TWAS hub - C15orf65

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1650	0.0510	4.0e-05	0.024	NA	0.019	NA	0.028	4.2e-03	NA	9.3e-03	NA	2.2e-03
2	GTEx	Brain Cerebellar Hemisphere	0.3960	0.1040	4.7e-04	0.082	NA	0.155	NA	0.078	3.9e-03	NA	8.6e-05	NA	4.8e-03
3	GTEx	Brain Cerebellum	0.2850	0.1000	2.9e-03	0.013	NA	0.007	NA	-0.010	1.3e-01	NA	2.0e-01	NA	9.9e-01
4	GTEx	Cells Transformed fibroblasts	0.1430	0.0430	7.8e-05	0.039	NA	0.078	NA	0.062	6.4e-04	NA	1.8e-06	NA	2.0e-05
5	GTEx	Muscle Skeletal	0.0712	0.0259	1.3e-03	0.004	NA	0.009	NA	0.004	1.1e-01	NA	4.1e-02	NA	1.2e-01
6	GTEx	Pancreas	0.1260	0.0540	7.3e-03	0.074	NA	0.048	NA	0.047	4.7e-04	NA	4.3e-03	NA	4.8e-03
7	GTEx	Skin Sun Exposed Lower leg	0.1360	0.0400	1.2e-05	0.020	NA	0.068	NA	0.058	7.6e-03	NA	2.6e-06	NA	1.6e-05
8	GTEx	Stomach	0.1900	0.0660	1.3e-03	-0.006	NA	0.009	NA	-0.004	1.0e+00	NA	1.1e-01	NA	5.8e-01
9	GTEx	Uterus	0.3270	0.1150	6.5e-03	0.021	NA	-0.012	NA	0.022	1.2e-01	NA	6.7e-01	NA	1.1e-01
10	GTEx	Whole Blood	0.1240	0.0390	1.0e-04	0.008	NA	0.056	NA	0.045	5.6e-02	NA	6.2e-06	NA	5.4e-05
11	METSIM	Adipose	0.0853	0.0234	2.9e-08	0.029	0.056	0.056	0.057	0.048	2.9e-05	7.4e-09	8.6e-09	5.2e-09	8.6e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Illnesses of siblings: Diabetes	5.6	6.8	14.8	-2.5	-1.2	-1.5	-3.8	-2.2	-3.3	-2.5	-2.8	-2.9	-1.7	-3.0
Tinnitus: Yes, but not now, but have in the past	4.7	5.1	9.4	-2.4	-2.0	-0.2	-2.9	-1.6	-2.6	-2.6	-3.1	-1.3	-1.9	-2.6
Age at first live birth	4.5	7.9	16.7	2.6	1.2	-0.2	2.9	3.9	1.9	1.2	3.3	3.4	3.4	4.1
Long-standing illness, disability or infirmity	4.5	6.9	12.4	-3.2	-2.0	-1.0	-3.1	-2.4	-2.6	-1.9	-3.5	-2.4	-2.5	-3.2
Leg predicted mass (left)	4.4	23.1	40.9	-5.6	-1.4	1.8	-5.3	-5.8	-4.3	-4.0	-4.3	-6.4	-5.5	-5.6
Leg fat-free mass (left)	4.3	22.5	39.8	-5.5	-1.4	1.7	-5.3	-5.8	-4.3	-3.9	-4.4	-6.3	-5.4	-5.5
Weight	4.1	20.2	38.8	-5.5	-1.4	1.1	-5.1	-5.8	-4.1	-3.5	-3.6	-6.2	-4.8	-5.1
Knee pain experienced in last month	4.1	6.4	14.1	-3.6	-1.0	-0.3	-2.2	-2.3	-2.4	-2.5	-2.6	-2.8	-2.2	-3.8
Basal metabolic rate	4.1	22.8	42.2	-5.7	-1.2	1.6	-5.5	-5.6	-4.4	-3.8	-4.3	-6.5	-5.3	-5.5
Arm fat-free mass (left)	4.1	20.5	38.2	-5.3	-1.0	1.8	-5.3	-5.1	-4.2	-3.4	-4.3	-6.2	-5.0	-5.3
Arm predicted mass (left)	4.1	20.8	37.7	-5.3	-1.0	1.6	-5.4	-5.2	-4.3	-3.4	-4.5	-6.1	-5.0	-5.3
Average weekly fortified wine intake	4.0	4.7	12.8	2.5	3.6	1.3	2.3	0.6	3.1	2.0	1.2	2.1	1.2	2.0
Prospective memory result	4.0	4.9	7.5	-2.2	-1.8	0.0	-2.7	-2.4	-2.2	-1.2	-2.7	-2.4	-2.4	-2.7
Osteoarthritis (self-reported)	4.0	5.2	12.2	-1.8	-1.7	1.2	-2.0	-1.7	-2.3	-3.5	-2.7	-2.3	-2.1	-3.0
Coronary Artery Disease (CAD)	3.9	4.6	12.6	-3.3	-1.4	0.4	-2.3	-1.9	-1.8	-0.3	-2.1	-3.5	-2.0	-2.0
Bilateral oophorectomy (both ovaries removed)	3.9	4.6	7.8	-2.3	-2.5	-0.8	-1.7	-2.7	-2.4	-1.5	-2.0	-2.7	-2.8	-1.2
Leg fat-free mass (right)	3.9	20.8	36.2	-5.3	-1.1	1.8	-5.0	-5.4	-4.2	-3.8	-4.2	-6.0	-4.9	-5.6
Whole body water mass	3.9	22.2	39.1	-5.6	-1.2	1.7	-5.4	-5.4	-4.4	-3.6	-4.5	-6.3	-5.3	-5.5
Leg predicted mass (right)	3.9	20.9	36.7	-5.3	-1.2	1.8	-5.0	-5.5	-4.2	-3.8	-4.2	-6.1	-4.9	-5.6
Waist circumference	3.8	13.9	24.8	-4.9	-1.3	0.6	-3.8	-4.7	-2.8	-3.4	-2.9	-4.7	-3.8	-5.0
Hip circumference	3.8	16.5	34.9	-5.1	-1.4	0.3	-4.4	-5.1	-3.8	-3.6	-2.7	-5.9	-3.9	-4.9
Whole body fat-free mass	3.8	21.7	38.6	-5.5	-1.2	1.6	-5.3	-5.5	-4.4	-3.5	-4.4	-6.2	-5.2	-5.3
Arm fat mass (left)	3.8	15.8	31.0	-4.9	-1.2	1.1	-4.3	-4.9	-3.3	-3.8	-2.5	-5.6	-4.3	-4.9
Arm fat mass (right)	3.6	14.7	29.0	-4.8	-1.1	1.1	-4.2	-4.8	-3.2	-3.4	-2.5	-5.4	-4.0	-4.8
Whole body fat mass	3.6	14.9	29.5	-5.3	-1.4	0.7	-4.2	-4.9	-3.4	-3.5	-2.1	-5.4	-3.9	-4.3
Arm fat-free mass (right)	3.5	18.1	32.2	-5.2	-0.9	2.0	-5.0	-4.8	-4.0	-3.1	-4.3	-5.7	-4.6	-4.8
Arm predicted mass (right)	3.5	17.9	31.0	-5.0	-0.9	1.8	-4.9	-4.9	-3.9	-3.4	-4.2	-5.6	-4.6	-4.7
Overall health rating	3.5	7.4	14.9	-3.5	-0.9	-0.2	-2.4	-3.3	-2.2	-2.4	-3.6	-2.3	-2.8	-3.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.5	4.1	8.0	-2.5	-1.5	0.1	-2.1	-2.8	-2.4	-2.7	-1.1	-1.9	-1.0	-2.3
Serious illness, injury or assault to yourself	3.4	4.1	9.7	-2.5	-3.0	-1.3	-3.1	-1.2	-2.5	-1.5	-2.3	-1.2	-1.1	-1.1
