[Hub]/) : Traits : Basal metabolic rate :

chr9:102,162,230-103,803,109

Best TWAS P=1.33e-12 · Best GWAS P=9.75e-13 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TEX10 0.18 0.10 lasso 7 0.12 2.2e-14 -4.2 5.5 4.4e-08 0.65 0.82 0.18 FALSE
2 GTEx Artery Aorta INVS 0.15 0.10 enet 19 0.12 4.9e-07 6.0 5.5 2.8e-08 0.72 0.34 0.58 FALSE
3 GTEx Brain Cerebellar Hemisphere INVS 0.37 0.01 lasso 8 0.01 1.6e-01 5.7 5.2 2.1e-07 0.48 0.05 0.19 FALSE
4 GTEx Cells Transformed fibroblasts INVS 0.16 0.10 enet 17 0.17 8.0e-13 6.0 5.5 3.9e-08 0.61 0.88 0.12 FALSE
5 GTEx Heart Left Ventricle INVS 0.11 0.05 enet 15 0.04 2.6e-03 2.1 5.6 2.8e-08 0.72 0.04 0.84 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic TEX10 0.10 0.09 lasso 4 0.10 3.1e-06 4.5 5.9 2.9e-09 0.92 0.02 0.98 FALSE
7 GTEx Skin Sun Exposed Lower leg INVS 0.19 0.06 enet 30 0.11 1.5e-09 6.0 5.9 3.9e-09 0.79 0.02 0.98 FALSE
8 GTEx Skin Sun Exposed Lower leg TEX10 0.27 0.27 lasso 8 0.28 7.0e-23 7.1 7.1 1.3e-12 1.00 0.01 0.99 TRUE
9 YFS Blood INVS 0.15 0.14 lasso 7 0.24 1.4e-77 2.4 5.5 4.4e-08 0.78 0.02 0.98 FALSE
10 The Cancer Genome Atlas Bladder Urothelial Carcinoma INVS 0.27 0.05 lasso 8 0.13 3.4e-11 5.7 5.5 4.4e-08 0.68 0.20 0.80 FALSE
11 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma INVS 0.10 0.03 blup 107 0.07 4.0e-04 6.9 6.0 2.3e-09 0.89 0.01 0.96 FALSE
12 The Cancer Genome Atlas Lung Adenocarcinoma INVS 0.08 0.06 blup 106 0.07 7.0e-09 -3.7 5.2 2.6e-07 0.70 0.95 0.05 FALSE
13 The Cancer Genome Atlas Lung Squamous Cell Carcinoma INVS 0.09 0.02 enet 11 0.04 4.0e-05 5.7 5.8 8.5e-09 0.66 0.02 0.77 FALSE
14 The Cancer Genome Atlas Pancreatic Adenocarcinoma INVS 0.16 0.12 enet 8 0.08 2.8e-04 6.1 6.2 6.2e-10 0.77 0.26 0.63 FALSE
15 The Cancer Genome Atlas Prostate Adenocarcinoma INVS 0.09 0.04 enet 14 0.06 1.5e-06 5.7 5.7 1.3e-08 0.75 0.04 0.94 FALSE