Best TWAS P=7.62e-08 · Best GWAS P=6.28e-09 conditioned to 0.00939
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Frontal Cortex BA9 | GTPBP3 | 0.44 | 0.05 | lasso | 9 | 0.09 | 2.3e-03 | 3.7 | 5.4 | 7.6e-08 | -0.04 | 0.05 | 0.09 | TRUE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | HAUS8 | 0.13 | 0.10 | blup | 55 | 0.11 | 7.8e-12 | -4.5 | 5.2 | 2.6e-07 | 0.73 | 0.37 | 0.62 | TRUE |
3 | The Cancer Genome Atlas | Stomach Adenocarcinoma | HAUS8 | 0.06 | 0.04 | blup | 55 | 0.04 | 1.0e-03 | -4.6 | 5.1 | 3.1e-07 | 0.60 | 0.03 | 0.50 | FALSE |
4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | OCEL1 | 0.18 | 0.08 | blup | 53 | 0.11 | 1.4e-08 | -4.2 | -5.1 | 3.1e-07 | -0.10 | 0.00 | 0.85 | TRUE |