Best TWAS P=1.18e-14 · Best GWAS P=9.34e-15 conditioned to 0.0639
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | EDNRB | 0.05 | 0.03 | bslmm | 465 | 0.04 | 3.1e-06 | -6.2 | 6.6 | 4.3e-11 | -0.61 | 0.4 | 0.58 | FALSE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | EDNRB | 0.02 | 0.00 | blup | 60 | 0.00 | 3.1e-02 | -7.7 | 7.7 | 1.2e-14 | -0.90 | 0.0 | 0.72 | TRUE |