TWAS hub - CTNNAL1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1030	0.0300	2.3e-05	0.002	0.029	0.047	0.043	0.058	1.8e-01	1.5e-04	2.0e-06	5.5e-06	1.3e-07
2	GTEx	Adipose Subcutaneous	0.2160	0.0460	4.8e-10	0.198	NA	0.220	NA	0.210	4.8e-16	NA	7.1e-18	NA	4.8e-17
3	GTEx	Adipose Visceral Omentum	0.2040	0.0590	1.5e-04	0.164	NA	0.148	NA	0.152	7.4e-09	NA	4.1e-08	NA	2.6e-08
4	GTEx	Artery Aorta	0.1720	0.0560	6.9e-04	0.063	NA	0.037	NA	0.050	2.3e-04	NA	3.9e-03	NA	9.5e-04
5	GTEx	Artery Tibial	0.3745	0.0545	2.8e-16	0.176	NA	0.305	NA	0.310	1.0e-13	NA	2.9e-24	NA	9.9e-25
6	GTEx	Breast Mammary Tissue	0.1210	0.0490	4.8e-03	0.036	NA	0.044	NA	0.046	5.9e-03	NA	2.6e-03	NA	2.2e-03
7	GTEx	Breast Mammary Tissue (Male)	0.1955	0.1215	8.6e-02	-0.008	NA	-0.013	NA	-0.009	5.3e-01	NA	9.3e-01	NA	5.9e-01
8	GTEx	Cells Transformed fibroblasts	0.2240	0.0550	1.7e-06	0.077	NA	0.193	NA	0.192	2.1e-06	NA	2.1e-14	NA	2.3e-14
9	GTEx	Esophagus Muscularis	0.1580	0.0460	8.7e-05	0.052	NA	0.037	NA	0.024	4.2e-04	NA	2.4e-03	NA	1.2e-02
10	GTEx	Muscle Skeletal	0.4179	0.0536	5.6e-17	0.140	NA	0.259	NA	0.273	1.2e-13	NA	2.3e-25	NA	7.6e-27
11	GTEx	Nerve Tibial	0.2990	0.0579	2.1e-10	0.121	NA	0.151	NA	0.198	7.3e-09	NA	7.6e-11	NA	4.8e-14
12	GTEx	Pancreas	0.4090	0.0750	3.1e-07	0.181	NA	0.156	NA	0.186	4.1e-08	NA	4.0e-07	NA	2.6e-08
13	GTEx	Skin Sun Exposed Lower leg	0.1250	0.0350	2.4e-05	0.093	NA	0.063	NA	0.086	4.2e-08	NA	6.4e-06	NA	1.2e-07
14	GTEx	Spleen	0.6600	0.1160	1.1e-05	0.060	NA	0.176	NA	0.174	1.2e-02	NA	2.8e-05	NA	3.2e-05
15	GTEx	Thyroid	0.1570	0.0560	1.5e-03	-0.001	NA	0.030	NA	0.012	4.4e-01	NA	2.2e-03	NA	3.5e-02
16	GTEx	Whole Blood	0.1440	0.0440	2.9e-04	0.066	NA	0.052	NA	0.067	9.6e-07	NA	1.4e-05	NA	9.4e-07
17	METSIM	Adipose	0.1625	0.0400	2.7e-12	0.079	0.091	0.121	0.104	0.106	7.6e-12	1.5e-13	1.2e-17	2.5e-15	1.5e-15
18	NTR	Blood	0.0319	0.0110	1.7e-04	0.025	0.008	0.026	0.018	0.030	1.2e-08	8.5e-04	7.4e-09	9.6e-07	5.3e-10
19	YFS	Blood	0.1491	0.0321	4.6e-13	0.070	0.057	0.085	0.078	0.083	6.3e-22	5.9e-18	2.8e-26	2.7e-24	8.5e-26
20	TCGA	Kidney Renal Clear Cell Carcinoma	0.2857	0.0737	1.7e-13	0.059	0.118	0.124	NA	0.123	3.4e-07	3.8e-13	8.8e-14	NA	9.3e-14
21	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0690	0.0440	6.8e-03	0.025	0.024	0.031	NA	0.037	1.3e-02	1.5e-02	6.9e-03	NA	3.4e-03
22	TCGA	Pancreatic Adenocarcinoma	0.2120	0.1020	5.7e-03	0.022	0.009	0.022	NA	0.057	4.1e-02	1.3e-01	4.0e-02	NA	2.1e-03
23	TCGA	Prostate Adenocarcinoma	0.0933	0.0398	1.8e-04	0.003	0.036	0.016	NA	0.012	1.5e-01	1.0e-04	7.0e-03	NA	1.7e-02
24	TCGA	Thyroid Carcinoma	0.1110	0.0460	1.2e-07	0.046	0.079	0.058	NA	0.056	2.4e-05	4.0e-08	2.5e-06	NA	3.8e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Impedance of leg (right)	6.7	32.6	56.8	-6.6	-6.0	-5.6	-6.8	-6.2	-2.1	-5.3	-5.7	-4.4	-6.8	-4.8	-7.3	-5.9	-6.1	-4.7	-5.8	-4.5	-4.8	-5.6	-6.0	-5.0	-6.9	-7.5	-3.7
Myopia	6.6	9.5	16.4	3.9	3.8	3.3	3.6	2.8	1.1	2.4	3.4	2.9	4.1	2.8	3.4	3.3	2.8	2.3	1.9	3.1	2.6	3.1	3.3	3.2	4.0	3.4	1.9
Impedance of leg (left)	5.2	25.4	47.5	-5.8	-5.3	-4.9	-5.8	-5.1	-1.8	-5.3	-5.1	-3.3	-6.0	-4.0	-6.4	-5.3	-5.3	-3.8	-5.2	-3.8	-3.9	-5.3	-5.5	-4.7	-6.1	-6.9	-3.4
