TWAS hub - TRIM38

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.0768	0.0330	2.5e-03	-0.001	NA	-0.003	NA	-0.001	4.0e-01	NA	7.5e-01	NA	3.7e-01
2	GTEx	Colon Transverse	0.1530	0.0640	3.6e-03	-0.003	NA	0.028	NA	-0.001	4.9e-01	NA	1.7e-02	NA	3.7e-01
3	GTEx	Esophagus Muscularis	0.0610	0.0290	7.4e-03	0.041	NA	0.020	NA	0.022	1.6e-03	NA	2.2e-02	NA	1.7e-02
4	GTEx	Lung	0.0947	0.0388	1.1e-03	0.027	NA	0.042	NA	0.049	3.3e-03	NA	3.3e-04	NA	1.3e-04
5	GTEx	Skin Sun Exposed Lower leg	0.0920	0.0340	2.6e-04	0.002	NA	0.021	NA	0.021	1.9e-01	NA	6.3e-03	NA	6.5e-03
6	GTEx	Thyroid	0.1380	0.0410	3.3e-07	0.158	NA	0.153	NA	0.167	3.6e-12	NA	8.8e-12	NA	8.5e-13
7	GTEx	Whole Blood	0.0750	0.0300	5.9e-04	0.042	NA	0.027	NA	0.025	8.5e-05	NA	1.4e-03	NA	2.0e-03
8	METSIM	Adipose	0.1155	0.0410	5.0e-06	0.040	0.050	0.078	0.054	0.044	1.1e-06	5.6e-08	9.0e-12	1.6e-08	3.3e-07
9	YFS	Blood	0.3708	0.0423	0.0e+00	0.308	0.319	0.337	0.338	0.328	5.7e-103	1.4e-107	6.2e-115	3.8e-115	2.3e-111
10	TCGA	Lung Adenocarcinoma	0.0695	0.0441	5.9e-03	0.009	0.005	0.009	NA	0.016	2.5e-02	7.0e-02	2.8e-02	NA	5.1e-03
11	TCGA	Thyroid Carcinoma	0.2990	0.1030	1.2e-13	0.153	0.150	0.165	NA	0.158	9.6e-15	2.1e-14	7.8e-16	NA	3.2e-15

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Gout (self-reported)	9.5	13.0	56.6	-3.6	-3.9	-2.0	-4.9	-1.3	-2.1	-7.5	-3.1	3.1	-1.2	-1.9
Medication: Allopurinol	6.8	9.0	39.8	-2.4	-2.2	-1.7	-4.0	0.6	-2.6	-6.3	-3.0	2.6	-0.8	-2.6
Asthma	6.4	12.6	27.3	-5.2	-1.8	-3.9	-3.5	-5.1	-2.3	-4.0	-2.5	3.0	-3.4	-2.2
Prospective memory result	6.0	7.4	16.5	4.1	3.5	2.8	2.0	3.3	2.1	2.8	2.1	-2.7	1.8	1.7
Hip circumference	5.9	25.2	72.9	4.4	0.6	8.5	3.7	-5.2	6.8	3.6	-1.5	-7.0	-3.6	4.7
Arm predicted mass (right)	5.7	29.3	69.7	5.7	2.5	8.3	4.2	-3.9	6.8	6.2	-0.5	-8.0	-3.2	4.6
Bipolar Disorder or Schizophrenia	5.6	13.6	44.2	4.0	5.1	1.8	2.7	4.5	1.4	4.1	2.2	-2.6	6.7	1.7
Schizophrenia (2018)	5.6	11.6	44.8	3.6	4.9	0.7	2.2	5.1	0.7	3.0	1.2	-1.8	6.7	1.2
Asthma (self-reported)	5.4	10.8	27.5	-4.9	-1.5	-3.7	-3.1	-5.2	-2.0	-3.3	-2.6	2.6	-3.2	-1.8
Allergy	5.3	12.3	47.5	4.0	0.9	6.9	1.6	1.6	4.4	2.9	1.3	-4.5	0.9	4.0
Weight	5.3	25.9	71.1	4.8	1.1	8.4	3.4	-5.0	6.7	4.4	-1.6	-7.1	-4.2	4.3
Arm fat-free mass (right)	5.3	27.2	64.6	5.5	2.3	8.0	4.0	-3.6	6.6	6.0	-0.5	-7.8	-3.3	4.4
Mouth/teeth dental problems: Dentures	5.2	8.7	21.8	0.8	-2.9	3.4	-1.0	-4.4	3.7	-1.2	-1.9	-2.6	-4.7	2.7
Arm fat-free mass (left)	5.2	26.3	66.9	5.3	2.3	8.2	4.1	-3.4	6.4	5.8	-0.1	-7.7	-3.2	4.1
Average weekly fortified wine intake	5.0	5.9	10.6	-2.8	-3.2	-2.2	-3.3	-0.7	-2.9	-1.9	-0.3	2.5	-1.7	-3.1
Long-standing illness, disability or infirmity	5.0	7.6	12.8	-2.6	-3.6	-2.8	-3.3	-1.7	-2.2	-3.5	-2.4	1.9	-3.1	-2.6
Osteoarthritis (self-reported)	5.0	6.5	15.6	-2.6	-2.5	-3.2	-2.1	-0.3	-2.9	-3.9	-1.1	3.4	-1.1	-2.4
Arm predicted mass (left)	5.0	25.6	65.0	5.2	2.1	8.1	3.9	-3.6	6.3	5.7	-0.4	-7.5	-3.5	3.9
Hayfever, allergic rhinitis or eczema	4.9	10.5	42.2	-2.7	-0.7	-6.5	-0.2	0.3	-4.5	-2.8	-0.4	4.3	0.7	-4.3
Basal metabolic rate	4.8	26.3	66.1	5.4	2.1	8.1	4.1	-3.8	6.4	5.5	-1.0	-7.7	-3.4	4.0
Leg fat mass (left)	4.6	17.9	50.8	2.9	-0.3	7.1	1.9	-5.4	5.8	2.6	-1.7	-5.4	-4.1	3.9
Leg fat mass (right)	4.5	17.5	49.6	2.9	-0.2	7.0	2.0	-5.3	5.8	2.8	-1.6	-5.5	-3.8	3.8
Trunk fat-free mass	4.4	25.2	58.5	5.5	2.6	7.7	4.5	-3.1	6.0	6.0	-0.3	-7.6	-2.9	3.8
Trunk predicted mass	4.4	25.2	58.4	5.5	2.7	7.6	4.6	-3.1	5.9	6.0	-0.3	-7.6	-2.8	3.7
Whole body water mass	4.4	24.8	59.1	5.3	2.3	7.7	4.2	-3.4	6.1	5.6	-0.8	-7.6	-3.0	3.8
Whole body fat-free mass	4.3	24.5	58.8	5.3	2.2	7.7	4.2	-3.5	6.0	5.4	-0.9	-7.6	-3.2	3.8
Stomach or abdominal pain in last month	4.1	5.2	13.3	3.1	1.8	1.4	2.5	1.8	1.4	2.0	2.3	-2.3	3.6	1.7
Whole body fat mass	4.1	16.9	49.4	3.5	-0.3	7.0	2.2	-4.8	5.4	2.9	-1.7	-5.3	-3.9	3.4
Trunk fat mass	4.0	17.3	50.3	3.7	-0.2	7.1	2.1	-4.8	5.3	3.0	-1.7	-5.5	-4.2	3.2
Sensitivity / hurt feelings	3.9	6.6	13.7	3.6	1.6	1.4	3.4	1.9	2.3	3.0	3.7	-3.1	0.2	1.6
