[Hub]/) : Traits : Whole body water mass :

chr6:25,266,147-26,689,223

Best TWAS P=1.14e-17 · Best GWAS P=3.56e-30 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous U91328.19 0.40 0.46 lasso 8 0.46 4.2e-41 -6.5 6.5 8.5e-11 -0.32 1.00 0.00 FALSE
2 GTEx Adipose Visceral Omentum U91328.19 0.21 0.25 lasso 8 0.27 3.7e-14 -6.5 6.8 7.5e-12 -0.35 1.00 0.00 FALSE
3 GTEx Adrenal Gland U91328.19 0.28 0.12 lasso 10 0.14 1.3e-05 -7.1 8.6 1.1e-17 -0.42 0.94 0.00 TRUE
4 GTEx Artery Aorta U91328.19 0.32 0.24 lasso 7 0.25 8.3e-14 -7.1 7.7 1.4e-14 -0.38 1.00 0.00 FALSE
5 GTEx Artery Tibial TRIM38 0.08 0.00 lasso 9 0.00 3.7e-01 5.1 5.3 1.0e-07 -0.18 0.30 0.04 FALSE
6 GTEx Artery Tibial U91328.19 0.26 0.32 lasso 5 0.31 1.6e-24 -6.5 6.8 9.7e-12 -0.34 1.00 0.00 FALSE
7 GTEx Brain Caudate basal ganglia U91328.19 0.23 0.16 lasso 10 0.16 3.1e-05 -7.5 7.4 1.9e-13 -0.33 0.63 0.15 FALSE
8 GTEx Brain Cerebellar Hemisphere U91328.19 0.47 0.33 enet 44 0.26 2.8e-07 -7.0 7.8 5.3e-15 -0.24 0.98 0.00 FALSE
9 GTEx Brain Cerebellum U91328.19 0.13 0.15 lasso 2 0.09 1.1e-03 -7.2 7.2 8.3e-13 -0.26 0.35 0.04 FALSE
10 GTEx Brain Cortex U91328.19 0.36 0.14 lasso 10 0.15 7.1e-05 -6.1 7.1 9.1e-13 -0.31 0.64 0.04 FALSE
11 GTEx Brain Frontal Cortex BA9 U91328.19 0.17 0.16 lasso 4 0.18 1.8e-05 -6.1 6.4 1.4e-10 -0.31 0.43 0.08 FALSE
12 GTEx Breast Mammary Tissue U91328.19 0.38 0.39 lasso 5 0.38 2.2e-20 -6.5 6.8 9.9e-12 -0.33 1.00 0.00 FALSE
13 GTEx Breast Mammary Tissue (Male) U91328.19 0.35 0.15 enet 25 0.15 2.9e-04 -6.5 6.1 9.5e-10 -0.26 0.38 0.04 FALSE
14 GTEx Breast Mammary Tissue (Female) U91328.19 0.39 0.27 lasso 6 0.23 1.4e-07 -6.5 6.9 6.5e-12 -0.31 0.95 0.00 FALSE
15 GTEx Cells Transformed fibroblasts U91328.19 0.58 0.62 lasso 8 0.60 6.2e-56 -6.5 6.6 3.1e-11 -0.32 1.00 0.00 FALSE
16 GTEx Esophagus Gastroesophageal Junction U91328.20 0.16 0.13 enet 16 0.13 2.0e-05 -4.7 7.8 5.0e-15 -0.42 0.31 0.33 FALSE
17 GTEx Esophagus Gastroesophageal Junction U91328.19 0.28 0.07 lasso 7 0.21 4.3e-08 -6.1 6.7 2.1e-11 -0.33 0.71 0.02 FALSE
18 GTEx Esophagus Mucosa U91328.19 0.45 0.42 lasso 7 0.44 6.3e-32 -6.5 7.2 4.0e-13 -0.36 1.00 0.00 TRUE
19 GTEx Esophagus Muscularis TRIM38 0.06 0.04 lasso 4 0.02 1.7e-02 -7.1 7.7 1.5e-14 -0.34 0.50 0.09 FALSE