Trunk fat mass	3.4	14.7	29.9	-5.3	-1.6	0.5	-4.2	-4.9	-3.4	-3.5	-1.8	-5.5	-3.8	-4.2
Hair/balding pattern: Pattern 2	3.4	4.4	8.6	-2.9	-1.3	0.5	-2.3	-2.1	-2.0	-2.4	-2.3	-1.5	-2.6	-2.0
Trunk fat-free mass	3.4	19.7	35.3	-5.3	-1.1	1.1	-5.2	-5.1	-4.3	-3.1	-4.4	-5.9	-5.0	-5.1
Trunk predicted mass	3.4	19.7	34.9	-5.2	-1.2	1.1	-5.2	-5.0	-4.2	-3.2	-4.4	-5.9	-5.0	-5.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.2	6.8	11.9	2.4	2.1	1.2	1.4	2.9	3.2	2.9	2.3	3.0	2.9	3.4
Ovarian Cancer	3.1	4.1	8.3	-2.5	-2.1	-0.9	-1.9	-1.3	-2.5	-1.9	-1.1	-2.9	-2.4	-1.9
Neck or shoulder pain in last month	3.1	4.4	7.9	-2.2	-2.4	-0.8	-2.4	-1.2	-2.5	-2.1	-2.8	-2.3	-1.5	-1.9
Pack years adult smoking proportion	3.0	4.6	8.4	-2.8	-2.5	-1.2	-2.5	-2.1	-2.9	-1.2	-2.2	-2.2	-1.7	-1.3
Ever had bowel cancer screening	3.0	3.5	8.4	-2.1	-0.9	0.4	-1.7	-2.7	-1.4	-1.7	-1.2	-2.9	-2.0	-1.9
Falls in the last year	2.9	4.0	10.6	-3.2	-1.9	-0.2	-2.7	-0.6	-1.9	-1.0	-2.7	-2.2	-1.4	-1.8
Age at First Birth	2.8	4.1	9.9	2.5	-0.4	-0.0	1.8	2.0	2.1	1.6	2.6	1.7	2.2	3.1
Eye problems/disorders: Diabetes related eye disease	2.6	2.8	9.3	-1.5	-1.1	0.6	-1.5	-1.7	-1.6	-1.2	-3.1	-1.7	-2.0	-1.4
Vitamin and mineral supplements	2.6	3.5	10.2	3.2	2.3	1.4	0.6	0.9	2.4	1.5	1.3	2.7	0.2	1.6
Trunk fat percentage	2.6	10.3	21.2	-4.6	-1.7	0.3	-3.4	-4.0	-3.0	-3.2	-0.9	-4.6	-3.0	-3.3
Body mass index (BMI)	2.6	11.1	20.0	-3.8	-0.1	1.7	-3.6	-4.5	-2.4	-2.8	-2.8	-4.4	-3.8	-4.3
Alcohol usually taken with meals	2.5	4.0	10.7	1.9	-0.1	-1.4	1.4	2.3	1.8	1.2	3.3	1.1	2.1	3.2
Leg fat mass (right)	2.5	9.6	19.1	-4.1	-0.4	1.0	-3.4	-4.3	-2.4	-2.6	-2.1	-4.4	-3.1	-3.4
Arm fat percentage (left)	2.5	9.9	19.3	-4.0	-1.0	0.8	-3.1	-4.1	-2.3	-3.3	-1.2	-4.4	-3.4	-4.0
Pain experienced in last month	2.5	4.1	11.8	1.9	0.8	-1.4	1.0	1.8	1.2	1.9	2.6	2.2	2.4	3.4
Pack years of smoking	2.5	3.7	6.2	-2.5	-2.2	-0.9	-2.1	-1.7	-2.5	-1.6	-1.8	-2.0	-1.7	-1.5
Leg fat mass (left)	2.5	9.6	19.2	-4.1	-0.5	0.9	-3.4	-4.2	-2.4	-2.6	-2.1	-4.4	-3.0	-3.5
Ever had hysterectomy (womb removed)	2.4	2.7	5.8	-1.6	-1.9	-0.7	-1.0	-2.3	-2.2	-2.4	-0.7	-1.8	-1.3	-1.1
Diabetes (father)	2.4	3.0	9.5	2.3	3.1	0.4	1.6	0.8	2.3	1.3	0.3	2.5	1.3	0.2
Emphysema/chronic bronchitis	2.4	2.7	5.9	-2.4	-2.0	-0.6	-2.1	-1.1	-1.8	-1.0	-0.7	-2.2	-1.3	-1.6
Number of self-reported non-cancer illnesses	2.4	4.1	9.5	-1.8	-2.2	-1.3	-2.1	-2.3	-2.3	-0.6	-3.1	-1.4	-1.3	-2.5
Impedance of leg (left)	2.3	11.3	24.5	2.7	-0.3	-2.6	3.0	3.6	1.9	3.0	4.0	3.9	4.5	5.0
Arm fat percentage (right)	2.3	9.2	18.6	-3.9	-0.9	0.5	-3.2	-3.9	-2.3	-3.0	-1.2	-4.3	-3.1	-3.9
Pulse wave Arterial Stiffness index	2.3	2.7	8.5	-1.6	-1.3	-0.6	-1.1	-2.5	-1.9	-0.9	-2.9	-2.0	-0.5	-0.2
Body fat percentage	2.2	8.6	17.3	-4.1	-1.2	0.3	-3.1	-4.0	-2.4	-2.8	-1.0	-4.2	-2.8	-3.2
BMI	2.1	12.0	24.2	-3.3	-0.2	2.0	-3.4	-4.9	-2.3	-3.0	-2.7	-4.9	-4.3	-4.1
Impedance of leg (right)	2.1	10.2	26.5	2.6	-0.5	-2.5	2.9	3.4	1.7	2.9	3.8	3.5	3.8	5.2
Noisy workplace	2.1	2.6	9.1	-0.5	-0.1	1.0	-1.3	-0.5	-1.1	-2.4	-2.8	-0.4	-1.1	-3.0
Mouth/teeth dental problems: Dentures	2.1	3.5	6.5	-2.0	-1.0	-1.0	-2.2	-1.5	-1.8	-2.4	-1.5	-1.0	-2.5	-2.5
Breast Cancer	2.0	4.7	15.3	1.4	3.9	1.9	2.1	2.4	3.0	1.4	0.5	2.8	1.5	0.4
Illness, injury, bereavement, stress in last 2 years	2.0	2.5	5.8	1.5	1.6	0.8	1.7	2.4	1.9	2.0	2.2	0.7	-0.1	0.4
Average weekly spirits intake	1.9	2.3	7.4	-2.7	-1.3	-0.5	-0.8	-2.2	-1.0	-0.6	-1.0	-1.6	-1.6	-1.8
Alcohol intake versus 10 years previously	1.9	2.8	6.6	-1.2	-1.0	-0.4	-2.6	-1.7	-2.3	-2.3	-1.8	-1.3	-0.7	-1.7
Pulse wave peak to peak time	1.9	2.2	8.5	1.4	1.2	0.6	1.0	2.1	1.7	0.7	2.9	1.7	0.3	-0.0
Angina (self-reported)	1.9	2.5	5.6	-1.0	-2.3	-2.0	-1.8	-0.3	-1.8	-1.4	-2.4	-1.1	-0.5	-1.2
Eye problems/disorders: Glaucoma	1.9	2.3	6.5	-0.4	0.4	-0.8	-1.6	-1.2	-1.8	-2.1	-2.5	-1.3	-1.5	-1.6
Taking other prescription medications	1.8	2.7	5.5	-1.7	-1.3	-1.0	-1.8	-1.6	-1.7	-1.4	-1.7	-2.0	-1.2	-2.3
Qualifications: A levels/AS levels or equivalent	1.7	3.7	9.2	1.2	1.4	-0.5	1.7	3.0	2.2	1.6	2.2	1.8	2.1	2.3
Pulse wave reflection index	1.7	2.1	4.2	-1.4	-1.2	-1.5	-1.4	-2.0	-2.0	-0.6	-1.6	-1.9	-0.8	0.0
Reason for reducing amount of alcohol drunk: Health precaution	1.7	2.0	5.8	1.4	-0.4	-0.4	0.7	2.4	0.9	0.9	1.2	1.4	2.0	2.0
