TWAS hub - C14orf159

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1000	0.0390	6.2e-03	0.013	0.000	0.016	0.021	0.022	8.0e-03	2.8e-01	3.8e-03	1.1e-03	8.1e-04
2	GTEx	Heart Atrial Appendage	0.1770	0.0680	3.8e-03	0.098	NA	0.029	NA	0.056	3.5e-05	NA	1.8e-02	NA	1.6e-03
3	GTEx	Spleen	0.2950	0.1090	5.8e-03	0.207	NA	0.121	NA	0.213	5.0e-06	NA	5.2e-04	NA	3.6e-06
4	METSIM	Adipose	0.0369	0.0154	2.5e-03	0.005	0.013	0.005	0.011	0.004	5.3e-02	4.0e-03	5.2e-02	6.7e-03	6.4e-02
5	NTR	Blood	0.0970	0.0258	5.3e-06	0.044	0.015	0.061	0.067	0.061	4.9e-14	8.7e-06	4.3e-19	1.4e-20	5.6e-19
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.0721	0.0278	8.8e-05	0.025	0.033	0.019	NA	0.017	7.1e-04	1.2e-04	2.8e-03	NA	4.7e-03
7	TCGA	Brain Lower Grade Glioma	0.0779	0.0310	5.6e-04	0.010	0.011	0.006	NA	0.007	2.5e-02	1.8e-02	6.4e-02	NA	5.0e-02
8	TCGA	Ovarian Serous Cystadenocarcinoma	0.0980	0.0480	2.8e-03	0.011	0.034	0.045	NA	0.042	5.9e-02	2.4e-03	5.4e-04	NA	8.2e-04
9	TCGA	Pheochromocytoma and Paraganglioma	0.1630	0.0710	7.1e-03	0.050	0.041	0.007	NA	0.014	4.8e-03	9.9e-03	1.6e-01	NA	8.7e-02
10	TCGA	Thyroid Carcinoma	0.0650	0.0320	8.1e-03	-0.002	0.014	0.010	NA	0.001	5.9e-01	1.4e-02	3.1e-02	NA	2.7e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Pulse rate, automated reading	5.8	18.6	52.6	1.2	-7.2	6.1	5.3	4.3	-3.2	-0.9	-2.8	-4.6	-2.8
Hip circumference	5.0	21.4	66.8	-0.4	-6.2	8.2	7.0	2.2	-2.8	-3.0	-1.8	-4.8	-3.4
Waist Hip Ratio (WHR)	4.9	22.0	60.1	0.3	6.5	-7.7	-7.8	0.4	1.5	4.0	2.8	3.6	4.4
Alcohol drinker status: Never	4.8	5.8	20.2	1.7	0.7	0.3	0.7	2.2	1.9	4.0	4.5	1.9	2.4
Body mass index (BMI)	3.5	14.8	45.6	-0.3	-4.6	6.7	5.8	1.3	-2.7	-2.6	-2.3	-4.0	-3.1
Impedance of leg (right)	3.4	16.4	62.6	-0.5	5.6	-7.9	-6.5	0.2	2.0	2.2	1.4	2.9	2.9
Impedance of leg (left)	3.4	16.7	61.2	-0.5	5.8	-7.8	-6.7	-0.0	1.7	2.6	1.4	3.0	2.4
Number of full brothers	3.0	3.8	9.9	0.6	-1.9	2.6	1.9	-0.1	3.1	1.8	1.3	2.5	1.6
Impedance of whole body	3.0	15.2	60.1	0.0	5.3	-7.8	-6.3	0.4	1.1	2.7	1.5	2.9	2.1
Number of treatments/medications taken	2.9	5.2	15.4	-0.4	-1.2	1.7	1.3	1.6	-3.1	-1.1	-3.0	-3.9	-2.8
Eye problems/disorders: Diabetes related eye disease	2.9	3.2	9.4	-2.2	2.6	-3.1	-2.8	-1.1	-1.0	-0.1	-0.4	0.4	-0.1
Arm fat mass (right)	2.8	11.6	31.9	-0.6	-4.0	5.7	5.0	1.7	-2.7	-2.5	-2.2	-3.9	-2.7
Seen doctor (GP) for nerves, anxiety, tension or depression	2.8	4.3	13.0	1.9	-2.8	3.6	1.7	0.2	2.3	0.2	2.9	0.1	1.5
Smoking status: Current	2.8	4.4	9.0	0.7	2.7	-3.0	-2.8	-1.4	1.8	0.2	1.6	3.0	1.6
Arm fat mass (left)	2.8	11.4	33.5	-0.2	-4.1	5.8	5.1	1.7	-2.6	-2.3	-2.0	-3.5	-2.8
BMI	2.7	15.4	52.4	-0.1	-4.9	7.2	5.6	1.0	-2.5	-2.5	-2.2	-4.4	-3.1
Weight	2.7	13.1	41.9	-0.6	-4.6	6.5	5.1	1.3	-2.4	-2.9	-1.6	-4.0	-2.7
Coronary Artery Disease (CAD)	2.5	2.9	7.7	0.7	2.8	-1.8	-2.1	0.9	0.7	2.2	0.0	1.7	2.0
Leg fat-free mass (left)	2.5	13.4	47.5	-0.4	-5.2	6.9	5.6	1.2	-1.5	-2.8	-1.0	-3.4	-2.1
Chronic bronchitis/emphysema (mother)	2.5	2.9	11.1	0.1	-2.3	2.9	3.3	-0.5	-0.3	-1.6	-0.8	0.5	-0.7
Leg predicted mass (left)	2.4	13.0	46.6	-0.4	-5.1	6.8	5.5	1.0	-1.4	-2.8	-1.0	-3.4	-2.0
Leg fat-free mass (right)	2.4	13.0	48.0	-0.4	-5.1	6.9	5.5	0.9	-1.4	-2.7	-0.9	-3.2	-2.2
Leg predicted mass (right)	2.4	12.8	47.3	-0.4	-5.0	6.9	5.5	0.9	-1.5	-2.6	-0.9	-3.2	-2.2
Leg fat mass (left)	2.4	9.2	26.0	-0.7	-3.5	5.1	4.5	1.5	-2.2	-2.2	-2.0	-3.4	-2.5
Current tobacco smoking	2.3	3.8	7.8	0.5	2.8	-2.8	-2.7	-1.2	1.6	-0.1	1.5	2.6	1.3
Number of self-reported non-cancer illnesses	2.3	3.9	12.3	1.0	-0.5	-0.4	0.8	1.4	-3.3	-0.8	-2.2	-3.5	-2.7
Basal metabolic rate	2.3	12.6	44.7	-0.7	-4.8	6.7	5.3	0.8	-1.6	-3.0	-0.9	-3.5	-2.2
Taking other prescription medications	2.2	3.5	9.7	-0.0	-1.6	1.1	1.2	0.4	-2.6	-1.8	-2.2	-3.1	-2.2
Whole body fat mass	2.2	9.3	23.5	-0.4	-3.6	4.9	4.6	1.9	-2.5	-2.4	-1.7	-3.4	-2.4
Leg fat mass (right)	2.2	8.7	24.3	-0.6	-3.5	4.9	4.4	1.5	-2.0	-2.2	-1.8	-3.2	-2.3
Arm fat-free mass (left)	2.2	11.2	37.5	-0.7	-4.2	6.1	4.5	0.3	-1.9	-3.0	-1.2	-4.0	-2.4
