[Hub]/) : Traits : Basal metabolic rate :

chr5:35,407,342-38,450,430

Best TWAS P=3.89e-13 · Best GWAS P=5.91e-17 conditioned to 8.66e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C5orf42 0.04 0.03 lasso 4 0.04 1.2e-05 -6.5 5.7 1.5e-08 -0.65 0.40 0.48 FALSE
2 GTEx Cells Transformed fibroblasts WDR70 0.06 0.03 lasso 8 0.03 3.5e-03 -6.1 6.6 4.0e-11 -0.72 0.38 0.42 FALSE
3 GTEx Esophagus Muscularis LMBRD2 0.13 0.07 enet 21 0.08 1.8e-05 3.8 -5.3 9.9e-08 -0.04 0.28 0.05 TRUE
4 GTEx Nerve Tibial WDR70 0.17 0.07 lasso 3 0.05 1.4e-04 5.9 5.7 1.2e-08 -0.43 0.40 0.03 FALSE
5 GTEx Whole Blood NUP155 0.05 0.01 enet 14 0.04 1.1e-04 -8.4 5.5 4.4e-08 -0.61 0.00 0.95 FALSE
6 GTEx Whole Blood C5orf42 0.07 0.00 enet 16 0.01 1.8e-02 -8.4 6.2 6.7e-10 -0.68 0.01 0.88 FALSE
7 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C5orf42 0.04 0.05 lasso 3 0.04 1.1e-03 -7.5 7.3 3.9e-13 -0.92 0.00 0.94 TRUE