Smoking status: Current	1.7	2.6	5.2	-2.3	-1.8	-1.0	-1.8	-2.1	-2.1	-1.1	-1.4	-1.9	-0.7	-0.4
Alcohol drinker status: Previous	1.7	1.9	3.5	1.6	1.9	1.3	1.3	0.2	1.2	1.6	1.1	1.8	1.4	1.2
Number of full brothers	1.6	2.0	8.2	-1.0	0.1	-0.3	-2.9	-1.5	-1.2	-1.4	-1.8	-0.9	-0.3	-1.6
Wheeze or whistling in the chest in last year	1.6	2.8	6.6	-1.2	-0.6	1.2	-2.2	-1.1	-1.1	-2.6	-2.2	-1.1	-1.9	-2.0
Chest pain or discomfort	1.6	2.3	4.8	-1.3	-0.2	0.2	-1.4	-1.0	-1.8	-2.1	-1.9	-1.4	-2.2	-1.6
Average weekly champagne plus white wine intake	1.6	2.3	6.7	0.8	0.8	-0.5	1.7	1.9	2.5	2.6	1.3	0.9	1.0	0.9
Ever depressed for a whole week	1.6	2.0	4.3	-1.7	-1.2	0.0	-1.0	-1.9	-1.6	-2.1	0.2	-1.5	-1.7	-0.9
Impedance of whole body	1.6	8.2	17.1	2.0	-1.7	-2.9	2.6	3.1	1.2	2.0	3.9	2.9	3.6	4.1
Ulcerative Colitis	1.5	2.2	4.6	2.0	2.2	0.7	1.3	1.2	1.3	0.6	1.7	1.8	1.2	1.4
Systolic Blood Pressure	1.5	7.6	15.0	2.8	2.0	-1.5	3.6	2.1	3.0	2.8	1.0	3.7	3.9	2.4
Hearing difficulty/problems with background noise	1.5	2.4	5.7	-1.5	0.6	0.8	-0.9	-1.6	-1.1	-2.4	-1.8	-1.5	-1.4	-2.2
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.4	5.9	-2.4	-1.7	-1.7	-1.2	-1.3	-1.3	-2.1	-1.3	-1.4	-0.7	-1.5
Qualifications: College or University degree	1.5	4.7	12.6	1.6	1.4	1.1	2.6	2.9	2.3	1.7	3.6	1.0	1.9	2.4
Supplements: Calcium	1.5	1.6	5.4	-1.0	-1.3	0.0	-0.0	-2.3	-1.6	0.3	-0.9	-2.0	-1.1	-1.1
Hearing difficulty/problems: Yes	1.4	2.2	7.7	-1.5	-0.4	-0.8	-0.9	-0.9	-1.2	-2.8	-1.7	-1.0	-1.4	-2.1
Angina	1.4	1.9	5.6	-0.5	-2.3	-2.4	-1.4	-0.0	-1.4	-0.8	-2.2	-0.5	-0.1	-0.6
Townsend deprivation index at recruitment	1.4	2.0	8.9	-1.6	0.4	-0.1	-1.2	-3.0	-1.4	-1.1	-0.8	-1.1	-0.6	-1.8
Relative age voice broke	1.4	2.1	5.7	-1.4	-1.2	-2.4	-0.5	-1.3	-1.8	-1.9	-1.1	-1.1	-0.0	-1.6
Number of incorrect matches in round	1.4	2.4	8.9	2.1	-0.6	-0.6	1.5	3.0	0.3	-1.1	2.5	0.9	0.9	0.6
Medication: Paracetamol	1.4	2.2	10.8	-2.0	0.7	0.2	-1.2	-1.4	-1.1	-1.1	-1.4	-0.6	-0.6	-3.3
Diabetes (mother)	1.3	1.7	4.5	-1.0	0.1	1.2	-1.0	-1.6	-1.3	-1.3	-2.1	-1.1	-1.2	-1.5
Mouth/teeth dental problems	1.3	2.0	3.6	1.7	1.0	0.9	1.3	1.3	1.3	1.8	1.0	1.3	1.9	1.7
Illnesses of siblings	1.3	1.8	5.8	1.2	0.8	2.1	2.4	1.4	0.7	0.4	0.9	1.5	0.4	1.4
Lung cancer (father)	1.3	1.6	3.7	1.9	0.5	1.2	0.9	0.9	1.1	0.8	1.6	1.4	0.4	1.9
Tense / ‘highly strung’	1.3	2.2	5.6	-2.0	-2.4	-1.6	-1.4	-2.2	-1.2	0.7	-0.8	-1.4	-0.8	0.2
Medication: Paracetamol	1.3	2.2	11.0	-1.7	0.5	1.0	-1.0	-1.6	-0.8	-1.1	-1.9	-0.4	-0.4	-3.3
Number of children fathered	1.3	1.5	3.6	-0.7	-1.0	-1.5	-1.4	-1.9	-0.9	-1.6	-0.1	-0.8	-1.0	-1.6
Suffer from ‘nerves’	1.3	2.0	8.1	-1.5	-2.8	0.2	-1.7	-1.3	-1.3	-0.0	-1.8	-1.1	-0.9	-0.0
Mineral and other dietary supplements	1.3	1.8	5.3	1.8	2.3	0.5	0.6	0.5	1.7	0.6	0.8	1.7	1.2	1.5
Pain type(s) experienced in last month: Hip pain	1.3	1.6	4.1	-0.6	0.3	1.4	-1.8	-0.8	-0.4	-1.5	-2.0	-1.3	-0.5	-1.7
Schizophrenia (2018)	1.2	2.5	7.6	-1.1	-1.5	0.5	-2.1	-0.1	-2.8	-1.9	0.7	-1.5	-0.4	-2.3
HbA1C	1.2	1.3	6.2	-0.6	-0.4	-0.1	-1.6	-1.3	-1.5	0.7	-2.5	-0.9	0.0	-0.3
Lung FVC	1.2	6.3	16.4	2.6	1.0	0.5	2.2	2.3	2.9	2.9	2.7	2.6	1.9	4.1
Hand grip strength (left)	1.2	3.1	7.9	2.3	1.4	2.0	0.6	2.1	1.4	2.4	1.1	1.0	0.7	2.8
Current tobacco smoking	1.2	1.9	4.0	-2.0	-1.5	-0.9	-1.6	-2.0	-1.8	-0.5	-1.4	-1.4	-0.6	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.6	8.6	-1.2	-1.7	-2.9	-0.9	-0.7	-0.8	0.4	-1.3	-0.2	0.9	0.7
Stomach or abdominal pain in last month	1.2	1.5	3.8	-1.9	-1.1	-0.6	-1.3	-1.0	-0.5	-1.6	-1.4	-0.6	-0.9	-1.7
Qualifications: O levels/GCSEs or equivalent	1.2	2.0	4.1	1.2	2.0	0.2	0.9	1.2	1.9	1.4	0.8	2.0	1.4	1.2
Headache pain in last month	1.2	2.0	5.6	-1.1	-1.7	0.2	-1.3	-1.1	-1.2	-0.7	-2.4	-0.4	-2.0	-1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.5	4.7	-1.3	-1.7	-0.2	-1.2	-2.2	-1.7	-0.7	-1.1	-0.5	-1.3	-0.1
Medication for pain relief, constipation, heartburn	1.2	2.1	10.5	1.5	-0.2	-0.9	1.3	1.2	0.8	1.6	1.6	0.6	0.8	3.2
Age at last live birth	1.2	1.7	6.3	0.9	0.2	0.4	0.9	1.5	-0.1	0.0	1.9	1.2	2.5	1.9
Leg pain on walking	1.2	1.4	3.8	-1.1	1.1	1.7	-0.8	-1.1	-0.9	-1.2	-0.6	-1.5	-0.6	-2.0
Commuting to job workplace: Car/motor vehicle	1.2	1.3	5.9	1.2	0.9	0.5	1.0	2.4	1.1	0.2	-0.3	1.2	1.6	-0.0
