TWAS hub - C3orf63

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	NTR	Blood	0.0178	0.0066	5.7e-05	0.011	0.013	0.017	0.013	0.014	9.5e-05	2.9e-05	2.0e-06	2.4e-05	1.9e-05
2	TCGA	Kidney Renal Clear Cell Carcinoma	0.0252	0.0164	9.7e-03	0.014	0.010	0.013	NA	0.012	9.4e-03	2.2e-02	1.3e-02	NA	1.4e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Blood Platelet Count	16.9	196.4	234.1	15.3	-12.6
Blood Red Count	8.5	82.3	112.4	-7.2	10.6
Multivitamins +/- minerals	8.4	10.6	14.4	-3.8	2.6
Number of children fathered	6.7	7.6	9.8	3.1	-2.3
Respiratory disease	6.6	14.7	23.2	-2.5	4.8
Allergy	6.4	14.8	27.9	1.3	-5.3
Hypertension (Self-reported)	6.2	17.2	21.9	-4.7	3.5
Asthma	6.0	11.9	18.1	-2.4	4.3
Asthma (self-reported)	5.9	11.8	18.1	-2.3	4.3
Mineral and other dietary supplements	5.8	7.8	11.2	3.4	-2.1
Standing height	5.6	55.3	106.1	-2.1	10.3
Heel T-Score	5.5	43.6	67.7	4.4	-8.2
Tinnitus: Yes, but not now, but have in the past	5.4	5.7	6.3	2.5	-2.3
Qualifications: None of the above	5.4	11.6	20.3	1.7	-4.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	5.4	6.5	9.3	1.9	-3.0
Hayfever, allergic rhinitis or eczema	5.1	11.1	21.8	-0.7	4.7
Ever unenthusiastic/disinterested for a whole week	5.1	6.2	7.1	2.7	-2.3
Triglycerides	5.0	8.2	12.0	-3.5	2.1
Medication: Blood pressure	4.9	9.4	9.6	-3.0	3.1
High blood pressure	4.8	13.5	16.2	-4.0	3.3
Trunk fat-free mass	4.8	27.3	50.6	-2.0	7.1
Trunk predicted mass	4.7	27.0	50.1	-2.0	7.1
Allergy or Eczema	4.6	12.0	22.4	-1.3	4.7
Mouth/teeth dental problems: Bleeding gums	4.6	6.0	6.2	2.4	-2.5
Crohns Disease (2012)	4.5	7.2	11.5	-1.7	3.4
Medication: Amlodipine	4.5	6.3	6.4	-2.5	2.5
Supplements: Fish oil (including cod liver oil)	4.5	5.8	8.1	-2.9	1.9
Glaucoma (self-reported)	4.4	5.2	6.6	-2.0	2.6
Vascular/heart problems diagnosed by doctor	4.3	11.7	14.7	3.8	-3.0
Height	4.2	81.7	161.3	-1.5	12.7
Pulse rate, automated reading	4.2	13.6	16.1	4.0	-3.3
Whole body fat-free mass	4.2	23.7	42.6	-2.2	6.5
Father’s age at death	4.1	5.5	6.0	2.4	-2.2
Mouth/teeth dental problems: Loose teeth	4.1	4.9	5.0	2.2	-2.2
Handedness (chirality/laterality): Left-handed	4.0	4.8	6.7	-2.6	1.7
Medication: Blood pressure	3.9	6.9	7.1	-2.6	2.7
Whole body water mass	3.9	22.3	40.5	-2.0	6.4
Basal metabolic rate	3.9	21.5	38.1	-2.2	6.2
Alcohol drinker status: Never	3.7	4.4	6.2	-2.5	1.6
Arm fat-free mass (left)	3.7	18.8	33.8	-1.9	5.8
Crohns Disease (2017)	3.6	7.9	12.7	-1.7	3.6
Birth weight of first child	3.6	6.4	11.4	-1.2	3.4
Sensitivity / hurt feelings	3.5	5.9	6.1	2.4	-2.5
Leg fat-free mass (left)	3.5	18.6	31.5	-2.4	5.6