Impedance of whole body	4.6	23.6	50.2	-5.8	-4.9	-4.3	-5.8	-4.6	-1.1	-4.2	-5.1	-2.8	-5.9	-3.0	-5.8	-4.7	-4.9	-3.0	-5.4	-3.7	-4.4	-5.3	-5.6	-4.9	-6.0	-7.1	-4.2
Illnesses of father: High blood pressure	3.7	4.6	9.6	-2.5	-3.1	-2.8	-1.9	-2.1	-1.8	-1.1	-2.7	-1.9	-2.5	-1.8	-2.2	-2.7	-1.6	-2.1	-0.2	-2.1	-1.1	-1.2	-2.8	-2.2	-2.6	-1.9	-2.4
Medication for hormone replacement therapy	3.5	3.9	9.4	2.2	1.9	1.5	2.6	1.7	0.0	1.2	2.2	0.2	2.4	1.2	1.9	1.6	1.1	3.1	2.3	1.8	1.4	2.8	2.2	1.9	2.4	2.7	1.9
Impedance of arm (right)	3.5	16.4	34.1	-5.1	-3.9	-3.1	-4.7	-3.0	0.2	-3.5	-4.5	-1.2	-5.0	-1.3	-4.3	-3.5	-4.5	-2.1	-4.8	-3.8	-3.4	-4.5	-5.0	-4.9	-5.1	-5.8	-4.3
Impedance of arm (left)	3.5	16.0	36.0	-5.0	-3.9	-3.3	-4.9	-3.3	-0.0	-2.8	-4.2	-1.9	-4.8	-1.7	-4.6	-3.6	-4.3	-2.2	-4.5	-3.2	-3.6	-4.4	-4.9	-4.4	-5.0	-6.0	-4.2
Time employed in main current job	3.4	3.9	6.5	2.5	2.4	2.0	2.2	2.0	2.5	0.7	2.3	2.0	2.5	1.8	2.6	1.9	0.2	1.6	1.5	1.2	1.3	2.4	2.1	1.8	2.5	2.0	1.1
Number of incorrect matches in round	3.3	5.6	12.4	2.4	2.6	2.8	2.6	2.9	-0.1	2.5	2.4	1.5	2.6	2.5	2.6	2.9	3.5	1.0	1.3	2.4	0.5	1.4	2.7	1.6	2.7	3.1	2.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.3	3.8	7.3	-2.4	-2.6	-2.4	-2.2	-1.8	-2.0	-2.0	-2.1	-1.9	-2.4	-2.5	-2.7	-2.4	-1.2	-2.6	-1.1	-1.7	0.2	-0.9	-1.8	-1.3	-2.3	-1.0	-0.3
Intelligence (Savage-Jansen 2018)	3.1	9.6	25.9	-3.0	-3.1	-3.5	-4.3	-5.1	-2.9	-1.9	-2.9	-3.4	-3.3	-4.8	-2.9	-3.2	-3.7	-1.3	-1.7	-0.1	-2.9	-1.6	-2.7	-0.9	-3.4	-4.4	-1.1
Medication: Allopurinol	3.1	4.1	8.9	-2.4	-3.0	-3.0	-1.2	-2.5	-0.9	-1.8	-2.6	-1.8	-2.0	-2.3	-2.9	-2.5	-1.5	-2.2	-0.0	-2.5	0.2	-1.1	-2.4	-1.7	-2.4	-0.4	-1.1
Age when periods started (menarche)	3.0	7.2	35.8	-2.1	-3.7	-3.5	0.8	-0.2	-0.7	-2.7	-2.8	-1.6	-1.6	-0.4	-3.7	-3.8	-0.8	1.5	0.8	-6.0	2.8	1.1	-3.5	-2.4	-2.4	1.2	-4.3
Had menopause	3.0	3.7	10.4	2.7	1.4	0.4	2.5	0.8	-0.2	-0.5	2.2	-0.2	2.6	-0.6	1.4	0.6	0.4	1.9	3.0	2.1	2.1	2.7	2.7	3.2	2.5	1.8	1.8
Heel bone mineral density (BMD) T-score, automated (right)	2.9	6.6	14.2	3.7	2.6	2.1	3.3	2.6	0.7	1.6	3.3	0.7	3.8	1.3	2.6	1.9	1.0	2.4	2.4	2.1	1.9	3.0	3.4	3.3	3.5	2.6	1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	2.8	3.7	8.6	-2.8	-2.4	-1.7	-2.2	-1.2	-1.6	-1.1	-2.9	-1.6	-2.7	-0.9	-1.9	-1.5	-0.4	-1.2	-1.7	-2.0	-1.0	-2.4	-2.0	-2.8	-2.7	-1.0	-1.4
Heel bone mineral density (BMD) T-score, automated (left)	2.8	6.3	13.2	3.5	2.7	2.4	3.1	2.6	0.6	1.3	3.2	0.5	3.6	1.6	2.8	2.1	1.1	2.4	1.9	2.2	1.6	2.7	3.4	3.0	3.4	3.0	1.7
Medication: Ramipril	2.8	3.6	7.1	-2.2	-2.3	-2.2	-1.9	-1.6	-0.2	-2.4	-2.1	-0.7	-2.1	-1.3	-2.5	-2.2	-1.3	-2.5	-1.5	-2.7	-0.3	-1.3	-2.2	-1.8	-2.2	-1.8	-1.4
Wears glasses or contact lenses	2.7	3.1	7.8	2.0	2.3	1.9	1.2	1.4	0.8	0.4	2.8	0.9	2.1	0.3	2.1	1.7	0.7	1.1	1.0	2.6	0.1	1.1	2.8	2.5	2.2	0.7	2.7
Leg fat-free mass (right)	2.5	13.1	41.9	3.7	2.7	2.7	4.8	4.0	0.0	3.0	2.7	2.9	4.1	3.1	3.5	2.9	5.2	3.5	4.8	0.6	4.5	4.6	2.8	2.6	3.8	6.5	1.1
Leg predicted mass (right)	2.5	13.2	42.7	3.7	2.8	2.8	4.8	4.1	0.1	3.1	2.7	2.9	4.1	3.2	3.5	2.9	5.2	3.4	4.8	0.6	4.6	4.5	2.7	2.5	3.9	6.5	1.1
