Best TWAS P=5.85e-08 · Best GWAS P=5.48e-08 conditioned to 0.119
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adrenal Gland | RIF1 | 0.14 | 0.04 | lasso | 2 | 0.05 | 6.4e-03 | 4.8 | -5.1 | 2.7e-07 | -0.75 | 0.06 | 0.60 | FALSE |
2 | GTEx | Artery Coronary | RIF1 | 0.28 | 0.09 | lasso | 6 | 0.09 | 6.8e-04 | 4.8 | -5.1 | 2.8e-07 | -0.74 | 0.05 | 0.89 | FALSE |
3 | GTEx | Colon Transverse | RIF1 | 0.20 | 0.04 | lasso | 7 | 0.06 | 7.5e-04 | 5.4 | -5.4 | 5.9e-08 | -0.85 | 0.02 | 0.97 | TRUE |
4 | GTEx | Lung | RIF1 | 0.15 | 0.12 | lasso | 2 | 0.17 | 4.0e-13 | 4.8 | -5.2 | 2.6e-07 | -0.70 | 0.11 | 0.88 | FALSE |
5 | GTEx | Skin Not Sun Exposed Suprapubic | RIF1 | 0.37 | 0.34 | enet | 26 | 0.39 | 5.5e-23 | -4.1 | -5.2 | 1.6e-07 | -0.66 | 0.56 | 0.37 | FALSE |
6 | METSIM | Adipose | RIF1 | 0.04 | 0.04 | lasso | 7 | 0.03 | 2.2e-05 | 4.8 | -5.4 | 6.3e-08 | -0.94 | 0.01 | 0.98 | FALSE |