6	-0.9	-1.6	-0.7	-1.6
Mouth/teeth dental problems: Mouth ulcers	1.0	1.5	3.0	0.6	1.5	0.8	-0.8	-1.3	0.9	1.4	1.4	1.2	1.5	1.3	1.2	1.3	0.8	1.3	1.4	1.7	1.3	1.3	1.2	1.5	1.7	1.5	0.9
Basal cell carcinoma (self-reported)	1.0	1.1	2.7	-0.6	-1.2	-0.1	0.9	1.6	-0.1	-0.9	-1.2	-0.6	0.3	-1.3	-0.6	-1.1	-1.3	-1.0	-1.2	-1.5	-1.6	-1.3	-1.1	-1.6	-1.1	-0.9	-0.7
Bipolar Disorder (2011)	0.9	0.9	2.5	0.2	-1.5	-0.8	-0.6	1.4	-0.9	-0.6	-1.6	-1.3	-0.1	-0.5	-1.0	-0.4	-0.8	-0.4	-1.3	-1.2	-1.3	-1.4	-0.8	-0.6	-0.5	-0.9	-0.7
LDL Cholesterol	0.9	1.4	3.5	-0.0	-1.2	-0.5	1.4	1.8	-0.3	-1.8	-1.9	-0.6	0.2	-0.8	-0.4	-1.5	-1.2	-0.5	-1.7	-1.6	-1.2	-1.1	-0.9	-1.5	-0.8	-1.8	-0.9
Waist Hip Ratio (WHR)	0.9	4.0	14.4	-3.8	-1.0	-2.5	-0.8	-1.6	-1.9	-2.4	0.8	-2.8	-1.8	-2.6	-3.2	-3.5	-1.6	-1.8	-1.6	-0.6	-1.8	-0.8	-1.4	-1.1	-1.9	-1.2	-2.0
Medication: Metformin	0.9	1.2	5.0	-0.9	1.2	0.7	0.2	-2.2	0.4	1.6	2.1	-0.1	0.8	0.8	-0.3	0.8	-0.4	1.3	1.5	1.6	0.4	-0.0	2.0	0.7	0.7	1.5	0.1
Hearing difficulty/problems with background noise	0.9	1.5	4.0	0.1	-1.9	-1.8	0.3	1.1	-0.9	-1.4	-1.4	-1.9	0.1	-0.7	-0.7	-1.0	0.4	-1.7	-1.2	-1.8	-2.0	-1.5	-0.3	-1.4	-1.1	-1.2	-0.5
Father’s age at death	0.9	1.2	3.8	0.7	1.5	1.7	0.5	-0.7	1.2	1.3	0.8	0.7	1.0	0.7	1.0	0.9	-1.5	0.8	1.1	1.2	1.3	2.0	1.0	0.7	0.5	1.0	0.9
Asthma	0.9	1.8	9.5	-1.7	-1.5	-3.1	1.3	-0.4	-0.7	-0.5	0.0	-1.6	-1.0	-1.2	-2.4	-1.2	-0.8	-1.5	-0.7	-0.3	-1.6	-1.8	-0.2	-0.2	-1.5	0.1	-1.8
Lung cancer (father)	0.9	1.1	3.6	-0.6	-1.9	-1.7	0.3	0.7	-1.5	-1.0	-0.9	-1.5	-0.1	-1.0	-1.5	-1.4	-0.4	-0.8	-1.2	-0.5	-1.2	-0.9	0.3	-0.6	-0.7	-0.9	-0.7
Breastfed as a baby	0.9	1.1	4.8	0.8	-1.2	-1.2	1.1	2.2	0.5	-0.9	-2.0	-0.6	-1.4	-0.4	0.0	-0.5	-0.5	-1.5	-0.6	-1.3	-1.0	-0.6	-0.7	-1.2	-0.6	-1.2	-0.7
Medication: Aspirin	0.9	1.2	3.3	0.3	1.4	0.5	0.6	-1.4	0.4	1.0	1.7	0.8	0.2	0.8	1.0	0.6	0.8	0.7	1.7	1.8	1.4	1.0	1.3	1.4	0.9	1.8	1.1
Arm fat percentage (left)	0.9	3.4	6.8	-2.0	-1.7	-2.3	2.3	0.2	-2.4	-2.0	-0.6	-2.3	-1.9	-1.9	-2.0	-1.9	-2.6	-1.8	-1.8	-1.8	-2.0	-1.7	-2.3	-1.1	-1.9	-1.2	-1.9
Friendships satisfaction	0.9	1.1	3.1	-0.6	-1.4	-0.7	1.2	1.2	-0.3	-1.3	-1.0	-1.8	-0.8	-1.1	-0.5	-1.4	-0.9	-1.5	-1.0	-1.1	-1.4	-1.3	-0.7	-0.6	-1.2	-0.4	-1.0
Eye problems/disorders: Cataract	0.9	1.1	3.7	1.5	1.9	0.2	-0.0	-0.5	0.2	1.1	0.8	1.1	-0.1	1.5	1.2	1.2	0.8	0.4	1.4	1.4	1.5	0.7	1.1	0.9	1.0	1.3	0.7
Vascular/heart problems diagnosed by doctor	0.9	2.4	6.3	1.8	1.6	1.6	-1.2	-0.5	0.9	2.5	0.7	0.9	1.1	1.7	1.0	2.2	-0.6	2.0	2.1	1.7	1.9	1.4	2.5	1.5	1.0	1.8	0.8
Depressed Affect (Nagel 2018)	0.8	1.6	6.0	0.4	-1.4	-1.2	0.6	1.4	-0.9	-2.1	-1.6	-0.5	-0.6	-0.9	0.1	-1.0	-1.2	-1.0	-2.0	-1.5	-0.7	-2.3	-2.4	-0.8	-1.1	-1.3	-1.2
Diabetes (mother)	0.8	1.0	4.7	-0.4	1.2	0.9	1.0	-2.1	-0.7	0.9	2.2	0.4	0.9	0.5	-0.4	0.4	0.0	1.4	1.1	1.0	0.5	1.4	0.5	1.5	0.2	0.9	-0.4
High blood pressure	0.8	2.3	7.0	-1.7	-1.4	-1.3	1.5	0.5	-1.5	-2.4	-0.9	-0.9	-0.8	-1.4	-0.9	-1.9	-0.3	-1.8	-2.3	-1.9	-1.9	-1.3	-2.6	-1.6	-0.7	-2.0	-0.5
Chronic bronchitis/emphysema (father)	0.8	1.0	4.5	0.5	0.6	0.9	-2.1	-1.0	1.9	1.3	1.1	1.0	0.9	0.6	1.0	1.1	1.9	0.6	0.4	0.6	0.6	1.3	0.5	-0.1	0.3	0.2	0.5
Impedance of arm (left)	0.8	3.9	12.0	-3.5	-1.1	-2.2	0.8	-0.5	0.3	-2.1	-0.1	-1.5	-0.7	-3.0	-2.3	-2.3	-0.4	-2.3	-1.8	-1.6	-2.0	-3.0	-1.5	-3.2	-2.5	-1.9	-2.2
Leg fat percentage (right)	0.8	2.9	6.2	-1.4	-1.9	-2.0	2.4	0.5	-2.0	-2.5	-0.9	-2.3	-2.4	-1.9	-1.3	-2.1	-1.9	-1.6	-1.6	-1.7	-1.7	-1.6	-2.2	-0.5	-1.3	-0.9	-1.3
Neck or shoulder pain in last month	0.8	1.1	5.7	1.0	0.9	0.1	2.3	-0.1	0.5	-0.3	0.9	1.7	1.2	0.0	1.4	0.0	2.4	0.4	0.8	0.6	0.7	-0.3	-0.5	1.6	0.5	1.3	0.3
Chest pain or discomfort	0.8	1.1	2.9	-0.0	-0.9	-1.6	-0.2	0.7	-0.9	-1.7	-1.1	-1.0	-0.6	-0.7	-0.3	-0.8	0.2	-1.0	-1.2	-1.7	-1.2	-1.5	-1.6	-0.7	-1.2	-1.3	-1.2
