Hub : Genes

PIGL

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.0880	0.0470	1.0e-03	0.030	NA	0.044	NA	0.044	8.7e-03	NA	1.9e-03	NA	1.8e-03
2	GTEx	Artery Tibial	0.0807	0.0336	2.2e-05	0.098	NA	0.060	NA	0.076	4.0e-08	NA	1.9e-05	NA	1.5e-06
3	GTEx	Cells Transformed fibroblasts	0.0360	0.0190	5.6e-03	0.023	NA	0.018	NA	0.001	6.7e-03	NA	1.5e-02	NA	2.4e-01
4	GTEx	Skin Sun Exposed Lower leg	0.1120	0.0570	1.6e-03	0.018	NA	0.025	NA	0.014	1.2e-02	NA	3.3e-03	NA	2.2e-02
5	GTEx	Testis	0.1980	0.0800	1.7e-04	0.064	NA	0.103	NA	-0.001	8.7e-04	NA	2.6e-05	NA	3.7e-01
6	GTEx	Whole Blood	0.0310	0.0160	2.1e-03	0.022	NA	0.025	NA	0.020	3.4e-03	NA	2.2e-03	NA	5.4e-03
7	METSIM	Adipose	0.1608	0.0534	6.4e-06	0.058	0.030	0.048	0.050	0.054	4.3e-09	2.2e-05	9.1e-08	4.4e-08	1.5e-08
8	ROSMAP	Brain Pre-frontal Cortex	0.0548	0.0255	2.8e-05	0.022	0.037	0.009	0.032	0.013	6.2e-04	1.2e-05	2.2e-02	5.0e-05	6.9e-03
9	YFS	Blood	0.0173	0.0082	1.6e-05	0.021	0.017	0.014	0.017	0.017	1.1e-07	1.5e-06	1.4e-05	1.8e-06	2.2e-06
10	TCGA	Breast Invasive Carcinoma	0.0205	0.0136	2.3e-04	0.012	0.015	0.006	NA	0.009	1.1e-03	3.5e-04	1.9e-02	NA	5.2e-03
11	TCGA	Kidney Renal Clear Cell Carcinoma	0.0578	0.0274	6.7e-08	0.064	0.074	0.071	NA	0.070	1.1e-07	1.1e-08	2.1e-08	NA	2.5e-08
12	TCGA	Brain Lower Grade Glioma	0.0322	0.0203	9.9e-04	0.028	0.011	-0.002	NA	0.009	3.6e-04	1.9e-02	7.1e-01	NA	2.8e-02
13	TCGA	Pheochromocytoma and Paraganglioma	0.2620	0.1020	1.9e-05	0.128	0.044	0.058	NA	0.034	9.0e-06	7.4e-03	2.5e-03	NA	1.7e-02
14	TCGA	Thyroid Carcinoma	0.0680	0.0380	2.0e-03	0.022	0.026	0.005	NA	0.013	3.1e-03	1.3e-03	1.0e-01	NA	1.7e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Bipolar Disorder (2018)	0.4	0.6	1.7	0.7	1.0	0.5	1.1	-0.7	0.6	0.7	-0.1	1.3	0.7	0.6	0.9	1.1	0.3
Bipolar Disorder or Schizophrenia	0.2	0.5	1.8	0.6	0.8	1.0	0.2	-0.6	0.3	0.6	0.2	1.3	0.7	0.8	1.0	0.8	-0.1
Depressed Affect (Nagel 2018)	7.1	14.9	20.7	-3.7	-3.9	-3.9	-2.9	3.7	-3.5	-4.0	-3.8	-3.4	-3.9	-4.5	-4.2	-4.5	-3.7
Depression (Nagel 2018)	2.5	3.8	9.5	-1.3	-2.4	-2.1	-2.6	0.2	-1.4	-1.6	-1.3	-2.1	-2.2	-2.0	-0.7	-2.0	-3.1
Intelligence (Savage-Jansen 2018)	1.8	5.6	11.7	-2.2	-2.2	-2.6	-2.0	2.7	-2.3	-2.6	-3.4	-1.6	-2.1	-2.5	-2.6	-2.5	-1.2
Neuroticism (Nagel 2018)	3.2	7.6	10.8	-2.1	-2.9	-3.2	-1.8	2.3	-2.8	-2.8	-2.6	-2.5	-2.9	-3.3	-2.8	-3.1	-3.0
Schizophrenia (2018)	0.1	0.2	0.7	0.2	0.3	0.8	-0.6	-0.2	0.0	0.2	0.3	0.7	0.4	0.5	0.5	0.1	-0.4
Schizophrenia vs Biploar Disorder	1.1	1.4	3.6	0.8	1.1	1.6	0.5	-1.2	0.9	1.2	0.5	1.9	1.3	1.5	1.3	1.1	1.0
Worry (Nagel 2018)	0.1	0.2	1.0	0.2	-0.1	-0.7	0.7	-0.5	-1.0	0.1	-0.2	0.0	-0.3	-0.3	0.2	-0.0	-0.6
Alzheimer’s Disease (in mother)	1.6	1.9	3.8	-0.6	-1.6	-1.2	-1.0	1.7	-1.5	-1.8	-0.9	-0.8	-1.3	-1.4	-1.4	-1.4	-1.9
Alzheimer’s Disease (in father)	2.1	2.3	4.4	1.2	1.8	1.9	0.9	-1.6	0.7	1.7	1.2	1.6	1.4	1.7	2.1	1.8	0.5
Alzheimer’s Disease (including proxy)	0.2	0.3	0.7	0.0	0.4	0.7	-0.1	-0.3	-0.9	0.3	0.5	0.7	0.3	0.5	0.7	0.6	-0.5
Crohns Disease (2017)	0.2	0.4	1.1	0.6	0.5	-0.0	1.0	-0.9	0.5	0.3	1.1	-0.4	0.1	0.5	0.5	0.9	0.8
Irritable Bowel Disease (IBD)	0.1	0.2	0.7	0.3	-0.2	-0.8	0.7	-0.8	-0.3	-0.1	0.3	-0.7	-0.7	-0.3	0.1	0.2	-0.1
Ulcerative Colitis (UC)	0.1	0.2	1.2	0.2	-0.3	-0.7	0.6	-1.1	-0.3	0.2	-0.1	-0.4	-0.6	-0.2	0.3	-0.0	-0.3
Major Depression (MDD)	0.7	0.9	4.1	-1.4	-0.7	-1.0	-0.3	0.8	-2.0	0.1	-1.5	-0.3	-0.7	-0.3	-0.6	-0.7	0.3
Reaction Time	6.1	11.6	16.2	2.9	3.9	3.8	3.9	-2.0	2.5	3.8	2.7	4.0	4.0	3.8	2.6	3.5	3.5
Verbal and Numeric Reasoning (VNR)	2.3	5.4	12.9	-2.1	-2.4	-2.7	-1.7	1.9	-2.7	-2.3	-3.6	-1.6	-2.4	-2.4	-2.1	-2.3	-1.3
Breast Cancer	0.1	0.3	1.4	0.5	0.2	0.3	0.3	-1.2	-0.4	0.6	0.4	-0.2	0.3	0.3	0.3	0.4	0.9
Ovarian Cancer	0.3	0.4	1.1	1.1	0.3	0.5	-0.3	-0.3	-0.6	0.4	1.1	0.4	0.2	1.1	0.6	0.5	0.3
Prostate Cancer	2.9	4.1	10.0	-0.6	-2.6	-2.1	-2.2	1.9	-1.5	-2.4	-1.9	-1.2	-1.7	-2.4	-1.4	-1.9	-3.2
Age at First Birth	1.9	2.7	7.5	-2.2	-1.7	-1.8	-1.9	-0.3	-2.7	-1.2	-2.0	-1.4	-1.9	-1.3	-0.6	-1.1	-1.1
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	1.4	2.0	4.3	-0.9	-1.4	-1.2	-1.8	1.4	-1.0	-1.5	-0.8	-2.1	-1.8	-1.3	-1.2	-1.3	-1.4
Coronary Artery Disease (CAD)	0.3	0.3	1.3	-0.3	0.9	0.5	0.8	1.1	0.5	0.1	1.0	-0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.1	0.1	0.5	0.1	0.6	0.3	0.2	-0.2	0.1	0.2	0.7	-0.6	0.0	0.3	0.2	0.4	0.3
Mean Putamen Volume	0.1	0.1	0.4	-0.1	0.1	0.2	-0.2	-0.1	-0.5	0.1	-0.6	0.1	-0.4	0.1	0.2	0.0	-0.0
Fasting Glucose	0.3	0.4	2.1	1.3	0.2	0.5	0.4	0.7	0.2	0.1	0.3	0.7	0.4	-0.3	0.1	-0.1	-1.5
HbA1C	0.7	0.7	2.9	1.0	0.7	0.8	1.2	-0.6	1.7	0.6	0.8	0.2	0.7	0.7	0.6	0.7	0.6
HDL Cholesterol	0.2	0.3	2.5	-1.6	0.0	0.1	-0.9	-0.4	-0.4	0.2	-1.0	0.3	0.1	0.1	0.1	0.1	0.4
LDL Cholesterol	0.3	0.4	1.1	-0.1	-0.5	-0.6	-0.0	0.5	0.1	-0.7	-1.0	-0.9	-0.8	-0.8	-0.5	-0.6	-0.9
Lupus	2.0	3.1	5.8	1.5	1.7	1.2	2.0	-2.4	1.5	1.8	1.5	1.3	1.4	1.7	2.4	2.3	1.3