Back pain experienced in last month	1.2	1.7	4.3	-0.7	-0.5	1.0	-1.3	-2.1	-0.9	-0.5	-1.3	-1.4	-1.8	-1.8
Number of operations (self-reported)	1.2	1.8	7.1	-0.5	-0.4	-0.2	-0.3	-2.7	0.2	-0.6	-1.6	-0.9	-2.2	-1.9
Schizophrenia vs Biploar Disorder	1.1	1.5	3.3	-1.4	0.9	-0.6	-1.4	-1.0	-1.5	-1.5	-1.4	-0.2	-0.7	-1.8
Body Mass Index (BMI) (2010)	1.1	1.5	5.1	-1.7	-0.9	-0.4	-1.3	-2.3	-0.9	-0.3	-1.3	-1.6	-0.9	-0.5
Hand grip strength (right)	1.1	3.1	8.2	2.1	1.6	1.7	1.1	1.0	1.8	2.7	1.6	0.7	0.3	2.9
Heel bone mineral density (BMD) T-score, automated (right)	1.1	2.4	6.5	-0.7	0.7	1.1	-2.2	-2.1	-1.3	-1.2	-0.5	-1.1	-2.5	-2.1
Happiness	1.1	1.4	3.4	1.1	1.7	0.6	0.5	0.4	1.0	0.1	1.8	1.8	1.0	1.3
Standing height	1.1	11.1	23.6	-4.5	-2.8	-1.2	-4.1	-3.5	-4.3	-1.8	-2.3	-4.9	-2.5	-2.5
Ever highly irritable/argumentative for 2 days	1.1	1.3	4.3	-1.2	-0.4	0.1	-1.4	-0.6	-0.6	-1.5	-1.1	-0.7	-2.1	-1.4
Leg fat percentage (right)	1.1	4.0	9.5	-2.7	-0.0	0.5	-2.1	-3.1	-1.3	-1.7	-1.1	-2.9	-2.1	-2.0
Ever smoked	1.1	2.0	6.0	-1.4	-2.5	-1.2	-1.2	-0.9	-1.7	-1.3	-1.6	-1.6	-0.2	-0.6
Leg fat percentage (left)	1.1	4.0	9.1	-2.8	-0.1	0.4	-2.1	-3.0	-1.3	-1.7	-0.9	-2.9	-1.9	-2.2
Cholesterol lowering medication	1.1	1.6	4.0	-1.7	-0.7	-1.6	-1.3	-1.3	-0.7	-0.9	-2.0	-0.9	0.4	-1.4
Heart attack/myocardial infarction (self-reported)	1.1	1.4	5.0	-2.1	-0.5	-2.2	-1.0	0.6	-0.9	-0.2	-1.5	-0.6	0.4	-0.6
Prostate Cancer	1.0	1.4	2.8	-1.3	-1.2	-0.4	-0.7	-1.6	-0.9	-1.7	-0.8	-1.6	-1.0	-1.1
Schizophrenia (2014)	1.0	2.1	6.3	-0.5	-1.1	1.0	-1.9	-0.2	-2.2	-2.1	0.4	-1.1	-0.4	-2.5
Height	1.0	19.6	39.3	-4.8	-3.3	-0.7	-6.3	-4.5	-5.8	-2.7	-4.2	-6.2	-3.2	-3.9
Other serious medical condition/disability diagnosed by doctor	1.0	1.4	6.3	-1.0	-0.9	-0.9	-1.3	-0.6	-0.7	-0.6	-2.5	-1.4	-0.3	-1.0
Medication: Metformin	1.0	1.4	2.7	-1.4	-0.7	-0.7	-0.7	-1.0	-1.4	-1.4	-1.7	-1.0	-1.2	-1.6
Heart attack	1.0	1.3	5.0	-2.1	-0.4	-2.2	-0.8	0.6	-0.8	-0.2	-1.5	-0.4	0.5	-0.4
Diabetes (self-reported)	1.0	1.6	4.9	-1.3	-0.8	-2.2	-1.3	-1.4	-1.0	-1.5	-1.0	-0.8	-1.1	-0.8
Impedance of arm (right)	1.0	4.6	12.9	1.1	-1.8	-2.9	1.9	2.4	0.4	1.1	3.6	1.4	2.4	2.5
Blood clot in the leg (DVT)	1.0	1.4	4.8	0.1	1.9	2.2	0.6	-0.9	0.5	1.7	0.5	-0.2	-1.2	-0.6
Chronic bronchitis/emphysema (mother)	1.0	1.2	2.2	-1.3	-0.1	-0.6	-1.1	-0.1	-1.4	-1.5	-0.7	-1.3	-1.3	-1.1
High blood pressure (siblings)	1.0	1.4	6.2	-0.8	-1.1	-2.5	-1.9	-0.6	-0.3	-1.1	-0.9	-0.7	0.4	-0.9
Diabetes diagnosed by doctor	1.0	1.6	2.7	-1.5	-1.4	-1.6	-1.2	-1.3	-1.2	-1.0	-1.2	-1.1	-1.2	-1.2
Asthma (self-reported)	1.0	2.0	3.8	-0.8	-0.4	1.1	-1.7	-1.3	-2.0	-1.7	-1.6	-1.2	-1.4	-1.5
Illnesses of father: High blood pressure	1.0	1.2	3.2	0.7	0.9	0.5	1.5	1.0	1.2	0.3	0.8	1.8	1.8	0.1
Deep venous thrombosis (DVT) (self-reported)	1.0	1.2	4.2	0.1	1.8	2.0	0.4	-1.0	0.5	1.5	0.7	-0.1	-1.3	-0.5
High blood pressure (mother)	0.9	1.3	5.7	0.2	1.2	-1.3	0.9	1.0	1.3	0.7	-0.3	2.4	1.0	0.6
Father’s age at death	0.9	1.2	2.2	1.5	0.9	0.3	1.4	1.2	0.8	-0.1	1.4	1.5	1.0	0.8
Exposure to tobacco smoke at home	0.9	1.0	2.6	-1.0	-0.1	1.1	-0.5	-1.1	0.0	-0.6	-0.9	-1.6	-0.9	-1.6
Eye problems/disorders: None of the above	0.9	1.1	6.9	0.2	-1.5	0.2	-0.0	0.1	-0.0	0.9	2.6	-0.1	0.6	1.2
Commuting to job workplace: Walk	0.9	1.0	4.0	-1.1	-0.9	-0.6	-1.0	-2.0	-0.7	-0.4	-0.1	-1.2	-1.3	-0.3
Osteoporosis (self-reported)	0.9	1.1	3.2	0.3	-1.7	-1.5	-0.3	0.0	-0.4	1.3	-1.8	0.9	1.1	0.2
Hearing aid user	0.9	1.0	4.0	-1.1	-0.9	-0.9	-1.0	0.7	-1.0	-2.0	-0.2	-0.2	-0.8	-1.1
Alcohol drinker status: Never	0.9	1.0	3.4	-1.3	-1.2	0.4	-1.3	-0.1	-0.5	-0.1	1.2	-0.8	-1.8	-0.8
Basal cell carcinoma (self-reported)	0.9	1.0	4.0	-0.3	0.5	0.2	-1.6	-2.0	-0.5	-0.1	-2.0	-0.4	-0.5	0.3
Bipolar Disorder or Schizophrenia	0.8	2.0	4.2	-0.3	-1.4	0.8	-1.8	0.1	-1.7	-1.7	2.1	-1.0	-0.6	-2.0
Respiratory disease	0.8	1.8	4.4	-1.0	-1.1	0.4	-1.8	-0.7	-1.7	-1.1	-1.1	-1.4	-2.1	-1.4
Frequency of depressed mood in last 2 weeks	0.8	1.1	3.0	-0.8	-0.8	-1.6	-1.3	-0.3	-0.7	0.9	-1.7	0.3	1.0	0.9
Past tobacco smoking	0.8	1.4	5.8	1.0	2.4	1.9	0.3	0.6	0.7	1.2	1.3	0.9	-0.4	0.2
Had other major operations	0.8	1.0	3.2	0.1	0.6	-0.4	-0.6	-1.8	0.1	-0.2	-1.8	-0.3	-1.3	-1.2
Financial difficulties in last 2 years	0.8	1.1	4.1	-0.3	-0.6	1.1	-2.0	-1.5	-0.9	-0.4	-1.2	-1.2	-0.3	-0.5
