[Hub]/) : Traits : Basal metabolic rate : ← →

chr7:70,996,097-73,789,730

Best TWAS P=4.31e-13 · Best GWAS P=1.43e-12 conditioned to 0.426

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
13	METSIM	Adipose	MLXIPL	0.12	0.14	lasso	4	0.13	1.8e-19	7.007	7.2	4.3e-13	0.80	0.02	0.98	TRUE
1	CommonMind	Brain Pre-frontal Cortex	DNAJC30	0.13	0.07	enet	32	0.07	2.7e-09	5.408	6.0	1.5e-09	0.36	0.99	0.00	TRUE
17	The Cancer Genome Atlas	Skin Cutaneous Melanoma	CALN1	0.37	0.04	enet	10	0.25	3.1e-07	-6.357	5.4	6.8e-08	0.05	0.01	0.96	TRUE
12	GTEx	Thyroid	MLXIPL	0.23	0.14	lasso	7	0.15	2.1e-11	6.326	7.2	4.5e-13	0.73	0.02	0.98	FALSE
5	GTEx	Cells Transformed fibroblasts	MLXIPL	0.13	0.06	enet	6	0.09	2.2e-07	6.901	7.2	6.4e-13	0.77	0.02	0.98	FALSE
15	The Cancer Genome Atlas	Lung Adenocarcinoma	MLXIPL	0.04	0.03	lasso	1	0.02	2.3e-03	6.987	7.0	2.8e-12	0.83	0.00	0.97	FALSE
9	GTEx	Skin Sun Exposed Lower leg	MLXIPL	0.12	0.09	lasso	4	0.06	6.1e-06	6.876	7.0	3.1e-12	0.69	0.04	0.96	FALSE
2	GTEx	Adipose Subcutaneous	MLXIPL	0.11	0.07	enet	16	0.07	1.6e-06	6.326	6.9	5.3e-12	0.70	0.04	0.96	FALSE
10	GTEx	Spleen	NCF1B	0.22	0.10	enet	9	0.08	5.1e-03	6.661	-6.9	6.2e-12	-0.88	0.02	0.63	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	MLXIPL	0.11	0.11	lasso	3	0.06	2.7e-04	6.901	6.8	1.0e-11	0.62	0.02	0.96	FALSE
3	GTEx	Adipose Visceral Omentum	MLXIPL	0.16	0.02	lasso	3	0.03	7.8e-03	6.238	6.8	1.2e-11	0.67	0.15	0.83	FALSE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	MLXIPL	0.06	0.05	lasso	2	0.05	5.1e-10	6.987	6.7	2.1e-11	0.77	0.00	1.00	FALSE
11	GTEx	Testis	MLXIPL	0.10	0.00	lasso	3	0.00	3.3e-01	4.691	6.3	2.2e-10	0.58	0.03	0.43	FALSE
16	The Cancer Genome Atlas	Prostate Adenocarcinoma	MLXIPL	0.08	0.05	enet	4	0.05	5.3e-06	6.987	6.0	1.7e-09	0.70	0.00	1.00	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	BCL7B	0.05	0.01	blup	5	0.03	1.3e-03	6.987	-5.9	3.1e-09	-0.93	0.00	0.63	FALSE
4	GTEx	Adipose Visceral Omentum	NSUN5	0.07	0.03	enet	11	0.04	4.0e-03	6.992	5.7	1.3e-08	0.48	0.02	0.73	FALSE
7	GTEx	Lung	MLXIPL	0.10	0.07	enet	14	0.07	6.3e-06	6.326	5.2	1.7e-07	0.50	0.08	0.80	FALSE
6	GTEx	Heart Left Ventricle	MLXIPL	0.14	0.00	enet	24	0.01	1.3e-01	-0.003	5.2	2.0e-07	0.38	0.09	0.54	FALSE