Neuroticism (2016)	2.8	4.1	7.6	-1.6	-1.8	-2.0	-0.6	2.8	-0.9	-2.2	-2.3	-1.9	-1.8	-2.5	-2.6	-2.5	-1.6
Primary Biliary Cirrhosis	0.3	0.5	1.9	-1.4	-0.5	-0.6	0.3	0.9	-0.8	-0.3	-0.4	-0.7	-0.7	-0.6	-0.7	-0.6	-0.2
Rheumatoid Arthritis	4.3	5.9	11.1	2.1	2.0	2.3	1.9	-2.6	1.8	2.7	2.6	1.8	2.5	3.3	2.7	2.6	2.5
Schizophrenia (2014)	0.1	0.3	0.9	0.4	0.7	0.8	-0.3	-0.1	-0.1	0.4	0.3	0.9	0.8	0.8	0.3	0.2	0.5
Triglycerides	0.1	0.2	0.8	-0.0	0.1	0.1	0.6	-0.4	0.6	0.2	0.9	0.3	0.3	0.2	0.6	0.5	-0.1
Type 2 Diabetes (T2D) (2012)	1.4	1.6	8.3	-1.4	-1.2	-1.3	-1.4	2.9	-1.2	-1.7	-0.9	-1.4	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.2	0.4	0.8	0.1	-0.8	-0.9	-0.2	0.1	-0.6	-0.3	-0.2	-0.8	-0.6	-0.9	-0.5	-0.8	-0.7
Blood Eosinophil Count	0.7	5.2	14.1	1.3	2.5	2.5	1.2	-1.7	1.0	2.7	2.7	1.7	2.3	3.1	1.4	2.3	3.8
Blood Platelet Count	0.9	10.1	14.7	3.5	3.0	3.0	3.8	-2.3	3.5	3.0	3.4	2.9	3.1	3.5	2.8	3.4	2.8
Blood Red Count	0.1	0.6	1.5	1.2	-0.6	-0.9	-0.8	-0.8	-1.2	-0.4	0.0	-1.0	-1.0	-0.3	0.2	-0.1	-0.5
Blood White Count	10.2	75.9	98.8	7.8	8.8	8.5	6.5	-9.2	8.8	9.3	9.1	7.6	8.7	9.6	9.6	9.9	7.9
Heel T-Score	0.1	0.5	3.1	-1.3	-0.5	0.1	-1.8	-0.2	-1.0	-0.4	-0.0	-0.4	-0.2	0.0	0.3	0.0	0.0
BMI	3.0	17.3	48.4	-4.1	-4.5	-4.6	-3.2	2.2	-4.3	-3.8	-2.3	-7.0	-5.4	-3.9	-3.8	-4.1	-2.6
Height	0.2	4.7	8.5	-2.9	-2.4	-2.5	-2.9	1.7	-1.8	-2.4	-1.5	-2.3	-1.9	-1.8	-2.1	-2.4	-0.9
Waist Hip Ratio (WHR)	2.7	12.2	24.0	3.1	3.6	3.8	4.2	-2.3	4.2	3.3	2.3	4.9	4.1	3.1	3.2	3.5	1.9
Systolic Blood Pressure	1.7	8.3	13.5	2.1	3.4	3.5	2.2	-1.4	1.9	3.0	3.3	2.7	3.5	3.3	2.2	2.9	3.7
Smoking Status	1.8	4.4	12.6	0.7	1.9	1.8	0.7	-2.3	2.0	2.7	2.4	0.5	1.9	2.6	1.7	2.2	3.5
Allergy or Eczema	0.5	1.4	3.1	-0.4	-1.3	-1.3	-1.0	1.5	-1.0	-1.3	-0.4	-1.1	-1.2	-1.1	-1.8	-1.5	-0.6
Cardiovascular Disease	1.8	5.8	9.8	2.4	2.7	2.6	2.5	-2.8	1.1	3.1	1.7	1.6	2.2	2.8	2.5	2.5	2.3
Hypothyroidism (self reported)	0.6	1.3	3.6	0.6	1.0	0.8	0.5	-1.9	1.4	1.4	0.8	0.4	0.8	1.3	1.7	1.2	0.7
Respiratory disease	0.8	1.7	3.6	-1.4	-1.3	-1.6	-0.5	1.6	-0.8	-1.0	-0.5	-1.6	-1.1	-1.3	-1.9	-1.9	-0.5
Type 2 Diabetes (T2D) (2018)	0.4	0.8	1.7	-0.8	-1.0	-0.5	0.4	0.3	-0.8	-0.7	-1.3	-1.0	-0.9	-1.1	-0.6	-1.2	-1.3
Lung FEV1/FVC ratio	0.1	0.3	1.9	-0.8	0.2	0.0	-0.2	-0.7	-0.3	0.5	-1.4	0.4	-0.0	-0.1	0.6	0.1	-0.4
Lung FVC	4.3	21.8	28.0	4.0	5.2	4.9	3.9	-3.6	4.0	4.7	4.9	4.9	5.3	5.1	4.5	5.2	4.7
Neuroticism	2.5	6.0	10.0	-2.2	-2.4	-2.5	-0.6	2.5	-3.2	-2.1	-3.2	-1.3	-2.3	-2.7	-3.0	-3.0	-1.8
Chronotype (morning person)	1.3	3.1	10.7	-1.8	-1.7	-1.6	-2.5	0.7	-0.8	-1.7	-1.2	-3.3	-2.5	-1.4	-1.3	-1.5	-0.8
Hair Pigment	0.2	4.7	11.2	-1.6	-3.1	-2.3	-3.3	1.1	-0.6	-2.5	-1.4	-2.4	-2.6	-2.1	-1.7	-2.2	-1.9
Tanning	0.2	2.5	4.6	0.8	2.0	1.7	1.7	-1.1	0.9	1.8	0.5	2.1	2.1	1.5	1.4	1.9	1.6
Hand grip strength (left)	0.4	1.0	2.3	-0.2	1.2	1.0	-0.3	-0.9	0.7	1.1	0.1	1.2	1.2	1.2	1.0	1.1	1.5
Number of treatments/medications taken	0.5	0.8	2.1	0.8	0.6	1.3	0.7	0.5	1.4	0.7	0.7	1.1	1.4	0.9	-0.0	0.3	1.1
Average weekly spirits intake	0.4	0.5	2.1	-1.5	-0.1	-0.4	-1.3	-0.4	-0.9	0.2	-0.2	-0.8	-0.5	0.4	0.0	-0.1	1.0
Sensitivity / hurt feelings	0.2	0.4	1.2	-0.2	-0.6	-0.6	0.1	1.0	-0.7	-0.8	-0.4	-0.1	-0.3	-0.7	-0.6	-0.8	-1.1
Frequency of depressed mood in last 2 weeks	2.7	3.7	8.9	-1.2	-2.1	-2.0	-2.5	1.8	-0.3	-2.3	-0.9	-1.7	-1.9	-2.1	-1.5	-2.2	-3.0
Hearing difficulty/problems: Yes	1.6	2.4	4.9	0.7	1.4	1.8	1.3	-1.6	1.6	2.1	1.2	2.2	1.9	1.3	1.2	1.2	1.7
Relative age of first facial hair	0.2	0.5	3.3	0.6	0.7	0.9	0.2	0.1	0.3	0.2	0.3	1.8	0.6	0.8	0.3	0.7	0.4
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.8	0.5	0.3	0.6	0.5	0.3	0.9	0.2	0.8	0.8	0.7	0.2	-0.0	0.2	0.4
Ever used hormone-replacement therapy (HRT)	2.4	3.1	5.2	-1.1	-1.8	-1.3	-2.1	1.4	-2.3	-1.9	-1.7	-1.9	-1.9	-1.6	-1.3	-1.7	-2.0
Ever had hysterectomy (womb removed)	0.3	0.3	1.4	-0.1	0.4	0.9	0.5	0.4	1.2	0.4	-0.0	0.4	0.5	0.5	0.5	0.4	-0.5
Systolic blood pressure, automated reading	0.2	0.5	1.5	-1.1	-0.5	-0.2	-0.7	0.8	-0.6	-0.3	0.2	-1.2	-0.5	-0.2	-0.9	-0.7	0.7
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.8	0.2	0.3	0.2	0.4	0.1	0.8	-0.2	0.9	-0.1	0.2	0.0	0.4	0.1	-0.5
Angina	2.4	3.2	9.2	-0.7	-2.2	-1.6	-1.8	1.3	-0.8	-2.1	-0.8	-1.9	-1.9	-1.9	-1.4	-2.2	-3.0
Medication for hormone replacement therapy	0.4	0.4	1.6	-1.0	-0.2	0.1	-1.3	1.0	0.0	-0.8	0.3	-0.9	-0.5	-0.1	-0.2	0.0	-0.4
Vitamin and mineral supplements	0.4	0.5	2.6	-0.5	0.2	0.1	-0.8	-1.6	-0.3	0.3	-1.1	-0.3	-0.8	0.3	1.0	0.8	0.2
Supplements: Zinc	0.7	0.7	2.3	0.7	0.7	0.5	0.3	-0.7	1.1	1.0	0.2	0.7	0.8	1.2	0.7	0.9	1.5
Medication: Co-codamol	0.2	0.3	1.2	-0.4	0.4	0.7	-0.2	0.3	0.7	0.2	0.2	-0.5	0.2	0.3	-0.7	-0.0	1.1
Medication: Metformin	0.1	0.2	0.7	-0.3	-0.4	0.2	0.3	0.4	0.8	-0.3	0.1	-0.3	-0.1	-0.2	-0.2	-0.5	-0.8
Diabetes (father)	0.9	1.2	4.6	-0.4	-1.3	-1.3	0.0	-0.4	-0.4	-0.8	-1.8	-0.7	-1.0	-1.3	0.3	-0.6	-2.2