High blood pressure (mother)	3.5	4.8	8.5	-1.1	2.9
Leg predicted mass (left)	3.5	18.8	31.7	-2.4	5.6
Wheeze or whistling in the chest in last year	3.5	6.3	7.3	-2.3	2.7
Long-standing illness, disability or infirmity	3.5	5.3	6.6	-2.0	2.6
Arm predicted mass (left)	3.5	17.7	32.3	-1.8	5.7
Systolic Blood Pressure	3.4	17.0	23.3	-3.3	4.8
Ever smoked	3.4	5.9	8.5	2.9	-1.8
Heel bone mineral density (BMD) T-score, automated (right)	3.3	7.5	8.3	2.6	-2.9
Falls in the last year	3.2	4.4	7.0	-2.6	1.3
Leg fat-free mass (right)	3.2	17.2	29.9	-2.1	5.5
Osteoarthritis (self-reported)	3.2	4.2	7.2	-2.7	1.1
Leg predicted mass (right)	3.2	16.9	29.3	-2.1	5.4
Medication: Omeprazole (e.g. Zanprol)	3.2	3.9	6.8	1.0	-2.6
Qualifications: O levels/GCSEs or equivalent	3.1	5.0	6.5	-1.9	2.5
Arm fat-free mass (right)	3.1	15.7	29.8	-1.3	5.5
Eye problems/disorders: Glaucoma	3.1	3.7	4.5	-1.7	2.1
Cardiovascular Disease	3.0	9.8	10.4	-3.0	3.2
Ever used hormone-replacement therapy (HRT)	3.0	3.8	6.7	-0.9	-2.6
Heart disease (mother)	3.0	3.7	5.5	-2.3	1.4
Arm predicted mass (right)	3.0	15.5	28.9	-1.4	5.4
Heel bone mineral density (BMD) T-score, automated (left)	2.9	6.6	8.8	2.1	-3.0
Time employed in main current job	2.9	3.4	3.4	1.8	-1.8
Nervous feelings	2.8	5.2	5.9	2.1	-2.4
Chronic bronchitis/emphysema (mother)	2.8	3.2	3.4	1.8	-1.8
Number of full brothers	2.8	3.6	4.2	-1.7	2.1
Medication: Ventolin 100micrograms inhaler	2.7	3.5	4.9	-2.2	1.4
Guilty feelings	2.7	4.0	4.9	1.8	-2.2
Ulcerative Colitis	2.6	3.8	6.5	1.1	-2.6
Sitting height	2.6	18.3	36.0	0.8	6.0
Frequency of tenseness / restlessness in last 2 weeks	2.6	4.0	4.6	2.1	-1.8
Forced expiratory volume in 1-second (FEV1), predicted	2.6	5.3	9.4	-1.1	3.1
Intelligence (Savage-Jansen 2018)	2.5	7.5	13.2	-1.4	3.6
Overall health rating	2.5	5.3	7.0	-2.6	1.9
HDL Cholesterol	2.4	4.0	4.9	1.7	-2.2
Vitamin and mineral supplements	2.4	3.2	5.5	2.3	-1.0
Weight	2.4	11.6	19.0	-2.1	4.4
Depression (self-reported)	2.4	2.8	4.2	1.2	-2.1
Seen doctor (GP) for nerves, anxiety, tension or depression	2.4	3.6	3.9	1.8	-2.0
Qualifications: College or University degree	2.4	7.6	13.4	-1.3	3.7
Alcohol intake frequency.	2.4	5.6	6.3	-2.5	2.2
Hearing aid user	2.4	2.7	3.4	1.9	-1.4
Medication: Omeprazole	2.3	2.8	5.2	0.6	-2.3
Diastolic blood pressure, automated reading	2.3	7.2	9.2	-2.3	3.0
Neuroticism (Nagel 2018)	2.2	5.1	5.3	2.3	-2.2
Reaction Time	2.2	4.2	7.0	1.2	-2.6
Illnesses of mother	2.2	2.7	4.2	1.1	-2.0
Exposure to tobacco smoke at home	2.2	2.5	3.1	-1.4	1.8
Ever highly irritable/argumentative for 2 days	2.2	2.7	3.5	1.4	-1.9