20 GTEx Esophagus Muscularis U91328.19 0.36 0.30 lasso 10 0.30 1.7e-18 -7.1 7.5 5.8e-14 -0.38 1.00 0.00 FALSE
21 GTEx Heart Atrial Appendage U91328.19 0.25 0.17 enet 6 0.13 2.0e-06 -6.5 6.8 1.2e-11 -0.34 0.99 0.00 FALSE
22 GTEx Heart Left Ventricle U91328.19 0.20 0.18 lasso 5 0.15 2.4e-08 -6.5 6.2 4.2e-10 -0.29 0.99 0.00 FALSE
23 GTEx Lung U91328.19 0.20 0.22 enet 15 0.24 2.9e-18 -7.3 7.6 2.6e-14 -0.35 1.00 0.00 FALSE
24 GTEx Muscle Skeletal U91328.19 0.28 0.26 enet 15 0.32 1.3e-31 -6.5 7.1 1.2e-12 -0.33 1.00 0.00 FALSE
25 GTEx Nerve Tibial U91328.19 0.46 0.38 lasso 10 0.36 1.4e-26 -6.5 6.5 8.2e-11 -0.32 1.00 0.00 FALSE
26 GTEx Ovary U91328.19 0.37 0.17 enet 18 0.34 4.7e-09 -6.1 8.3 7.7e-17 -0.39 0.74 0.04 FALSE
27 GTEx Prostate U91328.19 0.30 0.39 lasso 2 0.37 3.0e-10 -6.5 6.5 9.5e-11 -0.32 0.95 0.02 FALSE
28 GTEx Skin Not Sun Exposed Suprapubic U91328.19 0.39 0.37 lasso 11 0.34 2.4e-19 -6.5 7.1 1.6e-12 -0.34 1.00 0.00 FALSE
29 GTEx Skin Sun Exposed Lower leg U91328.19 0.29 0.34 lasso 6 0.34 5.6e-29 -6.5 7.0 3.3e-12 -0.32 1.00 0.00 FALSE
30 GTEx Stomach U91328.19 0.17 0.05 lasso 5 0.05 1.7e-03 -6.5 5.6 2.6e-08 -0.29 0.57 0.04 FALSE
31 GTEx Thyroid TRIM38 0.14 0.16 lasso 4 0.17 8.5e-13 -5.3 6.1 1.2e-09 -0.27 1.00 0.00 FALSE
32 GTEx Thyroid U91328.19 0.21 0.17 lasso 5 0.17 6.4e-13 -6.5 6.2 6.6e-10 -0.31 1.00 0.00 FALSE
33 GTEx Thyroid U91328.21 0.08 0.04 lasso 3 0.05 5.5e-05 -5.3 6.0 1.8e-09 -0.25 0.74 0.01 FALSE
34 GTEx Uterus U91328.19 0.38 0.05 enet 21 0.04 6.2e-02 -7.3 6.4 1.3e-10 -0.36 0.13 0.37 TRUE
35 GTEx Vagina U91328.19 0.45 0.27 lasso 4 0.26 9.4e-07 -6.5 6.4 2.0e-10 -0.31 0.65 0.02 FALSE
36 GTEx Whole Blood TRIM38 0.08 0.04 enet 13 0.03 1.4e-03 5.8 5.6 2.1e-08 -0.14 0.79 0.01 TRUE
37 GTEx Whole Blood U91328.21 0.07 0.04 lasso 4 0.04 1.7e-04 5.8 5.7 9.3e-09 -0.13 0.40 0.02 FALSE
38 METSIM Adipose U91328.19 0.19 0.24 lasso 23 0.25 1.7e-36 -6.5 7.3 3.2e-13 -0.33 1.00 0.00 FALSE
39 METSIM Adipose U91328.20 0.07 0.04 bslmm 658 0.04 8.9e-07 -2.8 7.3 3.3e-13 -0.19 0.95 0.01 TRUE
40 YFS Blood TRIM38 0.37 0.31 bslmm 672 0.34 3.8e-115 -7.3 -7.6 2.4e-14 0.29 1.00 0.00 TRUE
41 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SLC17A3 0.03 0.01 lasso 2 0.01 4.9e-02 4.8 -5.2 1.9e-07 0.14 0.13 0.14 FALSE