Age at last live birth	0.8	1.2	7.6	1.3	0.8	1.5	-1.0	-0.4	1.1	1.9	0.5	1.6	2.8	1.0	0.9	1.5	1.0	0.8	0.4	0.8	0.5	0.2	1.1	-0.7	0.5	0.1	0.8
Asthma (self-reported)	0.8	1.7	8.8	-1.7	-1.5	-3.0	1.6	-0.4	-0.3	-0.6	0.1	-1.6	-1.0	-1.2	-2.2	-1.2	-0.9	-1.3	-0.6	-0.2	-1.4	-1.7	-0.2	-0.0	-1.3	0.3	-1.7
Osteoporosis (self-reported)	0.8	1.0	3.9	-2.0	-0.5	-1.5	0.4	-1.0	-0.4	-0.9	0.5	-1.4	-0.9	-1.3	-1.4	-1.3	-0.2	-0.7	-0.5	-0.3	-1.1	-1.6	-0.5	-0.8	-0.8	-0.3	-1.5
Medication: Atorvastatin	0.8	1.0	2.7	-1.5	-1.1	-0.3	-1.4	-0.1	-1.1	-1.5	-0.7	-1.0	1.2	-0.7	-1.1	-1.6	-1.5	-0.4	-1.0	-0.7	-0.8	-0.4	0.1	-1.1	-0.2	-1.5	-0.1
Myopia	0.8	1.1	8.0	0.4	1.0	-0.2	0.5	-0.5	2.8	0.7	1.1	2.0	-0.3	0.0	0.3	1.0	1.3	0.4	1.1	0.9	0.9	1.2	-0.5	1.5	0.4	1.4	0.4
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.3	1.2	1.3	1.4	-0.0	-0.7	0.9	1.2	1.0	0.7	0.5	1.1	1.5	1.2	0.6	0.8	1.1	1.0	0.8	1.1	0.8	0.7	0.9	1.3	1.0
Medication: Atenolol	0.7	0.8	2.6	-0.5	-1.1	-0.8	0.1	0.4	1.2	-1.6	-0.4	-0.8	-0.4	-1.3	-0.3	-1.4	0.9	-0.7	-0.6	-1.3	-0.9	-0.9	-1.4	-0.4	-0.9	-0.7	-1.0
Hair/balding pattern: Pattern 2	0.7	0.9	2.3	0.7	-0.8	-0.9	0.5	1.3	-1.4	-1.0	-1.2	-0.1	-1.1	-0.9	-0.4	-0.2	-0.4	-1.2	-0.9	-1.4	-0.7	-1.2	-1.1	-1.5	-0.9	-0.8	-0.2
Had menopause	0.7	0.9	6.9	-0.9	-1.1	-0.6	-0.5	0.5	-2.6	-0.7	-0.5	-1.6	-0.6	-1.4	-0.9	-1.3	-1.9	-0.5	-0.1	-0.4	-0.6	-0.3	0.3	-0.0	-0.6	0.1	-0.0
Number of live births	0.7	0.9	3.5	0.1	1.5	-0.6	0.5	-1.7	1.4	1.3	1.9	0.8	0.3	0.7	0.2	0.9	1.6	-0.1	1.2	1.1	0.5	0.0	0.7	0.9	0.2	1.4	0.2
Pulse wave Arterial Stiffness index	0.7	0.8	3.4	-1.5	-0.5	-1.0	0.8	-0.3	-1.8	-1.3	0.2	-1.2	0.3	-1.0	-1.0	-1.3	-1.1	-1.4	-0.3	-0.4	-0.6	-0.3	-0.7	-0.6	-0.3	-0.1	0.4
Medication: Paracetamol	0.7	1.2	4.6	-1.5	1.2	-0.3	-1.2	-2.2	-0.9	-0.1	2.1	0.3	1.1	-0.3	-0.2	-0.6	1.8	1.1	1.1	1.4	0.8	-0.3	0.6	1.5	0.0	1.5	-0.6
Worry too long after embarrassment	0.7	1.3	3.2	-0.8	-0.9	-1.1	0.3	0.8	-0.4	-1.0	-0.8	-1.7	-0.5	-1.7	-1.2	-1.0	-1.6	-1.7	-0.7	-1.2	-1.2	-1.0	-1.1	-1.4	-1.8	-0.4	-1.3
Medication: Omeprazole	0.7	0.8	2.9	-1.4	-0.8	-1.3	-0.7	-0.7	-0.1	-1.1	0.2	0.1	-0.3	-0.8	-1.5	-1.0	-0.1	-0.7	-1.0	-0.8	-0.9	-0.3	-0.7	-1.0	-0.9	-1.3	-1.7
Medication: Seretide 50 evohaler	0.7	0.8	4.3	-0.9	-1.3	-2.1	0.2	0.2	0.4	-0.8	-0.4	-0.6	-1.3	-0.6	-1.3	-0.4	0.1	-0.8	-0.6	-0.6	-0.5	-1.9	-0.8	0.2	-0.7	-0.1	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.9	3.2	-1.5	-0.7	-1.5	0.5	-0.6	1.8	-0.4	0.4	-0.3	0.3	-1.0	-1.3	-0.6	0.1	-0.5	-1.5	-0.3	-0.8	-0.8	-1.1	-0.2	-1.2	-0.8	-1.4
Average weekly red wine intake	0.7	1.1	5.0	-0.5	0.6	0.1	-1.4	-1.4	-0.1	1.9	1.6	0.0	0.4	0.7	-0.6	0.9	1.7	0.7	0.7	1.6	-0.0	-0.3	2.2	0.7	0.8	1.4	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	5.4	-0.4	2.3	1.4	-0.4	-2.0	-0.5	1.0	1.9	1.1	-1.0	1.0	0.4	0.8	-0.2	1.3	1.3	1.8	1.8	0.8	0.7	0.8	1.3	1.3	1.3
Wears glasses or contact lenses	0.7	0.8	5.8	-0.3	0.5	0.3	1.5	0.1	-2.4	-0.3	0.5	-0.0	-0.2	-0.2	0.5	-0.6	-1.3	0.4	0.8	0.7	0.9	1.1	-0.1	1.7	0.8	1.3	1.1
Medication: Paracetamol	0.7	1.1	4.2	-1.5	0.8	-0.6	-1.0	-2.1	-1.4	-0.3	1.8	-0.2	0.5	-0.6	-0.5	-0.8	1.0	1.2	1.0	1.3	0.6	-0.7	0.5	1.5	-0.1	1.3	-1.0
Leg fat percentage (left)	0.7	2.6	5.7	-1.1	-2.0	-2.0	2.2	0.6	-1.8	-2.3	-0.9	-2.0	-2.4	-1.8	-1.2	-1.9	-1.7	-1.4	-1.4	-1.7	-1.7	-1.6	-2.0	-0.3	-1.4	-0.7	-1.4
Supplements: Calcium	0.7	0.8	4.4	0.3	-0.3	0.1	0.4	1.2	-0.7	-1.4	-1.1	-1.4	-1.4	-0.9	-0.0	-0.8	-2.1	-0.6	-0.8	-1.2	-0.5	-0.7	-1.1	-0.6	-0.7	-0.5	-0.3
Alzheimer’s Disease (including proxy)	0.6	0.9	3.7	-1.9	-1.1	-0.6	-1.0	-0.4	1.2	-1.5	0.1	-0.9	-0.6	-1.3	-0.7	-1.6	-0.6	-0.9	-0.3	-1.0	-1.3	-0.8	-0.3	-0.7	-0.5	-0.3	-0.5