Trunk fat mass	2.1	9.2	22.2	-0.4	-3.6	4.7	4.4	1.9	-2.6	-2.4	-1.9	-3.3	-2.6
Impedance of arm (right)	2.1	9.9	40.6	-0.0	3.8	-6.4	-5.3	0.9	0.7	2.4	1.2	1.9	2.0
Medication: Ventolin 100micrograms inhaler	2.1	2.7	7.4	-2.6	-1.9	0.7	-0.1	-0.4	-2.0	-1.6	-2.7	-1.1	-0.8
High cholesterol (Self-reported)	2.1	3.7	13.7	1.6	3.6	-3.7	-1.5	-0.2	-1.6	0.0	-0.4	-0.8	-1.2
Arm predicted mass (left)	2.1	10.7	38.9	-0.3	-4.1	6.2	4.6	0.3	-1.5	-2.8	-1.0	-3.8	-2.1
Age at First Birth	2.0	2.8	6.9	-0.3	2.3	-2.2	-2.6	-1.5	1.5	-0.1	1.6	1.5	1.2
Diverticular disease/diverticulitis (self-reported)	2.0	2.3	7.9	-1.4	-1.4	1.0	-0.4	1.1	-2.2	0.1	-1.9	-2.8	-0.8
Impedance of arm (left)	2.0	9.3	36.1	0.4	3.7	-6.0	-4.7	0.9	1.0	2.4	1.6	2.6	1.9
Comparative body size at age 10	2.0	5.6	19.5	-1.3	-3.1	4.4	3.8	0.4	-1.0	-1.1	-1.9	-2.2	-0.6
Suffer from ‘nerves’	2.0	3.2	7.6	2.2	0.9	-1.7	-0.4	1.3	2.1	1.9	2.8	-0.1	2.4
Friendships satisfaction	2.0	2.5	7.4	1.3	1.1	-1.1	-0.5	0.9	1.9	1.5	1.7	1.9	2.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.0	4.2	8.1	1.1	2.2	-2.8	-2.8	-1.7	1.6	-0.9	2.0	2.4	2.0
Whole body water mass	2.0	11.5	42.6	-0.8	-4.6	6.5	5.0	0.5	-1.4	-2.9	-0.8	-3.3	-1.9
Medication: Lisinopril	2.0	2.6	9.9	0.6	0.5	-2.1	-1.8	-0.3	-3.1	-0.3	-1.1	-1.8	-1.8
Type 2 Diabetes (T2D) (2012)	1.9	2.2	10.7	0.7	1.1	-2.9	-3.3	0.6	0.4	-0.4	0.5	0.1	0.9
Heart attack	1.9	2.4	3.8	0.8	1.7	-1.5	-1.5	0.4	1.9	1.8	1.9	1.3	1.9
Arm fat-free mass (right)	1.9	9.6	35.8	-0.8	-4.0	6.0	4.4	0.0	-1.2	-3.0	-0.7	-3.0	-1.9
Arm predicted mass (right)	1.9	9.7	35.1	-0.7	-4.0	5.9	4.4	-0.0	-1.3	-3.0	-1.0	-3.1	-2.1
Whole body fat-free mass	1.9	11.1	41.1	-0.7	-4.6	6.4	5.0	0.4	-1.2	-2.8	-0.7	-3.2	-1.8
Arm fat percentage (left)	1.9	7.5	18.7	-0.0	-3.2	4.3	4.2	1.7	-2.3	-1.7	-1.7	-2.7	-2.5
Heart attack/myocardial infarction (self-reported)	1.9	2.4	3.8	0.6	1.9	-1.6	-1.4	0.4	1.9	1.7	1.9	1.4	1.8
Financial difficulties in last 2 years	1.8	2.4	5.6	1.3	-1.3	2.1	2.2	2.4	0.8	1.3	1.7	-0.1	0.6
Arm fat percentage (right)	1.8	7.0	16.6	-0.2	-3.1	4.1	3.9	1.7	-2.3	-1.5	-1.8	-3.1	-2.3
Miserableness	1.8	3.1	10.9	0.8	-2.0	2.8	3.3	2.0	0.6	1.4	-0.3	-1.3	0.1
Ovarian Cancer	1.7	2.3	4.9	-1.1	1.9	-2.0	-2.2	-1.6	0.8	0.4	1.4	1.6	0.7
Ever unenthusiastic/disinterested for a whole week	1.7	2.0	8.0	0.6	1.1	0.2	1.2	0.3	1.9	1.6	2.8	1.5	0.9
Pulse rate	1.7	2.9	11.4	-0.0	-3.4	2.1	1.1	1.3	-1.3	0.2	-1.9	-1.7	-1.4
Smoking status: Previous	1.7	2.6	6.8	-0.7	-2.6	2.3	2.4	0.7	-0.4	-0.8	-1.9	-1.6	-0.0
Breast Cancer	1.6	3.7	15.2	1.6	1.3	-0.0	0.7	0.2	2.3	3.9	3.1	0.9	1.4
Waist circumference	1.6	5.7	20.4	0.2	-3.0	4.5	3.4	1.9	-1.8	-0.9	-0.6	-2.7	-1.2
Alcohol usually taken with meals	1.6	2.6	8.3	0.5	-2.9	1.3	0.9	-0.5	-1.9	-0.8	-1.4	-2.5	-1.5
Frequency of tenseness / restlessness in last 2 weeks	1.6	2.4	5.2	1.7	-1.3	1.3	-0.0	2.3	0.7	2.2	1.9	-1.6	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	1.6	2.1	8.2	-0.2	-2.3	2.9	1.6	-0.1	1.6	-0.6	1.2	0.2	0.9
Alcohol intake frequency.	1.6	3.8	17.4	-0.8	-0.4	2.1	4.2	2.6	-1.6	-0.7	-0.3	-1.6	-1.6
Loneliness, isolation	1.6	2.2	7.6	1.4	0.4	1.3	2.0	2.0	0.7	2.8	1.0	-0.4	0.8
Lung FVC	1.5	7.5	15.4	0.5	3.0	-3.7	-3.1	-3.0	2.7	0.6	2.5	3.9	2.1
Trunk fat percentage	1.5	5.9	11.5	-0.0	-2.5	3.3	3.4	2.2	-2.6	-1.6	-1.8	-2.8	-2.4
Trunk fat-free mass	1.5	8.6	32.4	-1.1	-4.0	5.7	4.3	0.0	-0.9	-2.6	-0.5	-2.9	-1.4
Happiness	1.5	1.8	5.1	0.5	1.8	-0.8	-0.2	1.8	0.5	2.2	0.9	0.9	1.8
Medication: Lansoprazole	1.5	1.7	9.1	0.4	-3.0	2.1	1.2	0.3	-0.2	-0.5	-0.0	-1.1	-0.7
Trunk predicted mass	1.5	8.5	32.6	-1.1	-4.0	5.7	4.2	-0.1	-0.9	-2.5	-0.5	-2.9	-1.4
Family relationship satisfaction	1.5	1.9	5.6	0.8	1.8	-1.3	-0.7	1.0	1.5	1.7	0.5	0.7	2.4
Osteoporosis (self-reported)	1.5	1.9	5.7	0.6	1.9	-2.1	0.1	2.4	-1.8	-0.0	-0.5	-1.0	-0.5
Wears glasses or contact lenses	1.5	1.7	4.1	0.2	-1.4	0.2	1.1	-0.3	-2.0	-1.2	-1.2	-1.9	-1.8
Tinnitus: Yes, now most or all of the time	1.5	1.8	6.0	-1.5	-0.7	1.0	1.3	2.5	-1.0	-1.6	-1.0	-0.6	-1.2