Impedance of arm (left)	0.8	3.7	10.7	0.7	-2.5	-2.5	1.6	1.8	0.0	0.5	3.3	1.1	2.0	2.3
Length of working week for main job	0.8	0.9	4.0	0.2	1.8	2.0	1.1	-0.3	0.7	-0.7	0.5	0.1	-0.1	0.1
Gout (self-reported)	0.8	1.1	4.7	-1.0	-2.2	-1.9	0.8	0.4	-0.5	-0.5	-1.0	-0.3	0.2	-0.1
Mouth/teeth dental problems: Loose teeth	0.8	1.0	3.1	0.3	1.1	1.5	1.8	-0.1	1.2	0.5	1.4	0.1	-0.1	0.7
Medication: Omeprazole	0.8	0.9	3.8	-1.0	-1.5	-2.0	-0.7	-1.2	-0.6	0.1	0.1	-0.3	0.7	0.3
Comparative height size at age 10	0.8	4.6	14.4	-3.4	-2.2	-0.0	-2.6	-1.5	-2.6	0.1	-0.4	-3.8	-1.8	0.1
Supplements: Vitamin C	0.8	1.0	2.9	-1.6	-1.7	-0.7	-0.6	-0.4	-0.7	-0.3	0.3	-1.7	0.0	-0.5
Breast cancer (self-reported)	0.8	1.0	3.4	-0.4	-0.8	-1.5	-0.9	0.4	-1.2	-1.8	-0.2	-0.9	-0.9	-0.6
Guilty feelings	0.8	1.1	3.5	0.2	-1.1	-1.9	0.6	0.5	0.9	1.3	0.3	1.0	0.7	1.7
Unable to work because of sickness or disability	0.8	1.1	4.3	-1.0	-0.5	-0.4	-0.2	-2.1	-1.0	-0.5	-1.5	0.0	-1.4	-0.8
Bipolar Disorder (2011)	0.7	0.6	1.8	0.3	-1.1	0.6	-0.5	1.0	0.4	1.3	1.0	-0.7	0.5	0.4
Lupus	0.7	1.1	3.4	1.6	0.3	0.8	1.3	0.4	0.8	1.2	0.1	1.1	1.8	0.7
Rheumatoid Arthritis	0.7	1.0	2.5	-1.0	-0.8	0.7	-0.9	-0.8	-0.8	-1.6	-0.5	-1.4	-0.9	-0.9
Supplements: Zinc	0.7	0.7	2.7	-0.4	-1.6	0.5	0.0	-1.0	-1.1	0.8	0.1	-0.6	-1.0	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.7	3.5	0.0	1.7	1.3	-1.5	-1.8	-0.5	-0.9	-0.4	-0.5	-1.9	-1.8
Multivitamins +/- minerals	0.7	0.9	4.0	-1.4	-1.2	-2.0	0.6	-0.0	-0.9	0.2	-0.8	-0.6	0.3	-0.4
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	3.4	-0.3	-0.6	1.1	-0.7	-1.8	-0.7	-0.8	-0.0	-0.4	-1.2	-1.2
Hair/balding pattern: Pattern 4	0.7	1.6	4.3	1.0	1.8	0.2	1.3	1.0	0.8	0.9	1.5	1.2	2.1	1.2
Loud music exposure frequency	0.7	0.8	5.1	-0.9	-2.3	0.7	-0.4	0.6	-0.4	-1.0	-0.0	-0.9	-0.0	0.1
Birth weight	0.7	1.4	2.4	-0.6	-1.5	-0.5	-1.5	-1.6	-0.9	-0.8	-0.7	-1.3	-1.5	-1.4
Exposure to tobacco smoke outside home	0.7	0.9	4.0	-0.4	0.3	2.0	-0.7	-0.9	-0.7	-1.4	-0.7	-0.3	-0.2	-1.1
Medication: Ibuprofen	0.7	0.8	2.4	-1.4	-0.0	-0.9	-0.6	-0.6	-0.9	-1.0	-0.4	-0.1	-1.0	-1.5
Illnesses of father: None of the above (group 1)	0.7	0.9	1.8	-0.6	-1.3	0.8	-1.2	-0.6	-1.1	-0.7	-0.2	-1.3	-1.4	-0.4
Risk taking	0.7	1.0	4.1	-0.7	-1.5	-0.7	-0.2	-2.0	-0.4	-0.8	-0.5	-0.6	-1.5	-0.4
Fractured/broken bones in last 5 years	0.7	0.9	4.6	-1.0	-0.2	-1.2	-0.4	-0.4	-0.8	-0.9	-2.1	-1.2	-0.2	0.1
Age started oral contraceptive pill	0.7	0.9	2.7	0.9	0.7	0.1	1.6	1.4	1.1	-0.2	1.2	0.9	0.7	0.1
Diastolic blood pressure, automated reading	0.7	2.1	4.3	0.4	1.9	-1.6	1.6	0.2	2.1	1.7	0.9	1.6	1.5	1.3
Depression (Nagel 2018)	0.6	0.8	3.4	-0.2	-0.9	-0.8	-0.8	-0.2	-0.5	1.0	-1.8	0.6	1.0	1.0
Alzheimer’s Disease (in mother)	0.6	0.7	2.3	0.2	-0.5	-0.8	-0.5	0.2	-0.7	1.5	-1.1	-0.3	-0.7	-1.3
Fasting Glucose	0.6	0.7	1.3	-0.7	1.0	0.9	-1.0	-1.0	-0.7	-0.5	-1.1	-0.9	-0.0	0.4
Smoking Status	0.6	1.3	3.7	-1.4	-1.9	-1.1	-0.6	-1.1	-1.1	-1.0	-1.8	-0.7	0.2	-0.2
Medication for hormone replacement therapy	0.6	0.6	1.6	-0.9	-1.1	-0.6	-0.5	-0.8	-1.3	0.3	-0.2	-0.5	-0.4	-1.1
Medication: Atenolol	0.6	0.7	3.3	-0.7	-0.4	-0.9	0.3	1.3	0.5	-0.5	0.6	0.5	1.8	0.8
Nervous feelings	0.6	1.0	3.7	0.0	-0.3	-0.3	1.4	-0.0	1.2	1.9	1.4	0.6	0.6	1.2
Fluid intelligence score	0.6	1.2	6.2	0.4	0.6	-0.5	0.8	-0.2	0.9	1.0	1.6	0.8	0.7	2.5
Time employed in main current job	0.6	0.7	1.4	1.2	0.8	-0.5	1.2	-0.0	0.5	0.9	0.6	0.8	-1.2	0.4
Worrier / anxious feelings	0.6	1.2	3.4	1.2	0.1	-0.2	1.4	0.8	1.2	0.3	0.9	1.6	0.6	1.8
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.7	-0.5	-1.3	-0.8	-0.7	-1.1	-1.6	-0.2	-0.4	-0.5	0.6	0.5
Asthma	0.6	1.2	2.6	-0.7	-0.3	1.1	-1.4	-1.1	-1.6	-1.0	-1.2	-0.9	-1.3	-1.1
Medication: Ventolin 100micrograms inhaler	0.6	0.7	2.7	-0.2	0.2	0.7	-0.5	-0.4	-0.8	-1.6	-1.1	-0.1	-1.1	-1.1
Shortness of breath walking on level ground	0.6	0.7	2.8	0.7	1.2	1.7	0.9	-0.7	1.2	-0.1	-0.0	0.6	-0.4	0.2
Medication: Blood pressure	0.6	1.0	2.6	1.3	-0.6	-0.4	1.1	1.2	1.4	0.3	1.6	1.0	0.8	0.5
Migraine (self-reported)	0.6	0.8	3.7	-1.2	0.2	-0.5	0.3	-1.3	-1.1	0.2	-1.9	-0.3	-0.4	-0.5
Mean time to correctly identify matches	0.6	1.1	5.3	0.2	-0.5	0.2	0.6	-1.1	0.1	-1.8	0.7	-0.5	-2.3	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.4	0.5	1.5	0.7	-0.0	1.0	0.7	-0.3	0.1	0.2	1.6	0.3