Ever used hormone-replacement therapy (HRT)	0.6	0.7	3.9	-1.2	-0.7	-0.6	-0.7	-0.3	-2.0	-0.8	-0.0	-1.6	-1.0	-1.0	-0.7	-1.2	-1.6	-0.1	0.0	-0.2	-0.7	-0.5	0.4	0.6	-0.4	0.3	-0.5
Impedance of leg (right)	0.6	2.7	7.3	-2.3	-1.4	-1.6	0.0	0.3	0.9	-2.6	-0.9	-1.1	-1.3	-2.7	-1.1	-2.5	0.4	-1.9	-1.8	-1.5	-1.5	-2.2	-1.6	-2.1	-1.7	-1.9	-1.3
Townsend deprivation index at recruitment	0.6	0.8	4.2	0.5	-0.9	-0.3	2.1	1.1	-0.3	-0.3	-0.4	-1.4	-0.8	-1.0	0.4	0.0	-1.1	-0.8	0.3	-1.3	-1.0	-0.6	-1.1	-0.2	-1.2	0.4	-1.4
Relative age voice broke	0.6	1.0	4.8	2.2	0.0	1.2	-0.1	1.0	0.3	0.7	-0.9	0.5	0.8	1.3	1.2	1.1	-0.7	1.2	0.8	0.4	0.9	1.2	1.2	0.8	1.4	0.4	1.3
Qualifications: CSEs or equivalent	0.6	0.8	2.9	-0.0	-0.5	-0.7	1.4	1.0	0.1	-1.1	-1.0	-0.2	0.4	-0.7	-0.2	-0.4	-0.6	-1.7	-1.0	-1.4	-1.1	-0.5	-1.6	-1.0	-0.5	-1.1	-0.1
Ever highly irritable/argumentative for 2 days	0.6	0.7	2.9	1.0	-0.9	-0.8	-1.0	1.4	-0.2	-0.6	-1.7	-1.0	-1.4	0.5	0.3	0.2	-0.7	-1.0	-0.6	-1.3	-0.9	-0.6	-0.3	-0.8	0.0	-0.7	0.3
Medication: Ventolin 100micrograms inhaler	0.6	0.7	2.7	-0.8	-0.7	-1.3	0.9	0.3	-0.5	-0.4	-0.6	-1.2	-1.5	-0.5	-1.4	-0.8	-1.0	-0.5	-0.7	-0.5	-1.0	-1.6	0.1	-0.6	-0.7	-0.4	-1.1
Body fat percentage	0.6	2.3	4.3	-1.3	-1.6	-1.9	2.1	0.2	-1.9	-1.9	-0.5	-1.9	-1.8	-1.6	-1.3	-1.5	-1.8	-1.3	-1.5	-1.5	-1.5	-1.7	-2.0	-0.6	-1.4	-0.8	-1.5
Medication: Allopurinol	0.6	0.8	3.1	0.3	-1.6	-0.7	-0.9	1.3	-1.1	-0.9	-1.6	-0.0	-0.2	0.1	-0.3	-0.6	0.2	-0.2	-1.3	-1.0	-1.0	-0.3	-0.5	-1.1	0.0	-1.8	-0.7
Had major operations	0.6	0.7	3.5	0.5	-0.9	0.2	-0.6	1.9	-1.6	-0.9	-1.8	-0.7	-0.6	-0.5	-0.1	-0.9	-1.1	-0.5	-0.3	-0.6	-0.3	0.1	-0.0	-0.6	0.0	-0.7	-0.0
Illness, injury, bereavement, stress in last 2 years	0.6	0.8	2.6	-0.5	1.0	0.3	-1.2	-1.5	-1.0	1.1	1.1	0.4	1.6	0.7	-0.2	0.3	-0.3	0.8	0.6	1.5	0.6	0.1	1.6	0.1	0.8	0.8	0.3
Ever had bowel cancer screening	0.6	0.7	4.5	-2.1	-0.7	-0.9	0.0	-1.0	-0.4	-0.1	0.9	-1.0	-0.6	-0.8	-1.4	-0.9	0.3	-0.5	-1.2	0.6	-0.4	-1.4	-0.5	-0.5	0.0	-0.2	0.3
Medication: Gliclazide	0.6	0.7	4.7	-1.5	0.4	-0.3	0.6	-2.2	-0.4	1.2	1.8	-0.9	0.2	-0.3	-1.3	0.5	0.2	0.1	0.1	0.5	-0.6	0.2	0.2	-0.6	-0.4	-0.5	-1.1
Hearing aid user	0.6	0.6	2.4	-0.3	0.6	0.6	-0.7	-1.0	0.7	0.7	0.9	1.0	-0.5	0.6	0.3	0.3	0.7	1.1	1.1	1.1	0.8	0.4	1.6	0.8	0.8	0.9	0.5
Impedance of whole body	0.6	3.2	8.7	-3.0	-1.2	-2.0	0.2	-0.3	1.1	-2.2	-0.3	-1.0	-0.8	-2.9	-1.7	-2.3	0.6	-2.0	-1.8	-1.5	-1.8	-2.8	-1.5	-2.5	-2.2	-1.8	-1.9
Triglycerides	0.5	0.9	3.1	-0.2	-0.5	-0.2	-0.4	1.6	-0.7	-1.8	-1.5	-0.6	0.5	-1.0	-0.5	-1.6	-0.9	-0.7	-1.1	-1.2	-0.5	-0.4	-1.1	-1.1	-0.7	-1.2	-0.0
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.7	-1.1	-0.9	-0.7	0.7	0.1	0.0	-1.6	-0.4	-0.8	-0.9	-1.2	0.0	-1.2	-0.4	-1.2	-0.9	-0.8	-0.7	-0.3	-1.1	-0.8	-0.5	-0.6	-0.3
Systolic blood pressure, automated reading	0.5	1.4	4.1	0.0	-1.7	-1.1	-0.6	1.3	-0.5	-1.2	-1.4	-0.0	-0.4	-0.9	-0.4	-0.5	0.9	-1.0	-1.9	-2.0	-1.9	-0.6	-1.7	-0.8	-1.1	-1.6	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	2.4	-0.6	-0.0	-1.3	1.5	-0.4	-0.9	-1.5	-0.2	-0.9	-0.8	-0.9	-0.2	-0.8	-1.2	-1.1	-0.4	-0.9	-0.5	-0.8	-1.2	-0.1	-0.7	0.1	-0.3
Alcohol usually taken with meals	0.5	0.9	8.0	-0.1	0.7	1.2	-2.8	-0.5	0.2	1.1	0.6	-0.1	0.4	0.8	0.2	0.5	0.3	0.5	0.9	1.0	0.5	0.5	1.5	0.1	1.3	0.5	1.4
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.7	1.2	-0.9	0.3	-1.6	1.6	-0.1	-0.7	-1.6	-0.3	-1.0	0.1	0.2	-0.3	-1.3	0.3	-0.5	-0.5	0.0	-0.0	-0.3	0.2	0.3	-0.3	0.2
Arm fat percentage (right)	0.5	1.8	4.5	-1.6	-1.1	-1.6	2.0	-0.3	-2.1	-1.4	-0.1	-1.7	-1.2	-1.2	-1.4	-1.2	-1.9	-1.2	-1.4	-1.2	-1.4	-1.1	-1.7	-0.6	-1.2	-0.8	-1.4
Hair/balding pattern: Pattern 3	0.5	0.7	6.4	0.3	-0.9	-0.2	-2.5	0.6	0.9	-0.1	-0.7	-0.5	-1.7	0.3	-0.7	-0.8	0.2	0.8	-0.9	0.2	-0.2	-0.2	0.6	0.2	-0.1	-1.0	-0.9
