Hub : Genes

C3orf63

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 NTR Blood 0.0178 0.0066 5.7e-05 0.011 0.013 0.017 0.013 0.014 9.5e-05 2.9e-05 2.0e-06 2.4e-05 1.9e-05
2 TCGA Kidney Renal Clear Cell Carcinoma 0.0252 0.0164 9.7e-03 0.014 0.010 0.013 NA 0.012 9.4e-03 2.2e-02 1.3e-02 NA 1.4e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.3 0.4 0.4 -0.7 0.6
Bipolar Disorder or Schizophrenia 0.4 1.0 1.9 -1.4 0.4
Depressed Affect (Nagel 2018) 1.1 2.3 3.6 1.0 -1.9
Depression (Nagel 2018) 0.4 0.6 1.2 1.1 -0.3
Intelligence (Savage-Jansen 2018) 2.5 7.5 13.2 -1.4 3.6
Neuroticism (Nagel 2018) 2.2 5.1 5.3 2.3 -2.2
Schizophrenia (2018) 0.3 0.7 1.4 -1.2 -0.0
Schizophrenia vs Biploar Disorder 1.1 1.4 2.8 0.2 -1.7
Worry (Nagel 2018) 1.1 2.4 3.2 1.3 -1.8
Alzheimer’s Disease (in mother) 0.6 0.8 1.4 1.2 0.3
Alzheimer’s Disease (in father) 0.1 0.1 0.1 0.1 0.3
Alzheimer’s Disease (including proxy) 0.8 1.2 1.9 1.4 -0.6
Crohns Disease (2017) 3.6 7.9 12.7 -1.7 3.6
Irritable Bowel Disease (IBD) 0.1 0.2 0.4 -0.0 0.7
Ulcerative Colitis (UC) 1.7 3.2 4.6 1.4 -2.2
Major Depression (MDD) 0.0 0.1 0.1 0.3 0.1
Reaction Time 2.2 4.2 7.0 1.2 -2.6
Verbal and Numeric Reasoning (VNR) 1.9 4.6 9.1 0.2 3.0
Breast Cancer 0.8 1.9 3.7 1.9 0.2
Ovarian Cancer 0.6 0.8 1.0 1.0 -0.8
Prostate Cancer 0.5 0.7 1.3 0.3 -1.1
Age at First Birth 0.6 0.9 1.5 -1.2 0.5
Bipolar Disorder (2011) 0.8 0.7 1.1 -1.0 0.7
Body Mass Index (BMI) (2010) 1.1 1.5 1.8 -1.1 1.3
Coronary Artery Disease (CAD) 0.1 0.1 0.2 -0.5 -0.1
Crohns Disease (2012) 4.5 7.2 11.5 -1.7 3.4
Mean Putamen Volume 0.5 0.6 0.9 -0.5 0.9
Fasting Glucose 1.1 1.4 1.9 -0.9 1.4
HbA1C 0.5 0.5 0.7 0.9 0.6
HDL Cholesterol 2.4 4.0 4.9 1.7 -2.2
LDL Cholesterol 0.1 0.2 0.3 0.5 -0.3
Lupus 0.0 0.0 0.0 -0.0 0.0
Neuroticism (2016) 1.6 2.3 2.7 1.6 -1.4
Primary Biliary Cirrhosis 0.1 0.1 0.2 0.4 -0.1
Rheumatoid Arthritis 0.6 0.8 1.5 -1.2 -0.3
Schizophrenia (2014) 0.7 1.6 3.0 -1.7 -0.5
Triglycerides 5.0 8.2 12.0 -3.5 2.1
Type 2 Diabetes (T2D) (2012) 0.5 0.5 1.0 -0.2 1.0
Ulcerative Colitis 2.6 3.8 6.5 1.1 -2.6
Blood Eosinophil Count 0.8 6.0 12.1 0.1 3.5
Blood Platelet Count 16.9 196.4 234.1 15.3 -12.6
Blood Red Count 8.5 82.3 112.4 -7.2 10.6
Blood White Count 0.3 2.4 3.2 -1.3 1.8
Heel T-Score 5.5 43.6 67.7 4.4 -8.2
BMI 0.2 0.9 1.1 -1.1 -0.8
Height 4.2 81.7 161.3 -1.5 12.7
Waist Hip Ratio (WHR) 0.5 2.1 2.7 1.6 -1.2
Systolic Blood Pressure 3.4 17.0 23.3 -3.3 4.8
Smoking Status 1.6 3.7 4.9 1.6 -2.2
Allergy or Eczema 4.6 12.0 22.4 -1.3 4.7
Cardiovascular Disease 3.0 9.8 10.4 -3.0 3.2