Qualifications: nursing, teaching	2.2	3.4	5.2	-1.3	2.3
Myopia	2.2	3.2	3.5	-1.7	1.9
Ever had hysterectomy (womb removed)	2.1	2.3	4.4	2.1	-0.5
Pulse rate	2.1	3.6	4.3	1.7	-2.1
Medication for cholesterol, blood pressure or diabetes	2.1	3.4	4.4	1.6	-2.1
Health satisfaction	2.1	2.7	3.0	-1.5	1.7
Angina	2.0	2.6	3.1	-1.8	1.5
Hip circumference	2.0	8.5	11.2	-2.4	3.4
Prospective memory result	2.0	2.4	4.7	-0.3	-2.2
Birth weight	2.0	4.4	7.6	-1.1	2.8
Angina (self-reported)	2.0	2.6	2.8	-1.7	1.6
Mean time to correctly identify matches	2.0	3.7	7.5	0.2	-2.7
Verbal and Numeric Reasoning (VNR)	1.9	4.6	9.1	0.2	3.0
Neuroticism	1.9	4.6	6.2	1.7	-2.5
Fluid intelligence score	1.9	4.0	7.8	0.3	2.8
Worry too long after embarrassment	1.9	3.2	3.5	1.7	-1.9
Medication: Bendroflumethiazide	1.9	2.9	3.2	-1.8	1.6
Medication: Lisinopril	1.9	2.4	3.6	-1.1	1.9
Forced expiratory volume in 1-second (FEV1), Best measure	1.8	5.6	9.6	-1.3	3.1
Comparative height size at age 10	1.8	10.0	19.8	-0.5	4.5
Ulcerative Colitis (UC)	1.7	3.2	4.6	1.4	-2.2
Chronotype (morning person)	1.7	3.9	6.4	-1.2	2.5
Systolic blood pressure, automated reading	1.7	5.0	5.2	-2.3	2.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.3	4.1	2.0	-0.7
Pulse wave Arterial Stiffness index	1.7	2.0	3.6	-1.9	0.6
Average weekly champagne plus white wine intake	1.7	2.3	3.6	1.9	1.0
Neuroticism (2016)	1.6	2.3	2.7	1.6	-1.4
Smoking Status	1.6	3.7	4.9	1.6	-2.2
Mouth/teeth dental problems	1.6	2.5	4.1	-1.0	2.0
Qualifications: A levels/AS levels or equivalent	1.6	3.6	7.2	-0.2	2.7
Tense / ‘highly strung’	1.6	2.6	3.7	1.9	-1.3
Frequency of depressed mood in last 2 weeks	1.5	2.1	3.5	1.9	-0.8
Had menopause	1.5	1.8	1.8	-1.4	-1.4
Medication: Paracetamol	1.5	2.5	4.8	0.5	-2.2
High blood pressure (siblings)	1.5	2.1	4.2	-0.2	2.1
Illnesses of father: Heart disease	1.5	2.1	4.2	2.0	-0.0
Miserableness	1.5	2.7	3.0	1.7	-1.5
Lung FEV1/FVC ratio	1.4	6.9	11.1	-3.3	1.6
Number of treatments/medications taken	1.4	2.6	3.0	-1.7	1.5
Bilateral oophorectomy (both ovaries removed)	1.4	1.6	2.8	1.7	0.7
Waist circumference	1.4	5.1	6.9	-2.6	1.8
Noisy workplace	1.4	1.8	1.9	1.3	-1.4
Length of working week for main job	1.4	1.6	2.9	1.7	-0.5
Suffer from ‘nerves’	1.4	2.2	3.8	0.7	-1.9
Smoking status: Current	1.4	2.1	3.3	1.8	-1.0
Current tobacco smoking	1.3	2.2	3.0	1.7	-1.1
Diverticular disease/diverticulitis (self-reported)	1.3	1.6	2.8	1.7	-0.6
Forced vital capacity (FVC), Best measure	1.3	4.9	9.3	-0.7	3.0
Mood swings	1.3	2.4	4.8	-0.2	-2.2
Commuting to job workplace: Walk	1.3	1.4	1.5	1.2	-1.1