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	3.2	1.6	-0.1	0.0	-0.9	1.8	0.0	-0.3	-1.3	1.1	-0.2	1.0	0.8	0.4	1.0	0.4	-0.1	-0.2	0.6	-0.4	-0.3	0.8	0.9	0.2	0.5
Exposure to tobacco smoke at home	0.5	0.6	2.6	0.8	-0.1	-0.1	-0.3	1.2	1.6	-0.9	-1.1	1.3	-1.2	-0.2	1.3	-0.1	-0.3	-0.5	0.1	-0.8	-0.1	1.1	-0.5	0.0	0.5	-0.3	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	7.5	-0.6	-0.1	-0.9	-2.7	-0.5	1.2	-0.0	0.0	-0.4	-0.7	0.0	-0.5	-0.0	0.6	0.3	0.2	0.4	0.1	-0.9	0.4	0.8	0.1	0.8	-0.6
Medication for cholesterol	0.5	0.7	3.1	1.7	0.7	1.0	-0.6	0.6	0.9	1.4	-0.4	0.6	-0.1	1.5	0.5	1.8	-0.3	1.0	0.7	0.2	1.1	0.5	0.7	0.2	0.6	0.4	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.5	2.5	-1.6	-0.1	-0.4	0.6	-1.1	-1.2	-0.4	0.9	-0.9	-1.6	-0.4	-0.8	-1.1	-0.6	-0.3	-0.5	0.6	-0.5	-0.5	0.2	-0.3	0.1	0.1	-0.0
Osteoarthritis (self-reported)	0.5	0.7	8.6	-0.2	0.2	0.0	-0.0	-0.7	-2.9	-0.8	0.3	-0.9	0.4	-0.3	-0.2	-0.8	-2.1	0.0	0.0	0.1	0.2	-0.6	0.2	-0.3	-0.2	0.2	-0.3
Average weekly champagne plus white wine intake	0.5	0.7	5.7	-0.4	0.6	0.7	-2.4	-0.4	1.4	0.7	0.0	0.3	0.7	1.3	0.3	0.5	-0.2	0.7	0.3	0.8	0.7	0.6	1.0	-0.1	1.3	0.0	1.3
Medication: Lisinopril	0.5	0.7	3.1	-0.1	0.4	-0.8	1.8	-0.4	-1.1	-0.5	0.3	0.1	-0.9	-0.4	-0.5	-0.0	-0.5	-1.0	-0.6	-0.8	-0.6	-0.7	-1.7	-1.1	-0.9	-0.8	-1.0
Age started oral contraceptive pill	0.5	0.7	3.3	-0.1	-0.8	-0.2	-1.2	0.8	-1.8	-0.6	-1.2	-1.1	-0.5	-0.7	-0.7	-0.7	-0.9	-0.1	-0.3	-1.0	-1.1	-0.5	0.8	-0.7	-0.7	-0.7	-0.7
Ever depressed for a whole week	0.5	0.6	2.2	-0.8	-0.8	-0.8	-0.5	0.2	0.3	-0.8	-0.3	-1.0	-1.4	-1.1	-0.9	-1.1	-1.1	-0.3	-0.6	-0.1	-0.0	-1.5	-0.7	-0.3	-0.5	0.1	-0.5
Prostate Cancer	0.4	0.5	4.7	0.4	0.2	0.2	2.2	0.8	0.1	-0.1	-0.1	0.1	-1.7	-0.7	0.1	-0.3	0.0	-1.3	-0.2	-0.1	-0.0	0.4	-0.6	-1.1	-0.7	-0.3	0.0
Primary Biliary Cirrhosis	0.4	0.5	2.8	0.8	0.2	0.5	0.1	0.3	1.7	0.9	-0.3	1.4	0.8	0.8	1.2	1.0	0.7	0.3	0.4	0.3	0.4	0.7	0.7	0.3	0.8	0.1	0.9
Type 2 Diabetes (T2D) (2018)	0.4	0.7	5.0	-1.0	-0.5	-0.8	-1.3	-0.2	-2.2	-0.5	0.0	-1.2	-0.7	-0.5	-0.8	-0.7	-0.7	-0.6	-0.6	-0.4	-1.1	-1.3	-0.2	-0.8	-0.7	-0.0	-0.6
Lung FVC	0.4	2.1	5.6	-2.3	-0.9	-0.6	-0.0	0.1	-2.4	-1.7	-0.6	-2.2	-2.2	-1.7	-2.0	-2.2	-2.1	-0.8	-1.1	-0.6	-0.7	-1.6	-0.8	-1.4	-1.0	-1.4	-0.7
Chronotype (morning person)	0.4	1.0	2.5	-0.9	-0.7	-1.4	-1.6	0.2	0.7	-1.2	-0.5	-0.8	-1.1	-1.0	-0.8	-1.0	-0.4	-1.4	-0.8	-1.1	-1.3	-1.2	-1.2	-0.6	-1.2	-0.5	-1.5
Average weekly spirits intake	0.4	0.5	3.5	0.4	-0.8	-0.5	-0.3	1.3	-0.1	-1.3	-0.9	-0.2	-1.9	-0.8	-0.2	-1.2	-0.2	-0.6	-0.8	-0.4	-0.0	-0.6	-0.7	0.4	-0.5	-0.0	0.1
Medication: Co-codamol	0.4	0.5	2.2	-0.9	-0.2	-0.4	1.1	-0.8	1.5	-0.5	0.9	-0.2	0.4	-0.6	-0.7	-0.8	0.8	0.1	0.0	-0.1	-0.3	-0.7	-0.2	0.1	-0.9	0.2	-1.3
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	2.5	1.6	-0.2	-0.1	-0.6	1.2	-1.0	0.7	-1.0	0.0	-0.1	1.3	0.6	1.1	-0.6	0.4	-0.2	0.1	0.1	-0.3	0.3	0.5	0.8	0.1	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.8	2.7	-0.4	-1.2	-1.0	0.3	1.1	0.1	-0.4	-0.6	-0.9	-1.5	-0.9	-1.6	-0.7	-0.9	-0.8	-0.9	-0.8	-1.0	-0.6	-1.1	-0.3	-1.2	-0.5	-1.4
Hayfever, allergic rhinitis or eczema	0.4	0.8	1.8	-0.8	-0.6	-0.9	1.3	0.3	0.5	-0.5	-0.5	-0.3	-0.4	-1.0	-1.2	-0.5	-0.6	-1.1	-1.4	-1.1	-1.3	-1.0	-1.1	-1.2	-0.9	-1.0	-1.0
Multivitamins +/- minerals	0.4	0.6	2.8	1.7	-0.2	0.5	0.5	1.4	0.0	-0.2	-1.2	1.0	-0.2	0.8	1.1	0.9	0.4	0.2	-0.3	-1.1	-0.2	0.9	-0.3	-0.1	0.5	-0.4	1.0
Impedance of leg (left)	0.4	2.1	6.2	-2.1	-1.4	-1.5	0.1	0.1	1.4	-2.2	-0.7	-0.6	-1.2	-2.5	-0.9	-2.1	0.6	-1.5	-1.4	-1.3	-1.4	-2.1	-1.2	-1.7	-1.5	-1.4	-1.2
Qualifications: None of the above	0.4	0.9	4.2	-1.8	-0.4	-1.2	2.0	-2.1	0.7	-0.8	1.5	-0.5	-0.6	-0.6	-0.5	-1.1	0.5	0.3	0.8	0.7	-0.4	-0.2	0.3	0.4	-0.1	0.7	-1.3
