TWAS
hub
About
Usage
Models
Genes
Traits
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Traits
:
Whole body fat-free mass
:
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→
chr3:40,537,829-42,251,329
Best TWAS P=9.43e-10 · Best GWAS P=1.9e-10 conditioned to 0.0455
40.6M
40.8M
41M
41.2M
41.4M
41.6M
41.8M
42M
42.2M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
NTR
Blood
CTNNB1
0.04
0.04
lasso
6
0.04
4.6e-13
6.0
-6.1
9.4e-10
-0.89
0.03
0.97
TRUE
1
GTEx
Artery Coronary
CTNNB1
0.30
0.00
lasso
4
0.01
1.0e-01
6.1
-5.9
2.8e-09
-0.93
0.03
0.44
FALSE
2
GTEx
Nerve Tibial
CTNNB1
0.05
0.00
enet
4
0.00
2.0e-01
5.5
5.7
1.5e-08
0.69
0.07
0.53
FALSE
4
The Cancer Genome Atlas
Liver Hepatocellular Carcinoma
ULK4
0.12
0.03
blup
256
0.05
1.9e-03
2.9
5.2
1.6e-07
0.33
0.22
0.13
FALSE