Hub : Genes

PIGL

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Artery Aorta 0.0880 0.0470 1.0e-03 0.030 NA 0.044 NA 0.044 8.7e-03 NA 1.9e-03 NA 1.8e-03
2 GTEx Artery Tibial 0.0807 0.0336 2.2e-05 0.098 NA 0.060 NA 0.076 4.0e-08 NA 1.9e-05 NA 1.5e-06
3 GTEx Cells Transformed fibroblasts 0.0360 0.0190 5.6e-03 0.023 NA 0.018 NA 0.001 6.7e-03 NA 1.5e-02 NA 2.4e-01
4 GTEx Skin Sun Exposed Lower leg 0.1120 0.0570 1.6e-03 0.018 NA 0.025 NA 0.014 1.2e-02 NA 3.3e-03 NA 2.2e-02
5 GTEx Testis 0.1980 0.0800 1.7e-04 0.064 NA 0.103 NA -0.001 8.7e-04 NA 2.6e-05 NA 3.7e-01
6 GTEx Whole Blood 0.0310 0.0160 2.1e-03 0.022 NA 0.025 NA 0.020 3.4e-03 NA 2.2e-03 NA 5.4e-03
7 METSIM Adipose 0.1608 0.0534 6.4e-06 0.058 0.030 0.048 0.050 0.054 4.3e-09 2.2e-05 9.1e-08 4.4e-08 1.5e-08
8 ROSMAP Brain Pre-frontal Cortex 0.0548 0.0255 2.8e-05 0.022 0.037 0.009 0.032 0.013 6.2e-04 1.2e-05 2.2e-02 5.0e-05 6.9e-03
9 YFS Blood 0.0173 0.0082 1.6e-05 0.021 0.017 0.014 0.017 0.017 1.1e-07 1.5e-06 1.4e-05 1.8e-06 2.2e-06
10 TCGA Breast Invasive Carcinoma 0.0205 0.0136 2.3e-04 0.012 0.015 0.006 NA 0.009 1.1e-03 3.5e-04 1.9e-02 NA 5.2e-03
11 TCGA Kidney Renal Clear Cell Carcinoma 0.0578 0.0274 6.7e-08 0.064 0.074 0.071 NA 0.070 1.1e-07 1.1e-08 2.1e-08 NA 2.5e-08
12 TCGA Brain Lower Grade Glioma 0.0322 0.0203 9.9e-04 0.028 0.011 -0.002 NA 0.009 3.6e-04 1.9e-02 7.1e-01 NA 2.8e-02
13 TCGA Pheochromocytoma and Paraganglioma 0.2620 0.1020 1.9e-05 0.128 0.044 0.058 NA 0.034 9.0e-06 7.4e-03 2.5e-03 NA 1.7e-02
14 TCGA Thyroid Carcinoma 0.0680 0.0380 2.0e-03 0.022 0.026 0.005 NA 0.013 3.1e-03 1.3e-03 1.0e-01 NA 1.7e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.4 0.6 1.7 0.7 1.0 0.5 1.1 -0.7 0.6 0.7 -0.1 1.3 0.7 0.6 0.9 1.1 0.3
Bipolar Disorder or Schizophrenia 0.2 0.5 1.8 0.6 0.8 1.0 0.2 -0.6 0.3 0.6 0.2 1.3 0.7 0.8 1.0 0.8 -0.1
Depressed Affect (Nagel 2018) 7.1 14.9 20.7 -3.7 -3.9 -3.9 -2.9 3.7 -3.5 -4.0 -3.8 -3.4 -3.9 -4.5 -4.2 -4.5 -3.7
Depression (Nagel 2018) 2.5 3.8 9.5 -1.3 -2.4 -2.1 -2.6 0.2 -1.4 -1.6 -1.3 -2.1 -2.2 -2.0 -0.7 -2.0 -3.1
Intelligence (Savage-Jansen 2018) 1.8 5.6 11.7 -2.2 -2.2 -2.6 -2.0 2.7 -2.3 -2.6 -3.4 -1.6 -2.1 -2.5 -2.6 -2.5 -1.2
Neuroticism (Nagel 2018) 3.2 7.6 10.8 -2.1 -2.9 -3.2 -1.8 2.3 -2.8 -2.8 -2.6 -2.5 -2.9 -3.3 -2.8 -3.1 -3.0
Schizophrenia (2018) 0.1 0.2 0.7 0.2 0.3 0.8 -0.6 -0.2 0.0 0.2 0.3 0.7 0.4 0.5 0.5 0.1 -0.4
Schizophrenia vs Biploar Disorder 1.1 1.4 3.6 0.8 1.1 1.6 0.5 -1.2 0.9 1.2 0.5 1.9 1.3 1.5 1.3 1.1 1.0
Worry (Nagel 2018) 0.1 0.2 1.0 0.2 -0.1 -0.7 0.7 -0.5 -1.0 0.1 -0.2 0.0 -0.3 -0.3 0.2 -0.0 -0.6
Alzheimer’s Disease (in mother) 1.6 1.9 3.8 -0.6 -1.6 -1.2 -1.0 1.7 -1.5 -1.8 -0.9 -0.8 -1.3 -1.4 -1.4 -1.4 -1.9
Alzheimer’s Disease (in father) 2.1 2.3 4.4 1.2 1.8 1.9 0.9 -1.6 0.7 1.7 1.2 1.6 1.4 1.7 2.1 1.8 0.5
Alzheimer’s Disease (including proxy) 0.2 0.3 0.7 0.0 0.4 0.7 -0.1 -0.3 -0.9 0.3 0.5 0.7 0.3 0.5 0.7 0.6 -0.5
Crohns Disease (2017) 0.2 0.4 1.1 0.6 0.5 -0.0 1.0 -0.9 0.5 0.3 1.1 -0.4 0.1 0.5 0.5 0.9 0.8
Irritable Bowel Disease (IBD) 0.1 0.2 0.7 0.3 -0.2 -0.8 0.7 -0.8 -0.3 -0.1 0.3 -0.7 -0.7 -0.3 0.1 0.2 -0.1
Ulcerative Colitis (UC) 0.1 0.2 1.2 0.2 -0.3 -0.7 0.6 -1.1 -0.3 0.2 -0.1 -0.4 -0.6 -0.2 0.3 -0.0 -0.3
Major Depression (MDD) 0.7 0.9 4.1 -1.4 -0.7 -1.0 -0.3 0.8 -2.0 0.1 -1.5 -0.3 -0.7 -0.3 -0.6 -0.7 0.3
Reaction Time 6.1 11.6 16.2 2.9 3.9 3.8 3.9 -2.0 2.5 3.8 2.7 4.0 4.0 3.8 2.6 3.5 3.5
Verbal and Numeric Reasoning (VNR) 2.3 5.4 12.9 -2.1 -2.4 -2.7 -1.7 1.9 -2.7 -2.3 -3.6 -1.6 -2.4 -2.4 -2.1 -2.3 -1.3
Breast Cancer 0.1 0.3 1.4 0.5 0.2 0.3 0.3 -1.2 -0.4 0.6 0.4 -0.2 0.3 0.3 0.3 0.4 0.9
Ovarian Cancer 0.3 0.4 1.1 1.1 0.3 0.5 -0.3 -0.3 -0.6 0.4 1.1 0.4 0.2 1.1 0.6 0.5 0.3
Prostate Cancer 2.9 4.1 10.0 -0.6 -2.6 -2.1 -2.2 1.9 -1.5 -2.4 -1.9 -1.2 -1.7 -2.4 -1.4 -1.9 -3.2
Age at First Birth 1.9 2.7 7.5 -2.2 -1.7 -1.8 -1.9 -0.3 -2.7 -1.2 -2.0 -1.4 -1.9 -1.3 -0.6 -1.1 -1.1
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 1.4 2.0 4.3 -0.9 -1.4 -1.2 -1.8 1.4 -1.0 -1.5 -0.8 -2.1 -1.8 -1.3 -1.2 -1.3 -1.4
Coronary Artery Disease (CAD) 0.3 0.3 1.3 -0.3 0.9 0.5 0.8 1.1 0.5 0.1 1.0 -0.0 0.0 0.0 0.0 0.0 0.0
Crohns Disease (2012) 0.1 0.1 0.5 0.1 0.6 0.3 0.2 -0.2 0.1 0.2 0.7 -0.6 0.0 0.3 0.2 0.4 0.3
Mean Putamen Volume 0.1 0.1 0.4 -0.1 0.1 0.2 -0.2 -0.1 -0.5 0.1 -0.6 0.1 -0.4 0.1 0.2 0.0 -0.0
Fasting Glucose 0.3 0.4 2.1 1.3 0.2 0.5 0.4 0.7 0.2 0.1 0.3 0.7 0.4 -0.3 0.1 -0.1 -1.5
HbA1C 0.7 0.7 2.9 1.0 0.7 0.8 1.2 -0.6 1.7 0.6 0.8 0.2 0.7 0.7 0.6 0.7 0.6
HDL Cholesterol 0.2 0.3 2.5 -1.6 0.0 0.1 -0.9 -0.4 -0.4 0.2 -1.0 0.3 0.1 0.1 0.1 0.1 0.4
LDL Cholesterol 0.3 0.4 1.1 -0.1 -0.5 -0.6 -0.0 0.5 0.1 -0.7 -1.0 -0.9 -0.8 -0.8 -0.5 -0.6 -0.9
Lupus 2.0 3.1 5.8 1.5 1.7 1.2 2.0 -2.4 1.5 1.8 1.5 1.3 1.4 1.7 2.4 2.3 1.3