Qualifications: A levels/AS levels or equivalent	3.8	8.5	23.9	-4.9	1.7	-3.4	-2.4	-0.7	-4.0	-1.4	-2.1	4.4	1.2	-2.4
Birth weight of first child	3.8	6.8	13.7	3.3	2.1	3.2	2.9	0.9	2.7	3.4	1.1	-3.7	1.3	2.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.8	8.0	39.2	2.5	2.5	-1.1	1.1	6.3	-2.1	1.2	3.1	0.8	4.0	-1.6
Medication: Lisinopril	3.8	4.9	10.4	-3.2	0.6	-2.1	-3.1	-0.1	-3.1	-0.7	-2.2	3.2	0.3	-1.9
Leg fat-free mass (left)	3.7	19.6	48.6	4.3	1.5	7.0	3.2	-4.0	5.5	4.2	-1.7	-6.8	-3.3	3.4
Leg predicted mass (left)	3.7	19.4	48.2	4.4	1.5	6.9	3.2	-3.9	5.5	4.2	-1.6	-6.8	-3.3	3.4
Qualifications: None of the above	3.6	7.7	25.2	5.0	0.0	3.4	2.8	1.7	3.2	1.8	1.7	-3.7	1.2	2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.6	4.2	10.1	3.2	2.2	1.6	2.1	2.7	1.1	2.0	1.7	-2.0	2.1	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	3.5	11.1	33.4	5.1	4.4	0.9	2.7	5.8	-0.2	3.7	2.5	-2.2	3.0	-0.8
Arm fat mass (right)	3.5	14.6	43.2	3.0	-0.2	6.6	2.0	-4.6	5.1	2.7	-1.6	-5.0	-3.3	3.3
Standing height	3.5	34.9	84.5	9.2	5.6	7.8	5.9	-0.2	4.9	8.0	0.8	-8.3	-3.3	1.9
Arm fat mass (left)	3.5	14.3	42.5	3.0	-0.3	6.5	2.0	-4.5	5.1	2.8	-1.6	-5.0	-3.2	3.4
Medication for pain relief, constipation, heartburn	3.4	5.9	15.8	-3.7	-2.8	-1.4	-1.9	-3.0	0.2	-2.7	-2.3	0.9	-4.0	-0.0
Leg fat-free mass (right)	3.4	17.9	43.2	4.4	1.6	6.5	3.2	-3.6	5.2	4.1	-1.6	-6.6	-3.2	3.1
Leg predicted mass (right)	3.4	18.2	43.8	4.5	1.7	6.6	3.3	-3.6	5.2	4.2	-1.5	-6.6	-3.2	3.1
Forced expiratory volume in 1-second (FEV1)	3.2	10.9	35.0	4.7	4.3	0.5	1.8	5.9	-0.9	3.8	3.0	-1.8	3.5	-1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	3.2	4.1	15.6	2.2	1.6	-1.5	2.2	4.0	-0.8	0.7	3.0	-0.9	1.8	-1.2
High cholesterol (Self-reported)	3.2	5.7	12.2	3.5	1.8	3.5	2.1	1.7	2.1	3.0	2.5	-2.7	-0.1	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	3.1	4.1	12.6	3.4	2.7	0.1	1.8	3.5	-0.1	0.9	2.3	-1.4	1.4	-0.7
Depression (self-reported)	3.0	3.6	10.2	1.5	1.8	0.2	1.6	3.2	0.7	2.1	2.5	-0.9	2.8	1.4
Leg fat percentage (left)	3.0	10.7	31.8	1.7	-1.2	5.6	1.2	-4.6	4.8	1.2	-1.0	-3.7	-3.0	3.4
Supplements: Calcium	3.0	3.3	8.0	-2.2	-1.5	-2.8	-0.3	0.1	-2.4	-2.3	-0.5	2.3	-0.5	-2.0
Verbal and Numeric Reasoning (VNR)	2.9	6.9	17.4	-4.2	-3.4	-1.0	-2.5	-3.5	-0.1	-2.5	-1.6	2.5	-3.6	-0.0
Hayfever/allergic rhinitis (self-reported)	2.9	3.8	16.6	-2.0	-0.9	-4.1	-0.5	-0.2	-2.5	-1.4	-0.3	2.6	1.5	-1.8
Leg fat percentage (right)	2.9	10.4	30.4	1.5	-1.2	5.5	1.2	-4.6	4.7	1.2	-0.9	-3.8	-2.9	3.3
Qualifications: College or University degree	2.9	9.2	28.1	-5.3	1.1	-4.4	-3.4	-0.3	-3.7	-1.7	-1.8	3.8	0.8	-2.4
Fluid intelligence score	2.8	5.8	12.8	-3.6	-3.5	-1.4	-2.5	-2.6	-0.7	-2.6	-1.0	2.2	-3.1	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	2.8	4.3	11.1	3.3	2.2	0.9	2.2	2.4	0.8	1.4	2.6	-2.5	2.1	0.3
Medication: Blood pressure	2.8	4.9	13.0	-2.3	0.6	-1.0	-3.0	-0.1	-3.2	-0.1	-3.0	3.6	0.1	-2.4
Qualifications: nursing, teaching	2.8	4.4	12.7	-3.6	-0.1	-2.9	-3.0	-1.4	-1.6	-1.4	-2.2	2.3	-0.7	-1.0
Wears glasses or contact lenses	2.8	3.2	7.8	-2.8	-2.3	-1.8	-1.7	-1.7	-1.6	-2.1	-0.6	1.6	-1.1	-1.6
Body fat percentage	2.7	10.6	31.9	2.3	-1.1	5.7	1.2	-4.4	4.4	1.6	-1.5	-3.7	-3.2	2.9
Trunk fat percentage	2.6	10.5	32.0	2.8	-0.8	5.7	1.3	-4.1	4.2	1.8	-1.4	-3.9	-3.3	2.7
Medication: Levothyroxine sodium	2.6	4.4	9.2	0.4	-0.4	2.8	-0.5	-3.0	3.0	-0.8	-2.1	-2.0	-2.9	2.2
Age at last live birth	2.6	3.7	10.0	-3.0	0.1	-3.2	-1.0	-0.1	-2.7	-1.5	-0.7	1.9	1.7	-2.1
Depression (Nagel 2018)	2.5	3.7	11.6	3.4	3.0	0.1	1.6	2.8	0.5	1.2	1.6	-1.9	1.5	0.0
Body mass index (BMI)	2.5	10.7	28.1	1.0	-1.4	5.3	1.0	-5.0	4.7	1.0	-1.9	-3.7	-2.7	3.5
Alcohol usually taken with meals	2.5	4.0	14.5	-2.4	-1.0	-2.7	-1.8	0.9	-2.2	-2.1	-0.2	3.8	1.4	-0.6
Risk taking	2.5	3.7	14.2	3.3	1.4	-0.3	1.8	3.8	0.4	1.3	1.2	-0.5	2.5	1.0
Worry (Nagel 2018)	2.4	5.0	16.8	2.9	3.3	-0.8	1.8	4.1	0.5	1.4	2.8	-1.0	2.0	0.2
Waist circumference	2.4	8.8	24.7	2.6	-0.3	5.0	2.4	-3.4	3.7	2.8	-0.7	-4.2	-1.3	2.6
Medication: Ventolin 100micrograms inhaler	2.4	3.1	6.6	-1.9	-1.3	-1.5	-1.1	-2.5	-1.0	-2.4	-1.5	1.4	-2.6	-1.1
