Best TWAS P=9.43e-10 · Best GWAS P=1.9e-10 conditioned to 0.0455
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | CTNNB1 | 0.30 | 0.00 | lasso | 4 | 0.01 | 1.0e-01 | 6.1 | -5.9 | 2.8e-09 | -0.93 | 0.03 | 0.44 | FALSE |
| 2 | GTEx | Nerve Tibial | CTNNB1 | 0.05 | 0.00 | enet | 4 | 0.00 | 2.0e-01 | 5.5 | 5.7 | 1.5e-08 | 0.69 | 0.07 | 0.53 | FALSE |
| 3 | NTR | Blood | CTNNB1 | 0.04 | 0.04 | lasso | 6 | 0.04 | 4.6e-13 | 6.0 | -6.1 | 9.4e-10 | -0.89 | 0.03 | 0.97 | TRUE |
| 4 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | ULK4 | 0.12 | 0.03 | blup | 256 | 0.05 | 1.9e-03 | 2.9 | 5.2 | 1.6e-07 | 0.33 | 0.22 | 0.13 | FALSE |