[Hub]/) : Traits : Impedance of leg (right) : ← →

chr9:110,932,294-112,472,083

Best TWAS P=4.87e-14 · Best GWAS P=1.82e-10 conditioned to 0.653

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	CTNNAL1	0.09	0.00	blup	83	0.04	1.0e-04	-4.3	-7.5	4.9e-14	-0.47	0.02	0.48	TRUE
16	GTEx	Pancreas	CTNNAL1	0.41	0.18	lasso	9	0.19	2.6e-08	5.6	-7.3	3.6e-13	-0.85	0.09	0.91	TRUE
24	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CTNNAL1	0.21	0.02	lasso	3	0.06	2.1e-03	5.6	-6.9	4.4e-12	-0.72	0.01	0.85	FALSE
14	GTEx	Muscle Skeletal	CTNNAL1	0.42	0.14	lasso	7	0.27	7.6e-27	-4.3	-6.8	1.0e-11	-0.63	0.92	0.07	FALSE
6	GTEx	Artery Aorta	CTNNAL1	0.17	0.06	lasso	6	0.05	9.5e-04	-4.3	-6.8	1.4e-11	-0.48	0.18	0.58	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CTNNAL1	0.10	0.00	lasso	7	0.06	1.3e-07	-4.3	-6.6	3.7e-11	-0.63	0.39	0.58	FALSE
12	GTEx	Esophagus Muscularis	IKBKAP	0.16	0.14	lasso	7	0.11	4.8e-07	6.4	6.6	4.1e-11	0.98	0.00	1.00	FALSE
15	GTEx	Nerve Tibial	IKBKAP	0.13	0.16	lasso	7	0.14	3.7e-10	6.4	6.5	7.3e-11	0.99	0.00	1.00	FALSE
13	GTEx	Lung	IKBKAP	0.11	0.11	lasso	5	0.10	1.9e-08	6.4	6.5	9.8e-11	0.99	0.00	1.00	FALSE
5	GTEx	Artery Aorta	IKBKAP	0.15	0.14	lasso	4	0.15	1.9e-08	6.4	6.3	2.2e-10	0.97	0.00	1.00	FALSE
8	GTEx	Artery Tibial	CTNNAL1	0.37	0.18	lasso	6	0.31	9.9e-25	5.6	-6.2	6.0e-10	-0.72	0.08	0.92	FALSE
21	METSIM	Adipose	IKBKAP	0.08	0.01	blup	648	0.03	1.7e-05	6.4	6.1	8.4e-10	0.58	0.01	0.99	FALSE
2	GTEx	Adipose Subcutaneous	IKBKAP	0.08	0.08	lasso	4	0.07	4.6e-06	6.4	6.1	1.0e-09	1.00	0.00	1.00	FALSE
19	GTEx	Spleen	CTNNAL1	0.66	0.06	enet	84	0.18	2.8e-05	5.6	-6.1	1.0e-09	-0.50	0.02	0.90	FALSE
3	GTEx	Adipose Subcutaneous	CTNNAL1	0.22	0.20	enet	14	0.22	7.1e-18	5.3	-6.0	1.7e-09	-0.89	0.34	0.66	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CTNNAL1	0.29	0.06	enet	12	0.12	8.8e-14	5.6	-6.0	2.2e-09	-0.72	0.06	0.94	FALSE
17	GTEx	Pituitary	IKBKAP	0.29	0.24	lasso	9	0.23	2.0e-06	6.4	5.9	2.9e-09	0.93	0.00	0.98	FALSE
18	GTEx	Skin Sun Exposed Lower leg	CTNNAL1	0.12	0.09	lasso	5	0.09	1.2e-07	5.6	-5.9	3.7e-09	-0.96	0.01	0.99	FALSE
20	GTEx	Whole Blood	CTNNAL1	0.14	0.07	lasso	6	0.07	9.4e-07	-4.3	-5.8	8.8e-09	-0.05	0.49	0.32	FALSE
11	GTEx	Cells Transformed fibroblasts	CTNNAL1	0.22	0.08	enet	21	0.19	2.1e-14	5.6	-5.7	1.2e-08	-0.70	0.04	0.96	FALSE
22	YFS	Blood	CTNNAL1	0.15	0.07	enet	29	0.08	2.8e-26	-4.3	-5.6	1.9e-08	-0.17	0.99	0.01	FALSE
4	GTEx	Adipose Visceral Omentum	CTNNAL1	0.20	0.16	lasso	7	0.15	2.6e-08	5.3	-5.6	2.3e-08	-0.92	0.11	0.89	FALSE
10	GTEx	Cells Transformed fibroblasts	IKBKAP	0.20	0.19	lasso	5	0.18	1.0e-13	6.4	5.5	2.9e-08	0.99	0.00	1.00	FALSE
9	GTEx	Breast Mammary Tissue (Male)	CTNNAL1	0.20	-0.01	lasso	4	-0.01	5.9e-01	4.0	-5.3	1.1e-07	-0.67	0.03	0.62	FALSE
7	GTEx	Artery Tibial	IKBKAP	0.13	0.12	enet	11	0.13	2.0e-10	3.2	5.3	1.4e-07	0.67	0.33	0.67	FALSE