Knee pain experienced in last month	2.4	3.7	9.3	-1.8	-3.0	-1.6	-1.3	-1.8	-1.1	-2.4	-2.3	1.4	-2.4	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	2.4	5.1	15.9	2.4	1.4	3.2	2.2	-1.5	2.5	1.8	-1.7	-4.0	-0.5	1.6
Ever had prostate specific antigen (PSA) test	2.4	2.8	6.0	2.0	2.0	-0.3	2.4	2.2	-0.6	1.9	1.4	-0.9	2.0	-0.6
Bipolar Disorder (2018)	2.3	3.6	7.8	1.9	2.1	2.0	1.6	0.9	1.3	2.8	2.0	-1.9	2.4	1.2
Ever had hysterectomy (womb removed)	2.3	2.6	9.5	3.1	1.2	1.6	1.0	0.3	1.5	2.4	0.3	-1.7	-1.4	1.0
Maternal smoking around birth	2.3	3.3	7.0	2.3	1.2	2.7	1.4	-0.8	2.6	0.6	-0.1	-2.5	1.0	2.3
Hearing difficulty/problems with background noise	2.3	3.6	8.4	-0.3	0.3	-2.3	-1.3	2.9	-2.4	-1.4	2.5	1.8	2.1	-1.9
Pulse rate, automated reading	2.3	7.4	23.0	-1.6	-1.2	-3.6	-4.8	1.1	-3.3	-2.3	-1.0	2.5	-2.0	-3.5
Comparative height size at age 10	2.3	12.5	36.6	6.0	3.1	4.3	4.0	0.6	1.5	5.3	-0.6	-4.8	-1.3	-0.5
Number of operations (self-reported)	2.3	3.4	9.9	3.1	0.5	2.0	2.7	2.0	1.0	1.5	2.4	-1.5	-0.6	0.1
Other serious medical condition/disability diagnosed by doctor	2.2	2.8	9.6	-0.4	-2.7	-1.9	-0.0	-0.8	-1.6	-1.4	-0.2	0.6	-3.1	-2.1
Severe depression (siblings)	2.2	2.4	4.9	1.9	1.6	1.8	1.6	0.8	1.7	0.5	0.5	-1.5	2.2	1.9
Sitting height	2.2	15.7	39.9	5.0	0.9	6.0	1.8	-2.5	4.7	3.3	-0.6	-6.3	-5.0	2.1
Number of incorrect matches in round	2.2	3.7	12.7	2.6	0.8	-0.1	1.6	2.1	1.1	0.4	3.6	-2.1	2.7	0.9
Frequency of tenseness / restlessness in last 2 weeks	2.2	3.5	9.9	3.2	1.8	0.4	2.9	1.5	0.6	1.2	2.7	-1.9	1.3	-0.1
Forced vital capacity (FVC)	2.2	8.5	23.0	4.2	4.0	0.2	2.0	4.8	-1.5	3.5	2.1	-1.4	3.1	-1.8
Qualifications: O levels/GCSEs or equivalent	2.2	3.5	9.9	-2.9	1.6	-2.2	-0.6	0.5	-3.1	-0.5	0.0	2.2	-0.1	-2.7
Hypothyroidism/myxoedema (self-reported)	2.2	4.2	12.3	0.4	-0.5	2.5	-1.3	-3.1	2.7	-0.6	-1.2	-1.9	-3.5	1.9
Forced vital capacity (FVC), Best measure	2.2	8.2	21.5	4.5	4.1	0.4	2.7	4.6	-0.6	3.3	1.6	-1.6	2.6	-1.2
Had major operations	2.2	2.6	7.2	2.7	-0.4	2.0	2.1	2.0	1.0	1.1	1.9	-1.5	-0.9	-0.2
Medication: Paracetamol	2.1	3.5	14.1	2.5	2.0	0.5	1.8	2.0	-0.2	2.0	1.3	-0.8	3.7	0.2
Age at first live birth	2.1	3.7	9.1	-2.3	1.9	-3.0	-0.2	1.5	-1.9	-1.2	-1.1	2.1	3.0	-0.9
High blood pressure	2.0	5.5	15.4	-2.3	0.4	-0.4	-3.0	0.3	-3.9	-0.4	-2.2	3.7	-0.7	-3.2
High blood pressure (mother)	2.0	2.8	9.4	-1.9	-0.4	-0.3	-3.1	-1.1	-2.4	-0.6	-1.6	1.9	-0.7	-2.1
Ever highly irritable/argumentative for 2 days	2.0	2.4	6.6	2.3	1.4	1.9	2.0	0.0	1.7	0.5	1.3	-2.6	-0.7	0.5
Medication: Amlodipine	2.0	2.7	7.6	-1.6	-0.7	-0.7	-2.5	1.0	-2.8	-0.8	-0.2	2.6	0.6	-2.1
Exposure to tobacco smoke outside home	2.0	2.7	7.2	2.7	1.5	2.0	2.1	-0.8	1.3	2.1	1.0	-1.6	0.3	1.1
Hypertension (Self-reported)	2.0	5.6	15.6	-2.5	0.1	-0.4	-3.2	0.4	-4.0	-0.2	-1.9	3.6	-0.7	-3.4
Ever had bowel cancer screening	2.0	2.4	6.9	1.8	1.0	1.7	2.6	-0.2	1.1	2.2	0.6	-2.1	-0.3	0.9
Medication: Omeprazole	1.9	2.2	8.0	2.1	2.1	-0.3	0.6	2.8	-0.3	1.2	1.4	-0.1	2.0	-0.2
Mouth/teeth dental problems: Mouth ulcers	1.9	3.0	11.0	1.6	3.0	1.1	0.2	1.1	0.7	3.3	0.9	-1.3	2.0	0.7
Guilty feelings	1.9	2.8	8.6	1.8	2.9	-0.3	0.9	1.6	-0.6	2.2	1.3	-0.8	2.8	-0.6
Neuroticism (Nagel 2018)	1.8	4.3	12.2	3.5	3.0	-0.3	2.1	3.0	0.7	1.5	2.2	-1.9	1.4	0.1
Schizophrenia vs Biploar Disorder	1.8	2.4	6.9	-1.1	1.4	-2.3	-0.1	1.1	-2.2	-0.9	0.1	1.8	2.6	-1.0
Nervous feelings	1.8	3.3	9.5	0.1	3.1	-2.9	0.3	2.0	-2.3	-0.4	0.0	1.2	2.3	-1.5
Ever unenthusiastic/disinterested for a whole week	1.8	2.2	5.1	2.1	2.3	0.5	0.2	2.2	1.2	1.8	1.5	-1.2	0.9	0.7
Tense / ‘highly strung’	1.8	3.0	12.7	1.8	1.9	-0.6	0.5	3.6	0.1	0.9	2.5	-0.4	2.2	0.3
Arm fat percentage (left)	1.8	7.1	18.6	1.1	-1.5	4.3	0.6	-4.3	3.5	0.7	-2.1	-2.8	-2.5	2.4
Illnesses of father: High blood pressure	1.8	2.3	10.9	-1.7	0.3	0.5	-1.7	-1.5	-1.4	-0.7	-3.3	1.0	-0.4	-1.5
Alzheimer’s Disease (in mother)	1.7	2.0	7.3	1.9	1.2	0.4	2.7	1.0	0.9	0.2	2.3	-1.5	-0.0	0.5
Arm fat percentage (right)	1.7	6.6	19.8	1.2	-1.1	4.5	0.9	-3.8	3.5	0.7	-1.8	-2.8	-2.4	2.3