Neuroticism (2016) 2.8 4.1 7.6 -1.6 -1.8 -2.0 -0.6 2.8 -0.9 -2.2 -2.3 -1.9 -1.8 -2.5 -2.6 -2.5 -1.6
Primary Biliary Cirrhosis 0.3 0.5 1.9 -1.4 -0.5 -0.6 0.3 0.9 -0.8 -0.3 -0.4 -0.7 -0.7 -0.6 -0.7 -0.6 -0.2
Rheumatoid Arthritis 4.3 5.9 11.1 2.1 2.0 2.3 1.9 -2.6 1.8 2.7 2.6 1.8 2.5 3.3 2.7 2.6 2.5
Schizophrenia (2014) 0.1 0.3 0.9 0.4 0.7 0.8 -0.3 -0.1 -0.1 0.4 0.3 0.9 0.8 0.8 0.3 0.2 0.5
Triglycerides 0.1 0.2 0.8 -0.0 0.1 0.1 0.6 -0.4 0.6 0.2 0.9 0.3 0.3 0.2 0.6 0.5 -0.1
Type 2 Diabetes (T2D) (2012) 1.4 1.6 8.3 -1.4 -1.2 -1.3 -1.4 2.9 -1.2 -1.7 -0.9 -1.4 0.0 0.0 0.0 0.0 0.0
Ulcerative Colitis 0.2 0.4 0.8 0.1 -0.8 -0.9 -0.2 0.1 -0.6 -0.3 -0.2 -0.8 -0.6 -0.9 -0.5 -0.8 -0.7
Blood Eosinophil Count 0.7 5.2 14.1 1.3 2.5 2.5 1.2 -1.7 1.0 2.7 2.7 1.7 2.3 3.1 1.4 2.3 3.8
Blood Platelet Count 0.9 10.1 14.7 3.5 3.0 3.0 3.8 -2.3 3.5 3.0 3.4 2.9 3.1 3.5 2.8 3.4 2.8
Blood Red Count 0.1 0.6 1.5 1.2 -0.6 -0.9 -0.8 -0.8 -1.2 -0.4 0.0 -1.0 -1.0 -0.3 0.2 -0.1 -0.5
Blood White Count 10.2 75.9 98.8 7.8 8.8 8.5 6.5 -9.2 8.8 9.3 9.1 7.6 8.7 9.6 9.6 9.9 7.9
Heel T-Score 0.1 0.5 3.1 -1.3 -0.5 0.1 -1.8 -0.2 -1.0 -0.4 -0.0 -0.4 -0.2 0.0 0.3 0.0 0.0
BMI 3.0 17.3 48.4 -4.1 -4.5 -4.6 -3.2 2.2 -4.3 -3.8 -2.3 -7.0 -5.4 -3.9 -3.8 -4.1 -2.6
Height 0.2 4.7 8.5 -2.9 -2.4 -2.5 -2.9 1.7 -1.8 -2.4 -1.5 -2.3 -1.9 -1.8 -2.1 -2.4 -0.9
Waist Hip Ratio (WHR) 2.7 12.2 24.0 3.1 3.6 3.8 4.2 -2.3 4.2 3.3 2.3 4.9 4.1 3.1 3.2 3.5 1.9
Systolic Blood Pressure 1.7 8.3 13.5 2.1 3.4 3.5 2.2 -1.4 1.9 3.0 3.3 2.7 3.5 3.3 2.2 2.9 3.7
Smoking Status 1.8 4.4 12.6 0.7 1.9 1.8 0.7 -2.3 2.0 2.7 2.4 0.5 1.9 2.6 1.7 2.2 3.5
Allergy or Eczema 0.5 1.4 3.1 -0.4 -1.3 -1.3 -1.0 1.5 -1.0 -1.3 -0.4 -1.1 -1.2 -1.1 -1.8 -1.5 -0.6
Cardiovascular Disease 1.8 5.8 9.8 2.4 2.7 2.6 2.5 -2.8 1.1 3.1 1.7 1.6 2.2 2.8 2.5 2.5 2.3
Hypothyroidism (self reported) 0.6 1.3 3.6 0.6 1.0 0.8 0.5 -1.9 1.4 1.4 0.8 0.4 0.8 1.3 1.7 1.2 0.7
Respiratory disease 0.8 1.7 3.6 -1.4 -1.3 -1.6 -0.5 1.6 -0.8 -1.0 -0.5 -1.6 -1.1 -1.3 -1.9 -1.9 -0.5
Type 2 Diabetes (T2D) (2018) 0.4 0.8 1.7 -0.8 -1.0 -0.5 0.4 0.3 -0.8 -0.7 -1.3 -1.0 -0.9 -1.1 -0.6 -1.2 -1.3
Lung FEV1/FVC ratio 0.1 0.3 1.9 -0.8 0.2 0.0 -0.2 -0.7 -0.3 0.5 -1.4 0.4 -0.0 -0.1 0.6 0.1 -0.4
Lung FVC 4.3 21.8 28.0 4.0 5.2 4.9 3.9 -3.6 4.0 4.7 4.9 4.9 5.3 5.1 4.5 5.2 4.7
Neuroticism 2.5 6.0 10.0 -2.2 -2.4 -2.5 -0.6 2.5 -3.2 -2.1 -3.2 -1.3 -2.3 -2.7 -3.0 -3.0 -1.8
Chronotype (morning person) 1.3 3.1 10.7 -1.8 -1.7 -1.6 -2.5 0.7 -0.8 -1.7 -1.2 -3.3 -2.5 -1.4 -1.3 -1.5 -0.8
Hair Pigment 0.2 4.7 11.2 -1.6 -3.1 -2.3 -3.3 1.1 -0.6 -2.5 -1.4 -2.4 -2.6 -2.1 -1.7 -2.2 -1.9
Tanning 0.2 2.5 4.6 0.8 2.0 1.7 1.7 -1.1 0.9 1.8 0.5 2.1 2.1 1.5 1.4 1.9 1.6
Hand grip strength (left) 0.4 1.0 2.3 -0.2 1.2 1.0 -0.3 -0.9 0.7 1.1 0.1 1.2 1.2 1.2 1.0 1.1 1.5
Number of treatments/medications taken 0.5 0.8 2.1 0.8 0.6 1.3 0.7 0.5 1.4 0.7 0.7 1.1 1.4 0.9 -0.0 0.3 1.1
Average weekly spirits intake 0.4 0.5 2.1 -1.5 -0.1 -0.4 -1.3 -0.4 -0.9 0.2 -0.2 -0.8 -0.5 0.4 0.0 -0.1 1.0
Sensitivity / hurt feelings 0.2 0.4 1.2 -0.2 -0.6 -0.6 0.1 1.0 -0.7 -0.8 -0.4 -0.1 -0.3 -0.7 -0.6 -0.8 -1.1
Frequency of depressed mood in last 2 weeks 2.7 3.7 8.9 -1.2 -2.1 -2.0 -2.5 1.8 -0.3 -2.3 -0.9 -1.7 -1.9 -2.1 -1.5 -2.2 -3.0
Hearing difficulty/problems: Yes 1.6 2.4 4.9 0.7 1.4 1.8 1.3 -1.6 1.6 2.1 1.2 2.2 1.9 1.3 1.2 1.2 1.7
Relative age of first facial hair 0.2 0.5 3.3 0.6 0.7 0.9 0.2 0.1 0.3 0.2 0.3 1.8 0.6 0.8 0.3 0.7 0.4
Other serious medical condition/disability diagnosed by doctor 0.2 0.3 0.8 0.5 0.3 0.6 0.5 0.3 0.9 0.2 0.8 0.8 0.7 0.2 -0.0 0.2 0.4
Ever used hormone-replacement therapy (HRT) 2.4 3.1 5.2 -1.1 -1.8 -1.3 -2.1 1.4 -2.3 -1.9 -1.7 -1.9 -1.9 -1.6 -1.3 -1.7 -2.0
Ever had hysterectomy (womb removed) 0.3 0.3 1.4 -0.1 0.4 0.9 0.5 0.4 1.2 0.4 -0.0 0.4 0.5 0.5 0.5 0.4 -0.5
Systolic blood pressure, automated reading 0.2 0.5 1.5 -1.1 -0.5 -0.2 -0.7 0.8 -0.6 -0.3 0.2 -1.2 -0.5 -0.2 -0.9 -0.7 0.7
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 0.8 0.2 0.3 0.2 0.4 0.1 0.8 -0.2 0.9 -0.1 0.2 0.0 0.4 0.1 -0.5
Angina 2.4 3.2 9.2 -0.7 -2.2 -1.6 -1.8 1.3 -0.8 -2.1 -0.8 -1.9 -1.9 -1.9 -1.4 -2.2 -3.0
Medication for hormone replacement therapy 0.4 0.4 1.6 -1.0 -0.2 0.1 -1.3 1.0 0.0 -0.8 0.3 -0.9 -0.5 -0.1 -0.2 0.0 -0.4
Vitamin and mineral supplements 0.4 0.5 2.6 -0.5 0.2 0.1 -0.8 -1.6 -0.3 0.3 -1.1 -0.3 -0.8 0.3 1.0 0.8 0.2
Supplements: Zinc 0.7 0.7 2.3 0.7 0.7 0.5 0.3 -0.7 1.1 1.0 0.2 0.7 0.8 1.2 0.7 0.9 1.5
Medication: Co-codamol 0.2 0.3 1.2 -0.4 0.4 0.7 -0.2 0.3 0.7 0.2 0.2 -0.5 0.2 0.3 -0.7 -0.0 1.1
Medication: Metformin 0.1 0.2 0.7 -0.3 -0.4 0.2 0.3 0.4 0.8 -0.3 0.1 -0.3 -0.1 -0.2 -0.2 -0.5 -0.8
Diabetes (father) 0.9 1.2 4.6 -0.4 -1.3 -1.3 0.0 -0.4 -0.4 -0.8 -1.8 -0.7 -1.0 -1.3 0.3 -0.6 -2.2
Diabetes (mother) 0.3 0.4 1.5 0.4 0.7 0.5 0.8 0.5 0.5 0.5 0.2 0.3 0.7 0.6 -0.2 0.3 1.2