Eye problems/disorders: Cataract	0.6	0.7	2.0	-1.4	-0.3	-0.5	-0.6	0.6	-0.1	-1.4	-1.0	-0.9	0.1	-1.0
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	2.9	-1.7	-0.8	-1.7	-0.3	0.9	-0.6	-1.0	-1.1	-0.9	0.1	-0.9
Wears glasses or contact lenses	0.6	0.7	2.9	-1.7	-0.4	0.1	-1.5	0.0	-1.1	-0.2	-0.8	-0.8	-0.1	0.1
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.6	0.6	-0.1	-0.9	0.2	1.6	0.0	0.4	0.8	0.2	1.0	1.6
Commuting to job workplace: Public transport	0.6	0.7	4.1	-1.0	-0.2	-1.2	0.0	-2.0	-0.2	0.3	0.8	-0.3	-0.0	0.0
Supplements: Fish oil (including cod liver oil)	0.6	0.8	3.3	-1.0	-1.8	-1.0	0.2	0.3	-0.9	0.2	-0.2	-1.0	-0.9	-0.8
Bipolar Disorder (2018)	0.5	0.8	6.1	0.9	-0.4	0.7	-0.4	0.3	0.7	-0.4	2.5	0.2	-0.6	-0.4
Alzheimer’s Disease (including proxy)	0.5	0.8	2.3	0.0	-0.6	-0.0	-1.3	0.3	-0.8	0.7	-0.5	-0.8	-1.4	-1.5
Crohns Disease (2012)	0.5	0.8	3.6	-0.5	-1.0	-0.5	-1.9	0.0	-1.6	-0.3	0.4	-0.7	-0.0	-0.0
HDL Cholesterol	0.5	0.8	3.3	1.1	0.6	1.8	0.8	1.3	-0.0	-0.5	0.7	-0.3	1.0	0.2
Triglycerides	0.5	0.7	1.9	1.0	1.4	0.8	0.7	0.4	1.3	0.2	1.0	0.6	-1.0	0.2
Type 2 Diabetes (T2D) (2018)	0.5	1.0	6.1	-0.4	0.4	-0.5	-0.3	-1.0	-0.9	-0.7	-2.5	-0.7	-0.5	-0.7
Chronotype (morning person)	0.5	1.2	5.6	-0.6	-0.7	-1.1	-0.2	0.8	0.1	1.5	-1.2	0.3	2.4	1.1
Qualifications: CSEs or equivalent	0.5	0.6	2.3	0.5	1.5	0.3	0.7	0.5	-0.0	-1.5	-0.8	0.5	0.7	0.1
Sitting height	0.5	3.4	8.1	-1.7	-1.1	-0.4	-2.2	-1.2	-2.0	-1.4	-1.9	-2.8	-0.7	-2.8
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	2.1	-1.5	-1.4	-1.1	-1.1	-0.6	-0.9	0.1	-0.8	-0.8	-0.4	0.2
Medication: Lansoprazole	0.5	0.6	2.3	-0.3	-0.7	-0.6	-1.5	-1.1	-0.8	-0.2	-0.1	-0.8	-0.6	-0.2
Illnesses of mother	0.5	0.6	2.7	0.2	-0.3	1.4	0.1	0.4	-0.2	0.3	0.8	-1.7	0.2	0.8
Heart disease (mother)	0.5	0.6	3.5	-1.9	-1.0	-0.1	-0.6	-0.5	-0.6	-0.9	-0.5	-0.0	0.0	-0.6
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.6	-0.2	0.2	1.6	0.4	1.0	0.9	0.9	-0.9	0.2	0.3	-0.5
Smoking status: Previous	0.5	0.8	2.8	0.5	-0.9	-1.3	1.0	0.9	0.6	-0.5	-0.6	0.7	1.7	0.5
Friendships satisfaction	0.5	0.6	2.2	-0.4	-0.1	0.6	-0.6	-0.7	-1.1	-1.1	-0.3	-0.9	-1.5	-0.4
Ever taken oral contraceptive pill	0.5	0.5	1.4	-1.2	0.8	-0.9	1.2	-1.1	-0.2	-0.2	-0.0	-0.3	-0.2	0.1
Mother’s age at death	0.5	0.7	3.6	-0.0	-0.3	1.2	0.5	0.2	1.2	-0.2	1.9	0.5	-0.1	0.6
Financial situation satisfaction	0.5	0.6	1.7	-1.0	-0.7	0.2	-0.2	0.2	-1.3	-1.0	-0.6	-1.3	-0.3	0.6
Medication: Atorvastatin	0.5	0.7	2.2	-0.9	-0.8	-0.9	-0.1	0.6	-0.1	1.1	-1.5	-0.6	0.7	-0.5
Commuting to job workplace: Cycle	0.5	0.6	1.7	-0.3	-1.0	0.6	-1.2	-0.2	-0.8	-0.6	-1.3	-0.5	-0.6	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.5	0.7	2.2	-0.7	-1.3	-1.5	-0.7	-1.4	-0.4	-0.4	0.3	-0.3	-0.1	-0.0
Worry (Nagel 2018)	0.4	0.8	2.8	-0.7	-1.7	-0.2	-0.3	-1.3	-0.3	0.3	-1.4	-0.4	-0.8	0.6
Alzheimer’s Disease (in father)	0.4	0.5	2.1	-0.7	-0.9	-0.1	-1.5	0.1	-0.6	-0.2	0.3	-0.7	-0.6	-0.6
Ulcerative Colitis (UC)	0.4	0.8	2.5	1.1	0.9	0.1	1.1	0.9	0.5	-0.6	1.0	1.6	0.2	0.8
Reaction Time	0.4	0.8	3.2	0.8	-0.3	0.3	1.2	-0.2	0.3	-1.5	0.6	-0.5	-1.8	-0.8
Neuroticism (2016)	0.4	0.6	3.3	-1.8	-0.7	-0.5	-0.3	-1.0	-0.8	-0.7	-0.4	-0.2	-0.7	0.3
Number of treatments/medications taken	0.4	0.7	2.9	-0.9	0.3	-0.0	-0.8	-0.7	-0.2	-0.6	-1.4	-0.1	0.1	-1.7
Age when periods started (menarche)	0.4	0.8	5.1	-0.1	-1.0	1.0	-0.4	-0.8	-0.1	-2.3	-0.2	0.4	-0.5	-1.0
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.8	-0.4	-0.3	1.0	0.2	-1.3	0.9	0.4	0.2	-0.2	-0.9	-0.5
Medication: Levothyroxine sodium	0.4	0.7	1.7	-1.3	-1.3	-1.3	-1.2	-0.1	-0.5	0.2	-0.0	-0.8	-0.5	-0.7
Qualifications: None of the above	0.4	0.9	3.1	-0.5	-1.6	-1.1	-0.5	-1.7	-0.7	0.5	-0.3	-0.4	-0.8	-0.9
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	2.1	-1.0	-0.4	-1.4	-0.4	0.8	0.1	0.5	0.6	0.4	0.7	-0.1
Medication: Ramipril	0.4	0.5	1.5	0.7	-0.7	0.0	-0.2	-0.4	0.1	0.9	1.0	0.1	1.1	1.2
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	6.0	0.5	0.3	1.0	0.2	0.8	0.6	2.0	1.0	0.9	0.6	2.4
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.0	-0.3	1.3	0.5	0.3	-0.3	-0.1	-0.6	-0.0	0.7	-0.6	-1.4
Glaucoma (self-reported)	0.4	0.5	2.0	1.2	0.9	-0.2	0.2	-0.3	-0.3	-0.5	-1.4	-0.1	-0.9	0.1