Diabetes (mother)	0.3	0.4	1.5	0.4	0.7	0.5	0.8	0.5	0.5	0.5	0.2	0.3	0.7	0.6	-0.2	0.3	1.2
Severe depression (siblings)	0.2	0.2	1.0	-1.0	-0.3	-0.0	-0.7	0.6	0.2	-0.6	-0.1	0.1	-0.1	-0.1	-0.1	-0.1	-0.5
Pack years adult smoking proportion	0.2	0.3	1.2	-0.1	-0.8	-0.7	-0.1	0.3	0.1	-0.5	0.2	-1.1	-0.4	-0.7	-0.7	-0.8	-0.5
Impedance of leg (right)	2.8	13.8	35.2	4.9	3.8	3.4	4.3	-2.0	4.5	3.2	1.2	5.9	4.6	2.9	3.2	3.5	1.3
Leg fat-free mass (left)	3.6	18.9	41.2	-5.7	-4.3	-4.4	-4.8	3.1	-4.8	-4.0	-2.0	-6.4	-5.1	-3.5	-4.2	-4.3	-1.8
Trunk fat percentage	1.9	7.6	11.3	-2.9	-2.9	-2.9	-1.9	2.0	-2.8	-2.7	-2.7	-3.4	-3.2	-2.8	-2.8	-2.9	-2.2
Hand grip strength (right)	0.9	2.5	6.2	0.7	2.1	1.7	0.6	-0.9	1.2	1.8	1.1	1.5	2.0	2.0	1.2	1.6	2.5
Townsend deprivation index at recruitment	4.6	6.4	8.9	2.4	2.9	2.6	2.8	-2.8	1.9	3.0	2.2	2.4	2.5	2.5	2.6	2.8	1.9
Current tobacco smoking	1.6	2.6	7.3	0.4	1.6	1.9	0.4	-0.9	2.2	1.9	1.9	0.8	2.0	1.8	0.9	1.4	2.7
Average weekly fortified wine intake	0.3	0.3	2.1	-1.5	-0.0	0.1	-1.1	-0.1	-0.5	0.3	-0.1	0.5	0.3	-0.0	-0.0	-0.1	0.3
Maternal smoking around birth	0.3	0.5	1.4	0.7	0.7	1.0	1.0	0.1	1.2	0.1	1.1	0.4	0.6	0.1	0.2	0.6	0.5
Fed-up feelings	1.6	2.9	6.1	-1.6	-1.6	-1.0	-1.6	2.4	0.1	-1.6	-2.0	-1.0	-1.2	-1.9	-2.3	-2.5	-1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.3	1.5	-0.2	-0.6	-0.2	-1.1	0.3	0.4	-0.2	-0.1	-0.6	-0.4	-0.3	-0.2	-0.8	-1.2
Relative age voice broke	0.8	1.2	2.4	1.1	1.1	1.4	1.2	-0.2	0.8	0.7	0.8	1.5	1.3	1.2	0.6	1.3	1.2
Taking other prescription medications	0.3	0.5	1.5	0.4	0.2	1.1	0.4	0.6	1.2	0.3	1.0	0.3	1.1	0.5	-0.5	0.0	1.0
Age when periods started (menarche)	2.1	5.1	7.9	2.4	2.3	2.2	1.8	-2.2	1.1	2.8	1.5	2.8	2.6	2.5	2.0	2.2	2.5
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.1	-0.8	-0.9	-0.1	-1.2	0.8	-1.3	-0.6	-1.4	-0.6	-0.8	-0.4	-0.6	-0.7	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	1.7	-0.9	-0.5	-0.6	-1.0	-0.4	-1.3	-0.7	-1.0	-0.2	-0.8	-0.2	0.4	0.2	-0.4
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	2.9	-1.2	-0.5	-1.4	0.3	-0.2	-0.6	-0.5	-1.0	-1.7	-0.9	-1.0	-0.3	-0.5	-0.6
Qualifications: CSEs or equivalent	1.0	1.3	5.2	-1.2	-0.1	-0.5	-1.8	-1.9	0.1	0.1	0.4	-0.4	-0.7	0.4	2.3	1.1	-1.5
Serious illness, injury or assault to yourself	0.5	0.6	1.3	0.6	0.8	1.1	0.4	-0.3	1.1	0.7	0.6	1.2	1.0	0.7	0.3	0.6	0.8
High blood pressure	3.8	10.5	16.2	2.6	3.6	3.8	2.7	-2.7	2.3	3.9	2.9	3.0	3.5	4.0	2.9	3.2	3.6
Hayfever, allergic rhinitis or eczema	2.0	4.3	7.4	-1.6	-2.2	-2.1	-2.1	2.6	-1.6	-2.5	-0.5	-2.2	-2.1	-1.9	-2.7	-2.4	-1.5
Multivitamins +/- minerals	0.7	0.9	3.2	-0.1	-1.0	-0.8	-0.2	1.8	-0.0	-1.3	0.1	-0.3	-0.2	-1.1	-1.1	-1.1	-1.4
Stomach or abdominal pain in last month	1.3	1.6	3.6	1.5	1.5	1.1	0.9	-1.2	1.9	1.4	1.5	0.5	1.3	1.1	1.1	1.2	0.7
Supplements: Glucosamine	1.2	1.5	3.0	1.2	1.0	1.0	1.2	-0.8	1.7	1.4	0.9	1.7	1.5	1.3	0.8	1.0	1.2
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	2.4	0.5	0.6	0.3	0.4	-0.4	1.6	0.0	0.9	0.9	0.6	0.1	1.0	0.7	-0.9
Medication: Atenolol	0.3	0.4	1.1	1.0	0.4	0.7	0.7	-0.0	0.6	-0.1	0.8	0.5	0.5	0.3	0.7	0.8	-0.5
Medication: Levothyroxine sodium	0.8	1.4	2.4	0.4	1.1	1.1	0.8	-1.5	1.5	1.4	1.3	0.6	1.2	1.4	1.4	1.2	1.1
Sitting height	2.7	18.9	24.6	-4.8	-4.4	-4.9	-4.9	3.6	-4.7	-4.3	-3.4	-5.0	-4.7	-3.9	-4.3	-4.6	-2.5
Chronic bronchitis/emphysema (father)	0.3	0.3	1.8	1.4	0.0	0.6	0.8	-0.2	0.1	0.6	0.4	0.4	0.7	0.3	-0.3	-0.4	0.2
High blood pressure (mother)	0.4	0.5	3.1	0.2	0.3	0.1	0.0	-1.3	-0.2	0.8	-0.6	0.6	0.4	0.4	1.8	0.8	-0.4
Body mass index (BMI)	2.7	11.3	26.2	-3.7	-3.5	-3.4	-2.7	2.2	-3.3	-3.2	-2.3	-5.1	-4.2	-3.3	-3.1	-3.5	-2.4
Impedance of leg (left)	2.5	12.0	31.9	4.6	3.4	3.1	3.9	-2.0	4.2	2.9	1.2	5.7	4.3	2.6	3.1	3.3	0.9
Leg predicted mass (left)	3.6	19.2	41.0	-5.7	-4.3	-4.4	-4.8	3.1	-4.9	-4.0	-2.1	-6.4	-5.1	-3.6	-4.2	-4.4	-1.9
Trunk fat mass	2.5	10.5	18.8	-3.7	-3.4	-3.3	-2.6	2.3	-3.5	-3.1	-2.7	-4.3	-3.8	-3.1	-3.3	-3.4	-2.1
Waist circumference	2.0	7.2	13.0	-2.7	-3.0	-2.7	-2.1	1.8	-2.5	-2.7	-2.0	-3.6	-3.3	-2.7	-2.3	-2.8	-2.5
Number of incorrect matches in round	1.0	1.6	3.5	-1.0	-1.4	-1.4	-1.1	0.9	-1.9	-1.1	-1.0	-1.2	-1.4	-1.3	-1.3	-1.6	-1.0
Past tobacco smoking	1.1	2.0	7.0	-0.5	-0.9	-0.6	0.1	2.7	-0.8	-1.8	-1.6	0.5	-0.4	-1.9	-1.8	-1.6	-1.8
Alcohol usually taken with meals	1.1	1.7	3.3	-0.1	-1.8	-1.5	-0.6	1.4	-1.5	-1.4	-0.5	-1.1	-1.4	-1.3	-1.5	-1.7	-1.2
Nervous feelings	0.6	1.1	2.8	1.3	0.9	0.4	0.5	-1.7	0.9	1.5	1.1	0.6	0.8	1.1	1.3	1.0	0.6
Frequency of tenseness / restlessness in last 2 weeks	3.3	5.1	7.8	-2.2	-2.5	-2.1	-2.0	2.5	-1.5	-2.7	-1.0	-1.8	-2.2	-2.4	-2.5	-2.8	-2.7
Hearing difficulty/problems with background noise	0.3	0.5	1.3	-0.8	-0.8	-0.2	-0.9	0.3	-0.5	-0.7	-0.2	0.0	-0.5	-1.1	-0.7	-0.7	-0.9
Hair/balding pattern: Pattern 2	0.2	0.3	1.2	-0.4	0.4	0.1	0.4	-0.2	1.1	0.0	0.3	0.4	0.3	0.4	0.7	1.0	0.7