Severe depression (siblings) 0.2 0.2 1.0 -1.0 -0.3 -0.0 -0.7 0.6 0.2 -0.6 -0.1 0.1 -0.1 -0.1 -0.1 -0.1 -0.5
Pack years adult smoking proportion 0.2 0.3 1.2 -0.1 -0.8 -0.7 -0.1 0.3 0.1 -0.5 0.2 -1.1 -0.4 -0.7 -0.7 -0.8 -0.5
Impedance of leg (right) 2.8 13.8 35.2 4.9 3.8 3.4 4.3 -2.0 4.5 3.2 1.2 5.9 4.6 2.9 3.2 3.5 1.3
Leg fat-free mass (left) 3.6 18.9 41.2 -5.7 -4.3 -4.4 -4.8 3.1 -4.8 -4.0 -2.0 -6.4 -5.1 -3.5 -4.2 -4.3 -1.8
Trunk fat percentage 1.9 7.6 11.3 -2.9 -2.9 -2.9 -1.9 2.0 -2.8 -2.7 -2.7 -3.4 -3.2 -2.8 -2.8 -2.9 -2.2
Hand grip strength (right) 0.9 2.5 6.2 0.7 2.1 1.7 0.6 -0.9 1.2 1.8 1.1 1.5 2.0 2.0 1.2 1.6 2.5
Townsend deprivation index at recruitment 4.6 6.4 8.9 2.4 2.9 2.6 2.8 -2.8 1.9 3.0 2.2 2.4 2.5 2.5 2.6 2.8 1.9
Current tobacco smoking 1.6 2.6 7.3 0.4 1.6 1.9 0.4 -0.9 2.2 1.9 1.9 0.8 2.0 1.8 0.9 1.4 2.7
Average weekly fortified wine intake 0.3 0.3 2.1 -1.5 -0.0 0.1 -1.1 -0.1 -0.5 0.3 -0.1 0.5 0.3 -0.0 -0.0 -0.1 0.3
Maternal smoking around birth 0.3 0.5 1.4 0.7 0.7 1.0 1.0 0.1 1.2 0.1 1.1 0.4 0.6 0.1 0.2 0.6 0.5
Fed-up feelings 1.6 2.9 6.1 -1.6 -1.6 -1.0 -1.6 2.4 0.1 -1.6 -2.0 -1.0 -1.2 -1.9 -2.3 -2.5 -1.5
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.3 1.5 -0.2 -0.6 -0.2 -1.1 0.3 0.4 -0.2 -0.1 -0.6 -0.4 -0.3 -0.2 -0.8 -1.2
Relative age voice broke 0.8 1.2 2.4 1.1 1.1 1.4 1.2 -0.2 0.8 0.7 0.8 1.5 1.3 1.2 0.6 1.3 1.2
Taking other prescription medications 0.3 0.5 1.5 0.4 0.2 1.1 0.4 0.6 1.2 0.3 1.0 0.3 1.1 0.5 -0.5 0.0 1.0
Age when periods started (menarche) 2.1 5.1 7.9 2.4 2.3 2.2 1.8 -2.2 1.1 2.8 1.5 2.8 2.6 2.5 2.0 2.2 2.5
Bilateral oophorectomy (both ovaries removed) 0.6 0.7 2.1 -0.8 -0.9 -0.1 -1.2 0.8 -1.3 -0.6 -1.4 -0.6 -0.8 -0.4 -0.6 -0.7 -0.6
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.5 1.7 -0.9 -0.5 -0.6 -1.0 -0.4 -1.3 -0.7 -1.0 -0.2 -0.8 -0.2 0.4 0.2 -0.4
Tinnitus: Yes, but not now, but have in the past 0.7 0.8 2.9 -1.2 -0.5 -1.4 0.3 -0.2 -0.6 -0.5 -1.0 -1.7 -0.9 -1.0 -0.3 -0.5 -0.6
Qualifications: CSEs or equivalent 1.0 1.3 5.2 -1.2 -0.1 -0.5 -1.8 -1.9 0.1 0.1 0.4 -0.4 -0.7 0.4 2.3 1.1 -1.5
Serious illness, injury or assault to yourself 0.5 0.6 1.3 0.6 0.8 1.1 0.4 -0.3 1.1 0.7 0.6 1.2 1.0 0.7 0.3 0.6 0.8
High blood pressure 3.8 10.5 16.2 2.6 3.6 3.8 2.7 -2.7 2.3 3.9 2.9 3.0 3.5 4.0 2.9 3.2 3.6
Hayfever, allergic rhinitis or eczema 2.0 4.3 7.4 -1.6 -2.2 -2.1 -2.1 2.6 -1.6 -2.5 -0.5 -2.2 -2.1 -1.9 -2.7 -2.4 -1.5
Multivitamins +/- minerals 0.7 0.9 3.2 -0.1 -1.0 -0.8 -0.2 1.8 -0.0 -1.3 0.1 -0.3 -0.2 -1.1 -1.1 -1.1 -1.4
Stomach or abdominal pain in last month 1.3 1.6 3.6 1.5 1.5 1.1 0.9 -1.2 1.9 1.4 1.5 0.5 1.3 1.1 1.1 1.2 0.7
Supplements: Glucosamine 1.2 1.5 3.0 1.2 1.0 1.0 1.2 -0.8 1.7 1.4 0.9 1.7 1.5 1.3 0.8 1.0 1.2
Diverticular disease/diverticulitis (self-reported) 0.5 0.6 2.4 0.5 0.6 0.3 0.4 -0.4 1.6 0.0 0.9 0.9 0.6 0.1 1.0 0.7 -0.9
Medication: Atenolol 0.3 0.4 1.1 1.0 0.4 0.7 0.7 -0.0 0.6 -0.1 0.8 0.5 0.5 0.3 0.7 0.8 -0.5
Medication: Levothyroxine sodium 0.8 1.4 2.4 0.4 1.1 1.1 0.8 -1.5 1.5 1.4 1.3 0.6 1.2 1.4 1.4 1.2 1.1
Sitting height 2.7 18.9 24.6 -4.8 -4.4 -4.9 -4.9 3.6 -4.7 -4.3 -3.4 -5.0 -4.7 -3.9 -4.3 -4.6 -2.5
Chronic bronchitis/emphysema (father) 0.3 0.3 1.8 1.4 0.0 0.6 0.8 -0.2 0.1 0.6 0.4 0.4 0.7 0.3 -0.3 -0.4 0.2
High blood pressure (mother) 0.4 0.5 3.1 0.2 0.3 0.1 0.0 -1.3 -0.2 0.8 -0.6 0.6 0.4 0.4 1.8 0.8 -0.4
Body mass index (BMI) 2.7 11.3 26.2 -3.7 -3.5 -3.4 -2.7 2.2 -3.3 -3.2 -2.3 -5.1 -4.2 -3.3 -3.1 -3.5 -2.4
Impedance of leg (left) 2.5 12.0 31.9 4.6 3.4 3.1 3.9 -2.0 4.2 2.9 1.2 5.7 4.3 2.6 3.1 3.3 0.9
Leg predicted mass (left) 3.6 19.2 41.0 -5.7 -4.3 -4.4 -4.8 3.1 -4.9 -4.0 -2.1 -6.4 -5.1 -3.6 -4.2 -4.4 -1.9
Trunk fat mass 2.5 10.5 18.8 -3.7 -3.4 -3.3 -2.6 2.3 -3.5 -3.1 -2.7 -4.3 -3.8 -3.1 -3.3 -3.4 -2.1
Waist circumference 2.0 7.2 13.0 -2.7 -3.0 -2.7 -2.1 1.8 -2.5 -2.7 -2.0 -3.6 -3.3 -2.7 -2.3 -2.8 -2.5
Number of incorrect matches in round 1.0 1.6 3.5 -1.0 -1.4 -1.4 -1.1 0.9 -1.9 -1.1 -1.0 -1.2 -1.4 -1.3 -1.3 -1.6 -1.0
Past tobacco smoking 1.1 2.0 7.0 -0.5 -0.9 -0.6 0.1 2.7 -0.8 -1.8 -1.6 0.5 -0.4 -1.9 -1.8 -1.6 -1.8
Alcohol usually taken with meals 1.1 1.7 3.3 -0.1 -1.8 -1.5 -0.6 1.4 -1.5 -1.4 -0.5 -1.1 -1.4 -1.3 -1.5 -1.7 -1.2
Nervous feelings 0.6 1.1 2.8 1.3 0.9 0.4 0.5 -1.7 0.9 1.5 1.1 0.6 0.8 1.1 1.3 1.0 0.6
Frequency of tenseness / restlessness in last 2 weeks 3.3 5.1 7.8 -2.2 -2.5 -2.1 -2.0 2.5 -1.5 -2.7 -1.0 -1.8 -2.2 -2.4 -2.5 -2.8 -2.7
Hearing difficulty/problems with background noise 0.3 0.5 1.3 -0.8 -0.8 -0.2 -0.9 0.3 -0.5 -0.7 -0.2 0.0 -0.5 -1.1 -0.7 -0.7 -0.9
Hair/balding pattern: Pattern 2 0.2 0.3 1.2 -0.4 0.4 0.1 0.4 -0.2 1.1 0.0 0.3 0.4 0.3 0.4 0.7 1.0 0.7
Had menopause 0.3 0.3 1.4 -0.8 -0.3 -0.6 0.1 1.2 -0.6 -0.5 0.3 -0.1 -0.1 -0.5 -1.0 -0.6 -0.2