Hypothyroidism (self reported) 0.3 0.8 1.3 1.1 0.5
Respiratory disease 6.6 14.7 23.2 -2.5 4.8
Type 2 Diabetes (T2D) (2018) 0.0 0.1 0.1 0.3 -0.2
Lung FEV1/FVC ratio 1.4 6.9 11.1 -3.3 1.6
Lung FVC 0.5 2.3 4.6 0.2 -2.2
Neuroticism 1.9 4.6 6.2 1.7 -2.5
Chronotype (morning person) 1.7 3.9 6.4 -1.2 2.5
Hair Pigment 0.0 1.3 1.6 -1.3 -1.0
Tanning 0.1 0.7 1.2 1.1 -0.3
Hand grip strength (left) 0.4 1.0 1.6 0.5 -1.3
Number of treatments/medications taken 1.4 2.6 3.0 -1.7 1.5
Average weekly spirits intake 0.0 0.1 0.1 -0.1 0.3
Sensitivity / hurt feelings 3.5 5.9 6.1 2.4 -2.5
Frequency of depressed mood in last 2 weeks 1.5 2.1 3.5 1.9 -0.8
Hearing difficulty/problems: Yes 0.6 1.0 1.3 1.1 -0.8
Relative age of first facial hair 0.5 0.9 1.3 -0.8 1.1
Other serious medical condition/disability diagnosed by doctor 0.7 0.8 1.2 -0.7 1.1
Ever used hormone-replacement therapy (HRT) 3.0 3.8 6.7 -0.9 -2.6
Ever had hysterectomy (womb removed) 2.1 2.3 4.4 2.1 -0.5
Systolic blood pressure, automated reading 1.7 5.0 5.2 -2.3 2.2
Eye problems/disorders: Diabetes related eye disease 0.5 0.6 1.1 -1.1 0.0
Angina 2.0 2.6 3.1 -1.8 1.5
Medication for hormone replacement therapy 1.1 1.3 1.8 0.8 -1.4
Vitamin and mineral supplements 2.4 3.2 5.5 2.3 -1.0
Supplements: Zinc 0.8 0.8 1.2 -1.1 0.7
Medication: Co-codamol 0.6 0.7 1.3 1.1 0.2
Medication: Metformin 0.3 0.4 0.7 -0.8 0.3
Diabetes (father) 1.0 1.3 2.1 -1.4 0.7
Diabetes (mother) 0.1 0.1 0.2 0.5 0.1
Severe depression (siblings) 0.2 0.2 0.4 -0.6 -0.0
Pack years adult smoking proportion 0.1 0.1 0.2 0.4 0.1
Impedance of leg (right) 0.2 0.7 0.9 0.7 -1.0
Leg fat-free mass (left) 3.5 18.6 31.5 -2.4 5.6
Trunk fat percentage 0.4 1.7 3.3 -1.8 0.2
Hand grip strength (right) 0.0 0.1 0.1 0.3 -0.1
Townsend deprivation index at recruitment 0.5 0.7 1.2 -1.1 0.4
Current tobacco smoking 1.3 2.2 3.0 1.7 -1.1
Average weekly fortified wine intake 0.7 0.8 1.6 1.3 0.2
Maternal smoking around birth 0.7 1.0 1.4 0.8 -1.2
Fed-up feelings 0.4 0.7 1.3 0.3 -1.1
Frequency of unenthusiasm / disinterest in last 2 weeks 1.7 2.3 4.1 2.0 -0.7
Relative age voice broke 0.2 0.4 0.6 -0.3 0.8
Taking other prescription medications 0.4 0.5 0.7 -0.6 0.9
Age when periods started (menarche) 0.5 1.2 2.1 -1.5 -0.5
Bilateral oophorectomy (both ovaries removed) 1.4 1.6 2.8 1.7 0.7
Heel bone mineral density (BMD) T-score, automated (left) 2.9 6.6 8.8 2.1 -3.0
Tinnitus: Yes, but not now, but have in the past 5.4 5.7 6.3 2.5 -2.3
Qualifications: CSEs or equivalent 1.2 1.6 3.2 -0.2 -1.8
Serious illness, injury or assault to yourself 0.9 1.1 1.9 -0.6 1.4
