[Hub]/) : Traits : Whole body fat-free mass : ← →

chr1:35,908,451-37,494,602

Best TWAS P=3.71e-12 · Best GWAS P=5.74e-12 conditioned to 0.509

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Artery Aorta	RP11-268J15.5	0.20	0.14	lasso	4	0.13	1.2e-07	-6.7	-7.0	3.7e-12	0.31	0.01	0.99	TRUE
11	GTEx	Whole Blood	MAP7D1	0.12	0.09	lasso	3	0.09	8.3e-09	-5.5	-5.6	2.7e-08	0.78	0.91	0.09	TRUE
5	GTEx	Lung	SH3D21	0.12	0.02	lasso	1	0.03	2.1e-03	-6.7	6.7	2.3e-11	-0.29	0.01	0.98	FALSE
7	GTEx	Skin Sun Exposed Lower leg	SH3D21	0.15	0.07	lasso	5	0.08	4.7e-07	6.6	6.7	2.9e-11	-0.37	0.01	0.98	FALSE
13	METSIM	Adipose	SH3D21	0.05	0.05	lasso	3	0.04	5.1e-07	-6.7	6.6	3.6e-11	-0.29	0.01	0.99	FALSE
9	GTEx	Thyroid	RP11-268J15.5	0.13	0.12	lasso	4	0.10	2.7e-08	-6.7	-6.6	5.3e-11	0.29	0.01	0.99	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	SH3D21	0.28	0.18	lasso	5	0.19	4.1e-24	-6.7	6.5	5.9e-11	-0.28	0.00	1.00	FALSE
4	GTEx	Lung	RP11-268J15.5	0.27	0.16	lasso	4	0.15	1.6e-11	-6.7	-6.5	1.1e-10	0.28	0.01	0.99	FALSE
1	GTEx	Adipose Visceral Omentum	RP11-268J15.5	0.17	0.14	lasso	2	0.11	2.8e-06	-6.7	-6.3	2.3e-10	0.25	0.01	0.99	FALSE
19	The Cancer Genome Atlas	Colon Adenocarcinoma	MAP7D1	0.06	0.01	blup	33	0.04	1.3e-03	-5.6	-6.3	2.7e-10	0.75	0.02	0.44	FALSE
3	GTEx	Artery Tibial	RP11-268J15.5	0.11	0.10	lasso	3	0.08	4.1e-07	-6.7	-6.3	3.3e-10	0.29	0.01	0.99	FALSE
12	METSIM	Adipose	RP11-268J15.5	0.05	0.06	lasso	3	0.05	4.0e-08	-6.7	-6.2	4.3e-10	0.29	0.01	0.99	FALSE
6	GTEx	Nerve Tibial	RP11-268J15.5	0.18	0.09	lasso	5	0.08	1.5e-06	-6.7	-6.0	1.5e-09	0.25	0.01	0.99	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	RP11-268J15.5	0.21	0.16	lasso	5	0.17	4.3e-21	-6.7	-6.0	1.7e-09	0.21	0.00	1.00	FALSE
18	The Cancer Genome Atlas	Colon Adenocarcinoma	FAM176B	0.14	0.04	blup	23	0.04	1.8e-03	-6.7	5.8	6.9e-09	-0.34	0.00	0.96	FALSE
10	GTEx	Thyroid	SH3D21	0.14	0.03	lasso	4	0.05	6.6e-05	-6.7	5.8	7.5e-09	-0.27	0.01	0.98	FALSE
20	The Cancer Genome Atlas	Colon Adenocarcinoma	TRAPPC3	0.07	0.02	blup	38	0.03	5.7e-03	-4.9	-5.5	2.9e-08	0.69	0.05	0.40	FALSE
17	YFS	Blood	MAP7D1	0.04	0.03	lasso	7	0.03	8.3e-10	-5.4	-5.5	3.7e-08	0.78	0.91	0.09	FALSE
8	GTEx	Thyroid	TRAPPC3	0.10	0.08	lasso	3	0.08	7.2e-07	-5.4	5.5	3.9e-08	-0.76	0.33	0.63	FALSE
14	NTR	Blood	MAP7D1	0.02	0.03	lasso	3	0.02	3.4e-08	-5.4	-5.4	5.4e-08	0.76	0.31	0.69	FALSE