Impedance of arm (right)	0.4	1.9	7.7	-2.8	-0.3	-1.2	0.1	-1.0	0.6	-1.3	0.4	-0.8	-0.0	-2.1	-1.4	-1.6	0.4	-1.5	-1.3	-0.9	-1.3	-2.1	-0.8	-2.5	-1.7	-1.4	-1.3
Birth weight of first child	0.4	0.7	5.3	1.4	-0.2	-1.0	0.8	0.8	0.2	0.2	-0.2	1.2	-0.7	0.6	0.5	1.1	2.3	-0.4	-0.4	-0.4	-0.1	0.1	-1.4	-0.3	0.0	-0.8	-0.4
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	5.7	0.9	-0.1	0.7	-0.2	1.0	-2.4	0.1	-1.0	-0.0	0.2	0.5	0.2	0.4	-1.2	-0.0	-0.7	-0.5	-0.3	-0.5	0.3	-0.3	0.8	-0.3	1.4
Number of full brothers	0.4	0.5	1.3	0.4	0.4	0.5	-0.3	-0.6	1.1	1.1	0.7	0.2	0.6	1.1	0.6	0.8	1.0	0.7	0.7	0.7	0.2	0.1	0.5	1.1	0.7	0.8	0.2
Medication: Ibuprofen	0.4	0.5	2.9	1.5	-0.3	0.6	-0.7	1.7	0.3	-0.3	-1.2	0.7	0.3	0.7	0.8	0.2	0.8	0.7	-0.2	-0.3	0.4	-0.7	-0.4	0.4	0.7	-0.1	0.1
Miserableness	0.4	0.7	3.5	0.9	-0.2	-0.9	1.2	0.9	-0.7	-1.0	-0.9	0.2	-0.7	-0.3	0.6	-0.1	-0.6	-0.7	-1.0	-0.9	-0.3	-1.2	-1.9	0.1	-0.7	-0.3	-0.8
Mother’s age at death	0.4	0.5	3.4	-0.5	0.1	0.0	-1.3	-1.1	-0.1	0.5	0.6	-0.1	1.3	0.8	-0.3	0.2	0.4	0.7	0.5	0.8	0.5	0.3	1.8	-0.2	0.8	0.1	0.9
Irritability	0.4	0.7	6.1	1.7	-0.0	0.3	-0.3	0.9	-2.5	0.1	-0.6	0.2	0.1	0.6	1.0	0.9	0.5	0.2	-0.4	-1.1	-0.3	-0.6	-0.7	-0.7	-0.5	-0.6	-0.7
Schizophrenia vs Biploar Disorder	0.3	0.4	2.4	-1.4	0.8	-0.3	-0.1	-1.6	-0.4	-0.2	1.2	0.3	0.0	-0.6	-0.3	-0.8	0.3	-0.5	-0.0	0.9	0.6	-0.3	-0.1	-0.3	-0.4	0.1	-0.1
Alzheimer’s Disease (in father)	0.3	0.4	1.5	-1.2	-0.3	-0.2	-1.2	-0.8	0.1	-1.1	0.4	-0.4	-0.3	-0.2	0.2	-0.6	-0.8	-0.4	0.5	-0.7	-0.6	0.2	0.7	-0.3	0.2	0.1	0.9
Crohns Disease (2017)	0.3	0.6	2.3	-0.0	-0.3	-1.1	-1.5	0.6	-1.1	-0.8	-0.8	-0.6	-0.4	-0.1	-0.8	-0.2	-0.8	-0.8	-0.5	-1.1	-0.8	-1.1	-1.2	-0.6	-0.6	-0.6	-1.0
Irritable Bowel Disease (IBD)	0.3	0.8	4.5	-0.3	-0.2	-1.0	-2.1	0.8	-1.5	-1.4	-0.8	-0.3	0.4	-0.8	-0.7	-0.9	-0.9	-0.9	-0.4	-1.0	-0.6	-0.4	-1.4	-0.3	-0.8	-0.5	-0.9
Ulcerative Colitis (UC)	0.3	0.5	3.4	0.5	0.4	0.1	-1.9	0.9	-1.0	-0.9	-0.7	0.8	1.2	-0.5	0.5	-0.7	-0.2	0.0	0.1	-0.1	0.5	0.7	-0.7	0.6	0.1	0.2	0.2
Crohns Disease (2012)	0.3	0.4	2.0	0.6	0.8	0.0	-0.4	-0.3	-0.3	0.5	0.1	0.1	1.4	1.3	-0.2	0.9	-1.0	0.7	0.9	0.2	0.2	0.1	0.6	0.6	0.8	0.7	0.4
Blood Red Count	0.3	3.4	7.9	-2.1	-1.0	-1.0	0.3	1.2	-2.2	-2.5	-2.2	-1.7	-0.4	-1.8	-1.9	-2.1	-1.7	-2.7	-2.6	-2.1	-1.5	-0.8	-2.3	-2.8	-1.0	-2.8	0.5
Systolic Blood Pressure	0.3	1.5	6.2	0.2	-1.2	-0.9	-1.7	1.3	-0.5	-1.5	-1.5	0.0	-0.6	-0.7	0.0	-0.3	1.4	-1.3	-1.9	-2.0	-1.1	-0.2	-2.5	-0.7	-0.9	-1.9	-0.9
Hypothyroidism (self reported)	0.3	0.7	2.3	0.4	0.9	0.5	1.5	-1.1	0.9	0.8	1.5	0.7	0.4	0.2	0.7	0.7	1.2	0.6	1.3	0.9	0.5	0.6	0.3	1.2	0.5	1.5	0.0
Respiratory disease	0.3	0.7	3.3	0.3	0.4	-0.4	1.8	-0.4	-0.2	0.7	0.4	0.6	0.3	1.0	0.7	0.6	-0.6	0.8	1.0	1.0	0.8	0.5	0.7	1.6	1.0	1.4	0.8
Hearing difficulty/problems: Yes	0.3	0.5	1.8	0.4	-0.7	-1.1	0.5	-0.0	-0.8	-0.3	-0.3	-1.4	-1.1	-0.3	-0.2	-0.1	-0.8	-0.6	-0.3	-0.9	-1.1	-0.8	0.6	-0.9	-0.9	-0.3	-0.0
Trunk fat percentage	0.3	1.3	3.3	-0.8	-1.1	-1.6	1.8	0.1	-1.5	-1.4	-0.4	-1.4	-1.5	-1.1	-0.8	-0.9	-1.7	-0.9	-1.1	-1.1	-1.0	-1.4	-1.6	-0.2	-1.0	-0.4	-1.1
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.6	0.6	-0.3	0.4	-0.1	0.9	1.1	-0.5	-1.3	-0.3	0.3	0.2	0.6	0.0	-0.9	0.2	-0.6	-0.9	-0.7	-0.5	-0.0	-0.3	-0.1	-0.4	-0.3
Supplements: Glucosamine	0.3	0.3	1.6	1.1	-0.4	0.3	0.8	1.3	-0.2	0.4	-1.0	0.1	0.4	0.3	0.0	0.1	-0.9	0.5	0.2	0.5	0.5	-0.6	0.6	0.4	0.4	0.4	0.2
Medication: Levothyroxine sodium	0.3	0.5	2.7	-0.2	0.7	0.0	-0.2	-1.2	1.6	0.7	1.3	0.5	0.3	0.1	0.0	0.5	1.3	0.5	0.6	0.6	-0.1	0.6	0.3	0.5	0.1	0.5	-0.6
High blood pressure (mother)	0.3	0.4	1.8	0.6	-0.2	0.3	-1.4	0.9	0.7	0.1	-0.9	0.9	0.1	0.4	0.5	0.4	0.6	-0.1	-0.6	-0.2	-0.0	0.9	-0.7	-0.2	0.6	-0.9	0.5
