[Hub]/) : Traits : Basal metabolic rate :

chr12:27,587,038-29,432,481

Best TWAS P=1.4e-13 · Best GWAS P=4.74e-14 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CCDC91 0.08 0.06 lasso 6 0.07 9.4e-09 -6.7 5.6 2.5e-08 -0.87 0.33 0.67 FALSE
2 GTEx Artery Aorta RP11-967K21.1 0.07 0.02 lasso 7 0.01 7.9e-02 3.3 5.8 6.0e-09 -0.83 0.06 0.82 FALSE
3 GTEx Cells Transformed fibroblasts CCDC91 0.10 0.10 lasso 5 0.09 5.5e-07 -6.9 -7.1 1.7e-12 0.85 0.13 0.87 FALSE
4 GTEx Cells Transformed fibroblasts RP11-967K21.1 0.07 0.07 lasso 2 0.07 3.7e-06 -7.3 7.4 1.4e-13 -0.96 0.04 0.96 TRUE
5 GTEx Colon Transverse CCDC91 0.11 0.01 lasso 6 0.00 4.6e-01 -6.8 -5.9 3.6e-09 0.80 0.09 0.74 FALSE
6 GTEx Heart Atrial Appendage CCDC91 0.10 0.06 lasso 8 0.04 4.4e-03 -6.9 -6.4 1.3e-10 0.85 0.04 0.92 FALSE
7 GTEx Heart Atrial Appendage RP11-967K21.1 0.08 0.09 lasso 1 0.08 2.3e-04 -7.3 7.3 3.8e-13 -0.91 0.04 0.93 FALSE
8 GTEx Muscle Skeletal RP11-967K21.1 0.04 0.01 lasso 9 0.00 2.9e-01 -6.8 6.4 2.2e-10 -0.90 0.06 0.80 FALSE
9 GTEx Skin Not Sun Exposed Suprapubic CCDC91 0.26 0.05 lasso 15 0.04 4.1e-03 -7.5 -6.7 2.6e-11 0.87 0.03 0.97 FALSE
10 GTEx Skin Sun Exposed Lower leg CCDC91 0.09 0.01 enet 8 0.01 2.6e-02 -7.3 -7.1 1.6e-12 0.85 0.06 0.89 FALSE
11 The Cancer Genome Atlas Breast Invasive Carcinoma CCDC91 0.04 0.04 lasso 3 0.03 1.8e-06 -6.7 -6.7 2.3e-11 0.94 0.18 0.82 FALSE
12 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CCDC91 0.06 0.02 blup 174 0.04 2.9e-05 2.4 -5.4 6.0e-08 0.79 0.42 0.55 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma CCDC91 0.09 0.01 blup 170 0.02 1.0e-03 -7.0 -5.2 2.6e-07 0.75 0.18 0.68 FALSE
14 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CCDC91 0.09 0.11 lasso 2 0.12 2.3e-05 -6.8 -6.8 1.1e-11 0.91 0.07 0.91 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma CCDC91 0.40 0.12 blup 175 0.14 4.9e-13 -7.0 -6.4 2.0e-10 0.72 0.09 0.91 FALSE