Illnesses of father: None of the above (group 1)	1.3	1.6	3.1	-0.0	-1.8
Number of operations (self-reported)	1.3	2.0	3.4	0.7	1.8
Qualifications: CSEs or equivalent	1.2	1.6	3.2	-0.2	-1.8
Medication: Ramipril	1.2	1.5	2.3	-0.8	1.5
Hair/balding pattern: Pattern 3	1.2	1.8	2.8	-0.9	-1.7
Lung cancer (father)	1.2	1.5	1.7	-1.1	1.3
Breastfed as a baby	1.2	1.5	1.6	1.3	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	2.7	0.2	-1.6
Ever had bowel cancer screening	1.2	1.4	1.9	-1.0	-1.4
Depressed Affect (Nagel 2018)	1.1	2.3	3.6	1.0	-1.9
Schizophrenia vs Biploar Disorder	1.1	1.4	2.8	0.2	-1.7
Worry (Nagel 2018)	1.1	2.4	3.2	1.3	-1.8
Body Mass Index (BMI) (2010)	1.1	1.5	1.8	-1.1	1.3
Fasting Glucose	1.1	1.4	1.9	-0.9	1.4
Medication for hormone replacement therapy	1.1	1.3	1.8	0.8	-1.4
Chronic bronchitis/emphysema (father)	1.1	1.3	2.4	-0.3	1.6
Trunk fat mass	1.1	4.8	5.3	-2.3	2.1
Pulse wave reflection index	1.1	1.3	2.5	-1.6	0.4
Gout (self-reported)	1.1	1.5	2.9	1.7	0.1
Comparative body size at age 10	1.1	3.2	5.1	1.1	-2.2
Medication: Atorvastatin	1.1	1.4	2.2	-0.7	1.5
Illnesses of father: High blood pressure	1.1	1.4	2.3	1.5	0.6
Diabetes (father)	1.0	1.3	2.1	-1.4	0.7
Forced expiratory volume in 1-second (FEV1)	1.0	3.4	6.5	-0.5	2.5
Arm fat mass (right)	1.0	4.0	5.0	-2.2	1.8
Pulse wave peak to peak time	1.0	1.1	2.3	1.5	0.2
Whole body fat mass	1.0	4.3	5.4	-2.3	1.8
Number of self-reported non-cancer illnesses	1.0	1.8	2.9	-0.8	1.7
Serious illness, injury or assault to yourself	0.9	1.1	1.9	-0.6	1.4
Number of incorrect matches in round	0.9	1.5	2.1	-0.9	-1.4
Hearing difficulty/problems with background noise	0.9	1.4	1.5	1.1	-1.2
Forced vital capacity (FVC)	0.9	3.4	6.7	0.2	2.6
Exposure to tobacco smoke outside home	0.9	1.2	2.3	-1.5	0.4
Age at last live birth	0.9	1.2	1.4	1.0	1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	1.7	0.7	-1.3
Financial situation satisfaction	0.9	1.1	1.6	1.3	-0.8
Commuting to job workplace: Public transport	0.9	1.0	1.8	0.5	1.3
Pain experienced in last month	0.9	1.5	2.1	1.5	-0.9
Alzheimer’s Disease (including proxy)	0.8	1.2	1.9	1.4	-0.6
Breast Cancer	0.8	1.9	3.7	1.9	0.2
Bipolar Disorder (2011)	0.8	0.7	1.1	-1.0	0.7
Blood Eosinophil Count	0.8	6.0	12.1	0.1	3.5
Supplements: Zinc	0.8	0.8	1.2	-1.1	0.7
Medication: Levothyroxine sodium	0.8	1.3	2.5	1.6	-0.4
Neuroticism score	0.8	1.6	2.2	1.0	-1.5
Knee pain experienced in last month	0.8	1.3	1.9	-0.9	1.4
Medication for cholesterol	0.8	1.3	1.8	1.4	-0.8
Medication: Paracetamol	0.8	1.2	2.5	-0.1	-1.6
Ever had prostate specific antigen (PSA) test	0.8	0.9	1.0	-0.9	1.0