Worry too long after embarrassment	0.4	0.6	2.5	0.7	-0.4	0.3	0.9	0.5	0.6	0.7	0.9	1.0	0.3	1.6
Health satisfaction	0.4	0.5	2.0	0.1	1.0	1.4	0.3	-0.9	0.9	0.2	-0.3	0.2	-0.4	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.7	-0.0	-1.3	-0.6	-0.0	-0.1	-1.2	-0.9	0.1	-0.8	-0.3	-0.2
Family relationship satisfaction	0.4	0.5	1.4	-0.5	0.9	-0.1	-0.8	-1.0	-1.2	-1.2	-0.0	-0.6	-0.1	-0.6
Illnesses of father: Heart disease	0.4	0.6	2.2	-1.5	-0.8	-0.9	0.6	0.8	-0.4	-0.6	-0.3	-0.9	0.5	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	2.5	-0.8	-0.2	0.7	-0.6	-1.5	-1.6	-0.1	-1.1	-0.8	-0.6	-0.6
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.6	0.1	-0.1	-1.6	-0.0	0.6	0.3	0.5	0.2	-0.2	0.6	1.2
Mood swings	0.4	0.8	2.1	0.5	0.1	-1.0	0.7	-0.8	0.9	0.9	0.3	1.3	1.4	0.8
Miserableness	0.4	0.7	2.9	0.3	-0.1	0.6	1.7	0.6	0.5	0.1	1.7	0.5	0.2	1.1
Medication: Blood pressure	0.4	0.7	4.0	-0.7	0.7	-0.4	-0.9	0.0	0.9	0.3	-2.0	0.1	1.0	-0.6
High cholesterol (Self-reported)	0.4	0.6	3.1	-0.8	-0.0	0.9	-0.6	-0.0	0.0	-0.1	-1.8	0.2	-0.6	-1.3
Medication: Bendroflumethiazide	0.4	0.6	1.5	1.0	0.9	0.8	-0.8	-0.1	1.2	1.2	0.3	1.0	0.0	0.1
Crohns Disease (2017)	0.3	0.6	1.8	-0.9	-0.3	0.2	-1.4	-0.3	-0.9	-1.2	-0.2	-0.1	-1.0	-0.5
Major Depression (MDD)	0.3	0.3	0.8	-0.1	-0.8	-0.9	0.5	0.0	0.8	0.8	-0.7	0.5	-0.1	0.4
LDL Cholesterol	0.3	0.5	1.3	-0.2	-0.8	0.1	-0.6	-0.4	-0.5	-0.5	-1.1	-0.9	-1.0	-0.8
Type 2 Diabetes (T2D) (2012)	0.3	0.4	1.7	-1.3	-0.1	-1.0	-0.6	0.5	0.2	0.4	-0.1	-0.3	0.1	-0.7
Lung FEV1/FVC ratio	0.3	1.4	4.3	0.3	1.6	1.4	1.9	0.6	2.1	0.3	0.8	0.8	0.7	0.5
Relative age of first facial hair	0.3	0.6	2.7	0.7	1.6	-1.1	0.7	0.2	-0.4	-0.1	-0.5	0.2	0.5	-1.1
Systolic blood pressure, automated reading	0.3	0.8	5.1	0.1	0.6	-2.2	0.6	-0.2	0.9	0.8	-0.0	0.7	0.9	0.9
Severe depression (siblings)	0.3	0.4	1.1	0.2	-0.3	0.2	-0.2	-1.0	-0.3	1.0	-1.0	-0.1	-0.7	-0.5
Maternal smoking around birth	0.3	0.4	2.0	1.0	0.6	-0.2	0.0	0.2	0.5	0.1	-0.6	0.2	-1.4	-0.2
Supplements: Glucosamine	0.3	0.4	2.6	0.1	0.4	1.6	-0.1	-0.3	-0.3	-0.5	0.4	-0.5	0.9	-0.4
Chronic bronchitis/emphysema (father)	0.3	0.3	1.1	1.1	0.1	-0.4	0.0	-0.1	0.5	0.9	0.6	0.3	-0.2	0.6
Had menopause	0.3	0.3	1.5	-0.2	-1.2	-1.0	0.0	-0.3	-0.3	0.0	0.3	-0.7	0.0	0.5
Pulse rate	0.3	0.5	3.4	-0.4	0.5	1.8	-0.4	0.7	0.5	-0.4	-0.4	-0.2	-0.2	-0.4
Medication: Cholesterol lowering	0.3	0.4	2.9	0.1	-0.4	-0.4	0.1	1.7	-0.0	-0.4	-0.2	0.8	1.0	0.2
Depression (self-reported)	0.3	0.4	1.8	0.5	-0.1	0.6	0.5	-0.1	0.3	0.7	-0.6	0.2	-1.3	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.8	4.8	0.2	-0.2	0.6	0.2	0.1	0.2	2.2	0.3	0.7	0.6	1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	2.0	-0.5	-1.0	-0.4	-0.0	-0.4	0.4	1.4	0.4	0.4	-0.5	1.1
Medication: Amlodipine	0.3	0.5	2.2	0.1	-0.7	0.8	-0.5	0.1	0.3	-0.3	-1.5	0.6	0.3	-1.0
Medication: Allopurinol	0.3	0.4	0.8	-0.1	-0.8	-0.8	0.4	0.9	0.7	-0.5	-0.4	0.5	0.4	0.4
Medication: Seretide 50 evohaler	0.3	0.4	1.6	0.8	0.2	0.1	0.4	1.3	0.3	-0.4	0.0	1.0	0.5	-0.0
Pulse rate, automated reading	0.3	1.0	3.2	-1.3	0.3	0.1	-1.0	-1.0	-0.5	-1.1	-0.9	-0.6	-0.8	-1.8
Medication: Aspirin	0.3	0.5	1.5	-0.7	-0.9	-0.6	-1.2	0.0	-0.7	-0.2	-0.5	-0.5	-0.4	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.6	-0.2	0.4	-0.6	-1.3	-0.7	-0.6	-0.4	0.5	-0.5	0.3	-0.3
Average weekly red wine intake	0.3	0.4	2.0	-0.2	-1.1	-1.4	-0.1	0.2	-0.3	-0.6	0.6	-0.4	0.3	0.3
Loneliness, isolation	0.3	0.4	1.3	-0.4	0.1	0.4	-0.9	-1.1	-0.2	-0.8	0.2	0.2	-0.5	0.7
Medication for cholesterol	0.3	0.4	1.2	-0.1	-0.7	0.3	0.2	-0.0	-0.7	-0.8	1.0	-0.6	-1.1	0.6
Medication: Aspirin	0.3	0.3	1.0	-0.4	-0.9	-1.0	-0.9	0.6	-0.6	0.2	-0.2	-0.4	0.2	-0.5
Medication: Gliclazide	0.3	0.3	1.1	0.6	1.0	0.7	-0.6	-0.0	-0.5	-0.6	0.2	-0.1	-0.4	-0.8
Average weekly beer plus cider intake	0.3	0.4	2.9	-0.4	0.4	-0.4	-0.5	-1.7	-0.3	-0.1	-0.7	-0.1	-0.1	-0.2
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.4	0.4	0.0	1.0	0.5	0.1	0.4	-1.2	-0.2	-0.2	-0.2	-0.6
Myopia	0.3	0.5	2.0	-0.6	-0.4	-0.8	-0.5	-0.5	-0.4	0.4	1.2	-0.1	-0.1	1.4
Vascular/heart problems diagnosed by doctor	0.3	0.8	2.8	0.9	1.5	1.7	1.2	0.1	-0.0	-0.0	1.1	0.7	-0.4	0.5
Intelligence (Savage-Jansen 2018)	0.2	0.6	2.4	-0.3	-0.4	-0.8	-0.0	0.6	1.0	1.0	1.5	-0.1	-0.2	1.0
Neuroticism (Nagel 2018)	0.2	0.4	1.0	0.1	-1.0	-0.0	0.4	-0.9	0.1	0.8	-0.6	0.5	-0.0	1.0