Cholesterol lowering medication	2.5	3.7	13.0	2.0	1.3	1.0	2.8	2.1	0.9	0.5	1.4	1.7	2.2	1.5	1.3	0.8	2.8	0.9	2.8	-0.1	2.8	3.0	1.5	1.3	2.0	3.6	0.7
Schizophrenia vs Biploar Disorder	2.4	3.1	10.2	-2.1	-2.4	-2.0	-1.4	-1.1	-1.7	-1.0	-2.3	-1.0	-1.8	-0.3	-2.4	-1.7	-0.4	-0.1	-1.1	-3.2	-0.5	-0.9	-2.7	-2.1	-2.1	-0.6	-2.3
Maternal smoking around birth	2.4	3.5	11.5	-2.1	-2.1	-1.2	-0.9	0.4	-3.4	-1.6	-2.5	0.4	-1.9	1.0	-1.5	-1.4	2.2	-0.9	-1.1	-2.8	-0.6	-1.3	-2.5	-3.1	-2.1	0.3	-2.7
Exposure to tobacco smoke at home	2.4	2.7	8.3	0.9	2.2	2.5	-0.4	1.1	2.4	1.4	1.3	0.9	0.7	0.7	1.8	2.8	-0.9	0.1	-1.4	2.9	-1.8	-0.9	2.5	0.7	1.1	-0.6	2.5
Fractured/broken bones in last 5 years	2.4	3.0	11.4	-2.0	-2.1	-1.8	-0.7	-1.0	-3.4	-1.5	-2.3	-2.3	-1.7	-0.6	-2.5	-1.7	1.2	-0.6	-0.8	-2.3	-0.0	-0.7	-1.8	-2.1	-2.0	-0.3	-1.8
Qualifications: None of the above	2.3	5.0	26.6	-2.2	-2.8	-2.3	-0.2	0.1	-1.1	-2.6	-3.0	-0.9	-2.1	0.1	-3.0	-2.6	1.2	-1.2	-0.5	-5.2	1.5	-0.8	-2.9	-2.8	-2.3	-0.2	-3.2
Seen doctor (GP) for nerves, anxiety, tension or depression	2.3	3.5	7.4	-2.4	-2.2	-1.8	-1.7	-1.3	-1.8	-2.0	-2.3	-1.1	-2.5	-1.1	-1.9	-2.0	-1.0	0.8	-1.3	-1.6	-1.8	-1.8	-1.9	-1.9	-2.4	-2.7	-1.9
Arm predicted mass (right)	2.3	11.8	39.8	3.9	2.2	1.7	4.7	2.8	-0.5	2.2	3.0	1.4	4.1	1.3	2.6	1.8	4.6	2.7	5.3	0.8	4.7	5.1	3.0	3.6	3.8	6.3	1.9
Age started oral contraceptive pill	2.3	2.9	11.8	2.3	1.3	0.5	1.3	-0.2	1.1	-0.3	1.8	-0.4	1.9	-1.6	0.8	0.6	0.3	1.1	2.4	1.7	1.3	2.5	2.7	3.4	2.0	0.8	2.5
Depression (Nagel 2018)	2.2	3.3	7.0	-2.4	-2.3	-1.9	-2.1	-1.8	-1.6	-2.0	-2.6	-1.8	-2.5	-1.7	-1.9	-1.9	-0.8	-0.7	-1.3	-1.3	-1.7	-1.5	-1.6	-1.9	-2.5	-1.4	-0.7
Ever highly irritable/argumentative for 2 days	2.2	2.7	8.2	-1.8	-2.5	-2.4	-0.4	-1.1	-0.8	-1.4	-1.9	-1.0	-1.6	-1.6	-2.7	-2.5	0.7	-0.5	0.3	-2.9	-0.0	0.2	-1.7	-1.5	-1.8	-0.3	-1.9
Medication: Gliclazide	2.2	2.4	7.1	0.8	2.2	2.5	0.1	1.4	1.5	2.3	1.4	1.8	0.7	1.3	2.0	2.7	1.9	1.5	-0.8	2.2	-1.1	0.3	1.5	0.4	1.1	0.3	1.7
Rheumatoid Arthritis	2.1	2.9	13.2	1.7	2.3	2.3	1.1	1.5	1.7	3.6	1.5	1.2	1.7	1.6	2.1	2.3	1.9	0.4	0.5	0.9	0.9	0.4	1.8	1.7	2.0	0.9	1.0
Medication for cholesterol	2.1	3.2	11.4	-1.9	-0.9	-0.3	-2.7	-1.1	-0.1	0.3	-1.7	-0.4	-2.4	-0.4	-1.1	-0.2	-1.7	-1.5	-3.1	-0.3	-2.7	-3.4	-1.5	-1.9	-1.9	-3.2	-1.0
Whole body water mass	2.1	11.8	42.1	3.7	2.3	2.0	4.7	3.1	-0.4	2.3	2.7	2.0	4.0	2.0	2.8	2.2	4.6	2.9	5.1	0.3	4.7	5.0	2.8	3.1	3.7	6.5	1.5
Breast Cancer	2.0	4.8	9.6	2.8	2.0	1.4	2.7	1.0	0.6	2.7	2.1	0.7	2.8	0.2	2.1	1.6	2.5	2.0	2.1	1.9	2.1	2.8	2.5	3.1	2.7	3.0	1.9
Average weekly fortified wine intake	2.0	2.3	8.0	1.7	0.5	-0.3	2.1	0.3	-0.0	1.2	1.2	-0.8	1.8	-0.5	0.7	-0.2	0.4	0.5	2.8	-0.0	2.8	2.7	1.5	2.1	1.6	2.3	1.4
Arm fat-free mass (right)	2.0	10.5	38.4	3.6	2.0	1.5	4.5	2.5	-0.8	2.0	2.7	1.1	3.8	1.2	2.3	1.6	4.3	2.5	5.1	0.6	4.5	5.0	2.7	3.3	3.5	6.2	1.8
Whole body fat-free mass	2.0	11.5	40.3	3.7	2.3	2.0	4.6	3.1	-0.5	2.2	2.7	2.0	3.9	1.9	2.7	2.1	4.6	3.0	5.1	0.3	4.6	4.9	2.7	3.1	3.6	6.4	1.5
Loneliness, isolation	2.0	2.8	8.0	-2.3	-1.5	-0.5	-2.2	-0.5	-1.0	-0.3	-2.2	-1.0	-2.5	-0.5	-1.1	-0.4	0.4	-0.9	-2.5	-1.2	-2.4	-2.8	-1.5	-2.5	-2.1	-1.6	-0.9