Had other major operations 0.2 0.2 1.2 -0.8 -0.5 -0.3 -1.1 0.4 0.2 -0.1 0.1 -0.7 -0.2 0.2 -0.3 -0.3 0.6
Forced vital capacity (FVC) 1.5 5.6 11.4 1.5 2.7 2.2 0.7 -1.7 1.8 2.4 3.4 2.0 2.7 3.0 2.4 2.6 2.9
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.1 3.3 -1.1 -0.7 -0.8 -1.3 0.9 -1.8 -1.5 -1.1 -0.5 -1.1 -0.8 -0.8 -0.5 -0.5
Ever unenthusiastic/disinterested for a whole week 2.2 2.7 4.3 -1.7 -1.6 -1.2 -1.5 2.1 -0.7 -2.1 -1.5 -0.8 -1.3 -1.9 -2.0 -2.0 -1.8
Qualifications: None of the above 0.7 1.6 4.0 1.4 0.6 0.7 1.0 -1.8 1.9 1.1 2.0 -0.2 0.8 1.2 1.7 1.2 0.2
Financial difficulties in last 2 years 1.5 2.0 5.0 -1.9 -1.7 -1.7 -1.3 0.8 -0.8 -1.1 -0.6 -2.2 -1.5 -1.4 -1.4 -1.7 -0.8
Mouth/teeth dental problems 0.9 1.3 4.7 -2.2 -0.9 -1.4 -1.4 -0.1 -1.7 -0.5 -0.6 -1.8 -1.3 -0.4 -0.4 -0.5 0.2
Heart attack 0.2 0.2 0.6 -0.4 -0.6 -0.2 -0.4 0.6 0.7 -0.7 -0.3 -0.1 -0.0 -0.2 -0.1 -0.2 -0.8
Allergy 2.4 5.5 8.4 1.7 2.7 2.4 2.0 -2.6 1.3 2.7 1.0 2.8 2.6 2.2 2.9 2.9 2.2
Pain all over the body in last month 0.3 0.3 2.1 0.1 0.6 0.6 0.6 -0.1 1.5 0.0 -0.4 0.3 0.0 -0.1 0.3 0.6 0.1
Diabetes (self-reported) 0.7 1.1 2.3 -0.6 -1.2 -0.8 0.4 1.0 -0.7 -1.1 -1.0 -1.5 -1.0 -1.3 -1.2 -1.4 -1.1
Hayfever/allergic rhinitis (self-reported) 0.8 1.1 5.0 -0.1 -0.7 -0.2 -0.8 2.2 0.2 -1.3 -1.0 -0.1 -0.6 -0.7 -1.6 -1.4 -1.0
Medication: Ramipril 0.4 0.5 1.9 1.2 -0.2 0.0 0.5 -0.6 0.3 0.5 1.4 -0.7 0.3 0.8 0.1 0.1 0.9
Medication: Simvastatin 2.3 3.4 7.0 -0.6 -2.3 -1.5 -0.6 1.6 -1.4 -2.3 -2.2 -1.3 -1.8 -2.2 -1.7 -2.1 -2.6
Fluid intelligence score 0.4 0.8 3.8 0.0 -0.2 -0.2 0.2 2.0 -0.7 -0.8 -1.7 0.9 0.2 -0.6 -1.2 -0.6 0.2
Illnesses of siblings 1.6 2.3 3.9 -1.4 -1.8 -1.7 -1.4 1.3 -1.7 -1.4 -2.0 -1.3 -1.4 -1.4 -1.7 -1.7 -0.5
Neuroticism score 2.4 4.9 10.8 -1.7 -2.2 -2.0 -0.8 3.3 -1.7 -2.3 -2.1 -1.2 -1.7 -2.5 -3.1 -3.0 -2.0
Weight 3.2 15.6 32.6 -4.6 -4.1 -4.1 -3.8 2.9 -3.9 -3.8 -2.2 -5.7 -4.7 -3.6 -3.8 -4.1 -2.6
Impedance of arm (right) 1.0 4.7 13.3 2.7 2.3 2.2 2.3 -0.9 1.9 1.8 1.1 3.7 2.9 1.9 1.7 2.2 1.3
Arm fat percentage (right) 2.0 7.8 16.7 -3.1 -2.8 -2.7 -1.8 2.1 -3.0 -2.6 -2.2 -4.1 -3.4 -2.7 -3.0 -3.0 -1.8
Trunk fat-free mass 1.4 8.0 20.1 -3.9 -2.8 -2.9 -3.4 1.8 -2.9 -2.4 -0.6 -4.5 -3.3 -2.1 -2.7 -2.8 -0.9
Hip circumference 3.1 13.3 25.2 -3.7 -3.9 -3.8 -3.6 2.3 -3.9 -3.6 -2.4 -5.0 -4.5 -3.5 -3.3 -3.7 -2.7
Time employed in main current job 0.5 0.6 1.5 0.4 0.7 0.8 1.2 0.9 0.5 0.6 0.3 1.0 1.2 0.4 -0.8 -0.5 0.8
Alcohol intake versus 10 years previously 0.6 0.9 3.8 1.3 0.8 1.0 1.2 -0.1 1.9 0.4 1.3 0.7 1.1 0.2 0.2 0.4 0.1
Father’s age at death 0.3 0.4 1.1 0.3 -0.9 -0.5 0.1 0.4 0.7 -0.7 -0.6 -1.0 -0.6 -0.6 -0.6 -0.7 -0.4
Worrier / anxious feelings 0.2 0.3 1.6 0.8 0.3 0.1 0.7 0.3 -0.0 -0.2 0.1 1.3 0.5 -0.4 0.0 0.0 -0.9
Frequency of tiredness / lethargy in last 2 weeks 1.0 1.6 3.8 -1.2 -1.0 -0.6 -0.6 2.0 -1.2 -1.3 -1.2 -0.6 -0.7 -1.2 -1.8 -1.8 -1.1
Falls in the last year 0.6 0.8 1.9 -1.2 -0.7 -0.8 -0.4 0.9 0.1 -0.8 -0.6 -1.4 -0.9 -0.8 -1.2 -1.2 -0.5
Hair/balding pattern: Pattern 3 0.5 0.8 3.1 1.4 0.6 0.4 0.4 -1.8 0.4 1.2 0.1 0.4 0.4 0.9 1.4 0.9 0.2
Number of live births 0.7 1.0 1.9 -0.7 1.4 0.7 0.9 -1.2 1.1 1.2 1.0 1.1 1.1 0.7 0.7 1.0 1.3
Forced expiratory volume in 1-second (FEV1) 1.2 4.2 6.7 1.1 2.4 1.7 0.7 -2.1 1.2 2.1 2.6 1.6 2.1 2.6 2.5 2.5 2.4
Pulse rate 0.2 0.4 2.8 -1.7 0.0 -0.1 -0.3 -0.3 -0.1 0.0 -1.3 0.2 -0.3 0.2 0.3 0.1 0.0
Happiness 0.2 0.3 1.0 -0.4 0.1 0.4 -0.7 0.8 1.0 -0.5 -0.4 0.8 0.2 -0.0 -0.0 0.0 -0.8
Noisy workplace 0.5 0.7 2.0 0.3 0.4 0.8 1.4 -0.8 1.4 1.0 1.1 -0.0 0.8 0.5 0.7 0.5 0.2
Qualifications: A levels/AS levels or equivalent 1.4 3.1 5.5 -1.2 -1.7 -2.0 -0.9 2.2 -2.3 -1.9 -1.7 -0.5 -1.3 -1.8 -2.0 -2.2 -1.8
Serious illness, injury or assault of a close relative in last 2 years 1.5 1.7 4.8 -0.8 -0.9 -0.6 0.5 2.2 -0.6 -1.9 -1.7 0.3 -0.5 -1.7 -1.8 -1.3 -1.4
Mouth/teeth dental problems: Dentures 0.3 0.5 1.5 0.2 0.1 0.6 1.2 1.1 0.8 0.3 -0.1 0.3 0.6 -0.1 -1.2 -0.8 0.7
Asthma 2.3 4.6 8.4 -2.5 -2.2 -2.4 -1.6 2.2 -1.2 -2.2 -1.2 -2.9 -2.4 -1.9 -2.5 -2.5 -1.4
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.2 0.9 0.9 0.4 0.7 -0.2 0.6 0.8 0.0 0.0 -0.3 -0.2 0.3 -0.4 -0.1 0.5
Medication: Cholesterol lowering 0.7 1.1 4.3 -0.2 -1.3 -0.8 -0.3 0.4 -0.8 -1.2 -1.9 -0.2 -0.7 -1.1 -0.4 -1.0 -2.1
Depression (self-reported) 2.4 2.9 4.8 -1.9 -2.1 -1.8 -2.2 1.3 -2.1 -1.5 -1.5 -0.8 -1.5 -1.5 -1.5 -2.0 -1.4
Medication: Lansoprazole 1.3 1.5 3.6 -0.8 -1.6 -1.4 -1.2 -1.4 -1.0 -0.9 -0.9 -1.9 -1.7 -1.0 0.3 -0.5 -1.5
Prospective memory result 4.8 5.9 9.3 2.0 2.5 2.5 1.6 -2.9 1.7 3.0 2.9 2.1 2.6 2.4 2.5 2.5 2.1
Lung cancer (father) 0.3 0.4 1.1 -1.0 0.2 0.2 0.9 0.8 0.7 0.3 0.2 0.2 0.8 0.2 -0.7 -0.3 0.7
Illnesses of mother 0.7 0.9 2.9 0.7 1.1 1.0 1.0 -0.8 1.2 0.9 1.2 -0.0 0.5 1.0 0.1 0.8 1.7