High blood pressure 4.8 13.5 16.2 -4.0 3.3
Hayfever, allergic rhinitis or eczema 5.1 11.1 21.8 -0.7 4.7
Multivitamins +/- minerals 8.4 10.6 14.4 -3.8 2.6
Stomach or abdominal pain in last month 0.4 0.6 1.0 0.2 1.0
Supplements: Glucosamine 0.6 0.8 1.1 -0.7 1.1
Diverticular disease/diverticulitis (self-reported) 1.3 1.6 2.8 1.7 -0.6
Medication: Atenolol 0.0 0.0 0.0 -0.1 -0.1
Medication: Levothyroxine sodium 0.8 1.3 2.5 1.6 -0.4
Sitting height 2.6 18.3 36.0 0.8 6.0
Chronic bronchitis/emphysema (father) 1.1 1.3 2.4 -0.3 1.6
High blood pressure (mother) 3.5 4.8 8.5 -1.1 2.9
Body mass index (BMI) 0.2 0.9 1.7 -1.3 -0.2
Impedance of leg (left) 0.3 1.3 1.9 0.8 -1.4
Leg predicted mass (left) 3.5 18.8 31.7 -2.4 5.6
Trunk fat mass 1.1 4.8 5.3 -2.3 2.1
Waist circumference 1.4 5.1 6.9 -2.6 1.8
Number of incorrect matches in round 0.9 1.5 2.1 -0.9 -1.4
Past tobacco smoking 0.7 1.4 2.3 -1.5 0.6
Alcohol usually taken with meals 0.6 1.0 1.1 1.0 -1.0
Nervous feelings 2.8 5.2 5.9 2.1 -2.4
Frequency of tenseness / restlessness in last 2 weeks 2.6 4.0 4.6 2.1 -1.8
Hearing difficulty/problems with background noise 0.9 1.4 1.5 1.1 -1.2
Hair/balding pattern: Pattern 2 0.1 0.1 0.2 0.2 0.4
Had menopause 1.5 1.8 1.8 -1.4 -1.4
Had other major operations 0.5 0.6 0.9 -0.5 1.0
Forced vital capacity (FVC) 0.9 3.4 6.7 0.2 2.6
Heel bone mineral density (BMD) T-score, automated (right) 3.3 7.5 8.3 2.6 -2.9
Ever unenthusiastic/disinterested for a whole week 5.1 6.2 7.1 2.7 -2.3
Qualifications: None of the above 5.4 11.6 20.3 1.7 -4.5
Financial difficulties in last 2 years 0.7 1.0 1.3 1.2 -0.8
Mouth/teeth dental problems 1.6 2.5 4.1 -1.0 2.0
Heart attack 0.4 0.5 0.7 -0.8 0.5
Allergy 6.4 14.8 27.9 1.3 -5.3
Pain all over the body in last month 0.3 0.3 0.6 0.2 -0.8
Diabetes (self-reported) 0.3 0.4 0.8 -0.3 -0.9
Hayfever/allergic rhinitis (self-reported) 0.4 0.5 0.9 0.4 0.9
Medication: Ramipril 1.2 1.5 2.3 -0.8 1.5
Medication: Simvastatin 0.0 0.0 0.0 0.2 -0.0
Fluid intelligence score 1.9 4.0 7.8 0.3 2.8
Illnesses of siblings 0.7 1.0 2.0 0.0 -1.4
Neuroticism score 0.8 1.6 2.2 1.0 -1.5
Weight 2.4 11.6 19.0 -2.1 4.4
Impedance of arm (right) 0.1 0.3 0.6 -0.8 0.1
Arm fat percentage (right) 0.6 2.2 4.4 -2.1 -0.1
Trunk fat-free mass 4.8 27.3 50.6 -2.0 7.1
Hip circumference 2.0 8.5 11.2 -2.4 3.4
Time employed in main current job 2.9 3.4 3.4 1.8 -1.8
Alcohol intake versus 10 years previously 0.5 0.8 1.2 -1.1 0.7
Father’s age at death 4.1 5.5 6.0 2.4 -2.2
Worrier / anxious feelings 0.2 0.4 0.7 0.4 -0.9
