Best TWAS P=2.26e-09 · Best GWAS P=4.23e-13 conditioned to 4.01e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | ABO | 0.08 | 0.01 | blup | 43 | 0.07 | 7.9e-07 | 3.7 | 5.6 | 2.8e-08 | 0.72 | 0.03 | 0.95 | FALSE |
2 | The Cancer Genome Atlas | Glioblastoma Multiforme | ABO | 0.18 | 0.01 | blup | 42 | 0.07 | 3.0e-03 | 3.6 | 5.3 | 1.3e-07 | 0.76 | 0.01 | 0.47 | FALSE |
3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | ABO | 0.11 | 0.08 | blup | 43 | 0.12 | 2.5e-13 | 3.6 | 6.0 | 2.3e-09 | 0.80 | 0.58 | 0.42 | TRUE |
4 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | ABO | 0.23 | 0.21 | lasso | 5 | 0.20 | 6.7e-09 | 4.1 | 5.3 | 1.2e-07 | 0.61 | 0.60 | 0.40 | FALSE |
5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ABO | 0.18 | 0.15 | blup | 43 | 0.21 | 3.4e-21 | 4.1 | 5.9 | 3.1e-09 | 0.82 | 0.39 | 0.61 | FALSE |
6 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | ABO | 0.38 | 0.11 | blup | 43 | 0.15 | 9.6e-05 | 7.1 | 5.7 | 1.2e-08 | 0.82 | 0.01 | 0.93 | FALSE |
7 | The Cancer Genome Atlas | Stomach Adenocarcinoma | ABO | 0.20 | 0.10 | blup | 42 | 0.18 | 5.8e-13 | 3.7 | 5.4 | 5.8e-08 | 0.78 | 0.98 | 0.02 | FALSE |