Best TWAS P=4.31e-12 · Best GWAS P=9.13e-13 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | KCTD15 | 0.08 | 0.06 | lasso | 4 | 0.05 | 2.9e-08 | 5.3 | 5.4 | 8.4e-08 | 0.47 | 0.99 | 0.01 | FALSE |
2 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | KCTD15 | 0.25 | 0.05 | lasso | 4 | 0.04 | 3.3e-02 | 7.1 | 6.9 | 4.3e-12 | 0.95 | 0.00 | 0.93 | TRUE |