Best TWAS P=4.09e-09 · Best GWAS P=1.16e-10 conditioned to 0.00107
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | FBLN1 | 0.09 | 0.04 | lasso | 9 | 0.06 | 2.4e-05 | 6.4 | -5.5 | 4.2e-08 | -0.93 | 0.00 | 0.98 | FALSE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | RIBC2 | 0.03 | 0.01 | blup | 59 | 0.03 | 1.8e-04 | -3.8 | -5.5 | 4.9e-08 | -0.63 | 0.04 | 0.93 | FALSE |
3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | RIBC2 | 0.11 | 0.02 | blup | 58 | 0.09 | 2.0e-04 | -3.6 | -5.9 | 4.1e-09 | -0.70 | 0.06 | 0.56 | TRUE |