Arm predicted mass (left)	2.0	10.0	37.0	3.4	2.0	1.6	4.4	2.6	-0.8	1.7	2.5	1.4	3.7	1.4	2.3	1.8	4.6	2.4	4.7	0.2	4.6	4.7	2.6	3.1	3.4	6.1	1.7
Verbal and Numeric Reasoning (VNR)	1.9	4.5	15.1	-1.7	-1.8	-2.3	-2.8	-3.9	-1.4	-1.4	-1.7	-2.4	-2.1	-3.5	-1.8	-2.2	-3.1	-0.3	-1.2	0.3	-2.1	-0.5	-1.9	-0.1	-2.1	-3.6	-1.1
Leg predicted mass (left)	1.9	10.0	36.5	3.1	2.2	2.2	4.1	3.3	-0.3	2.9	2.2	2.3	3.4	2.6	2.8	2.4	4.8	2.9	4.4	0.0	4.0	4.2	2.3	2.2	3.2	6.0	0.9
Pain all over the body in last month	1.9	2.1	5.1	-1.9	-1.7	-1.3	-1.3	-0.8	-1.1	0.1	-1.7	-1.1	-1.5	0.1	-1.4	-1.2	-1.0	-1.6	-1.1	-1.4	-1.1	-1.7	-2.2	-2.3	-1.9	-0.7	-1.6
Alcohol intake versus 10 years previously	1.9	2.9	6.0	-2.3	-2.0	-1.4	-2.2	-1.4	-1.3	0.5	-1.8	-1.7	-2.5	-0.9	-1.6	-1.1	-0.1	-1.1	-1.5	-2.0	-2.0	-1.7	-1.9	-1.9	-2.3	-1.9	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	1.9	2.0	5.8	-1.6	-0.4	0.2	-1.5	-0.2	-1.8	-0.7	-1.2	0.5	-1.5	1.0	-1.1	-0.0	1.7	-1.5	-1.6	-1.2	-2.0	-2.2	-1.9	-2.4	-1.4	-1.1	-1.4
Frequency of depressed mood in last 2 weeks	1.8	2.5	5.4	-2.1	-1.9	-1.3	-1.9	-1.4	-0.9	-1.1	-2.3	-1.7	-2.3	-1.1	-1.1	-1.2	-0.7	0.4	-1.4	-1.1	-1.8	-1.4	-1.5	-2.2	-2.1	-1.4	-1.3
Ever used hormone-replacement therapy (HRT)	1.8	2.4	4.5	1.9	1.4	0.9	1.6	0.8	1.7	0.7	2.1	1.2	2.1	0.0	0.7	1.1	-0.3	2.1	1.3	1.4	1.4	1.8	2.1	2.0	1.9	1.4	2.1
Leg fat-free mass (left)	1.8	9.7	35.8	3.0	2.1	2.1	4.1	3.3	-0.4	2.8	2.2	2.2	3.4	2.6	2.7	2.3	4.7	2.9	4.4	-0.0	4.1	4.2	2.2	2.1	3.2	6.0	0.8
Arm fat-free mass (left)	1.8	9.0	36.4	3.2	2.0	1.6	4.1	2.5	-0.6	1.6	2.3	1.6	3.4	1.5	2.3	1.8	4.4	2.1	4.3	0.2	4.2	4.4	2.4	2.8	3.2	6.0	1.7
Hearing difficulty/problems: Yes	1.7	2.6	8.1	-1.4	-1.6	-1.9	-2.5	-2.9	-0.3	-1.5	-1.5	-0.8	-1.9	-2.6	-1.6	-1.7	-0.9	-0.9	-0.7	-0.9	-1.7	-1.3	-1.3	-0.3	-1.8	-2.4	-0.2
Medication: Metformin	1.7	2.5	6.5	1.3	1.9	2.0	1.7	1.4	-1.0	1.9	1.3	0.7	1.5	1.6	1.3	1.9	2.2	0.4	0.5	1.4	0.3	1.3	1.9	0.7	1.6	2.5	2.2
Financial difficulties in last 2 years	1.7	2.3	7.3	-2.1	-1.7	-0.8	-1.4	-0.3	-0.0	0.5	-2.3	-0.8	-2.0	0.3	-1.3	-0.8	-0.2	-0.4	-2.5	-1.2	-1.4	-1.8	-2.1	-2.7	-2.0	-0.8	-2.0
Trunk fat-free mass	1.7	9.9	35.9	3.5	2.0	1.4	4.3	2.4	-0.6	1.6	2.6	1.3	3.7	1.1	2.2	1.5	4.0	2.5	5.1	0.2	4.6	4.9	2.6	3.3	3.4	6.0	1.6
Pulse rate	1.7	2.8	7.3	1.5	2.0	2.4	1.6	2.7	-0.3	1.6	1.4	1.6	1.6	2.6	2.3	2.5	1.3	1.9	-0.1	0.8	-0.4	0.4	1.7	0.7	1.8	1.9	1.1
Trunk predicted mass	1.7	9.8	36.1	3.5	1.9	1.4	4.3	2.3	-0.6	1.6	2.6	1.3	3.7	1.1	2.2	1.6	4.0	2.5	5.1	0.1	4.5	4.9	2.5	3.3	3.4	6.0	1.6
Hearing aid user	1.7	1.9	8.0	1.8	0.8	0.0	0.7	-0.7	-0.8	-1.2	1.6	-1.0	1.7	-1.6	0.8	-0.2	-0.1	0.8	2.0	2.0	1.2	1.3	1.8	2.8	1.5	0.6	1.9
High cholesterol (Self-reported)	1.7	3.1	7.4	2.1	1.5	1.2	2.1	1.9	0.1	-0.0	1.8	0.9	2.1	0.7	1.9	0.9	2.0	0.2	2.6	0.7	2.5	2.1	2.0	1.9	2.1	2.7	1.8
Ever had prostate specific antigen (PSA) test	1.7	1.9	5.1	2.1	1.7	0.9	1.2	0.5	0.7	-0.8	1.9	0.7	1.7	-0.4	1.7	0.8	0.8	0.5	1.7	1.9	0.9	1.6	1.7	2.3	1.8	0.7	1.5
Current tobacco smoking	1.6	2.6	9.2	-1.6	-0.3	0.8	-0.8	1.6	-0.2	0.6	-1.4	1.3	-1.5	2.7	-0.1	0.7	-0.5	0.6	-3.0	-1.6	-1.5	-2.2	-1.9	-3.0	-1.1	-1.0	-2.6