Respiratory disease	1.4	3.0	5.7	-0.3	-2.4	2.3	2.1	0.8	-1.5	-1.9	-2.0	-1.4	-1.4
Body fat percentage	1.4	5.5	12.3	-0.0	-2.5	3.3	3.5	2.1	-2.3	-1.5	-1.6	-2.7	-2.1
Number of children fathered	1.4	1.5	5.3	0.2	-2.3	1.5	2.0	0.9	0.7	0.3	1.0	-0.0	1.1
Long-standing illness, disability or infirmity	1.4	2.1	6.9	0.4	-0.9	1.0	0.7	2.6	-2.0	0.9	-0.1	-2.5	-0.8
Medication: Gliclazide	1.4	1.6	5.5	0.6	0.3	-1.0	-1.1	2.4	-1.6	0.8	-0.9	-1.7	-1.0
Leg fat percentage (left)	1.4	5.1	12.0	-0.3	-2.2	3.5	3.3	1.5	-2.0	-1.4	-1.8	-2.5	-2.3
Number of operations (self-reported)	1.4	2.0	6.3	1.7	-2.1	2.5	1.3	1.3	-1.1	0.0	0.4	-1.1	-0.4
Basal cell carcinoma (self-reported)	1.4	1.7	5.2	2.3	-0.8	0.6	1.7	0.2	1.0	1.5	0.1	0.8	1.9
Major Depression (MDD)	1.3	1.6	5.6	0.3	-0.8	2.4	1.9	-0.5	-0.2	-2.1	0.0	-0.3	-1.2
Severe depression (siblings)	1.3	1.5	5.3	0.8	-2.0	2.3	1.7	-0.3	0.4	0.9	-0.4	-0.3	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.7	5.6	0.4	0.1	1.4	1.4	2.4	0.8	2.1	1.2	-0.5	1.0
Forced expiratory volume in 1-second (FEV1)	1.3	4.4	9.8	-0.0	2.7	-2.8	-3.1	-1.4	1.8	0.7	2.7	2.1	1.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.3	8.3	-0.8	2.9	-2.6	-2.9	-1.6	1.9	0.5	2.3	2.3	1.4
Headache pain in last month	1.3	2.3	4.7	0.6	-2.1	1.6	1.3	1.2	-1.2	-2.1	-2.2	-1.0	-1.1
Emphysema/chronic bronchitis	1.3	1.4	5.0	0.5	-0.9	0.8	1.0	-0.3	-1.2	-1.0	-0.9	-1.8	-2.2
Medication for cholesterol	1.3	2.0	6.9	-1.5	-2.6	2.6	1.2	1.2	0.4	-0.0	-0.6	-0.1	0.8
Mineral and other dietary supplements	1.3	1.7	6.1	0.5	2.5	-2.2	-1.8	-0.6	-0.0	0.4	1.1	1.0	0.2
Supplements: Fish oil (including cod liver oil)	1.3	1.7	7.0	-0.8	-2.2	2.6	2.1	0.1	0.4	-0.0	-0.5	-0.7	-0.2
Ever depressed for a whole week	1.3	1.6	7.4	0.3	0.6	0.7	0.2	0.6	1.7	0.6	2.7	1.4	1.6
Pain experienced in last month	1.3	2.2	6.3	1.1	1.5	-2.5	-1.7	-0.2	1.1	1.2	1.7	1.2	1.5
Alzheimer’s Disease (in father)	1.2	1.3	3.5	0.8	-0.3	0.7	1.1	-0.4	-1.4	-0.1	-1.9	-1.6	-1.5
Medication: Levothyroxine sodium	1.2	2.0	5.3	1.0	0.7	-0.7	1.3	2.3	1.5	1.9	0.8	1.2	1.9
Had other major operations	1.2	1.5	5.1	-0.2	-0.3	1.1	0.4	-0.5	-1.8	-1.8	-1.1	-0.8	-2.2
Leg fat percentage (right)	1.2	4.4	9.9	-0.2	-2.2	3.2	3.1	1.5	-1.7	-1.5	-1.6	-2.3	-1.9
Mean time to correctly identify matches	1.2	2.2	7.2	1.0	1.9	-2.7	-0.4	-1.3	1.7	0.7	0.6	1.8	1.2
Asthma (self-reported)	1.2	2.3	10.4	-0.5	-3.2	2.2	2.0	0.8	-0.7	-0.7	-1.3	-0.9	-0.0
Medication: Atorvastatin	1.2	1.5	6.0	1.0	2.4	-1.6	-2.0	-0.7	0.0	-0.4	0.8	0.1	-0.6
Cholesterol lowering medication	1.2	1.7	4.8	2.2	2.0	-1.8	-1.6	-0.8	-0.9	0.1	0.1	0.3	-0.9
Reaction Time	1.1	2.0	5.2	1.0	1.2	-2.0	-0.8	-1.2	2.3	0.7	0.9	1.7	1.4
Systolic Blood Pressure	1.1	5.5	17.0	-0.4	4.1	-3.9	-3.9	-2.0	-0.6	1.3	-0.8	0.3	0.1
Cardiovascular Disease	1.1	3.7	11.6	1.3	3.2	-3.4	-2.6	-1.3	-0.6	1.3	-0.5	-1.2	-1.1
Diabetes (mother)	1.1	1.4	3.9	1.2	0.7	-0.7	-0.8	-0.7	1.0	1.2	2.0	0.9	1.7
Forced vital capacity (FVC)	1.1	4.3	9.4	-0.4	2.2	-2.3	-2.8	-1.6	2.2	0.8	3.1	2.4	1.4
Mouth/teeth dental problems: Dentures	1.1	1.9	4.5	-0.7	0.1	-0.2	-0.7	1.0	-2.0	-1.3	-1.8	-1.9	-2.1
Asthma	1.1	2.3	10.8	-0.1	-3.3	2.3	1.8	0.6	-0.6	-0.4	-1.2	-0.8	-0.0
Medication: Cholesterol lowering	1.1	1.7	4.7	0.9	1.8	-2.2	-1.6	1.6	-0.6	1.6	0.1	-0.8	-0.1
Pulse wave reflection index	1.1	1.4	5.7	-0.7	2.4	-1.9	-1.0	0.1	0.1	1.0	1.1	0.8	0.3
Blood clot in the leg (DVT)	1.1	1.4	4.5	-0.3	-0.4	1.6	2.1	0.8	1.2	0.7	0.7	0.5	1.9
Eye problems/disorders: Glaucoma	1.1	1.3	3.1	-0.2	1.2	-1.2	-1.6	0.8	-1.6	1.8	0.1	-1.0	-0.2
Medication: Omeprazole (e.g. Zanprol)	1.1	1.4	4.1	-0.1	0.4	-0.8	1.0	1.1	-1.5	-0.4	-2.0	-1.5	-1.3
Depression (Nagel 2018)	1.0	1.4	4.6	-0.3	-0.1	1.0	1.3	1.4	1.1	2.1	1.5	-0.3	1.1
Average weekly spirits intake	1.0	1.2	3.6	0.2	-1.1	0.9	0.8	-0.3	-1.1	-1.0	-1.5	-1.2	-1.9
Frequency of depressed mood in last 2 weeks	1.0	1.4	3.0	0.8	-0.4	1.2	0.7	1.0	1.6	1.7	1.7	0.2	1.2
Average weekly fortified wine intake	1.0	1.1	2.2	-1.5	0.8	-0.7	-1.3	-1.0	1.3	0.8	0.3	1.2	1.3
