Best TWAS P=5.01e-09 · Best GWAS P=2.11e-08 conditioned to 0.0228
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | ZHX2 | 0.21 | 0.20 | lasso | 4 | 0.20 | 6.8e-63 | -5.2 | 5.8 | 5.0e-09 | 0.67 | 0.02 | 0.97 | TRUE |
2 | YFS | Blood | ZHX2 | 0.31 | 0.22 | enet | 30 | 0.25 | 1.1e-82 | -5.2 | -5.3 | 1.3e-07 | -0.60 | 0.02 | 0.97 | FALSE |