Family relationship satisfaction	1.7	2.1	5.1	1.6	2.2	-0.0	2.2	1.9	-0.2	0.9	1.2	0.0	2.1	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	1.7	1.8	4.9	-1.1	0.3	-2.2	0.1	0.1	-2.0	-1.3	-0.8	1.8	0.4	-1.9
Cholesterol lowering medication	1.7	2.5	6.8	1.5	-0.9	2.6	1.5	0.4	1.4	1.3	2.2	-2.5	0.4	0.5
Medication: Omeprazole (e.g. Zanprol)	1.7	2.0	8.8	2.2	1.8	0.1	0.4	3.0	-0.5	0.9	1.1	0.3	1.6	-0.5
Eye problems/disorders: Diabetes related eye disease	1.6	1.8	5.2	1.1	-0.5	1.3	1.8	-1.3	1.4	-0.8	-1.4	-1.2	-2.3	0.6
Bilateral oophorectomy (both ovaries removed)	1.6	1.8	5.9	1.7	0.4	1.3	0.6	-1.7	1.3	2.4	0.2	-1.2	-1.4	0.9
Pain all over the body in last month	1.6	1.7	6.6	1.9	0.3	1.3	2.6	0.5	1.4	0.8	0.4	-1.3	0.5	1.2
Medication: Simvastatin	1.6	2.3	5.7	2.0	-0.3	1.7	1.4	1.3	1.0	1.4	2.4	-2.2	-1.3	-0.1
Neuroticism score	1.6	3.3	8.9	2.4	3.0	-0.8	1.8	2.5	-0.4	1.3	2.2	-1.0	1.8	-0.5
Peak expiratory flow (PEF)	1.6	3.7	11.8	1.7	1.5	0.3	-0.2	3.4	-0.1	3.3	2.0	-1.4	2.5	-0.2
Mouth/teeth dental problems: Bleeding gums	1.6	2.1	6.2	1.1	0.3	-1.0	2.3	1.9	-1.3	0.4	1.4	0.3	2.5	-1.1
Comparative body size at age 10	1.6	4.4	12.6	-0.6	-2.7	1.9	0.2	-3.5	2.6	-0.9	-1.5	-0.8	-3.2	1.9
Reason for reducing amount of alcohol drunk: Health precaution	1.6	1.8	7.1	-0.2	1.2	-0.6	-0.9	1.8	-1.6	1.3	1.1	0.9	2.7	-0.9
Pulse wave peak to peak time	1.6	1.9	4.8	1.1	-0.7	1.9	1.7	-0.7	2.1	0.2	-0.6	-1.6	0.7	2.2
Eye problems/disorders: None of the above	1.6	1.9	11.0	1.0	3.3	1.1	-0.8	0.9	0.2	1.9	0.2	0.1	1.5	0.5
Supplements: Fish oil (including cod liver oil)	1.6	2.1	10.2	-0.0	1.6	-1.6	1.4	0.3	-1.5	1.0	1.4	-0.8	3.2	-0.6
Commuting to job workplace: Cycle	1.6	1.9	5.3	-1.9	0.4	-1.5	-1.8	0.9	-1.2	-0.5	0.7	1.8	2.3	-0.7
Depressed Affect (Nagel 2018)	1.5	3.1	11.3	3.4	1.9	0.6	2.3	1.6	1.1	1.7	1.1	-2.4	0.5	0.1
Heel bone mineral density (BMD) T-score, automated (left)	1.5	3.4	8.9	-0.6	-2.8	2.1	0.3	-3.0	1.6	1.2	-0.5	-1.7	-2.8	1.0
Supplements: Glucosamine	1.5	1.9	6.6	-0.8	0.6	-1.8	0.1	0.4	-2.6	-0.8	1.3	1.4	0.9	-2.2
Length of working week for main job	1.5	1.7	4.1	0.8	-0.9	0.7	0.4	-2.0	1.9	-0.9	-0.2	-1.2	-2.0	1.6
Headache pain in last month	1.5	2.6	8.7	1.4	1.0	-0.9	0.7	2.2	-1.9	1.6	0.9	0.4	3.0	-1.7
Supplements: Vitamin C	1.5	1.8	6.9	-0.4	1.2	-1.7	0.4	1.3	-1.2	-0.1	2.2	0.4	2.6	-0.7
Handedness (chirality/laterality): Left-handed	1.5	1.8	6.9	1.9	0.5	0.0	1.7	2.0	0.3	0.9	2.6	-0.7	1.0	0.0
Commuting to job workplace: Walk	1.5	1.6	4.4	1.6	1.1	0.2	2.1	1.7	-0.1	-0.4	2.0	-0.9	1.3	-0.3
Medication: Blood pressure	1.5	2.9	10.1	-1.2	0.1	0.2	-1.7	1.2	-3.2	-0.9	0.1	2.8	-0.0	-2.8
Diastolic blood pressure, automated reading	1.5	4.8	13.4	-0.3	0.7	-0.6	-2.5	2.9	-3.6	1.1	-0.3	3.7	1.3	-2.8
Diabetes (father)	1.4	1.8	3.7	-0.7	-1.8	-0.8	-0.9	-1.3	-1.9	-1.4	-0.6	1.0	-1.5	-1.8
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.3	12.5	-0.3	-2.1	2.3	0.8	-2.7	1.6	1.0	-0.4	-1.4	-3.5	0.9
Mouth/teeth dental problems	1.4	2.2	6.5	-1.8	-0.3	-1.9	-0.7	0.8	-2.0	-1.5	-1.1	2.5	0.6	-1.3
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.8	4.0	2.0	1.8	-0.6	1.3	1.9	-1.3	0.9	0.6	0.4	1.1	-1.4
Medication: Cholesterol lowering	1.4	2.1	7.6	2.1	1.2	2.0	0.3	0.7	0.6	1.1	1.5	-1.0	-2.8	-0.2
Lung cancer (father)	1.4	1.6	4.5	-0.6	0.2	1.2	-0.9	-2.1	1.4	-1.2	-2.1	-0.6	-0.8	1.5
Average weekly red wine intake	1.4	2.0	5.4	-2.2	0.6	-2.3	-1.5	-0.2	-1.7	-0.9	-0.0	2.1	1.1	-0.3
Ever taken oral contraceptive pill	1.4	1.6	3.0	1.7	1.7	1.6	1.6	-0.3	1.7	1.0	0.3	-1.1	-0.5	1.0
Medication: Bendroflumethiazide	1.4	2.1	6.5	-1.2	1.0	-0.4	-2.5	-0.3	-2.3	0.6	0.2	2.3	0.0	-1.8
Myopia	1.4	2.0	8.0	-2.6	-1.1	-0.2	-1.5	-2.8	-0.3	-0.9	-1.1	0.5	-1.3	-0.1
Crohns Disease (2017)	1.3	2.8	10.6	1.6	2.9	0.1	-0.5	3.2	0.6	0.6	1.1	-0.5	2.5	0.7
Reaction Time	1.3	2.5	7.1	1.5	1.8	-0.4	1.5	2.3	0.6	1.0	2.0	-1.3	2.7	0.8
Vitamin and mineral supplements	1.3	1.8	6.9	1.2	-0.5	2.2	-0.5	-1.1	1.7	0.7	-0.2	-0.4	-2.6	1.1
Past tobacco smoking	1.3	2.3	8.0	-1.0	-2.8	0.1	0.4	-2.1	0.9	-1.1	-1.4	-0.3	-2.8	0.1