Supplements: Glucosamine	1.0	1.3	4.6	-0.9	-2.1	1.2	1.0	-0.2	-1.1	-0.5	-0.7	-1.2	-1.3
Medication: Atenolol	1.0	1.3	3.2	0.7	0.8	-0.8	-1.5	0.1	1.8	0.7	1.2	0.4	1.8
Nervous feelings	1.0	1.8	6.0	1.2	0.4	-0.9	-0.4	2.0	1.4	2.4	0.7	-0.3	1.7
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.3	17.2	-0.6	-0.1	1.1	-0.9	-4.2	0.6	0.5	1.7	0.3	-0.5
Falls in the last year	1.0	1.3	5.4	0.9	0.8	0.9	2.3	1.5	-0.1	-0.2	1.6	0.5	-0.7
Hypothyroidism/myxoedema (self-reported)	1.0	2.0	5.6	0.6	1.3	-1.0	0.7	1.3	1.5	2.2	0.5	1.2	2.4
Forced vital capacity (FVC), Best measure	1.0	3.6	6.0	-1.1	2.2	-2.2	-2.5	-1.5	2.0	0.6	2.3	2.2	1.4
Age at first live birth	1.0	1.8	4.4	0.2	0.9	-1.7	-2.1	-0.9	1.2	-0.7	0.2	1.7	2.1
Pulse wave peak to peak time	1.0	1.2	2.5	0.4	0.8	-0.7	-1.5	-1.2	1.4	0.1	1.0	1.6	1.0
Average weekly red wine intake	1.0	1.4	3.3	0.4	-0.4	-1.0	-1.8	-1.8	-1.6	-1.4	-0.2	-1.0	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.0	4.5	-1.1	-2.1	1.3	1.2	0.6	-0.5	0.2	-0.4	-0.6	-0.5
Osteoarthritis (self-reported)	1.0	1.2	4.4	0.5	0.1	0.3	0.3	-0.5	-1.6	-0.4	-1.2	-1.8	-2.1
Medication: Bendroflumethiazide	1.0	1.5	3.5	-0.6	1.1	-0.8	-0.2	-0.9	-1.8	-1.5	-0.6	-1.7	-1.9
Medication: Paracetamol	1.0	1.5	5.2	-1.3	-2.3	1.5	1.5	0.7	-0.2	0.5	0.4	-1.5	-0.4
Myopia	1.0	1.4	3.4	1.5	-0.2	-0.6	-1.2	-1.2	1.9	1.0	0.4	0.9	1.8
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	4.2	-0.1	-0.4	1.5	1.7	0.6	1.3	0.6	0.9	0.5	2.1
Body Mass Index (BMI) (2010)	0.9	1.3	4.8	-0.1	-0.9	2.2	1.7	-0.5	-0.5	0.4	-1.3	-0.2	-1.2
Crohns Disease (2012)	0.9	1.5	6.2	0.6	0.4	0.9	0.5	-0.2	2.5	-0.0	1.8	1.8	0.5
Lupus	0.9	1.3	5.6	-0.1	1.0	-2.4	-1.9	1.4	0.5	0.4	-0.0	0.6	0.6
Type 2 Diabetes (T2D) (2018)	0.9	1.6	3.5	1.7	1.3	-1.3	-1.8	1.9	0.1	1.3	0.1	-0.4	1.1
Supplements: Zinc	0.9	1.0	3.0	-0.1	0.3	1.2	1.5	0.1	-0.8	-0.8	-1.0	-1.0	-1.7
Maternal smoking around birth	0.9	1.3	6.1	-1.0	-1.4	0.6	0.7	0.9	-1.1	-0.0	-2.5	-0.9	-0.5
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	3.5	0.7	-1.4	1.4	0.6	0.1	-1.2	0.1	-1.4	-1.9	0.0
Medication: Simvastatin	0.9	1.3	2.7	1.6	1.5	-1.6	-1.2	1.1	-0.6	1.3	0.2	-0.2	0.3
Father’s age at death	0.9	1.3	6.9	-1.3	-0.4	-0.8	-0.6	-0.9	0.2	-2.6	-1.5	-0.0	0.3
Hair/balding pattern: Pattern 3	0.9	1.3	4.6	1.0	2.1	-1.1	-1.4	-0.9	0.9	1.6	0.3	0.4	0.3
Pulse wave Arterial Stiffness index	0.9	1.1	2.4	-0.5	-0.8	0.8	1.3	1.3	-1.4	-0.2	-0.9	-1.5	-0.9
Hair/balding pattern: Pattern 4	0.9	2.1	6.4	-1.5	-2.5	1.2	0.9	1.1	-1.6	0.0	-0.7	-2.1	-1.3
Medication: Paracetamol	0.9	1.5	5.8	-0.6	-2.4	1.9	1.6	0.3	-0.1	0.5	0.5	-1.1	-1.0
Glaucoma (self-reported)	0.9	1.0	2.3	0.2	1.5	-0.7	-1.4	0.3	-1.1	1.4	1.1	-0.8	0.4
Migraine (self-reported)	0.9	1.1	4.0	0.3	-1.0	2.0	1.8	1.2	-0.5	0.4	0.2	-1.1	-0.4
Overall health rating	0.9	2.0	5.5	0.4	-0.6	1.7	2.3	2.1	-1.4	0.3	-1.2	-1.5	-0.7
Medication: Aspirin	0.9	1.2	7.1	1.6	2.7	-1.1	-0.5	-1.0	-0.0	-0.3	0.1	-0.0	0.0
Irritability	0.9	1.5	3.2	-0.1	1.6	-1.4	-0.4	1.7	-0.6	1.8	-0.9	-1.7	0.5
Fractured/broken bones in last 5 years	0.9	1.1	4.1	1.4	0.4	0.1	0.8	1.7	1.1	0.2	0.3	2.0	0.6
Schizophrenia vs Biploar Disorder	0.8	1.1	3.8	-1.4	0.6	-2.0	0.3	0.7	0.6	1.4	0.0	1.0	0.9
Worry (Nagel 2018)	0.8	1.8	6.1	1.2	0.4	-1.1	0.3	1.4	1.4	2.5	0.8	-1.2	1.5
Mean Putamen Volume	0.8	1.0	2.7	-1.2	1.5	-1.6	-0.2	-0.4	-1.3	0.9	0.4	-0.5	-0.3
Hand grip strength (left)	0.8	2.0	6.4	0.1	-1.4	1.0	-1.0	-1.4	2.5	-0.0	1.8	1.5	1.5
Qualifications: CSEs or equivalent	0.8	1.1	4.3	0.8	1.3	-1.6	-2.1	-0.2	0.6	-0.1	-0.1	-1.2	-0.2
Stomach or abdominal pain in last month	0.8	1.0	3.2	0.5	-0.8	1.8	1.0	1.5	0.6	1.2	-0.2	0.2	0.8
High blood pressure (mother)	0.8	1.1	4.2	-0.4	1.4	-2.0	-0.7	-0.7	-1.2	0.8	-0.2	-0.9	-0.5
Had menopause	0.8	1.0	3.2	0.8	0.9	-1.8	-1.1	-0.5	-0.9	-1.2	-0.7	0.1	-1.1
Number of live births	0.8	1.2	3.3	1.8	-1.1	1.8	1.2	0.3	-0.6	-0.9	-0.3	-1.0	-0.4
Noisy workplace	0.8	1.0	5.2	-0.0	-0.2	0.1	1.5	-0.5	-0.6	-0.6	-2.3	-1.2	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	4.3	2.1	-0.6	0.9	-0.6	-0.7	0.6	-0.3	-1.0	0.6	0.9
