[Hub]/) : Traits : Basal metabolic rate : ← →

chr3:87,404,256-88,911,119

Best TWAS P=6.84e-13 · Best GWAS P=5.68e-13 conditioned to 0.961

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Cells Transformed fibroblasts	ZNF654	0.08	0.09	enet	6	0.10	3.1e-08	-7.2	-7.2	6.8e-13	0.57	0.00	1.00	TRUE
6	GTEx	Heart Atrial Appendage	CGGBP1	0.25	0.15	enet	30	0.16	1.5e-07	-3.3	-5.2	1.5e-07	0.60	0.25	0.54	TRUE
1	CommonMind	Brain Pre-frontal Cortex	C3orf38	0.08	0.00	enet	14	0.04	2.3e-05	-6.0	-7.0	2.9e-12	0.56	0.06	0.90	FALSE
5	GTEx	Esophagus Mucosa	C3orf38	0.11	0.06	lasso	7	0.07	1.5e-05	-6.1	6.8	1.4e-11	-0.67	0.10	0.90	FALSE
7	GTEx	Nerve Tibial	C3orf38	0.09	0.05	lasso	4	0.04	6.3e-04	-6.1	6.2	5.7e-10	-0.68	0.48	0.36	FALSE
3	GTEx	Artery Aorta	C3orf38	0.06	0.06	lasso	7	0.05	6.0e-04	-6.1	6.2	7.4e-10	-0.67	0.44	0.36	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	ZNF654	0.03	0.04	lasso	3	0.03	4.6e-04	-6.0	-6.1	9.8e-10	0.69	0.15	0.55	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C3orf38	0.02	0.03	lasso	1	0.03	1.9e-04	-6.0	6.0	1.8e-09	-0.69	0.05	0.45	FALSE
16	The Cancer Genome Atlas	Prostate Adenocarcinoma	C3orf38	0.03	0.05	lasso	1	0.05	8.1e-06	-6.0	6.0	1.8e-09	-0.69	0.41	0.49	FALSE
17	The Cancer Genome Atlas	Thyroid Carcinoma	CGGBP1	0.30	0.07	enet	11	0.09	2.3e-09	-7.2	-6.0	2.0e-09	0.80	0.00	1.00	FALSE
11	GTEx	Thyroid	C3orf38	0.12	0.08	lasso	18	0.07	1.0e-05	-5.9	6.0	2.1e-09	-0.68	0.85	0.13	FALSE
14	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C3orf38	0.02	0.01	blup	24	0.02	2.0e-03	-6.0	6.0	2.7e-09	-0.65	0.06	0.21	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	C3orf38	0.01	0.01	lasso	3	0.01	1.2e-03	-6.0	5.9	4.2e-09	-0.65	0.04	0.30	FALSE
2	GTEx	Adipose Visceral Omentum	C3orf38	0.09	0.00	lasso	5	0.00	5.2e-01	-2.7	5.8	5.4e-09	-0.51	0.04	0.30	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	C3orf38	0.09	0.07	lasso	6	0.04	2.8e-03	-5.9	5.8	7.2e-09	-0.68	0.36	0.22	FALSE
10	GTEx	Testis	C3orf38	0.11	0.01	enet	12	0.00	1.9e-01	-5.6	5.6	1.8e-08	-0.72	0.12	0.22	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	ZNF654	0.09	0.01	lasso	7	0.06	2.7e-04	-6.2	-5.5	2.9e-08	0.64	0.10	0.26	FALSE
12	GTEx	Uterus	ZNF654	0.29	-0.01	lasso	4	0.01	1.7e-01	-6.1	-5.3	1.0e-07	0.66	0.09	0.19	FALSE