Best TWAS P=3.54e-08 · Best GWAS P=7.93e-07 conditioned to 0.0151
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Vagina | AC021860.1 | 0.42 | 0.04 | lasso | 12 | 0.07 | 0.01220 | 3.9 | 5.5 | 4.5e-08 | 0.01 | 0.02 | 0.10 | TRUE |
2 | METSIM | Adipose | WDR19 | 0.04 | 0.01 | enet | 20 | 0.02 | 0.00077 | -4.8 | 5.5 | 3.5e-08 | 0.51 | 0.05 | 0.92 | TRUE |
3 | ROSMAP | Brain Pre-frontal Cortex | WDR19 | 0.02 | 0.02 | enet | 9 | 0.02 | 0.00277 | 4.9 | 5.1 | 3.1e-07 | 0.99 | 0.03 | 0.90 | FALSE |