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.9 1.7 0.1 -1.3
Falls in the last year 3.2 4.4 7.0 -2.6 1.3
Hair/balding pattern: Pattern 3 1.2 1.8 2.8 -0.9 -1.7
Number of live births 0.2 0.3 0.4 0.6 0.5
Forced expiratory volume in 1-second (FEV1) 1.0 3.4 6.5 -0.5 2.5
Pulse rate 2.1 3.6 4.3 1.7 -2.1
Happiness 0.7 0.8 0.9 0.8 0.9
Noisy workplace 1.4 1.8 1.9 1.3 -1.4
Qualifications: A levels/AS levels or equivalent 1.6 3.6 7.2 -0.2 2.7
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.2 0.4 0.6 -0.0
Mouth/teeth dental problems: Dentures 0.1 0.2 0.4 0.2 -0.6
Asthma 6.0 11.9 18.1 -2.4 4.3
Medication: Ibuprofen (e.g. Nurofen) 0.1 0.1 0.2 -0.1 -0.4
Medication: Cholesterol lowering 0.2 0.3 0.5 0.4 0.7
Depression (self-reported) 2.4 2.8 4.2 1.2 -2.1
Medication: Lansoprazole 0.7 0.8 1.5 -0.3 -1.2
Prospective memory result 2.0 2.4 4.7 -0.3 -2.2
Lung cancer (father) 1.2 1.5 1.7 -1.1 1.3
Illnesses of mother 2.2 2.7 4.2 1.1 -2.0
Forced expiratory volume in 1-second (FEV1), Best measure 1.8 5.6 9.6 -1.3 3.1
Pulse wave Arterial Stiffness index 1.7 2.0 3.6 -1.9 0.6
Impedance of arm (left) 0.1 0.2 0.5 -0.1 -0.7
Arm fat mass (right) 1.0 4.0 5.0 -2.2 1.8
Trunk predicted mass 4.7 27.0 50.1 -2.0 7.1
Standing height 5.6 55.3 106.1 -2.1 10.3
Length of working week for main job 1.4 1.6 2.9 1.7 -0.5
Exposure to tobacco smoke at home 2.2 2.5 3.1 -1.4 1.8
Breastfed as a baby 1.2 1.5 1.6 1.3 -1.2
Tense / ‘highly strung’ 1.6 2.6 3.7 1.9 -1.3
Seen doctor (GP) for nerves, anxiety, tension or depression 2.4 3.6 3.9 1.8 -2.0
Hair/balding pattern: Pattern 4 0.5 1.1 1.7 0.8 -1.3
Birth weight of first child 3.6 6.4 11.4 -1.2 3.4
Peak expiratory flow (PEF) 0.4 1.0 1.8 -0.5 1.3
Pulse wave reflection index 1.1 1.3 2.5 -1.6 0.4
Ever highly irritable/argumentative for 2 days 2.2 2.7 3.5 1.4 -1.9
Loud music exposure frequency 0.6 0.7 0.7 0.8 -0.9
Qualifications: O levels/GCSEs or equivalent 3.1 5.0 6.5 -1.9 2.5
Mouth/teeth dental problems: Bleeding gums 4.6 6.0 6.2 2.4 -2.5
Blood clot in the leg (DVT) 0.6 0.7 1.4 0.3 -1.2
Medication: Paracetamol 1.5 2.5 4.8 0.5 -2.2
Headache pain in last month 0.3 0.4 0.5 0.7 0.6
Medication for cholesterol, blood pressure or diabetes 2.1 3.4 4.4 1.6 -2.1
Glaucoma (self-reported) 4.4 5.2 6.6 -2.0 2.6
Gout (self-reported) 1.1 1.5 2.9 1.7 0.1
Hypothyroidism/myxoedema (self-reported) 0.4 0.8 1.6 1.3 0.1
Medication: Amlodipine 4.5 6.3 6.4 -2.5 2.5
Medication: Ventolin 100micrograms inhaler 2.7 3.5 4.9 -2.2 1.4
Birth weight 2.0 4.4 7.6 -1.1 2.8
Chronic bronchitis/emphysema (mother) 2.8 3.2 3.4 1.8 -1.8