Medication: Lansoprazole	1.3	1.5	5.7	2.4	0.2	1.1	0.6	1.5	1.0	1.4	1.7	-0.6	0.2	0.9
Commuting to job workplace: Car/motor vehicle	1.3	1.5	4.3	-0.6	-1.4	-0.3	-2.1	-1.0	-0.8	-0.7	-2.0	1.4	-0.6	-0.5
Loneliness, isolation	1.3	1.7	5.0	1.7	2.2	-0.7	1.8	1.8	-0.8	1.0	0.2	-0.5	1.0	-1.2
Breast cancer (self-reported)	1.3	1.6	4.5	-2.1	-0.0	-1.6	-1.7	-0.3	-1.4	-0.0	-1.3	1.6	0.8	-0.9
Smoking status: Current	1.3	2.1	7.4	2.7	0.0	1.8	1.4	1.7	0.8	1.8	1.1	-1.6	-0.2	0.1
Average weekly champagne plus white wine intake	1.3	1.8	7.4	-2.0	-0.5	-1.5	-1.0	0.8	-1.3	-1.5	-0.4	2.7	0.1	-0.7
Medication: Paracetamol	1.3	2.1	7.2	1.8	1.3	0.3	1.7	1.1	0.0	1.9	1.4	-0.9	2.7	0.4
Major Depression (MDD)	1.2	1.4	3.3	1.3	1.8	0.1	0.8	1.0	0.4	1.0	1.1	-1.8	1.8	0.6
Systolic blood pressure, automated reading	1.2	3.5	10.8	-2.9	-1.4	0.6	-3.1	-0.7	-1.3	-1.2	-1.6	3.3	-1.1	-0.5
Worrier / anxious feelings	1.2	2.2	7.1	1.5	2.7	-0.5	1.9	2.5	-0.0	0.5	1.8	-0.4	1.1	-0.5
Happiness	1.2	1.5	5.5	0.9	2.3	-0.3	1.2	2.3	-0.8	-0.6	0.5	0.0	1.1	-1.1
Breastfed as a baby	1.2	1.5	3.7	0.8	1.2	0.0	1.4	1.5	0.3	1.6	1.9	-0.2	1.8	0.6
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	5.5	0.5	-0.6	0.3	1.6	-0.2	2.3	-0.4	1.1	-2.1	1.4	2.3
Mean time to correctly identify matches	1.2	2.4	4.7	1.4	1.5	-0.4	1.7	2.2	1.1	1.2	1.9	-1.3	2.1	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	3.9	1.6	0.3	1.9	0.9	0.3	0.6	2.0	0.9	-0.6	1.2	0.9
Osteoporosis (self-reported)	1.2	1.5	6.0	-0.8	-2.1	-0.9	-0.2	-0.7	-0.8	-1.3	0.5	0.9	-2.4	-1.0
Financial situation satisfaction	1.2	1.5	5.2	-0.8	1.0	-0.8	-1.1	2.1	-1.1	0.2	0.7	0.6	2.3	-1.0
Vascular/heart problems diagnosed by doctor	1.2	3.4	9.7	1.5	-1.1	-0.3	2.2	-1.0	3.1	-0.1	1.7	-2.9	0.3	2.6
Breast Cancer	1.1	2.7	10.0	-1.6	-1.1	-1.1	-0.8	-1.9	0.2	-2.2	-2.2	0.9	-3.2	-0.2
Angina	1.1	1.5	3.9	0.9	1.0	2.0	-0.4	0.9	1.7	-0.0	-0.1	-0.7	1.6	1.9
Pack years adult smoking proportion	1.1	1.6	5.6	1.6	-1.6	1.6	0.3	-0.2	0.8	0.3	0.6	-1.8	-2.4	-0.2
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	2.9	1.6	0.7	0.9	1.7	0.6	1.5	1.4	0.4	-0.9	0.2	1.3
Impedance of arm (right)	1.1	5.2	12.9	0.5	0.3	-2.9	-0.0	3.5	-3.6	-1.7	0.4	2.8	0.9	-3.4
Pulse wave reflection index	1.1	1.4	3.1	-0.5	0.6	-1.8	-1.2	1.5	-1.6	-0.7	1.0	1.1	-0.3	-1.6
Birth weight	1.1	2.4	8.0	1.5	0.7	0.6	2.1	-1.2	0.9	2.6	0.3	-2.8	-1.2	0.6
Chronic bronchitis/emphysema (mother)	1.1	1.2	2.7	0.4	1.1	0.5	0.7	-1.4	1.1	1.4	-1.4	-1.6	0.4	1.2
Worry too long after embarrassment	1.1	1.8	4.5	-1.7	0.4	-2.1	-0.4	0.7	-1.8	-1.7	0.9	1.3	1.1	-1.5
Mouth/teeth dental problems: Loose teeth	1.1	1.3	2.5	0.2	-0.1	-0.2	1.5	0.0	1.2	1.4	1.5	-1.4	1.1	1.6
Angina (self-reported)	1.1	1.4	3.5	0.7	0.8	1.9	-0.6	0.9	1.7	-0.2	-0.1	-0.8	1.6	1.9
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	5.7	-0.3	-1.5	0.7	-2.4	-1.9	0.3	-0.8	0.2	0.4	-0.9	-0.1
Illnesses of siblings: Diabetes	1.1	1.3	6.9	0.3	-0.3	1.0	-0.2	-1.8	0.8	-0.2	-1.2	-0.8	-2.6	0.4
Mineral and other dietary supplements	1.1	1.5	4.9	0.4	-0.9	1.4	-1.6	-0.2	1.6	-0.4	-1.2	0.5	-2.2	1.1
Ever smoked	1.1	1.9	10.8	0.7	2.2	-0.3	-0.1	1.4	-1.1	0.8	0.5	0.2	3.3	-0.2
Average weekly beer plus cider intake	1.1	1.6	6.0	1.2	0.9	1.1	2.1	-1.0	0.9	0.3	-0.5	-2.4	0.4	1.0
Pack years of smoking	1.1	1.7	5.9	1.8	-1.3	1.6	0.7	-0.0	0.8	0.3	0.9	-1.6	-2.4	-0.3
Intelligence (Savage-Jansen 2018)	1.0	3.0	7.3	-2.2	-2.4	-1.6	-1.1	-1.7	-1.0	-0.8	0.2	2.7	-2.4	-0.8
Age at First Birth	1.0	1.4	6.4	0.3	0.5	1.3	1.0	1.8	0.4	1.1	0.5	-0.5	2.5	1.1
Current tobacco smoking	1.0	1.6	5.3	2.3	-0.2	1.9	1.0	1.2	0.8	1.6	0.6	-1.6	-0.2	0.1
Medication: Atenolol	1.0	1.3	6.3	-0.5	-0.1	2.5	-2.0	-0.3	-0.2	1.2	0.5	-0.1	-1.1	-0.6
Had other major operations	1.0	1.2	2.7	1.5	1.3	1.2	1.6	0.2	0.8	1.1	-0.6	-1.1	1.1	0.6
Pulse wave Arterial Stiffness index	1.0	1.2	3.4	-0.3	1.0	-1.2	-1.3	0.5	-1.6	0.5	0.7	1.0	-1.0	-1.9
High blood pressure (siblings)	1.0	1.5	5.2	-0.9	0.6	-0.3	-0.1	-0.2	-2.3	-0.9	-1.0	1.8	0.7	-2.1