Mean Putamen Volume	0.2	0.2	1.0	-1.0	-0.0	0.4	-0.1	-0.2	-0.3	0.7	0.1	-0.5	-0.2	-0.0
Primary Biliary Cirrhosis	0.2	0.3	0.6	-0.6	-0.6	0.5	-0.6	0.5	-0.8	0.6	0.5	-0.5	0.5	0.5
Heel T-Score	0.2	1.5	5.8	-1.1	0.8	0.5	-1.9	-1.4	-0.4	-0.4	-1.1	-0.9	-2.4	-0.7
Waist Hip Ratio (WHR)	0.2	0.7	2.9	0.2	-0.3	-0.3	1.4	0.9	1.3	0.0	0.0	1.7	0.4	-0.2
Allergy or Eczema	0.2	0.6	3.3	0.3	-0.1	0.3	0.6	1.0	0.9	0.1	1.8	0.1	0.1	1.2
Neuroticism	0.2	0.4	1.6	-0.8	-1.0	-0.1	-0.1	-1.3	0.1	0.2	-0.4	0.3	-0.2	1.0
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.4	-0.4	-0.9	-0.7	1.2	0.0	0.3	0.3	-0.2	0.0	-0.3	0.6
Medication: Co-codamol	0.2	0.2	0.8	-0.2	0.0	0.0	-0.9	-0.4	-0.6	-0.6	-0.7	0.5	-0.3	0.2
High blood pressure	0.2	0.6	1.3	-0.7	-1.0	-1.0	-1.1	-0.1	0.4	-0.1	-1.1	-0.4	0.1	-1.0
Forced vital capacity (FVC)	0.2	0.8	4.4	0.1	-0.3	0.9	-0.8	-0.2	-0.2	1.8	0.1	0.2	0.1	2.1
Pain all over the body in last month	0.2	0.3	1.2	0.1	0.2	0.7	0.0	-0.5	-0.2	1.1	-0.6	-0.1	-0.5	0.6
Medication: Simvastatin	0.2	0.3	1.1	-0.3	-0.6	-0.0	-0.7	0.7	0.1	-1.0	-0.7	0.5	0.8	-0.3
Neuroticism score	0.2	0.5	2.1	0.0	-0.6	0.0	0.5	-0.7	0.8	0.7	0.1	0.8	0.4	1.5
Hair/balding pattern: Pattern 3	0.2	0.4	1.7	-0.3	-0.9	1.3	-0.2	0.8	-0.3	-0.0	-0.2	-0.6	-0.2	-0.0
Number of live births	0.2	0.3	1.1	-0.0	0.9	-0.0	-0.6	-0.3	-0.2	-0.2	-1.1	0.2	0.8	-0.2
Birth weight of first child	0.2	0.4	1.7	0.4	0.3	-1.0	0.3	-0.6	-0.0	1.3	-0.3	0.6	-0.1	-0.4
Peak expiratory flow (PEF)	0.2	0.4	1.2	-0.4	0.5	0.9	-0.6	1.1	0.1	0.8	-0.3	0.1	-0.5	0.6
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.0	0.3	-0.1	-0.3	0.0	-0.5	-0.2	0.7	0.7	-0.2	1.0	0.8
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.0	-0.0	1.0	0.3	0.1	-0.9	-0.1	0.4	-0.6	-0.1	-0.5	0.2
Forced vital capacity (FVC), Best measure	0.2	0.8	4.2	-0.2	-0.9	0.6	-0.4	-0.2	-0.3	2.0	0.2	0.1	0.2	1.9
Alcohol intake frequency.	0.2	0.4	1.8	0.4	1.3	0.5	0.2	-0.2	0.7	0.5	-0.2	1.1	-0.0	-0.7
Number of full sisters	0.2	0.2	0.6	-0.6	-0.7	0.1	-0.3	-0.5	-0.5	-0.3	-0.2	-0.1	-0.8	0.1
Had major operations	0.2	0.2	0.6	0.1	-0.3	-0.2	0.4	-0.3	0.7	0.8	0.8	-0.0	-0.7	0.3
Irritability	0.2	0.3	1.0	-0.3	-0.5	0.1	-0.5	-0.9	0.5	1.0	-0.0	0.4	-0.2	0.5
Heart disease (siblings)	0.2	0.2	0.7	0.3	-0.1	-0.8	-0.1	-0.8	0.7	0.3	-0.0	0.1	0.6	0.1
Depressed Affect (Nagel 2018)	0.1	0.2	1.7	0.1	-0.0	0.4	0.2	-1.3	-0.1	0.1	-0.2	0.2	-0.3	0.2
Irritable Bowel Disease (IBD)	0.1	0.2	1.0	0.0	0.6	0.0	0.2	0.3	-0.3	-1.0	0.2	0.9	-0.5	0.2
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.1	-0.5	-0.1	-0.5	-0.8	-1.0	0.3	0.4	0.3	-0.4	-0.6	0.3
Blood Eosinophil Count	0.1	1.2	2.6	-1.4	-0.4	-0.7	-1.3	-1.6	-0.5	-1.1	-1.1	-0.5	-0.6	-1.6
Blood Platelet Count	0.1	1.1	2.9	0.2	1.4	-0.4	1.3	-0.2	0.5	1.3	-1.4	0.8	0.9	-1.7
Blood Red Count	0.1	0.6	2.4	-0.4	0.3	0.1	-0.5	-0.2	1.1	1.3	-1.6	-0.1	0.5	0.2
Blood White Count	0.1	0.7	2.2	-1.1	-0.2	-1.5	0.7	-0.8	-0.7	-0.7	-0.8	0.0	1.2	-0.6
Cardiovascular Disease	0.1	0.5	1.7	0.3	-0.2	-0.6	-0.6	-0.0	0.2	1.0	-1.3	0.1	1.3	-0.1
Hypothyroidism (self reported)	0.1	0.3	0.9	-0.1	0.9	0.1	0.4	-0.2	0.1	0.8	-0.7	-0.3	-0.4	-0.9
Tanning	0.1	0.9	3.9	0.3	0.9	0.2	-0.7	-0.7	0.1	-1.5	-0.7	0.9	0.3	-2.0
Sensitivity / hurt feelings	0.1	0.3	1.5	0.1	0.2	-0.5	0.6	-0.2	0.3	0.5	-0.1	0.2	0.6	1.2
Fed-up feelings	0.1	0.3	1.1	-0.9	-0.3	0.4	-0.5	-1.0	-0.2	0.2	-0.3	0.2	0.3	0.5
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.5	-0.2	-0.7	-0.3	-0.2	0.7	0.3	-0.5	0.5	-0.1	-0.1	0.2
Allergy	0.1	0.3	0.6	0.7	0.1	-0.1	0.5	0.0	0.7	0.7	-0.4	0.8	0.5	0.6
Breastfed as a baby	0.1	0.2	0.7	0.2	-0.4	0.1	-0.8	0.8	0.0	0.5	-0.3	-0.0	0.1	-0.2
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	1.3	0.0	-0.1	-0.3	0.2	-0.0	0.4	1.1	-0.3	-0.5	-0.1	-0.6
Comparative body size at age 10	0.1	0.4	1.1	-0.7	0.5	-0.1	0.7	-0.3	1.0	0.2	0.5	-0.8	-0.8	0.7
Hypertension (Self-reported)	0.1	0.4	0.8	-0.5	-0.8	-0.9	-0.8	-0.0	0.5	-0.1	-0.9	-0.3	0.4	-0.6
Qualifications: nursing, teaching	0.1	0.2	0.6	0.2	0.8	-0.1	0.3	0.0	0.1	-0.1	0.8	0.3	0.4	0.4
Medication: Lisinopril	0.1	0.1	0.4	0.1	0.3	0.3	-0.1	0.3	0.6	0.1	-0.2	0.2	0.1	-0.0
Hair Pigment	0.0	1.2	4.8	0.8	-0.8	-0.5	1.4	0.6	-0.1	2.0	-0.4	-0.3	-0.0	2.2

Hub : Genes

C15orf65

Models

Trait associations