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	4.5	-0.2	0.9	0.3	0.4	-0.6	-1.2	-0.3	-2.1	-0.6	-1.4
Exposure to tobacco smoke at home	0.8	0.9	2.4	-1.6	-0.3	1.4	0.0	1.0	0.5	-0.1	1.0	0.9	1.2
Eye problems/disorders: None of the above	0.8	1.0	2.5	0.6	-1.2	1.2	0.2	-1.2	1.6	-1.0	0.6	0.9	0.6
Medication for pain relief, constipation, heartburn	0.8	1.4	3.0	0.5	0.4	-1.4	-1.7	-0.5	0.9	0.3	1.6	1.5	1.6
Medication: Omeprazole	0.8	1.0	2.7	0.1	0.7	-0.4	0.7	1.0	-1.4	-0.0	-1.6	-1.2	-1.3
Illnesses of father: Heart disease	0.8	1.0	4.5	0.6	1.8	-1.2	-0.7	0.4	-0.5	2.1	0.1	0.5	-0.0
Eye problems/disorders: Cataract	0.8	0.9	3.5	0.7	-0.8	1.0	1.9	1.1	-0.7	0.3	-0.9	-0.9	-0.4
Back pain experienced in last month	0.8	1.2	3.0	-0.9	-0.2	0.9	1.3	-0.4	-1.4	-0.4	-0.4	-1.7	-1.7
Ever taken oral contraceptive pill	0.8	0.9	5.6	-0.0	-0.2	1.2	0.8	-0.2	1.1	0.3	2.4	0.1	-0.0
Pain type(s) experienced in last month: Hip pain	0.8	1.0	3.0	-1.5	0.7	-0.5	-0.0	0.9	-1.1	1.7	-0.4	-1.2	0.0
Age started oral contraceptive pill	0.8	1.1	2.8	-0.9	1.4	-1.7	-0.8	-1.3	-0.4	-0.3	0.3	1.2	-0.9
Alzheimer’s Disease (in mother)	0.7	0.8	2.9	-0.2	-0.9	1.7	0.8	0.5	0.8	1.3	0.8	-0.4	0.6
Verbal and Numeric Reasoning (VNR)	0.7	1.7	4.3	1.1	-2.1	0.8	-0.8	0.8	1.2	1.5	1.6	0.4	1.7
HDL Cholesterol	0.7	1.2	3.2	-1.3	0.8	-0.4	-0.5	-0.5	-1.1	-1.8	-1.1	-1.5	-1.3
Fed-up feelings	0.7	1.3	4.7	0.4	0.8	0.8	1.8	2.2	0.9	1.5	0.4	0.3	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.7	11.3	-0.7	-0.4	1.3	-0.5	-3.4	0.5	0.5	1.5	-0.0	-0.3
Past tobacco smoking	0.7	1.3	3.9	0.5	2.0	-1.3	-0.9	0.2	0.0	0.9	1.9	1.0	-0.5
Hair/balding pattern: Pattern 2	0.7	0.9	4.0	-1.1	0.5	-0.4	0.0	-1.6	-0.0	-2.0	-0.6	0.7	0.4
Mouth/teeth dental problems	0.7	1.1	2.9	0.6	-0.2	0.0	-0.2	0.0	1.5	1.6	1.7	1.2	1.0
Allergy	0.7	1.5	5.3	-0.0	2.0	-2.3	-2.3	0.0	0.1	0.6	-0.2	0.1	-0.6
Fluid intelligence score	0.7	1.5	3.0	0.8	-1.3	0.9	-1.1	1.0	1.3	1.3	1.7	0.3	1.7
Time employed in main current job	0.7	0.8	4.4	-0.1	0.6	-1.2	-2.1	-0.7	-0.1	-0.5	-0.6	-0.0	0.4
Prospective memory result	0.7	0.9	2.2	-0.6	1.3	-1.3	0.0	-1.5	0.4	0.8	0.2	1.4	0.2
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	3.1	-0.1	-0.8	1.8	1.6	-0.9	1.1	-0.1	1.1	1.5	0.5
Gout (self-reported)	0.7	1.0	2.7	-0.9	1.6	-1.6	-1.2	-0.8	0.7	1.0	0.1	0.1	0.1
Medication: Amlodipine	0.7	0.9	3.0	0.2	0.9	-1.6	-1.7	-1.0	-0.7	0.1	-0.2	-0.5	-1.0
Birth weight	0.7	1.5	4.5	0.9	0.5	-0.9	0.2	1.6	0.3	2.1	1.4	-0.3	1.9
Health satisfaction	0.7	0.9	3.7	1.9	-0.1	0.8	0.1	1.4	-1.2	-0.3	-0.2	-1.1	0.2
Angina (self-reported)	0.7	0.9	2.7	1.6	1.4	-1.5	-0.8	-0.0	0.8	0.3	-0.0	1.0	0.2
Heart disease (mother)	0.7	0.9	2.5	1.6	-0.6	0.3	-1.0	0.2	-1.4	-0.2	-0.1	-1.4	-0.9
Chest pain or discomfort	0.7	1.0	3.1	-0.4	-1.3	1.2	1.8	0.1	1.1	0.0	0.5	1.4	0.8
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	2.1	-1.0	0.3	-0.4	1.0	0.8	-1.1	-1.0	-1.0	-0.0	-1.4
Illnesses of siblings: Diabetes	0.7	0.9	2.5	-1.3	-0.2	0.3	0.2	-0.2	-1.2	-0.7	-1.0	-1.4	-1.6
Handedness (chirality/laterality): Left-handed	0.7	0.8	2.7	-1.0	-1.3	-0.2	0.7	0.4	-0.6	0.9	-1.7	-0.8	-0.5
Mood swings	0.7	1.3	5.5	1.4	-0.8	0.5	1.0	1.4	-0.7	0.6	-0.9	-2.3	-0.3
Commuting to job workplace: Walk	0.7	0.8	3.0	0.9	0.2	-0.6	-1.7	-1.6	0.1	-0.0	0.5	0.3	-0.8
Unable to work because of sickness or disability	0.7	0.9	2.3	-0.7	-1.0	1.5	1.2	0.3	-0.5	-0.8	-1.5	-0.9	-0.5
Heart disease (siblings)	0.7	0.8	3.3	0.0	-0.5	-0.6	0.0	-0.1	-1.5	-0.2	-1.2	-1.8	-0.4
Depressed Affect (Nagel 2018)	0.6	1.3	5.5	-0.2	-0.6	0.8	2.3	1.4	0.3	1.3	-0.9	-1.3	-0.2
Neuroticism (Nagel 2018)	0.6	1.3	3.8	0.8	-0.5	0.1	1.2	1.8	0.7	1.9	-0.2	-1.7	0.9
Schizophrenia (2018)	0.6	1.3	5.9	-2.4	1.1	-0.7	-0.7	-1.0	0.3	-0.5	1.8	0.3	0.1
Alzheimer’s Disease (including proxy)	0.6	0.9	2.2	0.7	-0.5	1.5	1.4	0.6	0.3	1.4	0.0	-1.1	0.3
Prostate Cancer	0.6	0.8	2.9	-1.7	0.4	-0.6	-0.2	-0.5	0.4	1.1	-0.3	1.6	1.0