Medication: Seretide 50 evohaler	1.0	1.1	5.1	-0.1	0.6	1.2	0.5	-1.2	0.4	-1.7	-2.2	-0.3	-0.6	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	5.8	-0.3	-1.8	0.0	-1.3	0.2	-0.3	-2.4	0.2	1.2	0.6	0.6
Friendships satisfaction	1.0	1.2	5.4	-0.2	1.9	-0.1	0.7	1.9	-0.3	0.2	0.1	0.0	2.3	0.2
Medication: Atorvastatin	1.0	1.2	5.4	0.9	0.3	2.3	0.3	-0.9	1.3	0.6	0.1	-1.1	-1.4	0.8
Alcohol drinker status: Previous	1.0	1.2	3.4	0.4	0.9	1.0	0.3	-0.9	1.2	0.7	1.9	-0.8	1.1	1.7
Frequency of depressed mood in last 2 weeks	0.9	1.3	3.8	1.9	1.1	-0.9	0.9	1.3	-0.3	1.2	1.6	-1.0	0.7	-0.7
Ever used hormone-replacement therapy (HRT)	0.9	1.1	2.7	1.1	0.8	1.7	1.4	0.9	0.9	1.0	0.7	-0.9	-0.1	1.2
Age when periods started (menarche)	0.9	2.2	5.9	1.6	2.4	0.9	1.3	-0.6	1.1	2.0	1.8	-1.9	0.2	0.9
Alcohol intake versus 10 years previously	0.9	1.3	4.5	-1.2	0.5	-0.6	-1.5	-2.1	-1.1	-0.8	-1.5	0.3	-0.3	-1.3
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	5.4	1.3	2.3	-0.7	1.7	1.2	-0.4	0.6	0.7	-0.8	1.4	-0.8
Impedance of arm (left)	0.9	4.1	10.9	0.5	-0.1	-3.0	-0.4	2.7	-3.3	-1.3	0.2	2.4	0.8	-3.0
Shortness of breath walking on level ground	0.9	1.1	6.5	-0.2	-0.7	0.3	-1.1	-1.3	0.4	-0.6	-1.2	0.1	-2.5	0.2
Suffer from ‘nerves’	0.9	1.4	5.5	1.1	1.4	-0.5	0.9	2.4	-0.5	-0.0	1.8	-0.2	1.5	-0.1
Illness, injury, bereavement, stress in last 2 years	0.9	1.0	3.0	0.9	0.6	0.8	0.7	1.2	0.4	-0.4	1.6	-1.3	-1.7	-0.5
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	2.6	-0.8	-0.1	-1.6	-1.0	0.8	-1.4	-0.6	-0.4	0.3	0.6	-1.2
Noisy workplace	0.8	1.0	4.2	-0.8	-0.3	-0.9	-2.1	-0.5	-1.2	0.0	-1.1	1.0	-0.3	-1.0
Serious illness, injury or assault of a close relative in last 2 years	0.8	1.0	3.2	-1.8	-1.1	-0.8	-0.4	-1.3	-0.4	-0.6	-1.6	0.6	0.5	-0.0
Glaucoma (self-reported)	0.8	0.9	4.6	1.0	-0.1	0.1	1.5	0.9	-0.0	2.1	0.6	-0.9	0.3	-0.0
Health satisfaction	0.8	1.0	2.2	-0.5	1.1	-0.6	-1.1	-0.0	-1.2	-0.1	-1.5	1.4	-1.1	-1.1
Migraine (self-reported)	0.8	1.0	3.0	-1.0	-1.7	-0.3	-0.1	-1.3	-0.6	-0.7	-0.2	0.1	-1.7	-1.1
Medication: Ibuprofen	0.8	1.0	2.5	1.6	1.1	-0.2	1.6	1.3	-0.8	0.8	0.7	0.0	0.1	-1.1
Smoking status: Previous	0.8	1.1	4.8	0.5	2.2	0.4	-1.0	1.0	-0.3	0.7	1.1	0.0	1.9	0.4
Medication for cholesterol	0.8	1.2	4.7	0.3	0.4	-0.6	0.7	-1.0	2.2	0.0	0.1	-1.6	-0.4	1.8
Medication: Gliclazide	0.8	0.9	5.1	0.8	-2.3	0.2	-1.3	-0.2	0.8	-0.4	-0.2	0.5	-0.8	0.8
Miserableness	0.8	1.3	4.8	2.2	0.8	0.4	1.2	-0.1	0.3	1.2	1.2	-2.0	-0.2	-0.5
Mother’s age at death	0.8	1.0	2.5	0.4	0.6	0.2	1.6	0.1	1.4	1.6	0.9	-0.7	1.0	1.2
Tinnitus: Yes, now most or all of the time	0.8	1.0	1.9	0.2	-0.0	-1.3	1.2	0.9	-1.4	1.3	-0.0	0.5	0.9	-1.4
Alzheimer’s Disease (including proxy)	0.7	1.0	4.0	1.6	0.5	0.1	2.0	1.3	0.4	-0.3	0.8	-0.9	-0.7	-0.1
Hand grip strength (left)	0.7	2.0	4.7	0.9	-0.5	2.2	0.5	-0.0	1.9	2.1	1.4	-1.4	-1.6	1.0
Medication for hormone replacement therapy	0.7	0.8	3.6	0.5	1.1	-0.3	0.4	1.9	-0.9	0.5	0.9	1.0	0.8	-0.4
Multivitamins +/- minerals	0.7	0.9	6.3	-0.4	-0.2	-0.8	0.2	1.2	-0.8	-0.2	-0.4	0.1	2.5	-0.3
Diabetes (self-reported)	0.7	1.0	3.1	-0.6	-1.5	-0.3	-1.1	-1.8	-0.1	-1.4	-0.7	0.8	-0.9	0.2
Time employed in main current job	0.7	0.8	2.6	-0.9	-1.1	0.3	-0.3	-1.6	0.2	0.5	-0.8	-0.3	-1.6	0.1
Illnesses of mother	0.7	0.9	2.2	0.3	-1.1	0.5	0.8	-0.7	1.5	-0.9	0.2	-1.3	0.1	1.5
Illnesses of father: Heart disease	0.7	0.9	4.2	-0.0	-2.0	0.8	-0.9	-0.2	1.2	-0.2	0.5	-0.8	-1.3	0.5
Diabetes diagnosed by doctor	0.7	1.2	3.7	-0.2	-1.9	0.4	-0.9	-1.9	0.5	-1.6	-0.1	0.1	-1.3	0.5
Number of self-reported non-cancer illnesses	0.7	1.1	2.0	-0.7	-0.5	-1.3	-0.9	-1.0	-1.4	-0.6	-1.0	1.4	-1.2	-1.2
Pain type(s) experienced in last month: Hip pain	0.7	0.9	4.6	2.1	-0.0	0.7	1.1	0.1	1.0	0.6	0.5	-0.5	-0.9	0.8
Unable to work because of sickness or disability	0.7	0.9	2.7	0.9	-1.7	1.1	0.2	-0.1	0.8	0.7	1.3	-0.5	-1.4	0.4
Alzheimer’s Disease (in father)	0.6	0.6	2.5	-0.5	-0.6	-0.5	-0.1	-0.1	-0.6	-0.4	-1.6	0.5	-1.4	-0.9
Ovarian Cancer	0.6	0.8	3.1	-0.2	1.0	0.1	-0.1	1.1	0.3	-0.5	-1.4	0.6	1.8	1.0