Schizophrenia (2014)	0.7	1.6	3.0	-1.7	-0.5
Other serious medical condition/disability diagnosed by doctor	0.7	0.8	1.2	-0.7	1.1
Average weekly fortified wine intake	0.7	0.8	1.6	1.3	0.2
Maternal smoking around birth	0.7	1.0	1.4	0.8	-1.2
Past tobacco smoking	0.7	1.4	2.3	-1.5	0.6
Financial difficulties in last 2 years	0.7	1.0	1.3	1.2	-0.8
Illnesses of siblings	0.7	1.0	2.0	0.0	-1.4
Happiness	0.7	0.8	0.9	0.8	0.9
Medication: Lansoprazole	0.7	0.8	1.5	-0.3	-1.2
Medication for pain relief, constipation, heartburn	0.7	1.2	2.3	0.5	1.5
Loneliness, isolation	0.7	0.9	1.4	1.2	-0.7
Arm fat mass (left)	0.7	2.9	3.5	-1.9	1.5
Fractured/broken bones in last 5 years	0.7	0.9	1.7	0.4	-1.3
Leg fat mass (left)	0.7	2.8	4.0	-2.0	1.2
Alzheimer’s Disease (in mother)	0.6	0.8	1.4	1.2	0.3
Ovarian Cancer	0.6	0.8	1.0	1.0	-0.8
Age at First Birth	0.6	0.9	1.5	-1.2	0.5
Rheumatoid Arthritis	0.6	0.8	1.5	-1.2	-0.3
Hearing difficulty/problems: Yes	0.6	1.0	1.3	1.1	-0.8
Medication: Co-codamol	0.6	0.7	1.3	1.1	0.2
Supplements: Glucosamine	0.6	0.8	1.1	-0.7	1.1
Alcohol usually taken with meals	0.6	1.0	1.1	1.0	-1.0
Arm fat percentage (right)	0.6	2.2	4.4	-2.1	-0.1
Loud music exposure frequency	0.6	0.7	0.7	0.8	-0.9
Blood clot in the leg (DVT)	0.6	0.7	1.4	0.3	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	1.5	1.2	-0.4
Medication: Allopurinol	0.6	0.8	1.5	1.2	0.2
Leg fat mass (right)	0.6	2.5	3.6	-1.9	1.1
Average weekly beer plus cider intake	0.6	0.8	1.1	-0.7	-1.0
Basal cell carcinoma (self-reported)	0.6	0.7	1.2	-1.1	0.5
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	1.4	0.4	-1.2
Prostate Cancer	0.5	0.7	1.3	0.3	-1.1
Mean Putamen Volume	0.5	0.6	0.9	-0.5	0.9
HbA1C	0.5	0.5	0.7	0.9	0.6
Type 2 Diabetes (T2D) (2012)	0.5	0.5	1.0	-0.2	1.0
Waist Hip Ratio (WHR)	0.5	2.1	2.7	1.6	-1.2
Lung FVC	0.5	2.3	4.6	0.2	-2.2
Relative age of first facial hair	0.5	0.9	1.3	-0.8	1.1
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	1.1	-1.1	0.0
Townsend deprivation index at recruitment	0.5	0.7	1.2	-1.1	0.4
Age when periods started (menarche)	0.5	1.2	2.1	-1.5	-0.5
Had other major operations	0.5	0.6	0.9	-0.5	1.0
Alcohol intake versus 10 years previously	0.5	0.8	1.2	-1.1	0.7
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.9	1.7	0.1	-1.3
Hair/balding pattern: Pattern 4	0.5	1.1	1.7	0.8	-1.3
Emphysema/chronic bronchitis	0.5	0.5	1.0	0.2	1.0
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	0.9	-1.0	-0.4
Supplements: Vitamin C	0.5	0.6	0.9	-1.0	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	2.0	-1.4	0.1
Ever taken oral contraceptive pill	0.5	0.6	0.7	0.7	0.8
