TWAS
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Usage
Models
Genes
Traits
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Traits
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Basal metabolic rate
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chr1:150,000,165-150,515,021
Best TWAS P=2.05e-09 · Best GWAS P=6.06e-08 conditioned to 2.38e-07
150M
150.1M
150.2M
150.3M
150.4M
150.5M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Breast Invasive Carcinoma
C1orf54
0.06
0.02
enet
13
0.02
1.2e-05
4.6
-6.0
2.1e-09
-0.04
0.00
0.86
TRUE
2
The Cancer Genome Atlas
Brain Lower Grade Glioma
MRPS21
0.13
0.13
enet
10
0.13
1.7e-14
-3.9
5.2
2.5e-07
0.21
0.02
0.71
FALSE