Had menopause	0.3	0.3	1.4	-0.8	-0.3	-0.6	0.1	1.2	-0.6	-0.5	0.3	-0.1	-0.1	-0.5	-1.0	-0.6	-0.2
Had other major operations	0.2	0.2	1.2	-0.8	-0.5	-0.3	-1.1	0.4	0.2	-0.1	0.1	-0.7	-0.2	0.2	-0.3	-0.3	0.6
Forced vital capacity (FVC)	1.5	5.6	11.4	1.5	2.7	2.2	0.7	-1.7	1.8	2.4	3.4	2.0	2.7	3.0	2.4	2.6	2.9
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	3.3	-1.1	-0.7	-0.8	-1.3	0.9	-1.8	-1.5	-1.1	-0.5	-1.1	-0.8	-0.8	-0.5	-0.5
Ever unenthusiastic/disinterested for a whole week	2.2	2.7	4.3	-1.7	-1.6	-1.2	-1.5	2.1	-0.7	-2.1	-1.5	-0.8	-1.3	-1.9	-2.0	-2.0	-1.8
Qualifications: None of the above	0.7	1.6	4.0	1.4	0.6	0.7	1.0	-1.8	1.9	1.1	2.0	-0.2	0.8	1.2	1.7	1.2	0.2
Financial difficulties in last 2 years	1.5	2.0	5.0	-1.9	-1.7	-1.7	-1.3	0.8	-0.8	-1.1	-0.6	-2.2	-1.5	-1.4	-1.4	-1.7	-0.8
Mouth/teeth dental problems	0.9	1.3	4.7	-2.2	-0.9	-1.4	-1.4	-0.1	-1.7	-0.5	-0.6	-1.8	-1.3	-0.4	-0.4	-0.5	0.2
Heart attack	0.2	0.2	0.6	-0.4	-0.6	-0.2	-0.4	0.6	0.7	-0.7	-0.3	-0.1	-0.0	-0.2	-0.1	-0.2	-0.8
Allergy	2.4	5.5	8.4	1.7	2.7	2.4	2.0	-2.6	1.3	2.7	1.0	2.8	2.6	2.2	2.9	2.9	2.2
Pain all over the body in last month	0.3	0.3	2.1	0.1	0.6	0.6	0.6	-0.1	1.5	0.0	-0.4	0.3	0.0	-0.1	0.3	0.6	0.1
Diabetes (self-reported)	0.7	1.1	2.3	-0.6	-1.2	-0.8	0.4	1.0	-0.7	-1.1	-1.0	-1.5	-1.0	-1.3	-1.2	-1.4	-1.1
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	5.0	-0.1	-0.7	-0.2	-0.8	2.2	0.2	-1.3	-1.0	-0.1	-0.6	-0.7	-1.6	-1.4	-1.0
Medication: Ramipril	0.4	0.5	1.9	1.2	-0.2	0.0	0.5	-0.6	0.3	0.5	1.4	-0.7	0.3	0.8	0.1	0.1	0.9
Medication: Simvastatin	2.3	3.4	7.0	-0.6	-2.3	-1.5	-0.6	1.6	-1.4	-2.3	-2.2	-1.3	-1.8	-2.2	-1.7	-2.1	-2.6
Fluid intelligence score	0.4	0.8	3.8	0.0	-0.2	-0.2	0.2	2.0	-0.7	-0.8	-1.7	0.9	0.2	-0.6	-1.2	-0.6	0.2
Illnesses of siblings	1.6	2.3	3.9	-1.4	-1.8	-1.7	-1.4	1.3	-1.7	-1.4	-2.0	-1.3	-1.4	-1.4	-1.7	-1.7	-0.5
Neuroticism score	2.4	4.9	10.8	-1.7	-2.2	-2.0	-0.8	3.3	-1.7	-2.3	-2.1	-1.2	-1.7	-2.5	-3.1	-3.0	-2.0
Weight	3.2	15.6	32.6	-4.6	-4.1	-4.1	-3.8	2.9	-3.9	-3.8	-2.2	-5.7	-4.7	-3.6	-3.8	-4.1	-2.6
Impedance of arm (right)	1.0	4.7	13.3	2.7	2.3	2.2	2.3	-0.9	1.9	1.8	1.1	3.7	2.9	1.9	1.7	2.2	1.3
Arm fat percentage (right)	2.0	7.8	16.7	-3.1	-2.8	-2.7	-1.8	2.1	-3.0	-2.6	-2.2	-4.1	-3.4	-2.7	-3.0	-3.0	-1.8
Trunk fat-free mass	1.4	8.0	20.1	-3.9	-2.8	-2.9	-3.4	1.8	-2.9	-2.4	-0.6	-4.5	-3.3	-2.1	-2.7	-2.8	-0.9
Hip circumference	3.1	13.3	25.2	-3.7	-3.9	-3.8	-3.6	2.3	-3.9	-3.6	-2.4	-5.0	-4.5	-3.5	-3.3	-3.7	-2.7
Time employed in main current job	0.5	0.6	1.5	0.4	0.7	0.8	1.2	0.9	0.5	0.6	0.3	1.0	1.2	0.4	-0.8	-0.5	0.8
Alcohol intake versus 10 years previously	0.6	0.9	3.8	1.3	0.8	1.0	1.2	-0.1	1.9	0.4	1.3	0.7	1.1	0.2	0.2	0.4	0.1
Father’s age at death	0.3	0.4	1.1	0.3	-0.9	-0.5	0.1	0.4	0.7	-0.7	-0.6	-1.0	-0.6	-0.6	-0.6	-0.7	-0.4
Worrier / anxious feelings	0.2	0.3	1.6	0.8	0.3	0.1	0.7	0.3	-0.0	-0.2	0.1	1.3	0.5	-0.4	0.0	0.0	-0.9
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	3.8	-1.2	-1.0	-0.6	-0.6	2.0	-1.2	-1.3	-1.2	-0.6	-0.7	-1.2	-1.8	-1.8	-1.1
Falls in the last year	0.6	0.8	1.9	-1.2	-0.7	-0.8	-0.4	0.9	0.1	-0.8	-0.6	-1.4	-0.9	-0.8	-1.2	-1.2	-0.5
Hair/balding pattern: Pattern 3	0.5	0.8	3.1	1.4	0.6	0.4	0.4	-1.8	0.4	1.2	0.1	0.4	0.4	0.9	1.4	0.9	0.2
Number of live births	0.7	1.0	1.9	-0.7	1.4	0.7	0.9	-1.2	1.1	1.2	1.0	1.1	1.1	0.7	0.7	1.0	1.3
Forced expiratory volume in 1-second (FEV1)	1.2	4.2	6.7	1.1	2.4	1.7	0.7	-2.1	1.2	2.1	2.6	1.6	2.1	2.6	2.5	2.5	2.4
Pulse rate	0.2	0.4	2.8	-1.7	0.0	-0.1	-0.3	-0.3	-0.1	0.0	-1.3	0.2	-0.3	0.2	0.3	0.1	0.0
Happiness	0.2	0.3	1.0	-0.4	0.1	0.4	-0.7	0.8	1.0	-0.5	-0.4	0.8	0.2	-0.0	-0.0	0.0	-0.8
Noisy workplace	0.5	0.7	2.0	0.3	0.4	0.8	1.4	-0.8	1.4	1.0	1.1	-0.0	0.8	0.5	0.7	0.5	0.2
Qualifications: A levels/AS levels or equivalent	1.4	3.1	5.5	-1.2	-1.7	-2.0	-0.9	2.2	-2.3	-1.9	-1.7	-0.5	-1.3	-1.8	-2.0	-2.2	-1.8
Serious illness, injury or assault of a close relative in last 2 years	1.5	1.7	4.8	-0.8	-0.9	-0.6	0.5	2.2	-0.6	-1.9	-1.7	0.3	-0.5	-1.7	-1.8	-1.3	-1.4
Mouth/teeth dental problems: Dentures	0.3	0.5	1.5	0.2	0.1	0.6	1.2	1.1	0.8	0.3	-0.1	0.3	0.6	-0.1	-1.2	-0.8	0.7
Asthma	2.3	4.6	8.4	-2.5	-2.2	-2.4	-1.6	2.2	-1.2	-2.2	-1.2	-2.9	-2.4	-1.9	-2.5	-2.5	-1.4
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.9	0.9	0.4	0.7	-0.2	0.6	0.8	0.0	0.0	-0.3	-0.2	0.3	-0.4	-0.1	0.5
Medication: Cholesterol lowering	0.7	1.1	4.3	-0.2	-1.3	-0.8	-0.3	0.4	-0.8	-1.2	-1.9	-0.2	-0.7	-1.1	-0.4	-1.0	-2.1
Depression (self-reported)	2.4	2.9	4.8	-1.9	-2.1	-1.8	-2.2	1.3	-2.1	-1.5	-1.5	-0.8	-1.5	-1.5	-1.5	-2.0	-1.4
Medication: Lansoprazole	1.3	1.5	3.6	-0.8	-1.6	-1.4	-1.2	-1.4	-1.0	-0.9	-0.9	-1.9	-1.7	-1.0	0.3	-0.5	-1.5
Prospective memory result	4.8	5.9	9.3	2.0	2.5	2.5	1.6	-2.9	1.7	3.0	2.9	2.1	2.6	2.4	2.5	2.5	2.1
Lung cancer (father)	0.3	0.4	1.1	-1.0	0.2	0.2	0.9	0.8	0.7	0.3	0.2	0.2	0.8	0.2	-0.7	-0.3	0.7
