Best TWAS P=6.65e-11 · Best GWAS P=4.51e-15 conditioned to 0.00376
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | DYM | 0.30 | 0.01 | enet | 15 | 0.01 | 1.2e-01 | 7.2 | 6.5 | 6.7e-11 | 0.81 | 0.03 | 0.82 | TRUE |
| 2 | GTEx | Esophagus Mucosa | DYM | 0.12 | 0.01 | enet | 12 | 0.04 | 1.0e-03 | 7.6 | 5.6 | 2.0e-08 | 0.73 | 0.02 | 0.96 | FALSE |
| 3 | YFS | Blood | DYM | 0.05 | 0.05 | lasso | 4 | 0.04 | 1.5e-13 | -4.6 | 6.0 | 2.2e-09 | 0.76 | 1.00 | 0.00 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | C18orf32 | 0.04 | 0.03 | blup | 48 | 0.04 | 6.5e-05 | 4.3 | 6.3 | 2.9e-10 | 0.57 | 0.00 | 0.99 | TRUE |