TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Basal metabolic rate
:
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chr3:84,317,575-86,808,226
Best TWAS P=7.01e-19 · Best GWAS P=3.34e-19 conditioned to 0.00272
84.5M
85M
85.5M
86M
86.5M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
CADM2
0.05
0.03
lasso
3
0.04
5.0e-05
8.5
8.9
7.0e-19
0.81
0.11
0.88
TRUE
3
The Cancer Genome Atlas
Lung Adenocarcinoma
CADM2
0.08
0.04
lasso
4
0.05
2.1e-06
8.6
8.8
1.5e-18
0.77
0.17
0.83
FALSE
1
METSIM
Adipose
CADM2
0.05
0.06
lasso
10
0.06
1.3e-09
6.8
7.6
2.7e-14
0.63
0.90
0.10
FALSE
2
The Cancer Genome Atlas
Brain Lower Grade Glioma
CADM2
0.06
0.00
blup
339
0.00
2.7e-01
-5.5
-6.5
1.0e-10
-0.39
0.06
0.15
FALSE
5
The Cancer Genome Atlas
Pheochromocytoma and Paraganglioma
CADM2
0.14
0.05
blup
339
0.09
2.7e-04
8.3
5.4
7.5e-08
0.76
0.11
0.54
FALSE