Number of incorrect matches in round	0.3	0.6	4.0	-0.4	-0.7	-0.8	2.0	0.3	-1.4	-0.9	-0.0	-0.9	0.3	-1.1	-0.8	-0.5	-1.0	-0.5	0.4	-0.7	-0.6	-0.4	0.0	-0.1	-0.6	0.6	0.0
Heart attack	0.3	0.4	2.9	0.7	-0.3	-0.4	1.0	0.7	0.4	-0.7	-0.3	0.1	-0.7	-0.1	0.3	-0.7	1.5	-0.2	0.2	-0.2	-0.4	-1.7	0.6	-0.1	-0.5	0.5	-0.5
Pain all over the body in last month	0.3	0.3	1.2	0.8	0.7	0.6	-0.9	-0.4	0.2	0.3	0.4	0.7	0.2	0.8	0.9	0.7	1.1	0.1	0.8	0.4	0.7	0.7	0.3	-0.2	0.5	0.2	0.2
Alcohol intake versus 10 years previously	0.3	0.5	2.1	1.1	-0.6	-0.1	-0.3	1.1	0.7	-0.5	-0.6	0.5	-1.0	-0.7	0.4	-0.3	0.4	-0.2	-1.0	-0.4	0.1	-1.0	-1.4	-0.0	-0.7	-0.3	-0.7
Medication: Lansoprazole	0.3	0.3	1.7	-0.5	-0.7	-0.1	1.3	0.1	0.5	0.2	0.3	-0.3	-0.2	-0.6	-0.1	0.0	1.2	-0.1	-0.3	-0.2	-0.9	-0.8	-0.7	-0.6	-0.6	-0.2	-1.0
Illnesses of mother	0.3	0.4	1.2	-0.4	0.8	0.2	0.2	-0.7	0.5	0.9	0.6	-0.1	0.9	0.4	0.0	0.3	-0.1	0.5	0.7	1.0	0.9	-0.1	0.8	0.7	0.3	1.1	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	2.2	-1.2	-0.7	0.2	1.0	0.2	0.6	-1.5	-0.3	-0.4	-0.9	-1.2	-0.3	-1.5	0.2	-0.2	-0.4	-0.6	-0.4	-0.4	-0.9	0.1	-0.6	-0.1	-0.8
Hair/balding pattern: Pattern 4	0.3	0.8	3.4	-1.4	0.3	-1.3	1.5	-1.3	-1.8	-0.2	0.8	-0.7	0.7	-0.5	-1.1	0.4	-1.3	-1.2	0.3	-0.3	-0.5	-0.4	-0.8	-0.3	-0.2	0.4	0.1
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.5	-0.8	0.6	-1.2	0.9	-0.9	0.7	-0.5	0.8	-0.4	-0.2	0.1	-0.5	-0.3	-0.9	-0.7	-0.3	0.1	-0.1	-0.9	-0.9	0.7	-0.1	0.6	-0.4
Headache pain in last month	0.3	0.5	1.6	0.8	0.1	0.8	0.1	-0.0	-0.3	0.2	-0.0	0.5	1.1	1.0	1.1	0.6	1.3	0.9	0.9	0.3	0.5	0.4	1.1	0.4	1.1	0.5	0.9
Glaucoma (self-reported)	0.3	0.4	1.1	0.0	0.7	0.3	0.5	-0.6	0.5	0.7	0.7	0.5	0.8	0.2	0.3	0.5	-0.7	0.5	0.6	0.8	0.6	1.0	0.5	1.0	0.4	0.9	0.4
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	2.8	-0.3	0.9	0.2	0.9	-1.5	0.4	0.8	1.7	0.5	0.8	0.1	0.2	0.6	1.3	0.5	1.1	0.9	0.2	0.5	0.4	0.8	0.5	1.1	-0.1
Family relationship satisfaction	0.3	0.3	1.4	-0.6	-1.2	-0.5	0.4	1.0	0.8	-0.8	-0.9	-0.3	0.2	-0.4	-0.4	-1.1	0.3	-0.4	-0.7	-0.1	-0.6	0.3	0.2	0.3	0.1	-0.3	-0.1
Illnesses of father: Heart disease	0.3	0.4	1.3	0.7	-0.7	-0.1	0.8	1.0	-0.3	-0.5	-1.0	0.4	-0.2	0.5	0.8	0.0	0.8	0.8	0.7	-0.5	-0.3	0.0	1.1	0.8	0.7	0.4	0.2
Back pain experienced in last month	0.3	0.4	1.3	0.1	0.3	0.7	0.2	-0.4	1.2	0.1	0.6	1.1	0.5	0.5	0.8	-0.1	1.0	1.1	0.1	0.6	0.1	0.0	0.8	1.1	0.7	0.9	0.2
Pain type(s) experienced in last month: Hip pain	0.3	0.4	2.5	0.1	-0.9	-0.6	1.0	-0.0	-1.6	-0.5	-0.3	-1.3	-0.3	-0.6	-0.8	-0.8	-0.9	-0.4	-0.0	-0.3	-0.7	-0.5	0.4	0.1	-0.3	-0.0	-0.1
Illnesses of father: High blood pressure	0.3	0.4	2.0	0.4	-0.3	0.0	-1.4	0.1	0.9	0.0	-0.5	1.1	1.3	0.7	0.5	0.3	0.5	0.7	-0.2	0.3	0.3	0.6	0.6	0.6	0.8	0.1	0.7
Number of operations (self-reported)	0.3	0.5	2.2	1.1	-0.9	-0.0	0.2	0.9	-1.5	0.2	-1.1	-0.3	0.3	0.7	0.1	0.5	-1.4	0.3	-0.3	-0.4	-0.3	0.2	1.2	-0.2	0.3	-0.6	0.3
Average weekly beer plus cider intake	0.3	0.4	2.9	0.6	-0.0	0.5	-1.1	0.4	1.5	-0.1	-0.4	1.0	0.5	0.1	1.1	0.4	1.7	0.6	0.3	-0.1	0.2	0.4	-0.1	0.4	0.3	0.3	0.2
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.6	-0.1	0.1	0.6	0.4	0.4	1.3	-0.6	-0.1	0.4	0.6	-0.2	0.4	-0.7	-0.7	-0.3	0.3	0.1	-0.4	0.5	-0.2	0.1	0.8	0.6	1.0
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	2.0	-1.2	0.0	-0.0	-0.3	-1.4	0.0	-0.3	1.3	0.9	0.8	-0.2	-0.8	-0.2	0.8	0.3	-0.2	0.1	-0.1	0.4	-0.2	-0.3	-0.1	-0.5	-0.9
Pain experienced in last month	0.3	0.5	2.1	-1.4	-0.1	-0.3	-1.1	-0.7	0.0	0.3	0.3	-1.2	-0.8	-0.5	-1.3	0.1	-1.2	-0.4	-0.2	-0.4	-0.5	0.3	-0.1	-1.1	-0.7	-0.9	-0.4
Heart attack/myocardial infarction (self-reported)	0.3	0.4	2.8	0.5	-0.4	-0.5	0.8	0.7	0.3	-0.8	-0.3	-0.0	-0.6	-0.3	0.2	-0.8	1.5	-0.4	0.2	-0.2	-0.4	-1.7	0.5	-0.2	-0.6	0.5	-0.6