Forced expiratory volume in 1-second (FEV1), Best measure 2.0 6.4 9.7 1.6 2.8 2.1 1.0 -2.6 1.7 2.6 2.6 2.2 2.6 3.1 3.1 3.1 3.0
Pulse wave Arterial Stiffness index 0.1 0.1 0.4 -0.2 -0.2 0.1 -0.0 -0.3 -0.2 0.4 0.6 -0.1 0.1 0.4 -0.1 0.1 0.6
Impedance of arm (left) 0.7 3.2 10.4 2.1 1.9 1.8 1.8 -0.6 1.5 1.5 0.5 3.2 2.5 1.6 1.4 1.7 0.9
Arm fat mass (right) 2.6 10.9 22.8 -3.8 -3.4 -3.4 -2.6 2.4 -3.5 -3.1 -2.1 -4.8 -4.0 -3.1 -3.4 -3.5 -2.0
Trunk predicted mass 1.4 8.1 20.1 -3.9 -2.8 -2.9 -3.3 1.9 -3.0 -2.4 -0.7 -4.5 -3.3 -2.2 -2.7 -2.8 -1.0
Standing height 0.3 2.9 6.2 -2.5 -1.7 -2.0 -2.4 1.7 -1.8 -1.6 -0.3 -1.8 -1.4 -1.0 -1.9 -1.8 -0.5
Length of working week for main job 0.7 0.8 2.2 0.0 1.1 1.2 0.2 -0.0 1.3 0.9 0.7 0.8 1.2 1.0 0.1 0.4 1.5
Exposure to tobacco smoke at home 2.1 2.3 4.5 1.8 2.1 1.8 2.1 -0.5 0.6 1.7 1.3 1.1 1.7 1.7 1.1 1.3 1.5
Breastfed as a baby 1.0 1.3 3.3 1.8 0.7 1.3 0.8 -0.4 1.7 1.1 1.2 1.6 1.0 1.1 0.8 0.7 0.3
Tense / ‘highly strung’ 0.5 0.9 1.4 -1.2 -0.8 -1.0 -0.3 1.1 -0.5 -1.1 -0.5 -0.9 -1.1 -0.9 -1.0 -0.9 -1.2
Seen doctor (GP) for nerves, anxiety, tension or depression 2.9 4.5 7.7 -1.6 -2.4 -2.4 -1.7 2.0 -1.9 -2.1 -2.1 -1.7 -2.1 -2.2 -2.4 -2.8 -1.8
Hair/balding pattern: Pattern 4 1.2 2.9 5.0 1.3 2.0 2.2 1.8 -0.6 1.9 1.7 1.7 1.8 2.2 1.5 1.1 1.6 1.7
Birth weight of first child 1.0 1.8 3.3 -1.8 -1.3 -1.3 -1.3 1.7 -0.7 -1.1 -1.8 -0.9 -1.0 -0.9 -1.8 -1.6 -0.4
Peak expiratory flow (PEF) 0.2 0.5 2.3 -1.5 -0.4 -1.1 -0.7 0.3 -1.2 -0.4 -0.3 -0.7 -0.5 -0.4 -0.4 -0.4 0.3
Pulse wave reflection index 0.2 0.3 1.9 1.0 -0.0 0.0 0.1 -0.6 0.6 0.3 1.4 -0.4 0.2 0.2 0.4 0.4 0.1
Ever highly irritable/argumentative for 2 days 7.5 9.0 11.5 -3.4 -3.1 -3.1 -2.9 2.4 -2.9 -3.3 -2.1 -2.8 -3.3 -3.4 -2.6 -3.1 -3.3
Loud music exposure frequency 0.4 0.4 2.6 -0.5 -0.1 -0.0 -0.7 -0.5 0.5 -0.1 1.6 -0.4 -0.3 0.3 0.7 0.7 0.0
Qualifications: O levels/GCSEs or equivalent 1.2 1.9 5.9 -1.9 -0.9 -1.6 -0.7 1.2 -2.4 -1.2 -1.4 -0.9 -1.4 -1.1 -1.3 -1.1 -0.6
Mouth/teeth dental problems: Bleeding gums 2.2 2.9 7.0 2.6 1.4 1.7 1.6 -1.4 2.0 1.4 1.9 1.9 1.7 1.3 2.0 1.8 0.1
Blood clot in the leg (DVT) 0.2 0.3 1.5 -0.1 -0.3 0.2 -0.2 0.3 -0.4 -0.3 -1.2 0.7 -0.2 -0.3 -0.1 -0.4 -1.1
Medication: Paracetamol 0.2 0.3 1.5 1.2 0.5 0.6 0.1 -0.5 0.9 0.5 0.6 0.0 0.2 0.3 0.5 0.3 0.1
Headache pain in last month 0.2 0.3 0.7 0.1 -0.3 -0.2 -0.3 0.7 0.5 -0.7 -0.5 0.1 -0.3 -0.9 -0.6 -0.6 -0.9
Medication for cholesterol, blood pressure or diabetes 0.1 0.2 0.9 0.5 0.2 -0.2 -0.0 0.4 0.2 0.0 0.9 -0.3 -0.2 0.1 -0.4 0.0 0.6
Glaucoma (self-reported) 2.9 3.4 7.6 -2.5 -1.9 -1.5 -1.2 1.8 -1.3 -1.8 -2.8 -1.3 -1.7 -1.8 -2.1 -2.2 -0.7
Gout (self-reported) 3.2 4.4 9.7 1.4 1.9 1.8 1.3 -2.8 1.4 2.1 2.3 2.3 2.1 2.2 3.1 2.6 1.0
Hypothyroidism/myxoedema (self-reported) 0.5 1.0 2.5 0.5 1.0 0.8 0.5 -1.6 1.4 1.4 0.5 0.6 0.8 1.2 1.5 1.0 0.5
Medication: Amlodipine 0.3 0.5 2.0 0.3 0.7 0.3 0.3 -1.4 -0.4 0.8 0.3 -0.0 -0.0 0.7 1.3 0.9 -0.0
Medication: Ventolin 100micrograms inhaler 0.7 0.9 2.0 -1.4 -0.8 -1.0 -1.0 1.1 -0.1 -1.2 0.9 -1.1 -0.8 -0.6 -0.9 -0.9 -0.8
Birth weight 0.1 0.2 1.1 -0.3 0.2 0.2 -0.3 -0.5 -0.7 0.2 1.0 -0.3 -0.2 0.6 0.5 0.6 0.4
Chronic bronchitis/emphysema (mother) 1.3 1.5 2.6 -0.9 -1.2 -1.3 -1.2 1.4 -1.3 -1.6 -0.1 -0.7 -0.9 -1.6 -1.1 -1.3 -1.6
High blood pressure (siblings) 1.8 2.7 5.8 0.7 1.6 1.7 0.8 -1.9 1.3 1.6 2.2 1.6 1.5 1.6 2.4 2.2 0.5
Forced vital capacity (FVC), Best measure 1.8 6.7 10.7 1.8 2.9 2.3 0.7 -2.1 1.9 2.5 3.1 2.6 2.9 3.3 2.8 3.0 3.1
Body fat percentage 1.6 6.5 10.8 -2.5 -2.7 -2.5 -1.5 1.9 -2.5 -2.5 -2.4 -3.3 -3.0 -2.7 -2.7 -2.8 -2.1
Leg fat percentage (right) 0.6 2.2 4.7 -1.3 -1.7 -1.3 -0.5 0.9 -1.1 -1.2 -1.6 -2.2 -1.8 -1.7 -1.6 -1.8 -1.4
Arm fat-free mass (right) 2.6 13.4 25.9 -4.6 -3.7 -3.8 -3.8 2.7 -4.0 -3.4 -1.9 -5.1 -4.3 -3.2 -3.6 -3.7 -1.9
Exposure to tobacco smoke outside home 4.0 5.3 8.0 2.2 2.4 2.5 2.0 -1.7 2.8 2.5 2.4 1.9 2.6 2.5 2.3 2.4 1.7
Comparative body size at age 10 0.7 1.9 7.2 -1.1 -1.5 -1.5 -1.7 0.9 -1.9 -1.1 -0.4 -2.7 -1.5 -0.9 -1.1 -1.2 0.0
Number of full brothers 0.1 0.2 0.5 -0.1 -0.0 -0.2 -0.2 0.2 0.6 -0.6 -0.2 -0.5 -0.5 -0.3 -0.4 -0.3 -0.7
Worry too long after embarrassment 2.2 3.7 8.3 -1.7 -2.1 -2.1 -1.4 2.7 -1.6 -1.9 -1.6 -1.0 -1.4 -1.9 -2.9 -2.7 -0.8
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.7 2.5 1.6 0.5 0.6 1.4 -0.2 0.9 0.5 0.9 1.0 0.9 0.8 0.5 0.4 0.2
Wheeze or whistling in the chest in last year 1.1 1.9 5.3 -1.0 -1.4 -1.2 -0.2 1.5 -0.0 -1.2 0.8 -2.3 -1.2 -1.4 -1.7 -1.8 -1.5
Number of children fathered 2.3 2.6 7.6 -2.8 -1.6 -1.6 -1.9 0.3 -1.4 -1.1 -2.3 -1.5 -1.9 -1.3 -1.2 -1.7 -0.4
Reason for reducing amount of alcohol drunk: Health precaution 2.8 3.2 7.4 -2.5 -1.7 -1.8 -1.6 1.6 -1.8 -1.8 -1.4 -2.7 -1.9 -1.4 -1.7 -1.7 -0.7