Hearing difficulty/problems with background noise	1.6	2.5	6.2	-1.5	-1.8	-2.2	-1.9	-2.5	-0.0	-2.2	-1.4	-1.2	-1.7	-2.4	-1.8	-2.3	-0.8	-1.4	-0.1	-1.4	-1.0	-0.7	-1.6	-0.5	-1.7	-1.8	-0.8
Chronic bronchitis/emphysema (mother)	1.6	1.9	3.8	-1.9	-1.6	-1.1	-1.5	-0.5	-0.6	-1.6	-1.8	-0.8	-1.9	-0.5	-1.8	-1.3	0.4	-1.5	-1.1	-1.9	-0.6	-1.5	-1.6	-1.9	-1.8	-0.7	-0.6
Average weekly red wine intake	1.6	2.4	8.4	-1.2	-0.8	-1.0	-2.3	-2.8	-0.4	-0.4	-0.7	-1.4	-1.6	-2.1	-0.9	-0.9	-2.2	-2.6	-1.1	0.8	-2.9	-1.4	-0.8	-0.2	-1.4	-1.5	1.3
Basal metabolic rate	1.6	9.0	36.1	3.0	1.8	1.6	4.1	3.0	-0.7	2.0	2.1	1.9	3.3	2.0	2.3	1.8	4.6	2.3	4.5	-0.2	4.4	4.2	2.1	2.4	3.0	6.0	1.0
Waist Hip Ratio (WHR)	1.5	6.6	28.6	-1.7	-3.5	-3.4	0.1	0.0	-0.9	-2.1	-1.5	-0.1	-1.2	-0.9	-3.9	-4.1	1.9	1.4	1.0	-5.3	3.8	1.3	-3.3	-1.8	-2.2	0.3	-4.5
Fluid intelligence score	1.5	3.1	14.8	-0.8	-1.2	-2.0	-2.3	-3.8	-0.7	-0.7	-0.1	-2.7	-1.0	-3.4	-1.3	-1.7	-3.1	-1.0	-0.3	1.2	-1.3	-0.0	-1.0	1.0	-1.1	-2.6	0.1
Glaucoma (self-reported)	1.5	1.8	4.8	1.3	1.8	1.7	1.1	1.4	0.5	1.0	1.5	1.0	1.2	0.8	1.7	1.7	2.2	1.2	0.6	1.3	-0.8	1.1	1.8	1.4	1.4	1.1	1.4
Smoking status: Current	1.5	2.3	8.0	-1.4	-0.4	0.7	-0.7	1.4	-0.1	0.3	-1.4	1.4	-1.5	2.5	0.0	0.6	-0.7	0.8	-2.8	-1.5	-1.6	-2.0	-1.8	-2.8	-1.0	-1.0	-2.6
Allergy or Eczema	1.4	3.6	8.4	2.4	1.6	1.1	2.7	1.4	1.6	1.7	2.5	1.1	2.3	0.3	1.5	0.8	-0.1	1.8	2.9	0.9	2.7	2.3	1.9	2.4	2.2	2.2	1.1
Type 2 Diabetes (T2D) (2018)	1.4	2.7	8.5	1.2	1.4	1.8	1.7	2.9	-1.4	2.6	1.3	1.1	1.5	2.4	1.3	1.7	2.9	1.3	0.1	1.0	1.1	1.2	1.4	0.1	1.5	2.2	0.9
Ever had hysterectomy (womb removed)	1.4	1.6	6.4	1.3	0.3	-0.1	2.3	1.0	0.1	0.0	0.7	0.3	1.5	0.6	0.2	-0.3	1.9	2.0	2.0	-0.6	2.0	2.5	0.5	0.8	1.1	1.6	-0.4
Fed-up feelings	1.4	2.6	6.6	-2.2	-1.2	-0.3	-2.3	-0.7	0.9	1.1	-1.9	-0.1	-2.5	-0.4	-0.8	-0.1	-0.8	0.0	-2.3	-1.2	-2.6	-2.3	-1.4	-2.3	-2.0	-2.3	-1.3
Number of full brothers	1.4	1.8	12.8	-0.6	-0.5	-0.1	0.4	1.5	2.1	-0.7	-0.5	1.2	-0.4	2.2	0.3	-0.4	0.8	-0.6	-0.1	-2.1	0.7	-0.7	-2.0	-2.1	-0.5	-0.1	-3.6
Had major operations	1.4	1.6	5.5	-0.5	-1.8	-2.1	0.1	-1.4	-0.4	-0.8	-1.0	-1.2	-0.7	-1.7	-1.9	-2.1	0.6	0.5	1.2	-2.4	1.2	1.5	-1.2	0.1	-0.9	0.9	-0.6
Average weekly champagne plus white wine intake	1.4	2.0	4.1	1.9	1.2	0.9	2.0	1.5	1.1	0.6	2.0	1.7	1.8	0.4	1.8	0.8	0.7	1.3	2.0	0.6	1.5	1.7	0.8	1.7	1.8	0.3	-0.7
Medication: Lisinopril	1.4	1.8	4.0	1.7	1.1	0.9	2.0	0.9	-1.0	-0.7	0.9	0.3	1.6	0.5	1.5	1.1	-0.4	1.8	1.5	1.2	1.6	1.8	1.8	1.4	1.7	1.3	1.4
Unable to work because of sickness or disability	1.4	1.8	6.8	-1.3	-1.5	-0.8	0.3	1.0	-0.0	-1.3	-1.9	0.9	-1.2	1.5	-0.5	-0.9	0.8	-0.9	-0.2	-2.6	1.1	-0.1	-1.7	-2.6	-1.2	1.1	-2.1
Crohns Disease (2012)	1.3	2.0	4.7	2.2	1.7	1.3	1.6	1.3	1.4	0.5	1.9	0.3	2.1	0.6	1.5	1.2	0.8	0.6	1.3	1.2	1.6	1.2	1.7	2.1	2.0	1.0	0.9
Heel T-Score	1.3	10.2	18.6	4.2	3.9	3.7	3.3	4.2	2.2	3.4	3.8	-0.5	4.2	3.5	4.3	3.8	0.1	2.6	0.1	3.7	1.4	2.3	4.2	2.1	4.2	1.9	2.1
Hayfever, allergic rhinitis or eczema	1.3	2.7	6.4	2.1	1.3	0.9	2.5	0.9	1.5	1.2	2.2	0.8	2.0	0.2	1.4	0.7	-0.9	1.1	2.5	1.0	2.4	2.0	1.6	2.2	1.9	1.9	1.2
Alcohol usually taken with meals	1.3	2.0	7.8	-0.9	-0.2	-0.4	-2.0	-2.1	-0.4	0.2	-0.1	-1.0	-1.1	-1.3	-0.4	-0.2	-2.5	-2.6	-1.3	2.0	-2.8	-1.6	-0.7	0.0	-0.9	-1.9	0.6