Primary Biliary Cirrhosis	0.6	0.9	3.8	-0.5	-0.8	-1.0	-0.6	0.9	0.3	1.2	0.7	-0.3	2.0
Hypothyroidism (self reported)	0.6	1.4	4.6	0.2	0.7	-0.4	1.0	2.1	1.0	1.6	1.1	0.4	1.8
Relative age of first facial hair	0.6	1.2	4.8	0.8	-0.9	-1.3	-0.8	0.7	1.3	0.7	0.2	0.4	2.2
Angina	0.6	0.8	2.6	1.6	1.4	-1.3	-0.5	0.1	0.8	0.5	0.2	1.0	0.3
Diabetes (father)	0.6	0.7	2.6	0.2	0.2	0.9	0.5	1.6	-0.2	1.5	-0.6	-1.0	0.4
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	2.6	1.1	-0.4	-0.1	-0.1	-0.4	-1.2	-0.7	-1.6	-0.6	-0.5
Multivitamins +/- minerals	0.6	0.7	2.6	-0.0	0.6	-0.2	0.2	0.9	1.1	1.6	0.9	0.7	0.9
Pain all over the body in last month	0.6	0.7	2.7	0.1	0.0	1.3	1.7	1.3	0.2	-0.6	0.1	-0.1	-0.6
Medication: Ramipril	0.6	0.7	2.5	1.1	0.2	-0.8	-1.2	0.2	-0.6	-0.9	-0.4	-1.6	-0.3
Neuroticism score	0.6	1.3	7.0	0.7	-0.2	0.0	0.5	1.7	1.2	2.6	0.2	-0.5	1.0
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	3.1	0.6	-1.3	1.8	1.3	1.2	0.4	0.7	0.7	-0.9	0.4
Ever highly irritable/argumentative for 2 days	0.6	0.7	2.3	0.4	1.5	-1.0	-0.8	-1.1	0.6	0.3	0.4	0.5	0.7
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	2.5	0.1	-1.0	0.5	0.6	0.1	1.2	0.3	-0.5	1.2	1.6
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.8	2.0	-1.4	0.8	-1.4	-0.5	-1.1	0.1	0.9	0.6	0.1	0.6
Neck or shoulder pain in last month	0.6	0.9	3.4	-0.7	-1.0	0.6	1.2	-1.8	-0.2	-0.6	-0.6	-0.2	-1.2
Medication: Blood pressure	0.6	1.0	4.0	-0.1	0.3	-1.1	-0.7	0.9	-1.1	-0.8	-2.0	-1.1	-0.3
Medication: Ibuprofen	0.6	0.7	3.3	-0.6	0.8	0.4	0.5	0.1	-1.0	0.4	-1.8	-1.0	-0.8
Age at last live birth	0.6	0.9	3.6	-0.0	0.5	-0.4	-0.8	-1.9	0.4	-0.4	-1.4	0.7	1.1
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.9	-0.0	0.1	0.3	1.7	0.8	-0.2	-0.7	-1.7	-0.5	0.1
Medication: Aspirin	0.6	0.8	4.3	1.2	2.1	-0.7	-0.2	-1.2	0.1	-0.1	0.1	-0.1	-0.2
Supplements: Vitamin C	0.6	0.7	2.0	0.1	0.2	-0.2	0.9	-0.1	-0.8	-0.8	-1.4	-0.9	-1.3
Qualifications: nursing, teaching	0.6	0.9	3.6	0.5	-0.2	-1.2	-1.9	-1.6	-0.6	0.6	-0.8	-0.5	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.7	-1.3	-1.0	0.7	0.6	1.3	-0.3	0.9	-1.1	0.1	0.0
Medication: Blood pressure	0.6	1.1	2.9	0.6	1.7	-1.5	-1.3	-0.4	-1.1	0.3	0.3	-0.9	-1.3
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.7	-0.3	-1.1	-1.0	-0.4	1.2	-1.3	0.3	-1.0	-0.5	0.2
Supplements: Calcium	0.6	0.7	2.5	1.1	-0.8	0.2	1.6	0.7	0.6	-0.7	-0.5	0.1	0.8
Bipolar Disorder (2018)	0.5	0.7	1.8	-0.3	-0.0	0.6	0.2	-1.3	-1.2	-1.2	-0.4	-0.3	-1.3
Bipolar Disorder or Schizophrenia	0.5	1.1	4.3	-2.1	0.8	-0.2	-0.4	-1.6	-0.5	-1.2	1.2	0.1	-0.7
Fasting Glucose	0.5	0.6	1.7	-1.3	-0.2	-0.1	1.2	0.8	-0.6	-0.3	-1.0	0.0	-1.1
HbA1C	0.5	0.6	3.0	-0.4	0.5	0.2	0.4	-0.2	0.2	1.7	-0.6	0.6	1.2
Triglycerides	0.5	0.8	2.7	-0.8	-1.6	1.1	1.3	0.4	-0.5	-0.7	-0.1	-0.1	-0.8
Smoking Status	0.5	1.2	3.2	-0.2	0.6	-0.9	-1.2	-1.2	1.5	-0.7	-0.1	1.8	1.3
Chronotype (morning person)	0.5	1.1	3.7	-0.5	1.9	-1.3	-1.7	-0.4	0.0	1.3	0.3	0.0	-0.5
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	2.4	0.4	-0.3	0.1	0.4	0.8	-1.5	1.0	-0.2	-1.3	-0.7
Medication for hormone replacement therapy	0.5	0.6	3.1	0.2	0.7	-1.1	-0.2	-0.7	0.8	0.1	1.8	0.2	0.5
Medication: Co-codamol	0.5	0.6	2.5	0.2	-0.9	1.2	1.6	0.8	0.1	0.3	0.2	-0.1	0.3
Medication: Metformin	0.5	0.7	1.5	0.8	0.8	-1.2	-0.6	0.9	-1.1	0.5	-1.2	-0.9	0.0
Pack years adult smoking proportion	0.5	0.8	2.3	1.1	0.1	0.1	-1.2	-0.3	1.5	1.2	0.7	0.3	1.2
Hand grip strength (right)	0.5	1.5	4.6	0.4	-1.4	1.0	-0.8	-1.1	2.2	-0.5	1.4	1.4	1.1
Relative age voice broke	0.5	0.8	1.6	-0.8	0.3	-1.2	0.6	-0.8	1.1	0.1	-1.1	0.9	1.2
High blood pressure	0.5	1.3	3.6	0.4	1.3	-1.9	-1.4	-0.0	-0.8	1.8	-0.5	-1.2	-0.6
Depression (self-reported)	0.5	0.6	3.1	-0.0	0.3	-0.1	0.8	0.3	-0.5	-1.8	0.4	-0.2	-1.3
Lung cancer (father)	0.5	0.6	1.7	0.9	-0.4	0.9	-0.1	-0.6	0.6	-1.3	-0.9	0.7	-0.0
Loud music exposure frequency	0.5	0.6	1.9	1.4	-0.0	0.4	1.3	0.5	-0.5	-0.3	-0.7	-0.4	-0.8
Worry too long after embarrassment	0.5	0.8	2.1	1.4	-1.4	1.0	0.4	0.8	0.2	0.3	-0.1	-0.5	1.2