Age at first live birth 1.2 2.1 3.2 -1.6 -1.4 -1.5 -1.2 1.7 -1.7 -1.4 -1.8 -0.9 -1.3 -1.4 -1.7 -1.6 -0.8
Pulse wave peak to peak time 0.1 0.1 0.5 0.1 0.1 -0.1 0.1 0.5 0.2 -0.5 -0.6 0.2 -0.0 -0.4 -0.1 -0.2 -0.7
Health satisfaction 0.8 1.0 3.1 -0.2 1.0 1.3 0.3 0.5 1.4 0.8 0.8 1.8 1.5 0.9 0.1 0.4 1.0
Shortness of breath walking on level ground 2.4 2.8 6.9 -2.6 -2.0 -1.7 -1.9 1.0 -1.0 -1.5 -1.1 -2.2 -1.9 -1.4 -1.3 -1.6 -1.4
Qualifications: College or University degree 1.4 4.3 11.5 -1.0 -1.8 -1.5 -0.7 3.4 -2.7 -2.5 -2.5 -0.0 -1.2 -2.4 -2.9 -2.2 -1.3
Eye problems/disorders: None of the above 0.2 0.2 0.7 -0.2 0.2 -0.2 -0.8 -0.0 -0.7 0.2 0.8 -0.4 -0.2 0.1 0.4 0.1 -0.4
Mouth/teeth dental problems: Loose teeth 3.1 3.6 4.7 2.0 2.0 2.2 2.1 -1.7 1.8 1.8 1.5 2.0 2.0 1.9 1.5 2.0 2.0
Emphysema/chronic bronchitis 0.4 0.5 1.2 -0.3 -0.6 -0.4 -0.4 1.1 0.9 -0.8 1.0 -0.4 0.1 -0.6 -0.6 -0.7 -0.9
Medication for pain relief, constipation, heartburn 0.1 0.2 1.1 -1.1 0.1 -0.2 -0.0 0.2 -0.9 0.1 -0.0 0.3 0.1 0.0 -0.2 -0.1 0.3
Neck or shoulder pain in last month 0.9 1.3 3.9 -1.0 -1.0 -1.0 -0.8 0.6 -1.1 -1.4 -1.1 -0.8 -1.4 -1.5 -0.5 -0.9 -2.0
Medication: Blood pressure 0.2 0.3 0.8 -0.0 0.3 0.7 0.2 -0.9 0.6 0.6 0.0 0.4 0.6 0.7 0.8 0.4 0.2
Angina (self-reported) 1.9 2.5 8.4 -0.5 -2.0 -1.3 -1.5 1.1 -0.7 -1.9 -0.5 -1.6 -1.6 -1.6 -1.2 -1.9 -2.9
Migraine (self-reported) 0.7 0.9 3.2 0.7 1.1 1.2 1.8 -0.2 0.5 1.0 -0.3 1.0 1.0 0.7 0.5 0.9 0.8
Medication: Ibuprofen 0.3 0.4 1.2 0.6 0.7 1.1 0.0 0.8 0.9 0.2 -0.0 0.6 0.5 0.6 -0.3 0.3 0.8
Medication: Allopurinol 6.8 9.0 19.1 1.9 2.8 3.0 1.4 -3.8 2.3 3.0 2.6 3.6 3.0 3.1 4.4 3.8 1.4
Medication: Omeprazole 0.4 0.5 1.6 1.1 0.6 0.9 0.9 0.2 1.3 0.2 0.7 0.9 0.9 -0.0 -0.1 0.2 -0.3
Medication: Seretide 50 evohaler 2.1 2.4 5.4 -1.1 -1.9 -2.0 -1.4 1.1 -0.7 -1.4 -1.1 -2.3 -1.8 -1.5 -1.3 -1.8 -1.4
Mean time to correctly identify matches 3.5 6.6 12.1 1.8 2.9 2.8 3.5 -1.4 1.3 2.7 2.0 3.4 3.1 2.8 1.9 2.6 2.4
Heart disease (mother) 0.6 0.8 2.2 -1.5 -1.1 -1.1 -0.6 0.5 -0.4 -0.8 -1.3 -0.4 -0.5 -0.8 -0.4 -0.8 -1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.1 1.3 3.5 -1.9 -1.3 -1.2 -1.4 -0.1 -0.9 -0.7 -1.5 -1.3 -1.1 -0.8 -0.0 -1.0 -1.2
Whole body fat mass 2.5 10.4 19.0 -3.7 -3.4 -3.2 -2.5 2.5 -3.4 -3.1 -2.5 -4.4 -3.7 -3.1 -3.4 -3.5 -2.2
Leg fat mass (right) 2.2 8.6 16.7 -3.2 -3.1 -2.8 -2.1 2.3 -2.8 -2.8 -2.2 -4.1 -3.4 -2.9 -3.2 -3.3 -2.1
Arm predicted mass (right) 2.5 12.8 22.6 -4.5 -3.6 -3.7 -3.6 2.8 -3.9 -3.4 -2.0 -4.8 -4.0 -3.2 -3.6 -3.7 -1.9
Pulse rate, automated reading 0.4 1.2 5.2 -1.6 -0.6 -0.9 -0.4 1.1 -0.9 -0.9 -2.3 -0.6 -1.0 -0.9 -1.1 -1.1 -0.7
Alcohol intake frequency. 2.2 5.1 11.2 -1.0 -2.2 -1.9 -1.2 2.4 -1.4 -2.3 -1.5 -3.3 -2.8 -2.5 -3.0 -2.8 -1.5
Comparative height size at age 10 0.3 1.5 4.5 -1.9 -1.4 -1.7 -1.7 0.5 -2.1 -0.8 -1.0 -0.4 -0.7 -0.9 -0.9 -1.2 -0.4
Number of full sisters 0.8 1.0 2.3 -0.3 -1.1 -1.0 -0.9 0.9 0.8 -1.0 -0.4 -1.5 -1.0 -1.2 -0.9 -1.3 -1.0
Suffer from ‘nerves’ 0.3 0.5 1.0 -0.0 -0.7 -0.9 -0.1 0.6 -0.5 -0.4 -0.6 -1.0 -0.7 -0.8 -1.0 -1.0 -0.3
Overall health rating 1.4 3.1 6.7 1.9 1.6 2.3 1.3 -0.4 2.5 1.8 2.6 1.0 2.0 1.9 0.8 1.2 1.7
Chest pain or discomfort 1.7 2.4 4.3 -1.0 -1.9 -1.8 -1.4 1.6 -0.6 -1.5 -0.7 -1.3 -1.4 -1.6 -1.9 -2.1 -1.9
Had major operations 1.6 1.8 3.9 -1.1 -1.5 -1.3 -0.2 1.0 -1.3 -1.2 -1.2 -1.8 -1.4 -1.7 -2.0 -1.6 0.1
Age at last live birth 0.4 0.6 1.8 -1.4 -0.8 -0.7 -0.9 0.6 -0.6 -0.7 -1.0 -0.2 -0.4 -0.9 -0.6 -0.7 -0.7
Family relationship satisfaction 1.9 2.3 5.3 1.0 1.1 1.3 -0.9 -1.2 2.0 1.2 2.3 1.8 1.5 1.7 2.1 1.6 -0.1
Leg pain on walking 0.7 0.9 2.1 -0.2 0.8 1.0 1.4 -0.8 0.2 1.2 0.9 0.2 0.6 1.4 0.7 0.9 1.4
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.2 2.1 0.0 0.3 0.4 -0.1 0.2 1.4 -0.1 0.4 -0.5 0.1 0.1 -0.1 0.3 0.4
Commuting to job workplace: Car/motor vehicle 0.8 0.9 2.4 -0.7 -0.9 -0.8 0.1 1.2 0.3 -0.8 -1.5 -0.6 -0.2 -1.2 -1.1 -1.3 -1.0
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 2.2 -0.2 -0.4 -0.8 -0.4 -0.7 -1.5 -0.2 -1.0 -0.2 -0.6 -0.1 0.4 -0.1 -0.4
Medication: Aspirin 0.4 0.5 2.1 0.4 -1.1 -0.5 -0.9 -1.1 0.1 -0.2 -0.9 -0.1 -0.3 -0.2 0.7 -0.2 -1.4
Supplements: Vitamin C 1.2 1.4 3.1 1.2 1.2 0.9 1.0 -0.3 1.8 1.3 1.0 1.3 1.4 1.5 0.6 0.9 1.5
Knee pain experienced in last month 0.4 0.6 2.6 0.3 0.1 0.2 0.2 -1.1 1.6 -0.1 0.1 -1.1 -0.3 -0.0 1.3 0.7 -0.9
Hypertension (Self-reported) 2.9 8.1 12.5 2.1 3.1 3.5 2.5 -2.3 2.2 3.3 2.6 2.6 3.1 3.5 2.6 2.8 3.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.5 1.4 0.9 -0.8 -0.2 0.3 -0.1 0.8 -0.6 -1.2 -0.4 -0.5 -1.0 -0.3 -0.3 -0.9
Illnesses of father: Heart disease 2.4 3.3 6.7 -2.1 -1.6 -1.7 -1.8 1.8 -0.9 -2.2 -2.6 -0.6 -1.8 -1.9 -1.8 -1.8 -1.9
Illnesses of siblings: Diabetes 0.7 0.8 1.8 -1.0 -0.8 -0.8 -0.6 0.9 0.1 -1.1 -1.3 -0.8 -1.0 -1.0 -1.0 -1.0 -0.6
