TWAS
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Models
Genes
Traits
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Traits
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Basal metabolic rate
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chr4:37,930,312-39,985,082
Best TWAS P=3.54e-08 · Best GWAS P=7.93e-07 conditioned to 0.0151
38M
38.5M
39M
39.5M
40M
0
1
2
3
4
5
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
METSIM
Adipose
WDR19
0.04
0.01
enet
20
0.02
0.00077
-4.8
5.5
3.5e-08
0.51
0.05
0.92
TRUE
1
GTEx
Vagina
AC021860.1
0.42
0.04
lasso
12
0.07
0.01220
3.9
5.5
4.5e-08
0.01
0.02
0.10
TRUE
3
ROSMAP
Brain Pre-frontal Cortex
WDR19
0.02
0.02
enet
9
0.02
0.00277
4.9
5.1
3.1e-07
0.99
0.03
0.90
FALSE