Illnesses of mother	0.7	0.9	2.9	0.7	1.1	1.0	1.0	-0.8	1.2	0.9	1.2	-0.0	0.5	1.0	0.1	0.8	1.7
Forced expiratory volume in 1-second (FEV1), Best measure	2.0	6.4	9.7	1.6	2.8	2.1	1.0	-2.6	1.7	2.6	2.6	2.2	2.6	3.1	3.1	3.1	3.0
Pulse wave Arterial Stiffness index	0.1	0.1	0.4	-0.2	-0.2	0.1	-0.0	-0.3	-0.2	0.4	0.6	-0.1	0.1	0.4	-0.1	0.1	0.6
Impedance of arm (left)	0.7	3.2	10.4	2.1	1.9	1.8	1.8	-0.6	1.5	1.5	0.5	3.2	2.5	1.6	1.4	1.7	0.9
Arm fat mass (right)	2.6	10.9	22.8	-3.8	-3.4	-3.4	-2.6	2.4	-3.5	-3.1	-2.1	-4.8	-4.0	-3.1	-3.4	-3.5	-2.0
Trunk predicted mass	1.4	8.1	20.1	-3.9	-2.8	-2.9	-3.3	1.9	-3.0	-2.4	-0.7	-4.5	-3.3	-2.2	-2.7	-2.8	-1.0
Standing height	0.3	2.9	6.2	-2.5	-1.7	-2.0	-2.4	1.7	-1.8	-1.6	-0.3	-1.8	-1.4	-1.0	-1.9	-1.8	-0.5
Length of working week for main job	0.7	0.8	2.2	0.0	1.1	1.2	0.2	-0.0	1.3	0.9	0.7	0.8	1.2	1.0	0.1	0.4	1.5
Exposure to tobacco smoke at home	2.1	2.3	4.5	1.8	2.1	1.8	2.1	-0.5	0.6	1.7	1.3	1.1	1.7	1.7	1.1	1.3	1.5
Breastfed as a baby	1.0	1.3	3.3	1.8	0.7	1.3	0.8	-0.4	1.7	1.1	1.2	1.6	1.0	1.1	0.8	0.7	0.3
Tense / ‘highly strung’	0.5	0.9	1.4	-1.2	-0.8	-1.0	-0.3	1.1	-0.5	-1.1	-0.5	-0.9	-1.1	-0.9	-1.0	-0.9	-1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	2.9	4.5	7.7	-1.6	-2.4	-2.4	-1.7	2.0	-1.9	-2.1	-2.1	-1.7	-2.1	-2.2	-2.4	-2.8	-1.8
Hair/balding pattern: Pattern 4	1.2	2.9	5.0	1.3	2.0	2.2	1.8	-0.6	1.9	1.7	1.7	1.8	2.2	1.5	1.1	1.6	1.7
Birth weight of first child	1.0	1.8	3.3	-1.8	-1.3	-1.3	-1.3	1.7	-0.7	-1.1	-1.8	-0.9	-1.0	-0.9	-1.8	-1.6	-0.4
Peak expiratory flow (PEF)	0.2	0.5	2.3	-1.5	-0.4	-1.1	-0.7	0.3	-1.2	-0.4	-0.3	-0.7	-0.5	-0.4	-0.4	-0.4	0.3
Pulse wave reflection index	0.2	0.3	1.9	1.0	-0.0	0.0	0.1	-0.6	0.6	0.3	1.4	-0.4	0.2	0.2	0.4	0.4	0.1
Ever highly irritable/argumentative for 2 days	7.5	9.0	11.5	-3.4	-3.1	-3.1	-2.9	2.4	-2.9	-3.3	-2.1	-2.8	-3.3	-3.4	-2.6	-3.1	-3.3
Loud music exposure frequency	0.4	0.4	2.6	-0.5	-0.1	-0.0	-0.7	-0.5	0.5	-0.1	1.6	-0.4	-0.3	0.3	0.7	0.7	0.0
Qualifications: O levels/GCSEs or equivalent	1.2	1.9	5.9	-1.9	-0.9	-1.6	-0.7	1.2	-2.4	-1.2	-1.4	-0.9	-1.4	-1.1	-1.3	-1.1	-0.6
Mouth/teeth dental problems: Bleeding gums	2.2	2.9	7.0	2.6	1.4	1.7	1.6	-1.4	2.0	1.4	1.9	1.9	1.7	1.3	2.0	1.8	0.1
Blood clot in the leg (DVT)	0.2	0.3	1.5	-0.1	-0.3	0.2	-0.2	0.3	-0.4	-0.3	-1.2	0.7	-0.2	-0.3	-0.1	-0.4	-1.1
Medication: Paracetamol	0.2	0.3	1.5	1.2	0.5	0.6	0.1	-0.5	0.9	0.5	0.6	0.0	0.2	0.3	0.5	0.3	0.1
Headache pain in last month	0.2	0.3	0.7	0.1	-0.3	-0.2	-0.3	0.7	0.5	-0.7	-0.5	0.1	-0.3	-0.9	-0.6	-0.6	-0.9
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.9	0.5	0.2	-0.2	-0.0	0.4	0.2	0.0	0.9	-0.3	-0.2	0.1	-0.4	0.0	0.6
Glaucoma (self-reported)	2.9	3.4	7.6	-2.5	-1.9	-1.5	-1.2	1.8	-1.3	-1.8	-2.8	-1.3	-1.7	-1.8	-2.1	-2.2	-0.7
Gout (self-reported)	3.2	4.4	9.7	1.4	1.9	1.8	1.3	-2.8	1.4	2.1	2.3	2.3	2.1	2.2	3.1	2.6	1.0
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	2.5	0.5	1.0	0.8	0.5	-1.6	1.4	1.4	0.5	0.6	0.8	1.2	1.5	1.0	0.5
Medication: Amlodipine	0.3	0.5	2.0	0.3	0.7	0.3	0.3	-1.4	-0.4	0.8	0.3	-0.0	-0.0	0.7	1.3	0.9	-0.0
Medication: Ventolin 100micrograms inhaler	0.7	0.9	2.0	-1.4	-0.8	-1.0	-1.0	1.1	-0.1	-1.2	0.9	-1.1	-0.8	-0.6	-0.9	-0.9	-0.8
Birth weight	0.1	0.2	1.1	-0.3	0.2	0.2	-0.3	-0.5	-0.7	0.2	1.0	-0.3	-0.2	0.6	0.5	0.6	0.4
Chronic bronchitis/emphysema (mother)	1.3	1.5	2.6	-0.9	-1.2	-1.3	-1.2	1.4	-1.3	-1.6	-0.1	-0.7	-0.9	-1.6	-1.1	-1.3	-1.6
High blood pressure (siblings)	1.8	2.7	5.8	0.7	1.6	1.7	0.8	-1.9	1.3	1.6	2.2	1.6	1.5	1.6	2.4	2.2	0.5
Forced vital capacity (FVC), Best measure	1.8	6.7	10.7	1.8	2.9	2.3	0.7	-2.1	1.9	2.5	3.1	2.6	2.9	3.3	2.8	3.0	3.1
Body fat percentage	1.6	6.5	10.8	-2.5	-2.7	-2.5	-1.5	1.9	-2.5	-2.5	-2.4	-3.3	-3.0	-2.7	-2.7	-2.8	-2.1
Leg fat percentage (right)	0.6	2.2	4.7	-1.3	-1.7	-1.3	-0.5	0.9	-1.1	-1.2	-1.6	-2.2	-1.8	-1.7	-1.6	-1.8	-1.4
Arm fat-free mass (right)	2.6	13.4	25.9	-4.6	-3.7	-3.8	-3.8	2.7	-4.0	-3.4	-1.9	-5.1	-4.3	-3.2	-3.6	-3.7	-1.9
Exposure to tobacco smoke outside home	4.0	5.3	8.0	2.2	2.4	2.5	2.0	-1.7	2.8	2.5	2.4	1.9	2.6	2.5	2.3	2.4	1.7
Comparative body size at age 10	0.7	1.9	7.2	-1.1	-1.5	-1.5	-1.7	0.9	-1.9	-1.1	-0.4	-2.7	-1.5	-0.9	-1.1	-1.2	0.0
Number of full brothers	0.1	0.2	0.5	-0.1	-0.0	-0.2	-0.2	0.2	0.6	-0.6	-0.2	-0.5	-0.5	-0.3	-0.4	-0.3	-0.7
Worry too long after embarrassment	2.2	3.7	8.3	-1.7	-2.1	-2.1	-1.4	2.7	-1.6	-1.9	-1.6	-1.0	-1.4	-1.9	-2.9	-2.7	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	2.5	1.6	0.5	0.6	1.4	-0.2	0.9	0.5	0.9	1.0	0.9	0.8	0.5	0.4	0.2
Wheeze or whistling in the chest in last year	1.1	1.9	5.3	-1.0	-1.4	-1.2	-0.2	1.5	-0.0	-1.2	0.8	-2.3	-1.2	-1.4	-1.7	-1.8	-1.5
Number of children fathered	2.3	2.6	7.6	-2.8	-1.6	-1.6	-1.9	0.3	-1.4	-1.1	-2.3	-1.5	-1.9	-1.3	-1.2	-1.7	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	2.8	3.2	7.4	-2.5	-1.7	-1.8	-1.6	1.6	-1.8	-1.8	-1.4	-2.7	-1.9	-1.4	-1.7	-1.7	-0.7