Smoking status: Previous 0.9 1.3 5.7 0.4 0.8 0.5 -0.2 -2.4 0.3 1.6 0.8 -0.5 0.1 1.5 1.7 1.3 1.2
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.2 3.2 -0.7 -0.8 -0.8 -1.7 1.8 -0.7 -1.7 0.3 -1.0 -0.8 -0.7 -1.1 -0.9 -1.0
Whole body fat-free mass 2.2 12.8 29.5 -4.8 -3.5 -3.6 -4.0 2.4 -3.9 -3.2 -1.3 -5.4 -4.2 -2.8 -3.5 -3.5 -1.3
Leg fat-free mass (right) 3.7 19.8 42.8 -5.8 -4.4 -4.5 -5.0 3.0 -5.0 -4.1 -1.9 -6.5 -5.3 -3.6 -4.3 -4.4 -1.9
Arm fat percentage (left) 2.3 9.2 18.3 -3.4 -3.1 -3.0 -2.2 2.1 -3.3 -2.9 -2.4 -4.3 -3.7 -3.0 -3.1 -3.2 -2.0
Average weekly red wine intake 0.4 0.6 3.5 -0.4 -0.6 -0.7 -0.0 0.5 -1.9 -0.7 -1.1 0.8 -0.3 -0.3 -0.7 -0.6 0.2
Handedness (chirality/laterality): Left-handed 0.1 0.2 0.5 -0.3 -0.4 -0.0 -0.7 -0.5 -0.4 -0.0 -0.0 0.6 -0.2 0.1 0.5 0.0 -0.6
Mood swings 6.7 12.0 19.5 -3.6 -3.2 -3.1 -2.5 4.4 -2.8 -3.9 -3.0 -3.0 -3.3 -3.9 -4.3 -4.1 -2.9
Loneliness, isolation 0.4 0.5 2.9 -0.3 -0.3 -0.5 -0.7 0.3 1.2 -0.7 0.3 -0.5 -0.3 -0.5 0.2 -0.5 -1.7
Long-standing illness, disability or infirmity 0.8 1.2 3.1 1.4 0.9 1.5 1.5 -0.1 1.8 0.9 1.1 1.2 1.4 0.9 0.6 0.6 0.3
Ever had bowel cancer screening 0.2 0.2 2.1 1.5 -0.3 -0.4 0.2 -0.5 -0.6 0.3 -0.2 0.1 -0.0 0.0 0.2 -0.1 -0.3
Diabetes diagnosed by doctor 1.0 1.6 2.6 -1.1 -1.5 -1.1 -0.1 0.7 -0.9 -1.2 -1.6 -1.4 -1.2 -1.6 -1.0 -1.5 -1.5
Ever had stillbirth, spontaneous miscarriage or termination 6.7 7.2 12.2 1.7 3.0 3.0 2.7 -2.0 1.6 3.3 1.6 3.5 3.2 3.0 2.2 2.6 3.0
Friendships satisfaction 1.6 2.0 4.3 1.1 1.1 1.7 -0.3 -1.1 2.1 1.4 1.7 1.9 1.5 1.6 1.6 1.1 0.1
Qualifications: nursing, teaching 3.5 5.4 8.5 -2.1 -2.3 -2.4 -2.9 2.1 -2.9 -2.3 -2.4 -1.7 -2.4 -2.2 -2.5 -2.5 -1.4
Commuting to job workplace: Walk 0.5 0.6 1.5 -0.6 -0.9 -1.0 -1.2 -1.0 -1.2 -0.1 -0.5 -0.5 -1.0 -0.1 0.5 -0.2 -0.2
Eye problems/disorders: Cataract 0.3 0.3 1.0 -0.5 -0.5 -0.1 -0.0 0.9 0.2 -0.4 -0.9 0.3 0.1 -0.6 -1.0 -0.8 -0.2
Mouth/teeth dental problems: Mouth ulcers 1.2 1.8 4.4 -0.7 -1.0 -1.4 -0.4 1.8 -0.6 -2.0 -1.3 -0.9 -1.3 -1.8 -1.2 -1.2 -2.1
Medication for cholesterol 0.4 0.6 3.3 -0.7 -0.4 -0.9 0.2 -0.1 -0.9 -0.5 -1.8 0.1 -0.5 -0.9 -0.2 -0.5 -0.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.0 1.1 2.7 -1.0 -1.6 -1.4 -1.4 0.6 -0.0 -0.8 -0.9 -1.3 -1.0 -1.0 -0.8 -1.2 -0.6
Back pain experienced in last month 0.3 0.4 1.6 1.1 -0.1 0.3 -0.0 -0.8 1.3 -0.2 0.1 0.4 0.1 -0.5 0.6 0.2 -1.2
Mineral and other dietary supplements 0.8 1.1 3.5 -1.1 -0.7 -0.8 -1.1 -0.2 -1.9 -0.8 -0.9 -1.7 -1.5 -0.8 -0.2 -0.4 -0.6
Breast cancer (self-reported) 3.1 3.7 6.2 -1.9 -1.9 -2.2 -2.4 1.4 -2.3 -2.3 -1.0 -1.8 -2.2 -1.7 -1.1 -1.6 -2.5
Asthma (self-reported) 2.0 3.9 6.8 -2.3 -2.1 -2.4 -1.3 2.0 -1.1 -2.0 -1.1 -2.6 -2.2 -1.7 -2.2 -2.3 -1.4
Osteoporosis (self-reported) 0.2 0.3 1.1 -1.1 -0.2 -0.1 -0.8 0.8 -0.3 -0.3 0.2 -0.3 -0.0 -0.6 -0.6 -0.5 -0.3
Osteoarthritis (self-reported) 0.5 0.7 1.4 0.5 0.9 1.0 0.4 -1.0 0.1 1.1 0.4 0.3 0.5 0.8 0.9 1.1 1.2
Medication: Aspirin 0.5 0.7 2.7 0.2 -1.2 -0.7 -1.1 -1.3 -0.2 -0.1 -0.8 -0.3 -0.4 -0.1 1.0 -0.2 -1.6
Medication: Gliclazide 2.5 2.9 7.6 -1.1 -2.0 -1.6 -0.5 1.0 -1.2 -2.0 -2.0 -1.6 -1.7 -2.1 -0.9 -1.8 -2.8
Illnesses of father: None of the above (group 1) 0.3 0.4 2.5 0.2 0.0 -0.2 -0.1 -0.1 0.5 0.2 1.6 -1.4 -0.2 0.0 -0.1 -0.0 0.5
Smoking status: Current 1.3 2.1 5.6 0.6 1.4 1.6 0.4 -0.8 2.0 1.7 1.7 0.8 1.8 1.6 0.8 1.1 2.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 6.7 14.2 21.7 2.3 4.2 3.8 2.5 -3.9 2.4 4.4 3.1 3.7 3.9 4.7 4.4 4.2 4.2
Whole body water mass 2.3 12.9 29.2 -4.8 -3.5 -3.7 -4.0 2.4 -4.0 -3.2 -1.4 -5.4 -4.2 -2.8 -3.4 -3.5 -1.3
Leg predicted mass (right) 3.8 20.5 43.2 -5.9 -4.4 -4.6 -5.1 3.1 -5.1 -4.2 -2.0 -6.6 -5.3 -3.7 -4.3 -4.5 -1.9
Arm fat mass (left) 2.9 11.9 23.9 -4.1 -3.6 -3.6 -2.9 2.3 -3.7 -3.2 -2.4 -4.9 -4.2 -3.3 -3.3 -3.5 -2.3
Number of self-reported non-cancer illnesses 0.3 0.5 1.6 0.6 0.4 1.0 0.8 0.2 1.3 0.8 0.2 1.0 1.0 0.8 -0.1 -0.1 0.7
Average weekly champagne plus white wine intake 0.1 0.2 1.0 0.3 0.3 -0.3 0.9 -0.1 0.2 0.4 0.1 -0.3 0.1 0.5 0.0 0.3 1.0
Miserableness 11.4 19.7 33.5 -4.4 -4.4 -3.8 -3.1 5.6 -3.6 -5.0 -4.2 -3.4 -3.9 -4.9 -5.8 -5.5 -3.6
Guilty feelings 2.9 4.4 7.1 -1.4 -2.4 -2.3 -0.9 2.3 -2.3 -2.4 -1.6 -1.3 -2.0 -2.7 -2.4 -2.4 -2.1
Wears glasses or contact lenses 3.2 3.7 8.2 -1.0 -2.0 -2.1 -0.9 2.9 -1.0 -2.2 -1.3 -1.6 -1.7 -1.9 -2.8 -2.6 -1.2
Ever taken oral contraceptive pill 0.6 0.7 1.9 0.4 0.8 0.5 1.2 -0.7 0.5 1.0 0.7 0.2 0.8 0.8 0.5 0.9 1.4
Hearing aid user 0.8 0.9 2.8 0.1 -1.2 -0.7 -1.7 0.4 -0.4 -0.9 -0.5 -1.4 -1.2 -0.5 -0.8 -1.2 -0.6
Mother’s age at death 1.2 1.5 3.8 -0.3 -1.6 -1.6 -1.8 -0.6 -1.2 -0.9 -1.2 -1.2 -1.2 -1.0 0.1 -1.0 -1.9
Financial situation satisfaction 0.3 0.3 1.9 -1.1 -0.1 -0.2 -1.4 -0.4 0.7 -0.0 0.5 -0.5 -0.3 -0.1 0.4 0.2 -0.1
