[Hub]/) : Traits : Basal metabolic rate :

chr1:106,906,072-108,296,508

Best TWAS P=2.89e-08 · Best GWAS P=8e-10 conditioned to 3.74e-11

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PRMT6 0.19 0.16 lasso 6 0.16 5.4e-19 5.1 -5.2 2.6e-07 -0.08 0.59 0.41 FALSE
2 GTEx Adipose Subcutaneous PRMT6 0.17 0.10 enet 6 0.11 5.1e-09 5.0 -5.2 1.9e-07 -0.09 0.63 0.37 FALSE
3 GTEx Colon Transverse PRMT6 0.29 0.24 lasso 7 0.19 1.4e-09 5.0 -5.3 1.3e-07 -0.09 0.62 0.38 FALSE
4 GTEx Esophagus Mucosa PRMT6 0.33 0.23 lasso 7 0.29 1.4e-19 5.1 -5.2 2.3e-07 -0.08 0.61 0.39 FALSE
5 GTEx Liver PRMT6 0.60 0.52 lasso 6 0.58 1.0e-19 5.0 -5.3 1.1e-07 -0.08 0.60 0.40 FALSE
6 GTEx Muscle Skeletal PRMT6 0.32 0.16 enet 13 0.16 2.8e-15 5.1 -5.5 2.9e-08 -0.08 0.59 0.40 TRUE
7 GTEx Thyroid PRMT6 0.19 0.17 enet 14 0.19 1.7e-14 5.1 -5.3 9.3e-08 -0.08 0.61 0.39 FALSE
8 METSIM Adipose PRMT6 0.21 0.20 lasso 9 0.21 1.1e-30 5.1 -5.1 2.7e-07 -0.08 0.62 0.38 FALSE
9 The Cancer Genome Atlas Bladder Urothelial Carcinoma PRMT6 0.13 0.10 lasso 4 0.10 2.0e-08 5.1 -5.2 1.6e-07 -0.09 0.01 0.99 FALSE
10 The Cancer Genome Atlas Esophageal Carcinoma PRMT6 0.33 0.26 lasso 3 0.25 2.0e-08 5.0 -5.2 1.5e-07 -0.09 0.01 0.99 FALSE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PRMT6 0.11 0.12 enet 7 0.12 2.3e-13 5.1 -5.3 1.4e-07 -0.09 0.01 0.99 FALSE
12 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma PRMT6 0.09 0.08 blup 36 0.08 3.3e-06 5.1 -5.4 5.4e-08 -0.09 0.01 0.99 FALSE
13 The Cancer Genome Atlas Stomach Adenocarcinoma PRMT6 0.17 0.17 enet 6 0.19 1.5e-13 5.1 -5.1 3.0e-07 -0.09 0.01 0.99 FALSE