Mouth/teeth dental problems	1.3	2.0	8.1	-1.5	-0.6	-0.3	-2.1	-1.4	-0.1	0.3	-1.0	-1.0	-1.6	-0.8	-0.6	-0.2	-2.4	-0.6	-2.3	1.0	-2.8	-2.0	-0.4	-1.1	-1.4	-2.4	-0.0
Hayfever/allergic rhinitis (self-reported)	1.3	1.7	6.2	1.6	0.7	0.1	1.6	-0.4	0.9	0.5	1.1	-0.5	1.3	-1.3	0.8	-0.1	-0.9	0.1	2.5	1.0	1.6	2.0	1.4	2.5	1.3	1.2	1.9
Health satisfaction	1.3	1.7	6.6	0.5	1.2	1.6	1.4	2.0	0.3	1.4	0.6	1.4	0.8	2.5	1.4	1.5	2.4	1.0	0.6	0.1	0.5	0.7	0.3	-0.5	0.8	2.6	0.1
Friendships satisfaction	1.3	1.6	3.7	1.3	1.3	1.1	1.1	0.7	1.4	1.9	1.6	0.7	1.4	0.4	1.5	1.1	1.6	0.3	1.5	1.3	0.2	1.4	1.0	1.4	1.3	1.8	1.1
Osteoporosis (self-reported)	1.3	1.6	8.0	-1.2	-0.1	0.2	-1.6	-0.7	0.3	0.6	-0.8	-0.5	-1.5	0.1	-0.7	0.0	-2.1	-0.4	-2.8	0.8	-2.1	-1.8	-1.1	-1.2	-1.2	-2.0	-0.4
Basal cell carcinoma (self-reported)	1.3	1.5	6.5	1.0	1.3	1.3	1.0	1.7	1.3	1.8	0.7	1.6	0.7	1.4	1.6	1.3	2.5	1.2	0.6	1.4	0.4	0.1	0.6	0.5	1.0	-0.0	-1.0
Reaction Time	1.2	2.3	11.2	-1.9	-1.6	-0.9	-0.5	0.2	-0.1	-1.2	-1.7	-0.3	-1.7	1.5	-1.3	-0.8	0.4	0.1	-0.9	-3.0	-0.2	-1.0	-2.3	-3.3	-1.7	0.5	-2.3
Smoking Status	1.2	2.8	10.0	-1.5	-0.7	0.5	-0.4	1.8	-0.4	1.3	-1.3	1.4	-1.3	2.8	-0.7	0.6	1.2	-1.2	-2.9	-1.7	-0.9	-2.5	-2.2	-3.2	-1.1	-0.4	-2.7
Medication: Co-codamol	1.2	1.3	5.1	0.6	-0.6	-1.1	1.2	-0.2	-1.7	-0.3	0.2	-1.2	0.7	0.1	-0.6	-1.0	2.0	0.4	2.3	-1.2	2.0	1.6	-0.3	0.6	0.4	1.9	-0.9
Past tobacco smoking	1.2	2.3	7.7	1.6	1.7	1.1	0.3	-0.2	1.4	-0.2	1.7	0.3	0.9	-1.1	1.9	0.9	-2.8	1.1	0.6	2.4	-0.3	0.9	2.5	2.4	1.4	-1.0	2.3
Depression (self-reported)	1.2	1.4	5.5	-1.4	-1.2	-1.1	-1.6	-1.4	0.8	-0.2	-1.1	-1.1	-1.4	-1.4	-1.1	-1.0	-1.3	-0.1	-0.9	-0.6	-1.6	-0.9	-0.8	-0.6	-1.4	-2.3	-0.9
Lung cancer (father)	1.2	1.4	5.1	-1.3	-1.4	-0.9	-1.1	0.1	0.3	-0.5	-1.2	0.6	-1.3	0.1	-0.6	-1.0	-0.7	-1.6	-1.0	-1.4	-0.2	-1.7	-1.4	-1.7	-1.3	-1.5	-2.3
Smoking status: Previous	1.2	1.8	8.3	-1.0	-1.7	-1.5	-0.0	-0.1	-1.6	-0.1	-1.1	-0.7	-0.5	0.0	-2.1	-1.2	2.9	-1.3	0.5	-2.1	1.2	-0.1	-1.9	-1.3	-1.0	1.1	-1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.4	5.6	2.2	1.3	0.9	2.2	1.8	0.9	0.2	2.3	1.4	2.1	1.3	1.8	0.7	1.7	-0.0	2.4	0.9	1.9	1.7	0.9	1.6	2.0	0.8	-1.2
Miserableness	1.2	2.1	5.7	-1.8	-1.2	-0.5	-2.1	-1.1	-1.1	1.2	-1.2	-2.2	-1.9	-0.6	-0.8	-0.0	-1.1	-0.8	-2.1	-0.2	-2.4	-2.2	-1.1	-1.5	-1.4	-2.2	-0.6
Ever smoked	1.2	2.2	6.5	-1.5	-1.4	-0.7	-0.4	0.5	-0.9	0.5	-1.8	0.1	-1.0	1.6	-1.5	-0.5	2.5	-0.8	-1.2	-2.3	-0.4	-1.3	-2.5	-2.6	-1.3	0.8	-2.4
Heart disease (siblings)	1.2	1.4	5.7	-1.5	-1.2	-0.9	-1.1	-0.4	0.6	-1.0	-1.8	-0.3	-1.4	-0.3	-1.0	-0.8	-1.1	-2.4	-1.0	-1.1	-1.0	-1.7	-1.2	-1.5	-1.3	-1.3	-0.8
Fasting Glucose	1.1	1.3	11.6	-0.8	-0.6	-0.5	-1.1	-1.4	-1.2	-2.3	-0.8	0.0	-0.9	-0.8	-0.8	-0.3	-0.4	-0.7	-0.8	0.4	-0.8	-1.8	-0.2	-0.4	-0.6	-3.4	-0.7
BMI	1.1	6.7	19.8	2.6	1.8	1.8	3.4	2.9	0.1	2.2	1.7	2.3	3.0	2.3	2.4	2.0	4.4	2.2	2.7	0.1	3.7	3.0	2.0	1.8	2.9	4.5	0.5
Respiratory disease	1.1	2.5	8.1	1.6	1.3	1.1	1.4	0.4	-0.1	2.3	1.6	-0.0	1.7	-0.2	1.0	1.2	0.6	0.9	1.9	1.6	1.4	1.9	2.4	2.0	1.6	2.6	2.8
