[Hub]/) : Traits : Basal metabolic rate :

chr6:80,120,201-81,872,212

Best TWAS P=1.32e-18 · Best GWAS P=1.62e-14 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum RP11-250B2.6 0.16 0.05 lasso 6 0.06 7.8e-04 6.2 -6.8 1.4e-11 -0.57 0.19 0.52 FALSE
2 GTEx Brain Cerebellum RP11-250B2.5 0.43 0.11 lasso 5 0.14 4.7e-05 -6.9 -6.8 8.6e-12 -0.76 0.09 0.80 FALSE
3 GTEx Cells EBV-transformed lymphocytes RP11-250B2.6 0.21 0.03 enet 37 0.13 4.7e-05 5.0 -6.0 2.0e-09 -0.23 0.14 0.08 TRUE
4 GTEx Cells Transformed fibroblasts BCKDHB 0.16 0.02 enet 42 0.04 3.7e-04 4.5 7.8 6.2e-15 0.49 0.26 0.63 TRUE
5 GTEx Esophagus Mucosa RP11-250B2.6 0.20 0.16 lasso 7 0.23 3.3e-15 -6.7 -6.7 1.9e-11 -0.65 0.80 0.20 FALSE
6 GTEx Heart Atrial Appendage RP11-250B2.6 0.20 0.00 enet 17 0.03 2.6e-02 -4.1 -8.8 1.3e-18 -0.41 0.05 0.52 TRUE
7 GTEx Heart Left Ventricle RP11-250B2.6 0.09 0.00 enet 6 0.02 2.0e-02 6.9 -6.5 6.7e-11 -0.82 0.04 0.79 TRUE
8 GTEx Lung RP11-250B2.6 0.09 0.05 enet 16 0.07 5.3e-06 4.6 -6.6 3.1e-11 -0.36 0.82 0.04 TRUE
9 GTEx Muscle Skeletal RP11-250B2.6 0.07 0.04 lasso 5 0.04 4.2e-05 7.5 -7.7 1.2e-14 -0.94 0.01 0.99 TRUE
10 GTEx Testis RP11-250B2.5 0.13 0.17 lasso 3 0.14 7.0e-07 -6.8 -6.6 3.9e-11 -0.88 0.04 0.95 TRUE
11 GTEx Thyroid BCKDHB 0.17 0.06 lasso 8 0.10 3.4e-08 4.6 6.1 8.5e-10 0.46 0.97 0.03 TRUE
12 METSIM Adipose RP11-250B2.6 0.04 0.04 lasso 12 0.02 1.7e-04 6.5 -5.8 5.6e-09 -0.60 0.66 0.12 FALSE
13 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma BCKDHB 0.12 0.06 lasso 4 0.06 4.2e-07 5.9 -5.5 2.9e-08 -0.75 0.40 0.58 FALSE