Age at first live birth	1.2	2.1	3.2	-1.6	-1.4	-1.5	-1.2	1.7	-1.7	-1.4	-1.8	-0.9	-1.3	-1.4	-1.7	-1.6	-0.8
Pulse wave peak to peak time	0.1	0.1	0.5	0.1	0.1	-0.1	0.1	0.5	0.2	-0.5	-0.6	0.2	-0.0	-0.4	-0.1	-0.2	-0.7
Health satisfaction	0.8	1.0	3.1	-0.2	1.0	1.3	0.3	0.5	1.4	0.8	0.8	1.8	1.5	0.9	0.1	0.4	1.0
Shortness of breath walking on level ground	2.4	2.8	6.9	-2.6	-2.0	-1.7	-1.9	1.0	-1.0	-1.5	-1.1	-2.2	-1.9	-1.4	-1.3	-1.6	-1.4
Qualifications: College or University degree	1.4	4.3	11.5	-1.0	-1.8	-1.5	-0.7	3.4	-2.7	-2.5	-2.5	-0.0	-1.2	-2.4	-2.9	-2.2	-1.3
Eye problems/disorders: None of the above	0.2	0.2	0.7	-0.2	0.2	-0.2	-0.8	-0.0	-0.7	0.2	0.8	-0.4	-0.2	0.1	0.4	0.1	-0.4
Mouth/teeth dental problems: Loose teeth	3.1	3.6	4.7	2.0	2.0	2.2	2.1	-1.7	1.8	1.8	1.5	2.0	2.0	1.9	1.5	2.0	2.0
Emphysema/chronic bronchitis	0.4	0.5	1.2	-0.3	-0.6	-0.4	-0.4	1.1	0.9	-0.8	1.0	-0.4	0.1	-0.6	-0.6	-0.7	-0.9
Medication for pain relief, constipation, heartburn	0.1	0.2	1.1	-1.1	0.1	-0.2	-0.0	0.2	-0.9	0.1	-0.0	0.3	0.1	0.0	-0.2	-0.1	0.3
Neck or shoulder pain in last month	0.9	1.3	3.9	-1.0	-1.0	-1.0	-0.8	0.6	-1.1	-1.4	-1.1	-0.8	-1.4	-1.5	-0.5	-0.9	-2.0
Medication: Blood pressure	0.2	0.3	0.8	-0.0	0.3	0.7	0.2	-0.9	0.6	0.6	0.0	0.4	0.6	0.7	0.8	0.4	0.2
Angina (self-reported)	1.9	2.5	8.4	-0.5	-2.0	-1.3	-1.5	1.1	-0.7	-1.9	-0.5	-1.6	-1.6	-1.6	-1.2	-1.9	-2.9
Migraine (self-reported)	0.7	0.9	3.2	0.7	1.1	1.2	1.8	-0.2	0.5	1.0	-0.3	1.0	1.0	0.7	0.5	0.9	0.8
Medication: Ibuprofen	0.3	0.4	1.2	0.6	0.7	1.1	0.0	0.8	0.9	0.2	-0.0	0.6	0.5	0.6	-0.3	0.3	0.8
Medication: Allopurinol	6.8	9.0	19.1	1.9	2.8	3.0	1.4	-3.8	2.3	3.0	2.6	3.6	3.0	3.1	4.4	3.8	1.4
Medication: Omeprazole	0.4	0.5	1.6	1.1	0.6	0.9	0.9	0.2	1.3	0.2	0.7	0.9	0.9	-0.0	-0.1	0.2	-0.3
Medication: Seretide 50 evohaler	2.1	2.4	5.4	-1.1	-1.9	-2.0	-1.4	1.1	-0.7	-1.4	-1.1	-2.3	-1.8	-1.5	-1.3	-1.8	-1.4
Mean time to correctly identify matches	3.5	6.6	12.1	1.8	2.9	2.8	3.5	-1.4	1.3	2.7	2.0	3.4	3.1	2.8	1.9	2.6	2.4
Heart disease (mother)	0.6	0.8	2.2	-1.5	-1.1	-1.1	-0.6	0.5	-0.4	-0.8	-1.3	-0.4	-0.5	-0.8	-0.4	-0.8	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	3.5	-1.9	-1.3	-1.2	-1.4	-0.1	-0.9	-0.7	-1.5	-1.3	-1.1	-0.8	-0.0	-1.0	-1.2
Whole body fat mass	2.5	10.4	19.0	-3.7	-3.4	-3.2	-2.5	2.5	-3.4	-3.1	-2.5	-4.4	-3.7	-3.1	-3.4	-3.5	-2.2
Leg fat mass (right)	2.2	8.6	16.7	-3.2	-3.1	-2.8	-2.1	2.3	-2.8	-2.8	-2.2	-4.1	-3.4	-2.9	-3.2	-3.3	-2.1
Arm predicted mass (right)	2.5	12.8	22.6	-4.5	-3.6	-3.7	-3.6	2.8	-3.9	-3.4	-2.0	-4.8	-4.0	-3.2	-3.6	-3.7	-1.9
Pulse rate, automated reading	0.4	1.2	5.2	-1.6	-0.6	-0.9	-0.4	1.1	-0.9	-0.9	-2.3	-0.6	-1.0	-0.9	-1.1	-1.1	-0.7
Alcohol intake frequency.	2.2	5.1	11.2	-1.0	-2.2	-1.9	-1.2	2.4	-1.4	-2.3	-1.5	-3.3	-2.8	-2.5	-3.0	-2.8	-1.5
Comparative height size at age 10	0.3	1.5	4.5	-1.9	-1.4	-1.7	-1.7	0.5	-2.1	-0.8	-1.0	-0.4	-0.7	-0.9	-0.9	-1.2	-0.4
Number of full sisters	0.8	1.0	2.3	-0.3	-1.1	-1.0	-0.9	0.9	0.8	-1.0	-0.4	-1.5	-1.0	-1.2	-0.9	-1.3	-1.0
Suffer from ‘nerves’	0.3	0.5	1.0	-0.0	-0.7	-0.9	-0.1	0.6	-0.5	-0.4	-0.6	-1.0	-0.7	-0.8	-1.0	-1.0	-0.3
Overall health rating	1.4	3.1	6.7	1.9	1.6	2.3	1.3	-0.4	2.5	1.8	2.6	1.0	2.0	1.9	0.8	1.2	1.7
Chest pain or discomfort	1.7	2.4	4.3	-1.0	-1.9	-1.8	-1.4	1.6	-0.6	-1.5	-0.7	-1.3	-1.4	-1.6	-1.9	-2.1	-1.9
Had major operations	1.6	1.8	3.9	-1.1	-1.5	-1.3	-0.2	1.0	-1.3	-1.2	-1.2	-1.8	-1.4	-1.7	-2.0	-1.6	0.1
Age at last live birth	0.4	0.6	1.8	-1.4	-0.8	-0.7	-0.9	0.6	-0.6	-0.7	-1.0	-0.2	-0.4	-0.9	-0.6	-0.7	-0.7
Family relationship satisfaction	1.9	2.3	5.3	1.0	1.1	1.3	-0.9	-1.2	2.0	1.2	2.3	1.8	1.5	1.7	2.1	1.6	-0.1
Leg pain on walking	0.7	0.9	2.1	-0.2	0.8	1.0	1.4	-0.8	0.2	1.2	0.9	0.2	0.6	1.4	0.7	0.9	1.4
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	2.1	0.0	0.3	0.4	-0.1	0.2	1.4	-0.1	0.4	-0.5	0.1	0.1	-0.1	0.3	0.4
Commuting to job workplace: Car/motor vehicle	0.8	0.9	2.4	-0.7	-0.9	-0.8	0.1	1.2	0.3	-0.8	-1.5	-0.6	-0.2	-1.2	-1.1	-1.3	-1.0
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	2.2	-0.2	-0.4	-0.8	-0.4	-0.7	-1.5	-0.2	-1.0	-0.2	-0.6	-0.1	0.4	-0.1	-0.4
Medication: Aspirin	0.4	0.5	2.1	0.4	-1.1	-0.5	-0.9	-1.1	0.1	-0.2	-0.9	-0.1	-0.3	-0.2	0.7	-0.2	-1.4
Supplements: Vitamin C	1.2	1.4	3.1	1.2	1.2	0.9	1.0	-0.3	1.8	1.3	1.0	1.3	1.4	1.5	0.6	0.9	1.5
Knee pain experienced in last month	0.4	0.6	2.6	0.3	0.1	0.2	0.2	-1.1	1.6	-0.1	0.1	-1.1	-0.3	-0.0	1.3	0.7	-0.9
Hypertension (Self-reported)	2.9	8.1	12.5	2.1	3.1	3.5	2.5	-2.3	2.2	3.3	2.6	2.6	3.1	3.5	2.6	2.8	3.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.4	0.9	-0.8	-0.2	0.3	-0.1	0.8	-0.6	-1.2	-0.4	-0.5	-1.0	-0.3	-0.3	-0.9
Illnesses of father: Heart disease	2.4	3.3	6.7	-2.1	-1.6	-1.7	-1.8	1.8	-0.9	-2.2	-2.6	-0.6	-1.8	-1.9	-1.8	-1.8	-1.9
Illnesses of siblings: Diabetes	0.7	0.8	1.8	-1.0	-0.8	-0.8	-0.6	0.9	0.1	-1.1	-1.3	-0.8	-1.0	-1.0	-1.0	-1.0	-0.6