High cholesterol (Self-reported)	0.5	0.8	0.8	0.9	-0.9
Unable to work because of sickness or disability	0.5	0.6	0.8	-0.6	0.9
Commuting to job workplace: Cycle	0.5	0.6	1.1	-1.1	0.3
Heart attack/myocardial infarction (self-reported)	0.5	0.7	0.9	-0.9	0.7
Bipolar Disorder or Schizophrenia	0.4	1.0	1.9	-1.4	0.4
Depression (Nagel 2018)	0.4	0.6	1.2	1.1	-0.3
Hand grip strength (left)	0.4	1.0	1.6	0.5	-1.3
Trunk fat percentage	0.4	1.7	3.3	-1.8	0.2
Fed-up feelings	0.4	0.7	1.3	0.3	-1.1
Taking other prescription medications	0.4	0.5	0.7	-0.6	0.9
Stomach or abdominal pain in last month	0.4	0.6	1.0	0.2	1.0
Heart attack	0.4	0.5	0.7	-0.8	0.5
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	0.9	0.4	0.9
Peak expiratory flow (PEF)	0.4	1.0	1.8	-0.5	1.3
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	1.6	1.3	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	0.6	0.6	0.8
Age at first live birth	0.4	0.8	1.6	-0.0	1.2
Neck or shoulder pain in last month	0.4	0.6	0.8	0.6	-0.9
Illnesses of siblings: Diabetes	0.4	0.5	0.8	0.9	0.4
Arm fat percentage (left)	0.4	1.6	2.8	-1.7	-0.6
Eye problems/disorders: Cataract	0.4	0.5	0.8	-0.9	-0.3
Medication: Gliclazide	0.4	0.4	0.5	-0.7	0.6
Leg fat percentage (left)	0.4	1.5	2.0	-1.0	-1.4
Irritability	0.4	0.7	1.4	0.0	1.2
Ever depressed for a whole week	0.4	0.4	0.6	-0.5	-0.8
Cholesterol lowering medication	0.4	0.6	1.1	-0.3	-1.1
Bipolar Disorder (2018)	0.3	0.4	0.4	-0.7	0.6
Schizophrenia (2018)	0.3	0.7	1.4	-1.2	-0.0
Blood White Count	0.3	2.4	3.2	-1.3	1.8
Hypothyroidism (self reported)	0.3	0.8	1.3	1.1	0.5
Medication: Metformin	0.3	0.4	0.7	-0.8	0.3
Impedance of leg (left)	0.3	1.3	1.9	0.8	-1.4
Pain all over the body in last month	0.3	0.3	0.6	0.2	-0.8
Diabetes (self-reported)	0.3	0.4	0.8	-0.3	-0.9
Headache pain in last month	0.3	0.4	0.5	0.7	0.6
Body fat percentage	0.3	1.4	2.5	-1.6	-0.4
Leg fat percentage (right)	0.3	1.2	1.8	-0.8	-1.3
Eye problems/disorders: None of the above	0.3	0.3	0.6	0.8	-0.3
Number of full sisters	0.3	0.3	0.5	-0.4	-0.7
Leg pain on walking	0.3	0.4	0.9	0.9	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	0.5	-0.7	-0.4
Breast cancer (self-reported)	0.3	0.4	0.6	0.5	-0.8
Wears glasses or contact lenses	0.3	0.4	0.7	0.1	0.9
Tinnitus: Yes, now most or all of the time	0.3	0.4	0.8	0.1	-0.9
Age started oral contraceptive pill	0.3	0.4	0.5	-0.5	-0.7
BMI	0.2	0.9	1.1	-1.1	-0.8
Severe depression (siblings)	0.2	0.2	0.4	-0.6	-0.0
Impedance of leg (right)	0.2	0.7	0.9	0.7	-1.0
Relative age voice broke	0.2	0.4	0.6	-0.3	0.8
Body mass index (BMI)	0.2	0.9	1.7	-1.3	-0.2
