[Hub]/) : Traits : Whole body fat-free mass : ← →

chr3:55,894,951-57,412,804

Best TWAS P=2.1e-15 · Best GWAS P=2.44e-13 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	FAM208A	0.12	0.09	enet	11	0.12	1.1e-09	-4.0	6.1	1.1e-09	-0.82	0.04	0.96	FALSE
2	GTEx	Brain Hippocampus	CCDC66	0.23	0.23	lasso	3	0.20	2.1e-05	-5.7	5.4	5.9e-08	-0.64	0.24	0.18	TRUE
3	GTEx	Cells Transformed fibroblasts	FAM208A	0.10	0.00	lasso	4	0.00	1.3e-01	-7.2	6.7	2.2e-11	-0.82	0.02	0.96	FALSE
4	GTEx	Pituitary	CCDC66	0.16	0.16	enet	31	0.12	6.8e-04	-3.3	5.7	1.0e-08	-0.68	0.03	0.90	FALSE
5	GTEx	Skin Sun Exposed Lower leg	FAM208A	0.06	0.04	lasso	2	0.03	2.0e-03	-5.5	5.5	5.0e-08	-0.65	0.17	0.56	TRUE
6	YFS	Blood	CCDC66	0.11	0.09	lasso	8	0.11	6.0e-34	-5.8	-5.9	3.6e-09	0.53	0.99	0.01	FALSE
7	The Cancer Genome Atlas	Breast Invasive Carcinoma	CCDC66	0.09	0.03	lasso	8	0.05	4.2e-11	-4.9	-6.9	6.9e-12	0.54	0.24	0.75	FALSE
8	The Cancer Genome Atlas	Colon Adenocarcinoma	CCDC66	0.14	0.12	lasso	2	0.10	1.2e-06	-5.2	-5.2	2.4e-07	0.47	0.57	0.23	FALSE
9	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CCDC66	0.05	0.05	blup	56	0.06	1.0e-07	-7.1	-7.9	3.9e-15	0.79	0.00	1.00	FALSE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C3orf63	0.03	0.01	enet	4	0.01	1.3e-02	-7.1	6.5	6.6e-11	-0.89	0.01	0.88	FALSE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CCDC66	0.09	0.05	blup	56	0.06	5.3e-07	-5.8	-5.9	2.9e-09	0.69	0.69	0.31	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	CCDC66	0.16	0.13	enet	12	0.16	3.1e-17	-5.8	-5.6	2.2e-08	0.34	0.96	0.04	FALSE
13	The Cancer Genome Atlas	Lung Adenocarcinoma	CCDC66	0.05	0.06	blup	56	0.05	9.7e-07	-7.1	-7.9	2.1e-15	0.73	0.00	1.00	TRUE
14	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CCDC66	0.03	0.03	blup	56	0.03	9.6e-05	-5.2	-6.4	1.3e-10	0.51	0.35	0.24	FALSE
15	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CCDC66	0.08	0.01	blup	56	0.07	7.2e-04	-5.8	-5.7	1.2e-08	0.32	0.12	0.07	FALSE
16	The Cancer Genome Atlas	Prostate Adenocarcinoma	CCDC66	0.15	0.10	enet	11	0.13	7.3e-14	-5.2	-5.9	3.8e-09	0.48	0.97	0.03	TRUE
17	The Cancer Genome Atlas	Stomach Adenocarcinoma	CCDC66	0.05	0.01	blup	57	0.02	8.4e-03	-4.9	-6.5	7.2e-11	0.55	0.08	0.51	FALSE