Tinnitus: Yes, now most or all of the time 0.2 0.2 0.7 0.9 0.1 0.6 0.4 0.2 0.5 0.3 0.7 -0.3 0.2 0.2 -0.0 0.2 0.7
Commuting to job workplace: Public transport 1.6 1.9 4.8 0.7 1.8 1.9 1.3 -0.1 -0.2 1.1 1.4 1.6 1.3 1.4 0.4 1.6 2.2
Eye problems/disorders: Glaucoma 0.8 0.9 5.0 -1.8 -0.7 -0.3 -0.7 0.3 -0.8 -0.4 -2.2 0.2 -0.5 -0.4 -0.9 -0.8 0.8
Medication: Blood pressure 3.0 5.7 13.7 2.8 2.4 2.7 2.0 -1.0 2.5 2.3 3.7 2.4 2.8 2.4 1.7 2.0 1.8
Pain type(s) experienced in last month: Hip pain 1.9 2.4 4.8 1.6 2.1 2.2 2.1 -0.1 1.9 1.1 1.0 1.6 1.8 1.3 1.2 1.6 1.0
Supplements: Fish oil (including cod liver oil) 0.2 0.2 0.9 0.6 -0.0 0.1 0.4 0.0 0.8 0.0 0.2 1.0 0.6 0.1 0.5 0.2 -0.6
High cholesterol (Self-reported) 0.4 0.7 1.9 0.7 -1.0 -0.7 -0.1 0.2 -0.7 -0.9 -1.4 -0.2 -0.7 -1.0 -0.3 -0.7 -1.4
Medication: Bendroflumethiazide 0.6 1.0 2.2 1.0 1.1 1.2 1.0 -0.2 1.5 0.7 0.8 1.1 1.1 0.8 0.9 1.1 0.4
Medication: Paracetamol 0.3 0.4 1.0 1.0 0.7 0.9 0.5 -0.5 0.3 0.6 0.6 0.5 0.6 0.6 0.5 0.7 0.7
Medication: Lisinopril 0.4 0.5 2.3 0.8 0.2 0.4 1.5 -0.6 0.6 0.6 1.4 0.1 0.6 0.5 0.5 0.5 0.2
Medication: Atorvastatin 0.1 0.1 0.6 -0.5 0.2 0.5 -0.2 0.3 0.7 0.0 0.5 0.1 0.4 0.4 0.2 0.3 0.3
Illnesses of father: High blood pressure 0.4 0.5 1.5 -1.1 -0.3 -0.2 -0.7 0.8 -0.5 -0.9 -1.2 0.2 -0.3 -0.6 -0.3 -0.3 -0.9
Alcohol drinker status: Never 4.3 5.2 10.2 -1.4 -2.2 -1.6 -1.1 3.1 -2.4 -2.5 -2.4 -2.2 -2.2 -2.4 -3.2 -2.7 -1.3
Ever smoked 2.4 4.2 8.4 1.5 1.6 1.7 0.3 -2.6 2.2 2.2 2.9 0.5 1.6 2.6 2.4 2.4 2.1
Basal metabolic rate 2.6 14.6 32.8 -5.0 -3.8 -4.0 -4.2 2.6 -4.1 -3.4 -1.6 -5.7 -4.5 -3.1 -3.6 -3.8 -1.7
Leg fat percentage (left) 0.8 2.7 6.0 -1.6 -1.9 -1.6 -0.8 0.8 -1.5 -1.3 -1.5 -2.5 -2.0 -1.8 -1.7 -1.9 -1.4
Arm fat-free mass (left) 2.4 12.1 26.0 -4.5 -3.5 -3.8 -3.7 2.2 -3.6 -3.2 -1.6 -5.1 -4.2 -3.0 -3.2 -3.4 -1.8
Number of operations (self-reported) 4.0 6.0 10.1 -2.5 -2.7 -2.3 -1.6 2.1 -1.3 -2.5 -2.4 -3.2 -2.8 -2.9 -3.0 -2.8 -1.1
Average weekly beer plus cider intake 4.7 6.8 9.7 1.1 3.0 3.1 0.7 -2.6 3.0 2.9 2.2 2.5 2.9 3.1 3.0 2.9 2.2
Irritability 1.1 1.9 7.8 -1.4 -0.6 -0.6 -0.6 2.8 -0.7 -1.3 -1.2 -0.9 -1.1 -1.2 -2.3 -1.7 -0.1
Risk taking 4.7 6.9 11.5 -2.2 -2.8 -3.0 -0.8 2.4 -2.2 -3.3 -2.8 -1.6 -2.7 -3.4 -2.5 -2.8 -3.2
Ever had prostate specific antigen (PSA) test 0.6 0.7 1.6 -0.6 -1.1 -0.8 -1.0 1.0 -0.3 -1.1 -0.5 -1.3 -1.0 -0.6 -0.9 -0.9 -0.4
Fractured/broken bones in last 5 years 4.5 5.8 13.0 -1.1 -2.4 -1.9 -2.0 3.6 -1.5 -2.6 -1.6 -2.4 -2.3 -2.6 -3.4 -3.1 -1.8
Age started oral contraceptive pill 1.9 2.4 4.1 -1.2 -1.7 -1.1 -0.8 1.9 -2.0 -1.9 -1.5 -0.4 -1.1 -1.6 -1.9 -1.9 -1.5
Diastolic blood pressure, automated reading 1.4 4.2 12.0 0.5 2.6 2.3 1.1 -1.6 1.3 2.4 1.7 1.3 1.8 2.7 1.7 2.4 3.5
Ever depressed for a whole week 1.1 1.3 2.4 -1.5 -1.2 -1.0 -0.7 0.6 -1.3 -1.1 -1.1 -0.4 -1.1 -1.4 -1.4 -1.6 -1.0
Unable to work because of sickness or disability 0.3 0.4 1.0 -0.5 -0.8 -0.6 -1.0 -0.6 -0.5 -0.3 -0.4 -0.8 -0.6 -0.3 0.2 -0.2 -0.9
Commuting to job workplace: Cycle 8.2 9.9 16.9 -3.2 -3.7 -3.6 -4.1 1.3 -2.8 -3.1 -2.6 -4.0 -3.8 -2.9 -2.2 -3.0 -2.5
Myopia 1.5 2.2 5.0 -1.3 -1.4 -1.6 -0.8 2.2 -1.6 -1.4 -0.3 -1.4 -1.3 -1.5 -2.1 -1.9 -0.5
Vascular/heart problems diagnosed by doctor 1.7 4.7 8.0 -1.7 -2.3 -2.7 -1.9 1.6 -1.4 -2.6 -2.1 -1.9 -2.4 -2.8 -1.7 -2.0 -2.6
Cholesterol lowering medication 1.0 1.5 2.3 -0.3 -1.4 -1.2 -1.0 0.7 -1.5 -1.1 -1.2 -1.2 -1.5 -1.4 -1.1 -1.4 -1.2
Medication: Omeprazole (e.g. Zanprol) 0.6 0.7 2.4 1.2 0.8 1.2 0.6 -0.6 1.6 0.5 0.4 1.1 1.0 0.3 0.6 0.7 -0.3
Pain experienced in last month 0.3 0.6 4.2 -0.9 -0.3 -0.5 -0.7 0.2 -2.0 0.2 0.6 -0.2 -0.3 0.5 -0.5 -0.3 1.0
Supplements: Calcium 0.6 0.6 2.5 0.1 -0.6 -0.4 0.2 1.6 0.4 -0.8 -0.5 -0.8 -0.4 -0.8 -1.5 -1.0 -0.2
Basal cell carcinoma (self-reported) 0.9 1.0 2.4 1.0 1.1 1.1 1.6 -0.9 0.1 1.1 0.7 1.0 1.0 1.0 0.7 1.2 1.0
Heart attack/myocardial infarction (self-reported) 0.5 0.7 1.6 -0.9 -1.1 -0.7 -1.1 0.8 0.1 -1.2 -0.8 -0.6 -0.6 -0.7 -0.4 -0.6 -1.2
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 2.1 0.0 -0.4 0.1 -0.3 0.5 -0.3 -0.6 -1.5 0.4 -0.4 -0.6 -0.2 -0.6 -1.4
Heart disease (siblings) 1.2 1.4 4.0 -0.5 -0.7 -0.9 -0.1 1.9 -0.2 -1.5 -0.4 -1.5 -1.0 -1.4 -2.0 -1.5 -1.0
Alcohol drinker status: Previous 0.4 0.5 3.4 0.8 -0.4 -0.4 -0.6 -0.2 -0.7 0.2 0.6 -1.9 -0.8 0.1 -0.3 -0.5 0.5
Pack years of smoking 0.4 0.6 2.4 -0.1 -1.1 -0.9 -0.2 0.3 -0.0 -0.7 -0.1 -1.6 -0.7 -0.8 -0.9 -1.0 -0.6
Impedance of whole body 1.2 5.9 19.4 3.2 2.5 2.2 2.9 -0.9 2.6 1.9 0.3 4.4 3.2 1.8 1.9 2.3 0.8
Leg fat mass (left) 2.4 9.5 18.7 -3.4 -3.3 -3.0 -2.3 2.3 -3.1 -2.9 -2.2 -4.3 -3.6 -3.0 -3.3 -3.4 -2.2
Arm predicted mass (left) 2.3 11.5 24.7 -4.4 -3.4 -3.6 -3.6 2.3 -3.5 -3.2 -1.4 -5.0 -4.1 -2.9 -3.2 -3.4 -1.8