Number of full sisters	0.5	0.6	1.5	0.6	-0.9	1.1	-0.0	-1.2	0.4	0.1	1.1	0.6	-0.3
Illnesses of father: None of the above (group 1)	0.5	0.6	3.1	0.6	-1.8	0.6	0.1	0.0	0.7	-0.9	1.0	-0.5	0.3
Hearing aid user	0.5	0.6	2.1	-1.1	0.6	0.2	1.5	-0.4	0.6	-0.5	-0.6	0.9	-0.1
Mother’s age at death	0.5	0.6	1.5	-0.7	-1.1	0.7	0.4	-0.5	-0.5	-1.2	-1.2	0.3	-0.0
Financial situation satisfaction	0.5	0.6	1.8	0.8	0.2	-0.8	-1.3	0.9	-0.2	0.7	-0.1	0.7	0.7
Commuting to job workplace: Public transport	0.5	0.6	2.3	-1.1	-0.9	0.0	-1.1	-1.5	0.1	0.2	0.0	0.5	0.1
Average weekly beer plus cider intake	0.5	0.8	2.1	-0.1	1.0	-0.5	-1.0	-0.4	0.6	0.8	1.4	1.4	0.6
Risk taking	0.5	0.7	2.7	-0.1	-1.2	-0.0	-0.8	-0.9	0.8	-0.1	0.7	-0.1	1.6
Vascular/heart problems diagnosed by doctor	0.5	1.5	4.2	-0.8	-1.6	2.0	1.4	0.1	0.5	-2.0	0.2	0.8	0.4
Crohns Disease (2017)	0.4	0.9	2.7	0.9	0.7	1.1	-1.0	-0.5	1.6	0.3	1.0	1.1	0.4
Irritable Bowel Disease (IBD)	0.4	1.0	3.9	-0.3	0.1	1.0	-1.2	-0.3	2.0	0.2	0.7	1.5	1.0
Ulcerative Colitis (UC)	0.4	0.8	2.2	-1.2	-0.5	0.5	-0.9	0.1	1.5	0.2	0.3	1.2	1.1
Blood Red Count	0.4	3.8	15.2	-2.2	2.8	-3.9	-1.1	-0.2	-1.9	-0.9	-1.8	-0.5	-0.9
Heel T-Score	0.4	3.6	13.0	0.7	-0.2	1.0	-0.9	-3.6	2.0	1.8	3.2	1.0	1.3
Neuroticism	0.4	0.9	3.8	0.0	-0.7	0.2	0.6	1.0	0.8	2.0	0.1	-1.2	0.9
Ever used hormone-replacement therapy (HRT)	0.4	0.4	1.5	0.4	-0.7	-0.3	-0.2	1.2	-0.1	0.1	1.0	-1.0	0.5
Ever had hysterectomy (womb removed)	0.4	0.5	2.1	-1.4	0.8	-0.1	-0.1	-0.4	0.0	-0.7	0.6	0.1	-0.9
Systolic blood pressure, automated reading	0.4	1.0	4.0	0.6	2.0	-1.3	-0.7	-0.6	-0.9	1.4	-0.5	-0.4	-0.5
Vitamin and mineral supplements	0.4	0.6	1.9	-0.8	1.0	-1.0	-1.4	-0.0	-0.4	-0.8	-0.0	0.1	0.4
Illnesses of siblings	0.4	0.5	2.4	1.6	-1.1	0.7	-0.1	-0.3	0.6	-0.2	0.6	0.1	0.6
Qualifications: A levels/AS levels or equivalent	0.4	0.9	2.7	0.3	-0.5	0.6	-0.3	-1.3	-1.2	-0.5	-1.2	-1.6	-1.0
Birth weight of first child	0.4	0.8	2.3	-1.0	-0.3	0.8	0.0	-1.2	-1.0	-0.1	-1.0	-1.5	-0.5
Peak expiratory flow (PEF)	0.4	0.9	2.8	0.8	-0.1	-0.3	-1.2	0.3	1.0	1.0	1.7	0.4	1.4
Exposure to tobacco smoke outside home	0.4	0.5	1.3	-0.9	1.2	-0.7	-0.3	0.2	0.4	1.0	0.0	0.9	-0.0
Shortness of breath walking on level ground	0.4	0.5	1.8	0.7	-0.6	0.4	0.9	0.1	0.4	-1.3	-0.4	0.9	0.7
Qualifications: College or University degree	0.4	1.1	4.8	-0.8	-0.4	-0.8	-2.2	-1.8	0.1	-0.3	0.5	0.4	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.7	0.8	-1.3	0.3	0.6	1.3	-0.3	-0.0	-0.0	-0.7	0.4
Had major operations	0.4	0.4	1.2	0.6	0.3	1.1	-0.4	0.1	0.3	0.9	0.4	0.6	1.0
Hypertension (Self-reported)	0.4	1.2	2.8	0.8	1.0	-1.4	-1.1	0.5	-1.1	1.7	-0.5	-1.4	-0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	1.0	0.6	0.9	-0.5	-0.2	1.0	-0.3	-0.9	-0.8	-0.5	0.4
Diabetes diagnosed by doctor	0.4	0.6	1.6	0.3	1.2	-0.8	-0.8	1.3	-0.9	0.6	-0.5	-0.8	-0.1
Guilty feelings	0.4	0.6	2.3	0.3	-0.6	0.8	0.3	0.8	1.0	0.9	-0.1	0.6	1.5
Ever smoked	0.4	0.8	2.8	-0.4	-0.7	-0.1	-0.7	-1.0	0.7	-1.3	-1.7	-0.1	0.7
Alcohol drinker status: Previous	0.4	0.5	1.6	-0.2	0.2	0.9	0.6	0.3	-1.3	-0.6	0.2	-1.1	-0.6
Pack years of smoking	0.4	0.6	1.6	1.1	0.2	0.0	-1.1	-0.3	1.3	0.9	0.5	0.2	0.7
Intelligence (Savage-Jansen 2018)	0.3	1.1	3.9	0.7	-2.0	0.6	0.2	1.1	1.2	0.5	1.4	0.7	0.7
Bipolar Disorder (2011)	0.3	0.3	1.5	1.0	0.4	-0.1	-0.2	-1.2	0.0	0.0	0.0	0.0	0.0
Rheumatoid Arthritis	0.3	0.5	1.2	0.7	1.1	-0.5	-0.1	-0.6	-0.5	-0.7	0.5	-0.7	-0.9
Schizophrenia (2014)	0.3	0.7	4.4	-2.1	0.7	-0.8	-0.6	-0.3	0.1	-0.2	0.6	0.6	0.7
Ulcerative Colitis	0.3	0.5	1.5	-0.3	0.2	-0.0	-0.7	0.0	1.0	0.5	0.8	1.2	0.8
Blood Eosinophil Count	0.3	2.1	5.2	-0.0	2.1	-1.5	-2.3	-2.3	0.9	0.4	0.0	1.8	0.6
Sensitivity / hurt feelings	0.3	0.5	2.1	0.3	-0.5	-0.2	0.2	0.8	0.5	1.4	1.0	0.5	0.3
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	1.1	-0.7	-0.2	1.1	0.6	-0.5	-0.3	-0.7	-0.3	-0.9	-0.5
Serious illness, injury or assault to yourself	0.3	0.3	1.3	1.1	0.1	-0.5	-0.6	-0.1	-0.6	-0.5	-0.1	-0.4	-0.7
Chronic bronchitis/emphysema (father)	0.3	0.4	1.1	-0.0	-0.4	0.9	0.6	-1.1	0.0	-0.8	-0.5	-0.3	0.3