Other serious medical condition/disability diagnosed by doctor	1.1	1.5	5.2	1.3	0.8	0.5	2.3	1.2	0.3	0.7	0.4	0.7	1.2	1.3	0.9	0.2	1.8	1.9	1.4	0.3	1.5	1.7	0.4	0.8	1.1	2.2	0.1
Hair/balding pattern: Pattern 2	1.1	1.4	3.9	1.9	0.9	0.2	1.6	0.8	0.6	-0.4	1.8	0.4	1.9	0.6	0.0	-0.1	0.7	-0.7	1.8	0.7	2.0	1.3	0.6	1.7	1.6	0.5	-1.4
Hair/balding pattern: Pattern 4	1.1	2.8	8.9	-2.2	-1.1	-0.8	-1.8	-2.0	-2.2	-0.8	-2.0	-2.6	-2.5	-1.6	-1.9	-0.7	-1.4	-0.1	-1.4	-0.5	-3.0	-1.3	-0.9	-1.2	-2.0	-1.2	0.7
Birth weight	1.1	2.4	11.3	1.1	-0.4	-1.4	1.0	-1.4	-1.8	-2.7	0.7	-1.1	1.2	-1.3	-0.8	-1.3	0.9	0.9	3.4	-0.7	2.7	2.7	-0.1	2.0	0.7	1.0	-1.3
Age at first live birth	1.1	1.9	8.9	1.6	1.8	1.4	-0.0	-0.3	0.3	2.3	2.2	-0.3	1.4	-0.3	1.7	1.4	-1.1	0.4	-0.0	3.0	-0.8	0.3	1.2	1.9	1.4	-1.4	0.6
Commuting to job workplace: Walk	1.1	1.2	4.7	1.4	1.0	0.8	0.7	0.8	0.5	1.2	1.5	0.7	1.3	-0.1	1.2	1.1	-0.4	2.2	0.5	1.2	0.7	0.9	1.2	2.0	1.4	0.1	0.3
Osteoarthritis (self-reported)	1.1	1.4	5.7	0.9	1.2	1.3	1.3	1.3	0.2	2.3	0.7	0.7	0.9	0.4	0.7	1.3	2.4	0.3	0.9	0.9	0.3	0.8	1.2	0.9	1.1	1.6	1.5
Angina	1.0	1.4	5.8	-1.2	-1.3	-1.0	-0.5	-0.1	-0.5	-0.4	-1.4	0.0	-1.4	0.3	-0.2	-1.2	1.4	-1.2	-0.2	-2.0	-0.3	-0.1	-2.4	-1.9	-1.3	-0.0	-1.9
Allergy	1.0	2.3	5.2	-1.8	-1.3	-1.2	-2.3	-1.5	-1.4	-0.9	-1.6	-1.1	-1.7	-0.6	-1.5	-1.0	0.3	-1.9	-2.1	-0.7	-2.2	-1.5	-1.7	-1.6	-1.8	-1.6	-1.1
Birth weight of first child	1.0	1.8	6.4	-0.0	-1.0	-1.7	0.2	-1.9	-1.7	-0.7	-0.9	-1.7	-0.1	-2.5	-1.8	-1.5	-0.2	1.4	1.5	-1.6	1.1	2.1	-0.1	1.7	-0.3	0.6	0.1
Angina (self-reported)	1.0	1.3	5.4	-1.1	-1.3	-1.0	-0.4	-0.1	-0.6	-0.0	-1.4	-0.2	-1.4	0.3	-0.2	-1.2	1.4	-0.9	-0.2	-2.0	-0.2	0.1	-2.3	-1.8	-1.3	0.2	-1.9
Number of full sisters	1.0	1.3	3.7	-0.9	-1.5	-1.6	-0.2	-1.4	-1.1	-1.4	-1.6	-0.0	-0.8	-1.9	-1.7	-1.7	0.9	-0.1	0.9	-1.6	0.2	0.5	-0.5	0.1	-1.1	0.7	0.4
Supplements: Vitamin C	1.0	1.2	3.2	1.4	0.8	0.7	1.7	1.1	0.2	0.5	1.1	1.3	1.7	1.1	1.1	0.7	0.7	0.3	1.8	0.7	0.8	1.4	0.4	0.7	1.5	1.5	-0.2
Medication: Paracetamol	1.0	1.6	5.0	1.4	0.9	0.9	2.2	2.0	1.3	-0.0	1.5	1.8	1.5	1.8	0.5	0.6	-0.5	0.8	1.2	-0.1	1.5	1.3	0.4	0.6	1.5	0.9	-1.6
Risk taking	1.0	1.4	7.2	-1.0	-0.6	0.2	-0.1	1.4	0.4	-0.9	-1.2	0.6	-0.9	1.8	-0.0	0.1	0.1	0.6	-1.5	-1.8	-0.7	-1.3	-1.7	-2.7	-0.9	-0.6	-2.2
Bipolar Disorder (2018)	0.9	1.5	3.9	0.6	1.4	1.7	0.0	1.3	1.8	-0.2	1.2	2.0	0.6	1.5	1.5	1.5	-0.2	-1.7	-0.6	1.9	-0.8	-1.8	1.0	-0.3	0.8	-0.3	0.6
Crohns Disease (2017)	0.9	1.9	3.9	1.8	1.8	1.6	1.1	1.8	2.0	0.5	1.8	0.7	1.8	1.6	1.7	1.6	1.3	0.7	0.2	0.7	1.1	0.6	1.6	1.3	1.7	0.7	0.4
Bipolar Disorder (2011)	0.9	0.9	3.5	0.9	1.1	1.0	0.3	0.9	1.9	-0.1	1.6	1.7	1.2	0.9	1.0	0.8	0.1	-0.1	-0.4	0.7	-0.2	-0.6	1.1	0.6	1.0	-0.6	0.4
LDL Cholesterol	0.9	1.4	5.8	-1.5	-1.3	-0.7	0.0	1.1	-0.3	0.9	-1.1	0.5	-1.0	1.1	-1.4	-0.6	0.2	0.6	-0.9	-2.4	0.1	-0.7	-1.8	-2.3	-1.2	0.3	-2.1
Hypothyroidism (self reported)	0.9	2.2	4.9	1.6	1.5	1.4	1.6	2.0	1.9	1.3	1.7	2.2	1.9	1.2	1.2	1.0	2.2	0.2	1.0	0.8	1.1	1.0	1.7	1.1	1.7	1.2	1.0
Diabetes (father)	0.9	1.1	4.0	-1.3	-1.8	-1.5	-1.0	-0.6	-2.0	-0.2	-1.3	-0.2	-1.2	-1.2	-1.6	-1.4	-0.5	-0.0	-0.2	-0.8	-0.2	-0.7	-1.0	-0.3	-1.2	-0.9	-0.8
Forced vital capacity (FVC)	0.9	3.5	16.4	2.0	0.4	-0.4	2.9	0.3	-1.3	0.1	1.4	0.4	2.2	0.8	0.4	-0.4	1.7	0.7	4.0	-0.2	3.8	3.5	0.0	1.6	1.7	3.0	-1.2
