Best TWAS P=6.51e-08 · Best GWAS P=5.7e-07 conditioned to 0.628
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | TTC19 | 0.06 | 0.00 | lasso | 3 | 0.00 | 7.1e-01 | -4.6 | 5.2 | 1.8e-07 | -0.87 | 0.07 | 0.37 | FALSE |
2 | GTEx | Whole Blood | ADORA2B | 0.08 | 0.00 | lasso | 5 | 0.00 | 2.5e-01 | -3.9 | -5.1 | 2.8e-07 | 0.85 | 0.04 | 0.62 | FALSE |
3 | YFS | Blood | PIGL | 0.02 | 0.02 | blup | 279 | 0.02 | 1.5e-06 | -3.1 | -5.4 | 6.5e-08 | 0.88 | 0.20 | 0.78 | TRUE |