Medication: Metformin	0.6	0.9	3.9	1.5	-0.9	0.8	0.5	-0.2	0.7	0.5	2.0	-0.6	-0.7	0.4
Hand grip strength (right)	0.6	1.5	5.3	1.0	0.4	2.2	0.1	0.3	1.4	2.3	0.9	-1.2	-0.6	0.9
Taking other prescription medications	0.6	0.9	2.4	0.1	-1.5	0.4	0.4	-1.5	0.8	1.0	-1.0	-0.8	-1.1	0.3
Loud music exposure frequency	0.6	0.7	2.6	1.3	0.8	-0.3	0.4	1.6	-0.6	-0.4	0.3	-0.5	0.0	-1.1
Neck or shoulder pain in last month	0.6	0.9	3.6	0.8	0.8	-1.1	0.1	1.5	-1.2	-0.1	0.5	0.1	-0.3	-1.9
Chest pain or discomfort	0.6	0.9	4.0	0.2	-2.0	-0.0	-0.2	0.3	0.4	-1.7	0.3	-0.6	-1.5	-0.0
Medication: Aspirin	0.6	0.7	2.3	1.2	0.5	1.5	-0.1	0.5	0.3	1.0	1.3	-1.0	0.0	-0.2
Eye problems/disorders: Cataract	0.6	0.7	3.1	-0.7	-0.6	-1.2	0.1	-1.2	0.0	-1.8	0.1	0.0	-0.5	0.2
Back pain experienced in last month	0.6	0.8	3.6	1.9	-0.7	0.3	0.7	0.8	-0.3	1.0	1.1	-0.7	-0.2	-1.0
Hearing aid user	0.6	0.6	1.8	0.4	0.6	0.1	0.0	-1.2	0.4	1.2	-0.7	-0.9	-1.3	-0.5
Eye problems/disorders: Glaucoma	0.6	0.7	2.3	0.4	-0.4	-0.3	1.5	1.5	-0.4	1.4	0.2	-0.5	-0.1	-0.7
Fractured/broken bones in last 5 years	0.6	0.8	2.2	-0.8	0.4	-1.1	0.4	0.9	-0.5	-0.9	-0.8	1.5	-1.2	-0.6
Ever depressed for a whole week	0.6	0.7	1.6	1.2	1.1	0.4	0.3	1.3	0.5	1.2	0.6	-1.0	0.7	-0.2
Basal cell carcinoma (self-reported)	0.6	0.7	2.0	-0.2	0.7	-1.2	-0.1	0.8	-1.2	0.7	-0.6	0.8	-0.4	-1.4
Impedance of whole body	0.6	3.2	8.0	1.2	0.5	-2.1	-0.2	2.8	-2.8	-0.6	1.4	2.1	0.6	-2.6
Number of treatments/medications taken	0.5	0.9	3.3	-0.5	-0.5	-0.7	-0.7	-0.2	-1.8	0.9	-0.3	1.3	0.0	-1.5
Supplements: Zinc	0.5	0.6	1.8	-0.8	-0.7	-1.1	0.0	0.6	-0.8	0.0	0.5	-0.1	1.4	-0.9
Medication: Co-codamol	0.5	0.6	1.7	0.3	0.7	0.6	1.3	-1.0	0.8	1.1	-0.4	-0.4	0.0	0.5
Qualifications: CSEs or equivalent	0.5	0.6	2.2	1.1	-0.2	0.1	0.6	-0.9	-0.8	-1.5	0.8	-0.0	-0.6	-0.9
Serious illness, injury or assault to yourself	0.5	0.6	2.1	0.4	-1.4	0.5	-1.5	0.1	0.4	-0.0	-0.9	0.7	0.1	0.9
Chronic bronchitis/emphysema (father)	0.5	0.6	2.2	1.0	-0.3	1.5	1.1	0.0	0.4	0.5	0.7	-0.7	-0.7	0.3
Impedance of leg (left)	0.5	2.6	9.5	2.2	1.1	-0.4	0.7	3.1	-1.1	0.6	2.8	0.9	0.8	-1.0
Father’s age at death	0.5	0.7	1.8	-1.3	0.4	-1.3	-0.8	-0.6	-0.9	0.3	-0.5	-0.0	0.8	-1.0
Number of children fathered	0.5	0.5	1.9	0.8	0.3	-0.5	1.1	1.1	0.3	1.4	-0.2	-0.3	-0.4	0.2
Emphysema/chronic bronchitis	0.5	0.5	1.7	0.0	0.8	-0.7	0.5	0.4	-0.7	-0.8	-1.3	0.9	0.5	-0.3
Heart disease (mother)	0.5	0.7	2.0	1.3	0.8	0.8	0.4	1.4	-0.1	1.2	-0.6	0.6	0.4	-0.0
Heart disease (siblings)	0.5	0.6	2.7	-0.4	-0.3	0.2	-0.0	-1.7	0.6	0.4	0.8	0.8	-0.1	1.2
Irritable Bowel Disease (IBD)	0.4	1.1	4.0	1.1	1.2	-0.4	-1.1	2.0	0.5	0.8	1.0	-0.1	1.3	0.3
Relative age of first facial hair	0.4	0.8	3.4	-0.4	0.0	0.3	0.1	-1.8	0.3	-0.9	-1.6	0.6	-0.6	0.8
Impedance of leg (right)	0.4	2.1	7.4	1.6	1.1	-0.6	0.5	2.7	-1.2	0.5	2.6	1.0	0.9	-1.0
Fed-up feelings	0.4	0.7	3.0	1.7	0.9	-0.1	0.5	0.4	-0.1	0.6	-0.8	-0.8	1.3	0.0
Relative age voice broke	0.4	0.6	1.8	-0.9	-0.4	-0.9	-0.9	-0.5	-0.7	-1.2	-0.2	1.3	0.6	0.0
Hair/balding pattern: Pattern 2	0.4	0.5	2.4	-0.6	-0.1	0.4	-0.7	-1.1	-0.0	0.7	-0.2	-0.2	-1.5	-0.1
Had menopause	0.4	0.5	3.2	-0.7	-0.2	0.0	0.5	0.2	0.4	-0.2	1.2	0.4	-1.8	0.3
Heart attack	0.4	0.5	1.3	0.8	0.6	1.1	0.3	0.3	0.5	1.0	0.7	-1.1	0.3	0.1
Medication: Ramipril	0.4	0.5	1.7	-0.5	-1.0	1.3	-0.9	-0.4	-0.2	-0.6	0.2	-0.0	-1.1	-0.5
Illnesses of siblings	0.4	0.6	1.9	0.3	0.2	0.2	0.4	1.1	1.4	0.5	0.6	-1.3	0.1	1.0
Number of live births	0.4	0.5	2.9	0.7	-0.4	-0.7	0.4	0.4	-0.8	-0.4	1.7	-0.2	0.2	-0.7
Pulse rate	0.4	0.7	1.6	0.3	-0.9	-1.2	-1.2	0.6	-0.8	-0.6	-0.2	0.5	-1.1	-1.3
Blood clot in the leg (DVT)	0.4	0.5	1.9	0.5	0.7	-1.1	-0.7	1.4	-0.5	-0.0	-0.5	-0.0	0.2	-0.5
Alcohol intake frequency.	0.4	0.8	1.4	1.2	0.3	1.0	0.8	-0.5	1.2	1.0	0.8	-1.0	-0.9	0.9
Number of full sisters	0.4	0.5	1.3	0.8	1.1	1.1	0.9	0.2	-0.0	0.8	0.4	-0.0	0.7	0.2
Leg pain on walking	0.4	0.5	3.5	0.6	-0.0	1.0	0.6	-0.6	0.1	0.0	0.2	0.0	-1.9	-0.4
Illnesses of father: None of the above (group 1)	0.4	0.4	1.5	-0.5	0.9	-1.2	-0.6	0.7	0.2	-0.3	0.9	0.3	0.6	0.5