Intelligence (Savage-Jansen 2018)	0.2	0.7	5.0	1.0	-0.6	0.5	-0.8	0.5	2.2	0.9	-0.5	0.9	1.3	0.8	-0.0	1.0	0.7	0.1	-0.3	-0.4	-0.3	0.2	0.6	-0.9	-0.3	-0.9	-1.1
Verbal and Numeric Reasoning (VNR)	0.2	0.5	3.6	0.7	-0.0	-0.4	-1.2	0.3	1.9	1.1	-0.2	0.9	-0.2	1.0	-0.4	1.0	1.2	-0.5	-0.2	0.4	-0.1	-0.1	0.7	-0.7	0.4	-0.2	-0.2
Tanning	0.2	2.9	6.2	1.3	2.0	1.8	-0.3	-1.4	0.7	2.5	1.5	1.3	1.6	2.3	1.7	2.2	0.9	2.1	2.0	1.8	1.8	1.6	2.2	1.9	1.7	2.0	1.7
Relative age of first facial hair	0.2	0.4	2.0	1.3	-0.5	1.4	-0.6	1.0	-0.1	0.1	-0.8	0.2	0.6	0.1	0.6	0.1	0.0	0.7	0.2	-0.4	-0.0	0.9	0.9	-0.8	-0.0	-0.8	0.4
Ever had hysterectomy (womb removed)	0.2	0.2	0.6	-0.2	0.3	-0.6	-0.1	-0.6	-0.7	0.8	0.5	-0.1	0.1	0.2	-0.1	0.5	-0.4	-0.1	0.4	0.6	-0.0	0.2	0.5	0.2	0.0	0.8	0.2
Medication for hormone replacement therapy	0.2	0.3	1.2	-0.9	-0.2	0.2	1.1	-0.4	-0.0	-0.6	0.4	-0.2	0.8	-0.7	0.2	-1.0	-0.6	0.6	0.2	0.1	-0.2	-0.1	0.1	0.6	-0.2	0.5	-0.5
Vitamin and mineral supplements	0.2	0.3	1.1	-0.6	-0.1	-0.8	-0.4	-0.6	0.6	0.3	0.5	-0.6	-0.1	-0.6	-0.5	-0.2	-0.4	-0.7	0.1	0.5	0.0	-0.8	-0.3	-0.1	-0.7	0.2	-1.1
Pack years adult smoking proportion	0.2	0.3	3.1	0.2	-0.1	-0.7	0.7	0.1	-1.8	-0.9	-0.2	-0.5	0.0	-0.4	-0.1	-0.6	-0.9	-0.1	0.0	-0.3	0.0	-0.4	-0.6	0.1	-0.1	0.0	0.4
Current tobacco smoking	0.2	0.3	2.7	-0.1	-0.5	-0.9	0.5	0.2	-0.7	-0.7	-0.2	0.0	-1.6	-0.2	-0.2	-0.5	0.5	-0.3	-0.2	-0.2	-0.3	-0.2	-0.3	-0.2	-0.4	-0.2	-0.7
Average weekly fortified wine intake	0.2	0.2	1.8	0.4	0.0	0.6	0.8	1.3	-0.1	-0.5	-1.0	0.2	-0.4	0.2	0.4	-0.3	-0.2	0.2	-0.1	-0.0	0.5	0.0	-0.2	0.2	0.3	-0.1	0.3
Serious illness, injury or assault to yourself	0.2	0.2	1.8	0.9	0.1	-0.0	1.3	0.7	0.2	-0.0	-0.4	0.2	-0.8	-0.2	-0.2	-0.1	-0.2	-0.5	-0.2	-0.2	0.1	0.9	-0.5	-0.2	-0.4	-0.2	-0.1
Body mass index (BMI)	0.2	0.7	4.0	0.1	-0.8	-0.8	1.3	0.4	-2.0	-0.7	-0.4	-1.1	-1.2	-0.1	-0.5	-0.3	-1.9	-0.4	-0.6	-0.7	-0.5	-0.1	-1.2	0.6	-0.4	-0.0	-0.5
Trunk fat mass	0.2	1.1	3.1	1.8	0.6	0.6	1.5	0.1	-1.0	0.9	0.1	0.5	-0.2	1.5	1.3	1.4	-0.8	1.3	0.6	0.7	1.2	0.9	0.1	1.8	1.1	1.2	0.9
Allergy	0.2	0.6	2.5	1.0	0.6	1.6	-1.2	0.3	0.0	0.2	0.0	0.3	1.0	0.7	1.1	0.3	0.6	1.1	0.6	0.6	1.1	0.9	0.4	0.3	0.6	-0.2	0.8
Diabetes (self-reported)	0.2	0.3	1.8	-0.5	0.4	0.1	-1.4	-0.9	-0.9	0.6	0.6	-0.2	0.3	0.4	-0.3	0.4	0.2	0.1	-0.1	0.1	-0.7	-0.4	0.3	-0.7	0.2	0.1	0.1
Fluid intelligence score	0.2	0.5	2.3	0.9	0.4	-0.0	-1.5	-0.1	0.8	1.2	0.3	0.8	-0.3	1.0	-0.1	1.1	1.2	-0.3	0.2	0.6	0.4	-0.2	0.8	-0.6	0.6	0.2	0.5
Falls in the last year	0.2	0.3	2.4	0.7	0.3	-0.1	0.6	-0.2	-0.3	-0.3	-0.2	0.7	0.6	0.4	0.7	0.7	-1.6	-0.1	-0.3	-0.8	-0.1	-0.1	-0.8	0.0	0.3	-0.1	0.6
Qualifications: A levels/AS levels or equivalent	0.2	0.5	2.3	0.5	0.8	0.8	0.2	-0.3	1.5	0.9	0.1	0.9	1.0	1.0	0.3	1.0	-0.2	-0.1	-0.1	0.2	0.0	0.1	0.8	-0.8	0.9	0.0	1.2
Prospective memory result	0.2	0.2	1.6	-0.0	0.0	-0.8	0.3	-0.4	-0.9	-0.3	-0.1	0.4	0.4	0.6	0.1	-0.2	1.3	0.5	-0.0	0.3	0.0	-0.1	0.2	0.6	0.1	-0.2	-0.6
Arm fat mass (right)	0.2	0.9	2.7	1.4	0.6	0.7	1.3	-0.2	-1.4	1.0	0.3	0.4	0.3	1.4	1.1	1.3	-0.9	1.2	0.6	0.7	1.0	1.1	0.2	1.6	1.0	1.0	0.7
Shortness of breath walking on level ground	0.2	0.3	0.7	-0.7	-0.7	-0.8	0.2	-0.0	-0.2	-0.6	-0.5	-0.8	-0.2	-0.5	-0.6	-0.8	-0.2	-0.5	-0.9	-0.0	-0.0	0.1	-0.5	-0.3	-0.4	-0.8	-0.2
Qualifications: College or University degree	0.2	0.6	6.0	0.7	-0.2	0.5	-2.4	0.9	1.2	1.0	-0.4	0.2	1.2	-0.1	-0.4	0.3	1.0	-0.0	-0.0	0.5	0.2	0.5	1.4	-0.7	-0.4	-0.1	-0.1
Mouth/teeth dental problems: Loose teeth	0.2	0.3	2.2	1.5	0.5	-0.0	0.6	0.4	-0.1	0.4	-0.2	0.8	0.2	0.7	0.5	1.0	0.4	0.3	-0.3	-0.0	0.3	0.1	-0.6	0.3	0.1	0.1	-0.5
