Best TWAS P=3.96e-10 · Best GWAS P=4.6e-08 conditioned to 0.981
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | C15orf65 | 0.16 | 0.02 | lasso | 11 | 0.03 | 2.2e-03 | -5.3 | -5.6 | 2.3e-08 | 0.83 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | C15orf65 | 0.14 | 0.04 | enet | 30 | 0.08 | 1.8e-06 | -5.5 | -5.4 | 8.0e-08 | 0.80 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Muscle Skeletal | C15orf65 | 0.07 | 0.00 | enet | 18 | 0.01 | 4.1e-02 | -2.6 | -5.4 | 5.3e-08 | 0.68 | 0.02 | 0.86 | FALSE |
| 4 | GTEx | Uterus | C15orf65 | 0.33 | 0.02 | lasso | 13 | 0.02 | 1.1e-01 | -5.3 | -6.3 | 4.0e-10 | 0.88 | 0.03 | 0.54 | TRUE |
| 5 | GTEx | Whole Blood | C15orf65 | 0.12 | 0.01 | enet | 23 | 0.06 | 6.2e-06 | -5.2 | -5.3 | 1.2e-07 | 0.68 | 0.01 | 0.98 | FALSE |
| 6 | METSIM | Adipose | C15orf65 | 0.09 | 0.03 | bslmm | 438 | 0.06 | 5.1e-09 | -4.4 | -5.5 | 4.3e-08 | 0.71 | 0.02 | 0.98 | FALSE |