High blood pressure (siblings) 1.5 2.1 4.2 -0.2 2.1
Forced vital capacity (FVC), Best measure 1.3 4.9 9.3 -0.7 3.0
Body fat percentage 0.3 1.4 2.5 -1.6 -0.4
Leg fat percentage (right) 0.3 1.2 1.8 -0.8 -1.3
Arm fat-free mass (right) 3.1 15.7 29.8 -1.3 5.5
Exposure to tobacco smoke outside home 0.9 1.2 2.3 -1.5 0.4
Comparative body size at age 10 1.1 3.2 5.1 1.1 -2.2
Number of full brothers 2.8 3.6 4.2 -1.7 2.1
Worry too long after embarrassment 1.9 3.2 3.5 1.7 -1.9
Seen a psychiatrist for nerves, anxiety, tension or depression 0.6 0.8 1.5 1.2 -0.4
Wheeze or whistling in the chest in last year 3.5 6.3 7.3 -2.3 2.7
Number of children fathered 6.7 7.6 9.8 3.1 -2.3
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.5 0.6 0.6 0.8
Age at first live birth 0.4 0.8 1.6 -0.0 1.2
Pulse wave peak to peak time 1.0 1.1 2.3 1.5 0.2
Health satisfaction 2.1 2.7 3.0 -1.5 1.7
Shortness of breath walking on level ground 0.2 0.2 0.2 0.5 -0.4
Qualifications: College or University degree 2.4 7.6 13.4 -1.3 3.7
Eye problems/disorders: None of the above 0.3 0.3 0.6 0.8 -0.3
Mouth/teeth dental problems: Loose teeth 4.1 4.9 5.0 2.2 -2.2
Emphysema/chronic bronchitis 0.5 0.5 1.0 0.2 1.0
Medication for pain relief, constipation, heartburn 0.7 1.2 2.3 0.5 1.5
Neck or shoulder pain in last month 0.4 0.6 0.8 0.6 -0.9
Medication: Blood pressure 3.9 6.9 7.1 -2.6 2.7
Angina (self-reported) 2.0 2.6 2.8 -1.7 1.6
Migraine (self-reported) 0.1 0.1 0.2 -0.5 -0.0
Medication: Ibuprofen 0.1 0.1 0.1 -0.2 -0.4
Medication: Allopurinol 0.6 0.8 1.5 1.2 0.2
Medication: Omeprazole 2.3 2.8 5.2 0.6 -2.3
Medication: Seretide 50 evohaler 0.2 0.2 0.4 0.7 0.1
Mean time to correctly identify matches 2.0 3.7 7.5 0.2 -2.7
Heart disease (mother) 3.0 3.7 5.5 -2.3 1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 5.4 6.5 9.3 1.9 -3.0
Whole body fat mass 1.0 4.3 5.4 -2.3 1.8
Leg fat mass (right) 0.6 2.5 3.6 -1.9 1.1
Arm predicted mass (right) 3.0 15.5 28.9 -1.4 5.4
Pulse rate, automated reading 4.2 13.6 16.1 4.0 -3.3
Alcohol intake frequency. 2.4 5.6 6.3 -2.5 2.2
Comparative height size at age 10 1.8 10.0 19.8 -0.5 4.5
Number of full sisters 0.3 0.3 0.5 -0.4 -0.7
Suffer from ‘nerves’ 1.4 2.2 3.8 0.7 -1.9
Overall health rating 2.5 5.3 7.0 -2.6 1.9
Chest pain or discomfort 0.2 0.3 0.4 -0.5 0.6
Had major operations 0.0 0.0 0.1 -0.3 0.2
Age at last live birth 0.9 1.2 1.4 1.0 1.2
Family relationship satisfaction 0.1 0.2 0.3 0.1 0.6
Leg pain on walking 0.3 0.4 0.9 0.9 0.1
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.3 0.5 -0.7 -0.4
