Best TWAS P=2.05e-09 · Best GWAS P=6.06e-08 conditioned to 2.38e-07
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | C1orf54 | 0.06 | 0.02 | enet | 13 | 0.02 | 1.2e-05 | 4.6 | -6.0 | 2.1e-09 | -0.04 | 0.00 | 0.86 | TRUE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | MRPS21 | 0.13 | 0.13 | enet | 10 | 0.13 | 1.7e-14 | -3.9 | 5.2 | 2.5e-07 | 0.21 | 0.02 | 0.71 | FALSE |