Best TWAS P=5.32e-20 · Best GWAS P=3.05e-23 conditioned to 0.00181
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | SLC38A2 | 0.02 | 0.02 | blup | 341 | 0.01 | 5.8e-03 | -9.3 | 8.5 | 1.8e-17 | -0.90 | 0.05 | 0.90 | FALSE |
| 2 | NTR | Blood | SLC38A1 | 0.12 | 0.07 | lasso | 6 | 0.08 | 8.4e-24 | 5.8 | -5.8 | 8.2e-09 | 0.08 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SLC38A2 | 0.10 | 0.06 | blup | 30 | 0.05 | 8.3e-04 | -9.8 | 9.2 | 5.3e-20 | -0.86 | 0.01 | 0.90 | TRUE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | SLC38A2 | 0.06 | 0.01 | blup | 30 | 0.03 | 5.1e-03 | -9.8 | 8.6 | 7.8e-18 | -0.92 | 0.02 | 0.73 | FALSE |