Commuting to job workplace: Car/motor vehicle 0.1 0.2 0.3 -0.5 -0.2
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 0.9 -1.0 -0.4
Medication: Aspirin 0.1 0.1 0.2 -0.4 0.1
Supplements: Vitamin C 0.5 0.6 0.9 -1.0 -0.6
Knee pain experienced in last month 0.8 1.3 1.9 -0.9 1.4
Hypertension (Self-reported) 6.2 17.2 21.9 -4.7 3.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.2 1.4 2.7 0.2 -1.6
Illnesses of father: Heart disease 1.5 2.1 4.2 2.0 -0.0
Illnesses of siblings: Diabetes 0.4 0.5 0.8 0.9 0.4
Smoking status: Previous 0.1 0.1 0.2 0.5 -0.3
Forced expiratory volume in 1-second (FEV1), predicted 2.6 5.3 9.4 -1.1 3.1
Whole body fat-free mass 4.2 23.7 42.6 -2.2 6.5
Leg fat-free mass (right) 3.2 17.2 29.9 -2.1 5.5
Arm fat percentage (left) 0.4 1.6 2.8 -1.7 -0.6
Average weekly red wine intake 0.1 0.1 0.3 -0.5 0.2
Handedness (chirality/laterality): Left-handed 4.0 4.8 6.7 -2.6 1.7
Mood swings 1.3 2.4 4.8 -0.2 -2.2
Loneliness, isolation 0.7 0.9 1.4 1.2 -0.7
Long-standing illness, disability or infirmity 3.5 5.3 6.6 -2.0 2.6
Ever had bowel cancer screening 1.2 1.4 1.9 -1.0 -1.4
Diabetes diagnosed by doctor 0.0 0.0 0.0 -0.2 -0.2
Ever had stillbirth, spontaneous miscarriage or termination 0.1 0.1 0.2 -0.0 0.4
Friendships satisfaction 0.1 0.2 0.3 0.5 -0.0
Qualifications: nursing, teaching 2.2 3.4 5.2 -1.3 2.3
Commuting to job workplace: Walk 1.3 1.4 1.5 1.2 -1.1
Eye problems/disorders: Cataract 0.4 0.5 0.8 -0.9 -0.3
Mouth/teeth dental problems: Mouth ulcers 0.2 0.3 0.4 0.3 -0.6
Medication for cholesterol 0.8 1.3 1.8 1.4 -0.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.9 1.1 1.7 0.7 -1.3
Back pain experienced in last month 0.1 0.2 0.3 0.2 -0.5
Mineral and other dietary supplements 5.8 7.8 11.2 3.4 -2.1
Breast cancer (self-reported) 0.3 0.4 0.6 0.5 -0.8
Asthma (self-reported) 5.9 11.8 18.1 -2.3 4.3
Osteoporosis (self-reported) 0.1 0.1 0.2 -0.1 0.5
Osteoarthritis (self-reported) 3.2 4.2 7.2 -2.7 1.1
Medication: Aspirin 0.0 0.1 0.1 -0.3 0.2
Medication: Gliclazide 0.4 0.4 0.5 -0.7 0.6
Illnesses of father: None of the above (group 1) 1.3 1.6 3.1 -0.0 -1.8
Smoking status: Current 1.4 2.1 3.3 1.8 -1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.5 1.0 2.0 -1.4 0.1
Whole body water mass 3.9 22.3 40.5 -2.0 6.4
Leg predicted mass (right) 3.2 16.9 29.3 -2.1 5.4
Arm fat mass (left) 0.7 2.9 3.5 -1.9 1.5
Number of self-reported non-cancer illnesses 1.0 1.8 2.9 -0.8 1.7
Average weekly champagne plus white wine intake 1.7 2.3 3.6 1.9 1.0
Miserableness 1.5 2.7 3.0 1.7 -1.5
Guilty feelings 2.7 4.0 4.9 1.8 -2.2