Smoking status: Previous	0.9	1.3	5.7	0.4	0.8	0.5	-0.2	-2.4	0.3	1.6	0.8	-0.5	0.1	1.5	1.7	1.3	1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	3.2	-0.7	-0.8	-0.8	-1.7	1.8	-0.7	-1.7	0.3	-1.0	-0.8	-0.7	-1.1	-0.9	-1.0
Whole body fat-free mass	2.2	12.8	29.5	-4.8	-3.5	-3.6	-4.0	2.4	-3.9	-3.2	-1.3	-5.4	-4.2	-2.8	-3.5	-3.5	-1.3
Leg fat-free mass (right)	3.7	19.8	42.8	-5.8	-4.4	-4.5	-5.0	3.0	-5.0	-4.1	-1.9	-6.5	-5.3	-3.6	-4.3	-4.4	-1.9
Arm fat percentage (left)	2.3	9.2	18.3	-3.4	-3.1	-3.0	-2.2	2.1	-3.3	-2.9	-2.4	-4.3	-3.7	-3.0	-3.1	-3.2	-2.0
Average weekly red wine intake	0.4	0.6	3.5	-0.4	-0.6	-0.7	-0.0	0.5	-1.9	-0.7	-1.1	0.8	-0.3	-0.3	-0.7	-0.6	0.2
Handedness (chirality/laterality): Left-handed	0.1	0.2	0.5	-0.3	-0.4	-0.0	-0.7	-0.5	-0.4	-0.0	-0.0	0.6	-0.2	0.1	0.5	0.0	-0.6
Mood swings	6.7	12.0	19.5	-3.6	-3.2	-3.1	-2.5	4.4	-2.8	-3.9	-3.0	-3.0	-3.3	-3.9	-4.3	-4.1	-2.9
Loneliness, isolation	0.4	0.5	2.9	-0.3	-0.3	-0.5	-0.7	0.3	1.2	-0.7	0.3	-0.5	-0.3	-0.5	0.2	-0.5	-1.7
Long-standing illness, disability or infirmity	0.8	1.2	3.1	1.4	0.9	1.5	1.5	-0.1	1.8	0.9	1.1	1.2	1.4	0.9	0.6	0.6	0.3
Ever had bowel cancer screening	0.2	0.2	2.1	1.5	-0.3	-0.4	0.2	-0.5	-0.6	0.3	-0.2	0.1	-0.0	0.0	0.2	-0.1	-0.3
Diabetes diagnosed by doctor	1.0	1.6	2.6	-1.1	-1.5	-1.1	-0.1	0.7	-0.9	-1.2	-1.6	-1.4	-1.2	-1.6	-1.0	-1.5	-1.5
Ever had stillbirth, spontaneous miscarriage or termination	6.7	7.2	12.2	1.7	3.0	3.0	2.7	-2.0	1.6	3.3	1.6	3.5	3.2	3.0	2.2	2.6	3.0
Friendships satisfaction	1.6	2.0	4.3	1.1	1.1	1.7	-0.3	-1.1	2.1	1.4	1.7	1.9	1.5	1.6	1.6	1.1	0.1
Qualifications: nursing, teaching	3.5	5.4	8.5	-2.1	-2.3	-2.4	-2.9	2.1	-2.9	-2.3	-2.4	-1.7	-2.4	-2.2	-2.5	-2.5	-1.4
Commuting to job workplace: Walk	0.5	0.6	1.5	-0.6	-0.9	-1.0	-1.2	-1.0	-1.2	-0.1	-0.5	-0.5	-1.0	-0.1	0.5	-0.2	-0.2
Eye problems/disorders: Cataract	0.3	0.3	1.0	-0.5	-0.5	-0.1	-0.0	0.9	0.2	-0.4	-0.9	0.3	0.1	-0.6	-1.0	-0.8	-0.2
Mouth/teeth dental problems: Mouth ulcers	1.2	1.8	4.4	-0.7	-1.0	-1.4	-0.4	1.8	-0.6	-2.0	-1.3	-0.9	-1.3	-1.8	-1.2	-1.2	-2.1
Medication for cholesterol	0.4	0.6	3.3	-0.7	-0.4	-0.9	0.2	-0.1	-0.9	-0.5	-1.8	0.1	-0.5	-0.9	-0.2	-0.5	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.1	2.7	-1.0	-1.6	-1.4	-1.4	0.6	-0.0	-0.8	-0.9	-1.3	-1.0	-1.0	-0.8	-1.2	-0.6
Back pain experienced in last month	0.3	0.4	1.6	1.1	-0.1	0.3	-0.0	-0.8	1.3	-0.2	0.1	0.4	0.1	-0.5	0.6	0.2	-1.2
Mineral and other dietary supplements	0.8	1.1	3.5	-1.1	-0.7	-0.8	-1.1	-0.2	-1.9	-0.8	-0.9	-1.7	-1.5	-0.8	-0.2	-0.4	-0.6
Breast cancer (self-reported)	3.1	3.7	6.2	-1.9	-1.9	-2.2	-2.4	1.4	-2.3	-2.3	-1.0	-1.8	-2.2	-1.7	-1.1	-1.6	-2.5
Asthma (self-reported)	2.0	3.9	6.8	-2.3	-2.1	-2.4	-1.3	2.0	-1.1	-2.0	-1.1	-2.6	-2.2	-1.7	-2.2	-2.3	-1.4
Osteoporosis (self-reported)	0.2	0.3	1.1	-1.1	-0.2	-0.1	-0.8	0.8	-0.3	-0.3	0.2	-0.3	-0.0	-0.6	-0.6	-0.5	-0.3
Osteoarthritis (self-reported)	0.5	0.7	1.4	0.5	0.9	1.0	0.4	-1.0	0.1	1.1	0.4	0.3	0.5	0.8	0.9	1.1	1.2
Medication: Aspirin	0.5	0.7	2.7	0.2	-1.2	-0.7	-1.1	-1.3	-0.2	-0.1	-0.8	-0.3	-0.4	-0.1	1.0	-0.2	-1.6
Medication: Gliclazide	2.5	2.9	7.6	-1.1	-2.0	-1.6	-0.5	1.0	-1.2	-2.0	-2.0	-1.6	-1.7	-2.1	-0.9	-1.8	-2.8
Illnesses of father: None of the above (group 1)	0.3	0.4	2.5	0.2	0.0	-0.2	-0.1	-0.1	0.5	0.2	1.6	-1.4	-0.2	0.0	-0.1	-0.0	0.5
Smoking status: Current	1.3	2.1	5.6	0.6	1.4	1.6	0.4	-0.8	2.0	1.7	1.7	0.8	1.8	1.6	0.8	1.1	2.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	6.7	14.2	21.7	2.3	4.2	3.8	2.5	-3.9	2.4	4.4	3.1	3.7	3.9	4.7	4.4	4.2	4.2
Whole body water mass	2.3	12.9	29.2	-4.8	-3.5	-3.7	-4.0	2.4	-4.0	-3.2	-1.4	-5.4	-4.2	-2.8	-3.4	-3.5	-1.3
Leg predicted mass (right)	3.8	20.5	43.2	-5.9	-4.4	-4.6	-5.1	3.1	-5.1	-4.2	-2.0	-6.6	-5.3	-3.7	-4.3	-4.5	-1.9
Arm fat mass (left)	2.9	11.9	23.9	-4.1	-3.6	-3.6	-2.9	2.3	-3.7	-3.2	-2.4	-4.9	-4.2	-3.3	-3.3	-3.5	-2.3
Number of self-reported non-cancer illnesses	0.3	0.5	1.6	0.6	0.4	1.0	0.8	0.2	1.3	0.8	0.2	1.0	1.0	0.8	-0.1	-0.1	0.7
Average weekly champagne plus white wine intake	0.1	0.2	1.0	0.3	0.3	-0.3	0.9	-0.1	0.2	0.4	0.1	-0.3	0.1	0.5	0.0	0.3	1.0
Miserableness	11.4	19.7	33.5	-4.4	-4.4	-3.8	-3.1	5.6	-3.6	-5.0	-4.2	-3.4	-3.9	-4.9	-5.8	-5.5	-3.6
Guilty feelings	2.9	4.4	7.1	-1.4	-2.4	-2.3	-0.9	2.3	-2.3	-2.4	-1.6	-1.3	-2.0	-2.7	-2.4	-2.4	-2.1
Wears glasses or contact lenses	3.2	3.7	8.2	-1.0	-2.0	-2.1	-0.9	2.9	-1.0	-2.2	-1.3	-1.6	-1.7	-1.9	-2.8	-2.6	-1.2
Ever taken oral contraceptive pill	0.6	0.7	1.9	0.4	0.8	0.5	1.2	-0.7	0.5	1.0	0.7	0.2	0.8	0.8	0.5	0.9	1.4
Hearing aid user	0.8	0.9	2.8	0.1	-1.2	-0.7	-1.7	0.4	-0.4	-0.9	-0.5	-1.4	-1.2	-0.5	-0.8	-1.2	-0.6
Mother’s age at death	1.2	1.5	3.8	-0.3	-1.6	-1.6	-1.8	-0.6	-1.2	-0.9	-1.2	-1.2	-1.2	-1.0	0.1	-1.0	-1.9
Financial situation satisfaction	0.3	0.3	1.9	-1.1	-0.1	-0.2	-1.4	-0.4	0.7	-0.0	0.5	-0.5	-0.3	-0.1	0.4	0.2	-0.1
