Best TWAS P=3.68e-08 · Best GWAS P=7.83e-08 conditioned to 0.0533
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SBDS | 0.08 | 0.05 | lasso | 3 | 0.04 | 5.4e-06 | 5.4 | 5.3 | 9.5e-08 | 1.00 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Brain Putamen basal ganglia | GS1-124K5.4 | 0.31 | 0.32 | enet | 23 | 0.36 | 1.7e-09 | 4.4 | 5.5 | 3.7e-08 | 0.74 | 0.17 | 0.77 | TRUE |
| 3 | GTEx | Muscle Skeletal | VKORC1L1 | 0.05 | 0.02 | lasso | 3 | 0.02 | 2.9e-03 | 4.5 | 5.2 | 1.5e-07 | 0.80 | 0.03 | 0.89 | FALSE |