Wears glasses or contact lenses 0.3 0.4 0.7 0.1 0.9
Ever taken oral contraceptive pill 0.5 0.6 0.7 0.7 0.8
Hearing aid user 2.4 2.7 3.4 1.9 -1.4
Mother’s age at death 0.0 0.0 0.0 -0.2 -0.1
Financial situation satisfaction 0.9 1.1 1.6 1.3 -0.8
Tinnitus: Yes, now most or all of the time 0.3 0.4 0.8 0.1 -0.9
Commuting to job workplace: Public transport 0.9 1.0 1.8 0.5 1.3
Eye problems/disorders: Glaucoma 3.1 3.7 4.5 -1.7 2.1
Medication: Blood pressure 4.9 9.4 9.6 -3.0 3.1
Pain type(s) experienced in last month: Hip pain 0.1 0.1 0.1 -0.4 -0.0
Supplements: Fish oil (including cod liver oil) 4.5 5.8 8.1 -2.9 1.9
High cholesterol (Self-reported) 0.5 0.8 0.8 0.9 -0.9
Medication: Bendroflumethiazide 1.9 2.9 3.2 -1.8 1.6
Medication: Paracetamol 0.8 1.2 2.5 -0.1 -1.6
Medication: Lisinopril 1.9 2.4 3.6 -1.1 1.9
Medication: Atorvastatin 1.1 1.4 2.2 -0.7 1.5
Illnesses of father: High blood pressure 1.1 1.4 2.3 1.5 0.6
Alcohol drinker status: Never 3.7 4.4 6.2 -2.5 1.6
Ever smoked 3.4 5.9 8.5 2.9 -1.8
Basal metabolic rate 3.9 21.5 38.1 -2.2 6.2
Leg fat percentage (left) 0.4 1.5 2.0 -1.0 -1.4
Arm fat-free mass (left) 3.7 18.8 33.8 -1.9 5.8
Number of operations (self-reported) 1.3 2.0 3.4 0.7 1.8
Average weekly beer plus cider intake 0.6 0.8 1.1 -0.7 -1.0
Irritability 0.4 0.7 1.4 0.0 1.2
Risk taking 0.2 0.3 0.5 -0.7 -0.3
Ever had prostate specific antigen (PSA) test 0.8 0.9 1.0 -0.9 1.0
Fractured/broken bones in last 5 years 0.7 0.9 1.7 0.4 -1.3
Age started oral contraceptive pill 0.3 0.4 0.5 -0.5 -0.7
Diastolic blood pressure, automated reading 2.3 7.2 9.2 -2.3 3.0
Ever depressed for a whole week 0.4 0.4 0.6 -0.5 -0.8
Unable to work because of sickness or disability 0.5 0.6 0.8 -0.6 0.9
Commuting to job workplace: Cycle 0.5 0.6 1.1 -1.1 0.3
Myopia 2.2 3.2 3.5 -1.7 1.9
Vascular/heart problems diagnosed by doctor 4.3 11.7 14.7 3.8 -3.0
Cholesterol lowering medication 0.4 0.6 1.1 -0.3 -1.1
Medication: Omeprazole (e.g. Zanprol) 3.2 3.9 6.8 1.0 -2.6
Pain experienced in last month 0.9 1.5 2.1 1.5 -0.9
Supplements: Calcium 0.1 0.2 0.3 0.1 -0.6
Basal cell carcinoma (self-reported) 0.6 0.7 1.2 -1.1 0.5
Heart attack/myocardial infarction (self-reported) 0.5 0.7 0.9 -0.9 0.7
Deep venous thrombosis (DVT) (self-reported) 0.6 0.8 1.4 0.4 -1.2
Heart disease (siblings) 0.1 0.1 0.1 -0.4 -0.3
Alcohol drinker status: Previous 0.2 0.2 0.2 0.4 -0.5
Pack years of smoking 0.1 0.1 0.3 -0.2 0.5
Impedance of whole body 0.1 0.3 0.5 0.3 -0.7
Leg fat mass (left) 0.7 2.8 4.0 -2.0 1.2
Arm predicted mass (left) 3.5 17.7 32.3 -1.8 5.7