Qualifications: None of the above	0.3	0.6	2.2	-0.4	-0.4	1.3	1.5	0.4	-0.1	-0.2	-1.0	-0.5	-0.4
Diabetes (self-reported)	0.3	0.4	1.3	0.1	0.8	-0.6	-0.5	1.1	-0.8	0.7	-0.1	-0.6	-0.2
Alcohol intake versus 10 years previously	0.3	0.5	1.6	0.4	0.6	-0.0	0.6	0.7	-0.2	0.6	-1.3	-1.2	0.1
Length of working week for main job	0.3	0.3	1.6	0.1	0.4	0.1	0.1	0.0	1.3	-0.2	0.6	1.1	0.1
Breastfed as a baby	0.3	0.3	1.1	1.0	0.3	-0.5	-0.2	-0.6	0.4	-0.5	0.9	0.4	-0.1
Tense / ‘highly strung’	0.3	0.5	0.9	0.6	0.9	-0.8	0.4	0.8	0.5	0.9	0.9	-0.4	0.4
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	1.2	0.2	-0.9	1.1	0.7	-0.1	-0.6	-0.0	0.1	-1.0	-0.3
Wheeze or whistling in the chest in last year	0.3	0.5	1.3	-0.8	-1.1	0.1	-0.3	0.5	-0.9	-1.0	-0.8	-0.5	-0.2
Mouth/teeth dental problems: Loose teeth	0.3	0.4	0.9	0.1	0.8	0.4	0.9	-0.7	-0.8	-0.4	-0.9	-0.4	-0.2
Comparative height size at age 10	0.3	1.9	5.4	-1.5	-2.3	2.3	1.3	-0.4	-0.1	-1.6	0.9	0.0	-0.9
Leg pain on walking	0.3	0.4	1.4	-0.1	-0.2	0.4	1.2	0.1	0.8	0.3	0.9	0.0	0.8
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	1.2	-1.1	0.4	-0.0	1.0	0.4	-0.0	0.8	0.3	0.1	0.0
Ever had bowel cancer screening	0.3	0.4	2.1	0.3	-0.6	0.5	0.1	-0.3	-0.1	-0.7	-1.4	0.3	-0.3
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	1.4	0.6	-0.5	1.2	0.9	-0.9	0.5	-0.2	-0.3	0.6	-0.4
Breast cancer (self-reported)	0.3	0.3	0.9	0.1	-0.1	0.5	-0.9	0.8	-0.6	0.4	-0.2	-0.9	0.1
Average weekly champagne plus white wine intake	0.3	0.4	1.4	1.0	-0.8	0.0	-1.2	0.1	-0.3	-0.1	0.0	0.2	-1.0
Illnesses of father: High blood pressure	0.3	0.4	1.6	-0.9	0.6	0.8	1.3	0.6	0.2	0.2	0.4	0.2	-0.3
Commuting to job workplace: Cycle	0.3	0.3	0.9	0.6	-0.1	0.9	0.5	-0.3	0.9	0.3	0.3	-0.3	0.9
LDL Cholesterol	0.2	0.3	1.4	0.3	-0.0	0.5	0.3	-0.4	-0.3	1.2	0.6	-0.0	0.4
Neuroticism (2016)	0.2	0.3	1.3	0.5	0.1	-0.2	0.4	-1.2	0.2	0.7	0.5	-0.4	-0.3
Allergy or Eczema	0.2	0.6	2.1	0.4	-0.3	1.5	1.2	-1.1	-0.7	-0.7	0.1	0.0	-0.3
Lung FEV1/FVC ratio	0.2	0.9	3.7	-0.2	1.9	-0.3	-1.9	-0.0	-0.8	0.9	-0.0	-0.2	0.4
Townsend deprivation index at recruitment	0.2	0.3	1.3	1.1	0.2	0.8	0.6	0.2	-0.2	-0.0	0.5	-0.3	-0.8
Age when periods started (menarche)	0.2	0.4	1.4	1.0	-0.1	-0.8	-0.1	1.2	0.4	-0.4	0.8	0.4	-0.1
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.7	0.1	-0.7	1.3	0.6	-0.8	-0.1	-0.9	0.3	0.3	0.4
Hearing difficulty/problems with background noise	0.2	0.4	1.3	0.7	-0.2	0.2	0.9	1.1	0.4	0.5	0.3	0.7	0.6
Illnesses of mother	0.2	0.3	0.9	-0.0	-0.5	0.9	0.8	0.3	0.8	-0.4	0.0	0.5	0.5
High blood pressure (siblings)	0.2	0.3	1.9	-0.7	1.4	-0.3	-0.3	-0.1	0.1	-0.6	-0.3	0.1	0.1
Medication: Allopurinol	0.2	0.2	0.8	-0.9	0.6	-0.1	0.4	-0.4	0.1	-0.0	-0.8	-0.4	-0.4
Medication: Seretide 50 evohaler	0.2	0.3	0.9	-0.7	-0.5	0.1	-0.1	-0.8	-0.1	-0.4	-0.9	0.4	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.8	-0.3	1.0	-0.7	0.5	0.1	1.3	0.1	0.1	0.2	0.1
Diastolic blood pressure, automated reading	0.2	0.5	1.9	-0.1	0.6	-0.5	0.1	-0.5	-1.4	0.3	-0.7	-0.7	-0.9
Blood Platelet Count	0.1	0.9	3.0	1.1	1.0	-1.1	-0.3	1.7	-0.3	0.9	-0.8	-1.1	-0.5
Blood White Count	0.1	0.7	3.8	0.2	1.9	-1.3	-0.8	-0.2	-0.3	-0.7	-0.6	-0.3	-0.1
Height	0.1	1.4	4.2	-1.4	-1.3	-0.3	-0.5	1.3	-1.4	-1.2	-0.6	-2.0	-0.1
Hair Pigment	0.1	1.7	3.4	-1.6	-0.6	0.8	1.9	-0.8	1.6	-1.0	1.4	1.7	0.6
Tanning	0.1	0.8	1.8	-0.1	1.2	-1.3	-1.2	-1.3	-0.8	1.0	0.2	-0.4	0.4
Hearing difficulty/problems: Yes	0.1	0.2	1.3	-0.4	-0.1	0.1	0.3	0.1	-0.4	0.4	1.1	0.3	0.1
Sitting height	0.1	0.5	1.3	-0.3	-0.4	0.1	-1.0	-1.1	0.1	-1.1	0.7	-0.4	0.7
Number of incorrect matches in round	0.1	0.2	0.5	-0.3	0.5	0.3	-0.0	0.1	-0.7	-0.5	-0.3	0.1	-0.7
Worrier / anxious feelings	0.1	0.2	1.3	0.2	-1.1	0.6	0.4	-0.2	0.2	-0.0	-0.2	-0.6	-0.2
Knee pain experienced in last month	0.1	0.1	0.3	-0.5	-0.4	0.5	0.5	-0.2	0.1	0.2	-0.4	-0.2	-0.0
Standing height	0.0	0.5	1.3	-1.1	-0.4	0.2	-0.8	0.2	0.1	-1.1	1.0	-0.6	0.3

Hub : Genes

C14orf159

Models

Trait associations