[Hub]/) : Traits : Whole body fat-free mass :

chr3:55,894,951-57,412,804

Best TWAS P=2.1e-15 · Best GWAS P=2.44e-13 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous FAM208A 0.12 0.09 enet 11 0.12 1.1e-09 -4.0 6.1 1.1e-09 -0.82 0.04 0.96 FALSE
2 GTEx Brain Hippocampus CCDC66 0.23 0.23 lasso 3 0.20 2.1e-05 -5.7 5.4 5.9e-08 -0.64 0.24 0.18 TRUE
3 GTEx Cells Transformed fibroblasts FAM208A 0.10 0.00 lasso 4 0.00 1.3e-01 -7.2 6.7 2.2e-11 -0.82 0.02 0.96 FALSE
4 GTEx Pituitary CCDC66 0.16 0.16 enet 31 0.12 6.8e-04 -3.3 5.7 1.0e-08 -0.68 0.03 0.90 FALSE
5 GTEx Skin Sun Exposed Lower leg FAM208A 0.06 0.04 lasso 2 0.03 2.0e-03 -5.5 5.5 5.0e-08 -0.65 0.17 0.56 TRUE
6 YFS Blood CCDC66 0.11 0.09 lasso 8 0.11 6.0e-34 -5.8 -5.9 3.6e-09 0.53 0.99 0.01 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma CCDC66 0.09 0.03 lasso 8 0.05 4.2e-11 -4.9 -6.9 6.9e-12 0.54 0.24 0.75 FALSE
8 The Cancer Genome Atlas Colon Adenocarcinoma CCDC66 0.14 0.12 lasso 2 0.10 1.2e-06 -5.2 -5.2 2.4e-07 0.47 0.57 0.23 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CCDC66 0.05 0.05 blup 56 0.06 1.0e-07 -7.1 -7.9 3.9e-15 0.79 0.00 1.00 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C3orf63 0.03 0.01 enet 4 0.01 1.3e-02 -7.1 6.5 6.6e-11 -0.89 0.01 0.88 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CCDC66 0.09 0.05 blup 56 0.06 5.3e-07 -5.8 -5.9 2.9e-09 0.69 0.69 0.31 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma CCDC66 0.16 0.13 enet 12 0.16 3.1e-17 -5.8 -5.6 2.2e-08 0.34 0.96 0.04 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma CCDC66 0.05 0.06 blup 56 0.05 9.7e-07 -7.1 -7.9 2.1e-15 0.73 0.00 1.00 TRUE
14 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CCDC66 0.03 0.03 blup 56 0.03 9.6e-05 -5.2 -6.4 1.3e-10 0.51 0.35 0.24 FALSE
15 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CCDC66 0.08 0.01 blup 56 0.07 7.2e-04 -5.8 -5.7 1.2e-08 0.32 0.12 0.07 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma CCDC66 0.15 0.10 enet 11 0.13 7.3e-14 -5.2 -5.9 3.8e-09 0.48 0.97 0.03 TRUE
17 The Cancer Genome Atlas Stomach Adenocarcinoma CCDC66 0.05 0.01 blup 57 0.02 8.4e-03 -4.9 -6.5 7.2e-11 0.55 0.08 0.51 FALSE