[Hub]/) : Traits : Impedance of leg (right) :

chr9:110,932,294-112,472,083

Best TWAS P=4.87e-14 · Best GWAS P=1.82e-10 conditioned to 0.653

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CTNNAL1 0.10 0.00 lasso 7 0.06 1.3e-07 -4.3 -6.6 3.7e-11 -0.63 0.39 0.58 FALSE
2 GTEx Adipose Subcutaneous IKBKAP 0.08 0.08 lasso 4 0.07 4.6e-06 6.4 6.1 1.0e-09 1.00 0.00 1.00 FALSE
3 GTEx Adipose Subcutaneous CTNNAL1 0.22 0.20 enet 14 0.22 7.1e-18 5.3 -6.0 1.7e-09 -0.89 0.34 0.66 FALSE
4 GTEx Adipose Visceral Omentum CTNNAL1 0.20 0.16 lasso 7 0.15 2.6e-08 5.3 -5.6 2.3e-08 -0.92 0.11 0.89 FALSE
5 GTEx Artery Aorta IKBKAP 0.15 0.14 lasso 4 0.15 1.9e-08 6.4 6.3 2.2e-10 0.97 0.00 1.00 FALSE
6 GTEx Artery Aorta CTNNAL1 0.17 0.06 lasso 6 0.05 9.5e-04 -4.3 -6.8 1.4e-11 -0.48 0.18 0.58 FALSE
7 GTEx Artery Tibial IKBKAP 0.13 0.12 enet 11 0.13 2.0e-10 3.2 5.3 1.4e-07 0.67 0.33 0.67 FALSE
8 GTEx Artery Tibial CTNNAL1 0.37 0.18 lasso 6 0.31 9.9e-25 5.6 -6.2 6.0e-10 -0.72 0.08 0.92 FALSE
9 GTEx Breast Mammary Tissue (Male) CTNNAL1 0.20 -0.01 lasso 4 -0.01 5.9e-01 4.0 -5.3 1.1e-07 -0.67 0.03 0.62 FALSE
10 GTEx Cells Transformed fibroblasts IKBKAP 0.20 0.19 lasso 5 0.18 1.0e-13 6.4 5.5 2.9e-08 0.99 0.00 1.00 FALSE
11 GTEx Cells Transformed fibroblasts CTNNAL1 0.22 0.08 enet 21 0.19 2.1e-14 5.6 -5.7 1.2e-08 -0.70 0.04 0.96 FALSE
12 GTEx Esophagus Muscularis IKBKAP 0.16 0.14 lasso 7 0.11 4.8e-07 6.4 6.6 4.1e-11 0.98 0.00 1.00 FALSE
13 GTEx Lung IKBKAP 0.11 0.11 lasso 5 0.10 1.9e-08 6.4 6.5 9.8e-11 0.99 0.00 1.00 FALSE
14 GTEx Muscle Skeletal CTNNAL1 0.42 0.14 lasso 7 0.27 7.6e-27 -4.3 -6.8 1.0e-11 -0.63 0.92 0.07 FALSE
15 GTEx Nerve Tibial IKBKAP 0.13 0.16 lasso 7 0.14 3.7e-10 6.4 6.5 7.3e-11 0.99 0.00 1.00 FALSE
16 GTEx Pancreas CTNNAL1 0.41 0.18 lasso 9 0.19 2.6e-08 5.6 -7.3 3.6e-13 -0.85 0.09 0.91 TRUE
17 GTEx Pituitary IKBKAP 0.29 0.24 lasso 9 0.23 2.0e-06 6.4 5.9 2.9e-09 0.93 0.00 0.98 FALSE
18 GTEx Skin Sun Exposed Lower leg CTNNAL1 0.12 0.09 lasso 5 0.09 1.2e-07 5.6 -5.9 3.7e-09 -0.96 0.01 0.99 FALSE
19 GTEx Spleen CTNNAL1 0.66 0.06 enet 84 0.18 2.8e-05 5.6 -6.1 1.0e-09 -0.50 0.02 0.90 FALSE
20 GTEx Whole Blood CTNNAL1 0.14 0.07 lasso 6 0.07 9.4e-07 -4.3 -5.8 8.8e-09 -0.05 0.49 0.32 FALSE
21 METSIM Adipose IKBKAP 0.08 0.01 blup 648 0.03 1.7e-05 6.4 6.1 8.4e-10 0.58 0.01 0.99 FALSE
22 YFS Blood CTNNAL1 0.15 0.07 enet 29 0.08 2.8e-26 -4.3 -5.6 1.9e-08 -0.17 0.99 0.01 FALSE
23 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CTNNAL1 0.29 0.06 enet 12 0.12 8.8e-14 5.6 -6.0 2.2e-09 -0.72 0.06 0.94 FALSE
24 The Cancer Genome Atlas Pancreatic Adenocarcinoma CTNNAL1 0.21 0.02 lasso 3 0.06 2.1e-03 5.6 -6.9 4.4e-12 -0.72 0.01 0.85 FALSE
25 The Cancer Genome Atlas Prostate Adenocarcinoma CTNNAL1 0.09 0.00 blup 83 0.04 1.0e-04 -4.3 -7.5 4.9e-14 -0.47 0.02 0.48 TRUE