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.7	0.9	0.1	0.6	0.4	0.2	0.5	0.3	0.7	-0.3	0.2	0.2	-0.0	0.2	0.7
Commuting to job workplace: Public transport	1.6	1.9	4.8	0.7	1.8	1.9	1.3	-0.1	-0.2	1.1	1.4	1.6	1.3	1.4	0.4	1.6	2.2
Eye problems/disorders: Glaucoma	0.8	0.9	5.0	-1.8	-0.7	-0.3	-0.7	0.3	-0.8	-0.4	-2.2	0.2	-0.5	-0.4	-0.9	-0.8	0.8
Medication: Blood pressure	3.0	5.7	13.7	2.8	2.4	2.7	2.0	-1.0	2.5	2.3	3.7	2.4	2.8	2.4	1.7	2.0	1.8
Pain type(s) experienced in last month: Hip pain	1.9	2.4	4.8	1.6	2.1	2.2	2.1	-0.1	1.9	1.1	1.0	1.6	1.8	1.3	1.2	1.6	1.0
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.9	0.6	-0.0	0.1	0.4	0.0	0.8	0.0	0.2	1.0	0.6	0.1	0.5	0.2	-0.6
High cholesterol (Self-reported)	0.4	0.7	1.9	0.7	-1.0	-0.7	-0.1	0.2	-0.7	-0.9	-1.4	-0.2	-0.7	-1.0	-0.3	-0.7	-1.4
Medication: Bendroflumethiazide	0.6	1.0	2.2	1.0	1.1	1.2	1.0	-0.2	1.5	0.7	0.8	1.1	1.1	0.8	0.9	1.1	0.4
Medication: Paracetamol	0.3	0.4	1.0	1.0	0.7	0.9	0.5	-0.5	0.3	0.6	0.6	0.5	0.6	0.6	0.5	0.7	0.7
Medication: Lisinopril	0.4	0.5	2.3	0.8	0.2	0.4	1.5	-0.6	0.6	0.6	1.4	0.1	0.6	0.5	0.5	0.5	0.2
Medication: Atorvastatin	0.1	0.1	0.6	-0.5	0.2	0.5	-0.2	0.3	0.7	0.0	0.5	0.1	0.4	0.4	0.2	0.3	0.3
Illnesses of father: High blood pressure	0.4	0.5	1.5	-1.1	-0.3	-0.2	-0.7	0.8	-0.5	-0.9	-1.2	0.2	-0.3	-0.6	-0.3	-0.3	-0.9
Alcohol drinker status: Never	4.3	5.2	10.2	-1.4	-2.2	-1.6	-1.1	3.1	-2.4	-2.5	-2.4	-2.2	-2.2	-2.4	-3.2	-2.7	-1.3
Ever smoked	2.4	4.2	8.4	1.5	1.6	1.7	0.3	-2.6	2.2	2.2	2.9	0.5	1.6	2.6	2.4	2.4	2.1
Basal metabolic rate	2.6	14.6	32.8	-5.0	-3.8	-4.0	-4.2	2.6	-4.1	-3.4	-1.6	-5.7	-4.5	-3.1	-3.6	-3.8	-1.7
Leg fat percentage (left)	0.8	2.7	6.0	-1.6	-1.9	-1.6	-0.8	0.8	-1.5	-1.3	-1.5	-2.5	-2.0	-1.8	-1.7	-1.9	-1.4
Arm fat-free mass (left)	2.4	12.1	26.0	-4.5	-3.5	-3.8	-3.7	2.2	-3.6	-3.2	-1.6	-5.1	-4.2	-3.0	-3.2	-3.4	-1.8
Number of operations (self-reported)	4.0	6.0	10.1	-2.5	-2.7	-2.3	-1.6	2.1	-1.3	-2.5	-2.4	-3.2	-2.8	-2.9	-3.0	-2.8	-1.1
Average weekly beer plus cider intake	4.7	6.8	9.7	1.1	3.0	3.1	0.7	-2.6	3.0	2.9	2.2	2.5	2.9	3.1	3.0	2.9	2.2
Irritability	1.1	1.9	7.8	-1.4	-0.6	-0.6	-0.6	2.8	-0.7	-1.3	-1.2	-0.9	-1.1	-1.2	-2.3	-1.7	-0.1
Risk taking	4.7	6.9	11.5	-2.2	-2.8	-3.0	-0.8	2.4	-2.2	-3.3	-2.8	-1.6	-2.7	-3.4	-2.5	-2.8	-3.2
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.6	-0.6	-1.1	-0.8	-1.0	1.0	-0.3	-1.1	-0.5	-1.3	-1.0	-0.6	-0.9	-0.9	-0.4
Fractured/broken bones in last 5 years	4.5	5.8	13.0	-1.1	-2.4	-1.9	-2.0	3.6	-1.5	-2.6	-1.6	-2.4	-2.3	-2.6	-3.4	-3.1	-1.8
Age started oral contraceptive pill	1.9	2.4	4.1	-1.2	-1.7	-1.1	-0.8	1.9	-2.0	-1.9	-1.5	-0.4	-1.1	-1.6	-1.9	-1.9	-1.5
Diastolic blood pressure, automated reading	1.4	4.2	12.0	0.5	2.6	2.3	1.1	-1.6	1.3	2.4	1.7	1.3	1.8	2.7	1.7	2.4	3.5
Ever depressed for a whole week	1.1	1.3	2.4	-1.5	-1.2	-1.0	-0.7	0.6	-1.3	-1.1	-1.1	-0.4	-1.1	-1.4	-1.4	-1.6	-1.0
Unable to work because of sickness or disability	0.3	0.4	1.0	-0.5	-0.8	-0.6	-1.0	-0.6	-0.5	-0.3	-0.4	-0.8	-0.6	-0.3	0.2	-0.2	-0.9
Commuting to job workplace: Cycle	8.2	9.9	16.9	-3.2	-3.7	-3.6	-4.1	1.3	-2.8	-3.1	-2.6	-4.0	-3.8	-2.9	-2.2	-3.0	-2.5
Myopia	1.5	2.2	5.0	-1.3	-1.4	-1.6	-0.8	2.2	-1.6	-1.4	-0.3	-1.4	-1.3	-1.5	-2.1	-1.9	-0.5
Vascular/heart problems diagnosed by doctor	1.7	4.7	8.0	-1.7	-2.3	-2.7	-1.9	1.6	-1.4	-2.6	-2.1	-1.9	-2.4	-2.8	-1.7	-2.0	-2.6
Cholesterol lowering medication	1.0	1.5	2.3	-0.3	-1.4	-1.2	-1.0	0.7	-1.5	-1.1	-1.2	-1.2	-1.5	-1.4	-1.1	-1.4	-1.2
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	2.4	1.2	0.8	1.2	0.6	-0.6	1.6	0.5	0.4	1.1	1.0	0.3	0.6	0.7	-0.3
Pain experienced in last month	0.3	0.6	4.2	-0.9	-0.3	-0.5	-0.7	0.2	-2.0	0.2	0.6	-0.2	-0.3	0.5	-0.5	-0.3	1.0
Supplements: Calcium	0.6	0.6	2.5	0.1	-0.6	-0.4	0.2	1.6	0.4	-0.8	-0.5	-0.8	-0.4	-0.8	-1.5	-1.0	-0.2
Basal cell carcinoma (self-reported)	0.9	1.0	2.4	1.0	1.1	1.1	1.6	-0.9	0.1	1.1	0.7	1.0	1.0	1.0	0.7	1.2	1.0
Heart attack/myocardial infarction (self-reported)	0.5	0.7	1.6	-0.9	-1.1	-0.7	-1.1	0.8	0.1	-1.2	-0.8	-0.6	-0.6	-0.7	-0.4	-0.6	-1.2
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	2.1	0.0	-0.4	0.1	-0.3	0.5	-0.3	-0.6	-1.5	0.4	-0.4	-0.6	-0.2	-0.6	-1.4
Heart disease (siblings)	1.2	1.4	4.0	-0.5	-0.7	-0.9	-0.1	1.9	-0.2	-1.5	-0.4	-1.5	-1.0	-1.4	-2.0	-1.5	-1.0
Alcohol drinker status: Previous	0.4	0.5	3.4	0.8	-0.4	-0.4	-0.6	-0.2	-0.7	0.2	0.6	-1.9	-0.8	0.1	-0.3	-0.5	0.5
Pack years of smoking	0.4	0.6	2.4	-0.1	-1.1	-0.9	-0.2	0.3	-0.0	-0.7	-0.1	-1.6	-0.7	-0.8	-0.9	-1.0	-0.6
Impedance of whole body	1.2	5.9	19.4	3.2	2.5	2.2	2.9	-0.9	2.6	1.9	0.3	4.4	3.2	1.8	1.9	2.3	0.8
Leg fat mass (left)	2.4	9.5	18.7	-3.4	-3.3	-3.0	-2.3	2.3	-3.1	-2.9	-2.2	-4.3	-3.6	-3.0	-3.3	-3.4	-2.2
Arm predicted mass (left)	2.3	11.5	24.7	-4.4	-3.4	-3.6	-3.6	2.3	-3.5	-3.2	-1.4	-5.0	-4.1	-2.9	-3.2	-3.4	-1.8