[Hub]/) : Traits : Whole body water mass :

chr14:90,643,934-94,495,324

Best TWAS P=6.39e-11 · Best GWAS P=5.9e-12 conditioned to 0.0858

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta RP11-529H20.6 0.20 0.14 lasso 4 0.18 6.4e-10 -4.5 -5.2 2.5e-07 0.05 0.09 0.88 FALSE
2 GTEx Cells Transformed fibroblasts BTBD7 0.16 0.01 lasso 8 0.04 3.6e-04 -5.5 5.3 1.0e-07 -0.02 0.14 0.84 FALSE
3 GTEx Cells Transformed fibroblasts RPS6KA5 0.08 0.07 lasso 2 0.06 5.3e-05 -6.4 6.5 6.4e-11 -0.89 0.04 0.94 TRUE
4 GTEx Colon Sigmoid RIN3 0.24 0.17 lasso 6 0.11 9.3e-05 6.6 -6.5 9.5e-11 0.03 0.00 0.99 TRUE
5 GTEx Colon Sigmoid RPS6KA5 0.16 0.09 lasso 5 0.08 7.1e-04 -5.2 -5.2 1.8e-07 0.81 0.04 0.89 FALSE
6 GTEx Esophagus Muscularis RIN3 0.17 0.05 lasso 6 0.06 1.6e-04 5.7 -6.0 2.3e-09 0.00 0.04 0.83 FALSE
7 GTEx Prostate RP11-529H20.6 0.28 0.00 lasso 5 0.05 2.5e-02 -4.5 -5.2 2.1e-07 0.07 0.06 0.49 TRUE
8 GTEx Spleen C14orf159 0.30 0.21 lasso 5 0.21 3.6e-06 -5.6 6.5 6.6e-11 -0.81 0.07 0.45 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma RIN3 0.05 0.00 blup 163 0.01 6.0e-02 -2.9 -5.9 3.3e-09 -0.05 0.03 0.07 TRUE
10 The Cancer Genome Atlas Testicular Germ Cell Tumors BTBD7 0.11 0.03 blup 72 0.02 8.0e-02 -5.5 5.5 3.0e-08 -0.01 0.02 0.81 TRUE