Worrier / anxious feelings	0.2	0.4	0.7	0.4	-0.9
Number of live births	0.2	0.3	0.4	0.6	0.5
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.4	0.6	-0.0
Medication: Cholesterol lowering	0.2	0.3	0.5	0.4	0.7
Shortness of breath walking on level ground	0.2	0.2	0.2	0.5	-0.4
Medication: Seretide 50 evohaler	0.2	0.2	0.4	0.7	0.1
Chest pain or discomfort	0.2	0.3	0.4	-0.5	0.6
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.4	0.3	-0.6
Risk taking	0.2	0.3	0.5	-0.7	-0.3
Alcohol drinker status: Previous	0.2	0.2	0.2	0.4	-0.5
Alzheimer’s Disease (in father)	0.1	0.1	0.1	0.1	0.3
Irritable Bowel Disease (IBD)	0.1	0.2	0.4	-0.0	0.7
Coronary Artery Disease (CAD)	0.1	0.1	0.2	-0.5	-0.1
LDL Cholesterol	0.1	0.2	0.3	0.5	-0.3
Primary Biliary Cirrhosis	0.1	0.1	0.2	0.4	-0.1
Tanning	0.1	0.7	1.2	1.1	-0.3
Diabetes (mother)	0.1	0.1	0.2	0.5	0.1
Pack years adult smoking proportion	0.1	0.1	0.2	0.4	0.1
Hair/balding pattern: Pattern 2	0.1	0.1	0.2	0.2	0.4
Impedance of arm (right)	0.1	0.3	0.6	-0.8	0.1
Mouth/teeth dental problems: Dentures	0.1	0.2	0.4	0.2	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.2	-0.1	-0.4
Impedance of arm (left)	0.1	0.2	0.5	-0.1	-0.7
Migraine (self-reported)	0.1	0.1	0.2	-0.5	-0.0
Medication: Ibuprofen	0.1	0.1	0.1	-0.2	-0.4
Family relationship satisfaction	0.1	0.2	0.3	0.1	0.6
Commuting to job workplace: Car/motor vehicle	0.1	0.2	0.3	-0.5	-0.2
Medication: Aspirin	0.1	0.1	0.2	-0.4	0.1
Smoking status: Previous	0.1	0.1	0.2	0.5	-0.3
Average weekly red wine intake	0.1	0.1	0.3	-0.5	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.2	-0.0	0.4
Friendships satisfaction	0.1	0.2	0.3	0.5	-0.0
Back pain experienced in last month	0.1	0.2	0.3	0.2	-0.5
Osteoporosis (self-reported)	0.1	0.1	0.2	-0.1	0.5
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.1	-0.4	-0.0
Supplements: Calcium	0.1	0.2	0.3	0.1	-0.6
Heart disease (siblings)	0.1	0.1	0.1	-0.4	-0.3
Pack years of smoking	0.1	0.1	0.3	-0.2	0.5
Impedance of whole body	0.1	0.3	0.5	0.3	-0.7
Major Depression (MDD)	0.0	0.1	0.1	0.3	0.1
Lupus	0.0	0.0	0.0	-0.0	0.0
Type 2 Diabetes (T2D) (2018)	0.0	0.1	0.1	0.3	-0.2
Hair Pigment	0.0	1.3	1.6	-1.3	-1.0
Average weekly spirits intake	0.0	0.1	0.1	-0.1	0.3
Hand grip strength (right)	0.0	0.1	0.1	0.3	-0.1
Medication: Atenolol	0.0	0.0	0.0	-0.1	-0.1
Medication: Simvastatin	0.0	0.0	0.0	0.2	-0.0
Had major operations	0.0	0.0	0.1	-0.3	0.2
Diabetes diagnosed by doctor	0.0	0.0	0.0	-0.2	-0.2
Medication: Aspirin	0.0	0.1	0.1	-0.3	0.2
Mother’s age at death	0.0	0.0	0.0	-0.2	-0.1

Hub : Genes

C3orf63

Models

Trait associations