Commuting to job workplace: Public transport	0.4	0.5	1.9	-0.4	0.2	-0.2	0.6	-0.9	0.7	1.1	0.1	-0.3	1.4	0.6
Alcohol drinker status: Never	0.4	0.5	2.0	-0.1	-1.4	0.6	0.3	-0.5	0.6	-0.2	0.7	-0.2	-1.2	0.8
Age started oral contraceptive pill	0.4	0.5	1.3	-0.5	-0.8	0.7	0.2	0.1	1.1	-0.4	0.0	-0.8	-1.0	0.7
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.2	0.7	0.5	1.1	0.0	0.3	0.5	0.9	0.8	-1.1	0.4	0.2
Townsend deprivation index at recruitment	0.3	0.4	1.1	1.1	0.3	-0.3	-1.0	-0.6	-0.3	0.4	0.3	-0.2	1.0	-0.2
Hair/balding pattern: Pattern 3	0.3	0.5	1.1	-0.8	-0.2	-1.0	-1.1	-0.9	-0.6	-0.2	-0.0	0.4	1.0	-0.3
Exposure to tobacco smoke at home	0.3	0.4	1.2	0.5	-0.0	0.3	0.5	-1.1	0.6	0.0	-0.0	-0.9	-0.1	1.0
Hair/balding pattern: Pattern 4	0.3	0.8	4.0	0.0	0.4	-1.0	2.0	0.9	-0.5	-0.4	-1.0	-0.1	0.2	-1.0
Wheeze or whistling in the chest in last year	0.3	0.6	1.9	0.1	-1.3	0.2	-0.5	-0.9	0.1	0.1	0.3	-1.1	-1.4	-0.4
Mood swings	0.3	0.6	1.4	1.1	0.9	-1.1	0.5	0.2	-0.6	-0.1	-0.4	-0.8	0.1	-1.2
Medication: Aspirin	0.3	0.4	1.7	0.6	0.3	1.3	-0.6	-0.0	0.1	0.7	0.9	-0.8	-0.2	-0.3
Irritability	0.3	0.4	1.9	0.5	0.8	-0.3	-1.4	0.3	-0.3	-0.3	0.2	-0.7	-0.5	-0.9
Pain experienced in last month	0.3	0.6	1.9	0.1	1.1	1.0	0.5	0.2	0.9	0.3	0.6	0.0	0.8	1.4
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	2.0	0.5	0.5	-1.1	-0.7	1.4	-0.4	0.1	-0.3	-0.2	-0.1	-0.6
Diabetes (mother)	0.2	0.2	0.5	0.5	0.3	0.6	0.2	0.3	-0.1	0.7	0.6	-0.5	-0.6	-0.1
Financial difficulties in last 2 years	0.2	0.3	1.4	0.2	0.2	0.1	-0.7	-0.6	-0.5	0.2	-0.5	-0.0	1.2	-0.7
Falls in the last year	0.2	0.2	1.3	1.1	0.6	-0.3	0.1	0.6	0.0	0.4	0.1	0.3	-0.1	-0.3
Number of full brothers	0.2	0.3	0.8	-0.3	0.2	-0.9	-0.7	-0.5	-0.1	-0.1	-0.3	0.5	0.6	0.8
Overall health rating	0.2	0.5	1.8	0.1	-0.1	-0.3	-0.4	-0.2	-0.2	-1.4	-0.7	1.2	-1.1	-0.7
Ulcerative Colitis (UC)	0.1	0.2	0.7	0.5	-0.3	-0.6	-0.9	0.6	0.0	0.5	0.1	0.3	0.3	-0.1
Average weekly spirits intake	0.1	0.1	0.4	-0.5	-0.7	-0.0	-0.0	0.1	-0.5	-0.2	0.1	-0.0	-0.1	-0.7
Hearing difficulty/problems: Yes	0.1	0.2	0.6	0.4	0.0	0.1	-0.7	0.7	-0.3	-0.6	0.3	-0.2	-0.2	-0.4
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Mean Putamen Volume	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Fasting Glucose	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HbA1C	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Lupus	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Neuroticism (2016)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Primary Biliary Cirrhosis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Rheumatoid Arthritis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Eosinophil Count	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Platelet Count	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Red Count	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood White Count	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Heel T-Score	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
BMI	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Height	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Waist Hip Ratio (WHR)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Systolic Blood Pressure	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Smoking Status	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Allergy or Eczema	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Cardiovascular Disease	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hypothyroidism (self reported)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Respiratory disease	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Lung FEV1/FVC ratio	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Lung FVC	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Neuroticism	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Chronotype (morning person)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Tanning	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

TRIM38

Models

Trait associations