Migraine (self-reported)	0.2	0.3	0.7	-0.8	0.6	0.7	0.8	-0.8	-0.4	-0.1	0.7	0.5	-0.1	0.0	0.0	-0.4	0.8	0.4	0.9	0.7	0.5	-0.2	0.6	-0.3	0.3	0.3	0.3
Leg fat mass (right)	0.2	0.6	3.2	1.4	-0.3	0.2	1.8	0.7	-1.3	-0.1	-0.6	-0.3	-0.6	0.7	0.9	0.4	-1.1	0.6	0.0	-0.1	0.5	0.6	-0.6	1.3	0.5	0.5	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	1.2	0.7	-0.1	0.2	-0.5	0.1	-0.4	0.7	-0.0	0.0	0.0	0.5	0.2	0.7	1.1	-0.0	-0.7	0.3	0.1	-0.5	-0.8	0.4	0.4	-0.4	0.7
Supplements: Vitamin C	0.2	0.3	2.9	0.4	-0.1	0.2	-1.0	0.8	-1.7	0.4	-0.4	-0.5	0.6	0.3	-0.2	0.1	-0.1	0.3	-0.2	0.1	-0.1	-0.5	-0.0	0.4	0.1	0.2	0.0
Knee pain experienced in last month	0.2	0.3	2.0	0.5	-0.0	-1.0	0.2	0.2	-0.6	-0.7	-0.1	-0.7	-0.6	-0.1	0.2	-0.5	-0.4	-0.5	0.0	0.2	0.5	-1.4	-0.8	0.8	-0.1	0.7	0.3
Diabetes diagnosed by doctor	0.2	0.4	2.0	-0.9	0.4	-0.5	-1.4	-1.1	-1.0	0.2	0.8	-0.7	-0.2	-0.0	-0.6	0.2	-0.5	-0.3	-0.1	-0.1	-0.7	-0.5	-0.2	-0.7	-0.1	-0.1	-0.3
Arm fat mass (left)	0.2	0.8	2.2	1.5	0.3	0.5	1.4	0.2	-1.5	0.8	0.1	0.2	-0.1	1.3	0.9	1.1	-1.1	1.0	0.5	0.5	0.7	0.9	0.1	1.5	0.8	0.9	0.5
Diastolic blood pressure, automated reading	0.2	0.6	2.9	-0.7	0.7	1.4	-0.8	-0.5	-1.0	-0.0	0.5	0.0	0.6	0.6	0.6	-0.2	-0.0	0.8	0.4	0.6	0.4	1.3	0.9	1.0	1.3	0.6	1.7
Pack years of smoking	0.2	0.3	3.5	0.5	0.1	-0.7	0.7	-0.1	-1.9	-0.6	0.1	-0.3	-0.1	-0.1	0.1	-0.4	-0.8	0.1	0.1	0.1	0.3	-0.1	-0.3	0.5	0.2	0.2	0.5
Leg fat mass (left)	0.2	0.6	2.5	1.6	-0.2	0.3	1.6	0.7	-1.1	0.1	-0.5	-0.1	-0.6	0.8	1.0	0.7	-1.0	0.7	0.2	-0.1	0.5	0.6	-0.5	1.5	0.5	0.7	0.5
Ovarian Cancer	0.1	0.2	0.6	-0.6	-0.3	0.2	0.5	-0.3	-0.8	-0.4	0.3	-0.4	-0.1	-0.6	-0.5	-0.5	-0.7	-0.1	-0.2	-0.3	-0.4	0.3	0.0	-0.4	-0.3	-0.2	0.2
HDL Cholesterol	0.1	0.2	0.7	-0.5	0.2	0.1	0.8	-0.8	-0.3	0.0	0.5	0.0	0.0	0.1	0.6	0.4	0.1	-0.4	0.2	-0.3	-0.5	0.1	-0.1	-0.8	0.0	-0.1	0.0
Heel T-Score	0.1	0.7	2.2	-1.4	-1.1	-1.2	-0.2	0.1	-0.5	-0.9	-0.0	-0.8	-1.4	-1.1	-1.5	-1.5	1.2	-0.3	-0.1	-0.3	-0.7	-0.7	-0.0	0.1	-1.0	0.1	-1.1
BMI	0.1	0.8	4.8	0.6	-0.7	0.4	1.4	1.2	-1.8	-0.9	-1.0	-0.4	-0.3	0.6	0.7	-0.2	-2.2	0.5	-0.1	-0.4	0.5	0.3	-0.9	1.4	0.6	0.6	1.1
Allergy or Eczema	0.1	0.3	1.6	0.0	-0.0	-0.1	0.6	0.8	0.2	-0.5	-0.7	0.2	-0.2	-0.7	-0.1	-0.4	-1.0	-0.3	-0.8	-0.8	-0.3	-0.4	-1.3	0.0	-0.5	-0.3	-0.4
Supplements: Zinc	0.1	0.1	0.5	0.6	0.4	0.1	0.5	0.1	0.5	0.1	0.1	0.3	0.2	0.5	0.2	0.7	-0.3	-0.1	0.2	0.0	0.4	-0.0	-0.2	0.1	0.4	0.3	0.3
Stomach or abdominal pain in last month	0.1	0.1	0.4	0.0	-0.6	0.4	-0.3	0.6	-0.0	-0.3	-0.3	-0.1	0.2	-0.2	0.0	-0.5	0.4	0.3	-0.3	0.2	-0.0	-0.1	0.4	0.5	0.1	0.1	0.4
Waist circumference	0.1	0.5	2.1	1.2	0.2	-0.0	0.9	0.1	-1.4	0.2	-0.1	-0.0	-0.4	0.9	0.4	0.5	-1.4	0.8	0.1	0.4	0.8	1.1	-0.5	1.4	0.6	0.6	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	1.0	0.5	-0.2	0.2	1.0	0.6	0.3	-0.7	-0.6	0.2	0.4	-0.4	1.0	-0.3	-0.2	0.2	0.0	-0.5	-0.0	0.1	-0.4	0.6	-0.3	0.3	-0.2
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.7	-0.8	0.4	0.2	-0.1	-0.4	0.1	0.1	0.1	-0.4	0.7	0.3	-0.4	-0.1	-0.5	0.2	0.2	0.2	0.1	-0.3	0.4	0.3	0.3	0.5	0.6
Pulse wave reflection index	0.1	0.1	0.4	0.6	0.5	0.4	0.4	0.2	-0.3	-0.3	0.2	0.2	0.1	-0.0	0.6	-0.0	-0.1	-0.3	0.5	-0.1	0.5	-0.5	-0.3	-0.3	0.3	0.7	0.7
Whole body fat mass	0.1	0.6	2.8	1.4	0.2	0.3	1.7	0.2	-1.2	0.5	-0.0	-0.0	-0.3	1.0	0.9	0.8	-1.0	0.8	0.3	0.3	0.7	0.6	-0.2	1.4	0.6	0.9	0.5
Smoking status: Current	0.1	0.1	1.3	0.2	-0.1	-0.6	0.3	0.1	-0.7	-0.3	-0.1	0.4	-1.1	0.2	0.3	-0.2	0.4	-0.0	0.2	0.3	0.3	0.1	0.1	0.2	0.1	0.3	-0.0
Medication: Blood pressure	0.1	0.2	1.6	-0.2	-0.1	-0.1	-0.4	-0.3	-0.9	-0.2	0.1	0.6	0.7	0.0	0.4	0.1	1.3	-0.5	-0.5	-0.2	-0.5	-0.1	-0.6	-0.7	0.5	-0.6	0.5
Hair Pigment	0.0	1.2	4.7	1.3	-1.1	-0.3	1.3	2.2	0.7	-1.1	-2.1	0.8	-1.4	-0.4	0.1	-0.3	-1.2	-0.9	-1.3	-1.6	-0.8	0.0	-0.9	-0.9	-0.5	-1.1	-0.1