Weight	0.9	4.4	24.4	1.4	0.5	0.6	2.8	2.2	-1.1	1.2	0.8	1.3	1.9	1.5	0.8	0.8	4.0	1.0	2.9	-1.6	3.9	2.8	0.7	0.8	1.5	4.9	0.1
Forced vital capacity (FVC), Best measure	0.9	3.4	17.3	1.8	-0.0	-0.8	2.5	0.0	-1.6	-0.3	1.0	0.3	1.8	0.3	-0.1	-0.9	2.3	-0.2	4.2	-0.7	4.0	3.3	-0.2	1.5	1.3	3.0	-1.2
Pulse wave peak to peak time	0.9	1.1	4.3	1.0	1.2	1.3	1.2	0.8	0.5	0.3	0.7	0.7	0.9	0.7	1.1	1.5	0.4	0.6	0.7	1.2	0.9	0.3	1.4	0.5	1.2	1.6	2.1
Ever taken oral contraceptive pill	0.9	1.0	3.1	-1.1	-1.2	-1.0	-0.2	-0.8	-0.5	-1.2	-1.2	0.7	-1.0	-0.4	-1.1	-1.1	-0.0	0.8	-0.2	-1.6	-0.2	0.0	-1.4	-1.0	-1.1	-1.1	-1.8
Coronary Artery Disease (CAD)	0.8	1.0	2.2	-1.3	-1.4	-1.2	-1.2	-0.7	-0.8	-1.2	-0.7	-0.5	-1.3	-1.4	-1.1	-0.7	-0.6	-1.3	-0.9	-0.5	-0.7	-1.5	-0.6	-0.4	-1.0	-0.9	0.5
HDL Cholesterol	0.8	1.4	3.7	1.7	1.6	1.1	0.8	0.3	0.2	1.1	1.4	0.1	1.5	0.2	1.8	1.2	-0.6	1.1	0.8	1.4	0.2	1.4	1.9	1.7	1.5	0.1	1.0
Lung FVC	0.8	4.3	13.7	2.9	1.8	0.8	3.0	0.6	-0.6	0.1	2.5	1.2	3.0	1.3	2.2	1.2	1.2	1.4	3.7	2.0	2.5	2.8	1.5	2.5	3.0	1.9	-0.0
Number of treatments/medications taken	0.8	1.5	6.3	1.1	0.8	0.7	1.6	1.1	0.6	0.1	1.1	1.0	1.3	0.1	0.6	0.4	1.4	0.1	1.6	0.2	1.4	1.5	1.6	1.3	1.2	2.5	2.0
Average weekly spirits intake	0.8	1.0	5.1	-0.8	0.6	1.1	-1.0	-0.3	0.3	2.3	-0.6	0.2	-0.4	1.4	0.5	1.3	-0.3	-0.9	-2.2	0.6	-1.3	-1.3	-0.6	-1.2	-0.4	0.6	0.2
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	9.1	-0.5	-0.3	0.2	-0.7	0.2	-3.0	-1.1	-0.6	-0.9	-0.6	-0.6	-0.7	0.1	1.6	-0.1	-1.3	0.6	-0.5	-1.0	0.8	-0.1	-0.4	-0.8	0.7
Body mass index (BMI)	0.8	3.5	17.9	1.4	0.8	1.1	2.3	2.3	-0.7	1.7	1.0	1.3	1.8	1.6	1.5	1.4	3.6	0.2	2.0	-0.7	3.1	1.8	1.3	0.8	1.7	4.2	0.9
Waist circumference	0.8	3.0	16.2	0.5	-0.7	-0.6	1.9	1.5	-1.2	0.6	0.2	0.1	1.1	0.6	-0.7	-0.5	3.6	0.8	1.9	-2.6	4.0	2.3	-0.2	0.2	0.5	3.9	-0.8
Heart attack	0.8	1.0	3.1	-1.2	-0.2	0.3	-1.4	-0.0	0.9	0.0	-0.9	0.9	-1.5	0.4	0.0	0.2	1.3	-0.5	-1.5	-0.1	-1.8	-1.2	-1.5	-1.4	-1.2	-1.1	-1.0
Medication: Simvastatin	0.8	1.1	3.9	0.9	1.0	1.1	0.8	1.2	1.5	0.6	0.9	1.1	0.9	0.4	1.0	0.8	1.3	-0.1	1.1	0.3	0.7	1.2	1.2	0.9	1.0	2.0	1.6
Pulse wave reflection index	0.8	0.9	2.5	-0.9	-1.1	-1.3	-1.2	-1.4	1.2	-0.7	-0.3	-0.5	-0.7	-1.4	-1.2	-1.5	-0.3	-0.2	0.3	-1.1	-0.7	0.1	-0.6	-0.2	-1.0	-1.6	-1.2
Gout (self-reported)	0.8	1.1	3.3	-1.3	-1.4	-1.5	-0.2	-1.3	-0.1	-0.4	-1.6	-0.4	-1.0	-1.1	-1.8	-1.2	-1.7	-1.4	-0.3	-1.1	-0.0	-0.5	-0.9	-0.9	-1.3	0.4	0.3
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	5.5	1.2	1.2	1.2	1.5	1.8	1.8	0.5	1.1	2.3	1.4	1.3	1.1	0.8	2.0	0.2	0.8	-0.2	0.6	0.8	1.1	0.8	1.3	1.2	0.9
Medication: Amlodipine	0.8	1.1	4.6	1.1	0.5	-0.2	0.5	-0.9	-0.5	-0.1	0.9	-1.2	1.0	-1.4	0.7	0.1	0.1	1.8	1.6	0.5	0.2	1.6	1.6	2.2	1.0	0.3	1.3
Medication: Ventolin 100micrograms inhaler	0.8	1.0	4.1	0.8	0.8	1.1	1.0	1.5	0.3	0.4	1.1	1.7	0.9	0.9	0.6	0.8	2.0	1.2	0.7	-0.4	0.8	0.9	0.7	0.5	0.8	1.6	0.5
Leg fat percentage (right)	0.8	3.0	8.9	-2.3	-2.3	-1.6	-1.5	-0.7	-2.0	-0.7	-2.1	-1.0	-2.0	-0.7	-2.1	-1.5	0.6	-2.3	-1.4	-3.0	0.0	-1.5	-2.0	-2.2	-2.1	0.3	-1.1
Worry too long after embarrassment	0.8	1.4	4.7	-1.4	-1.0	-1.0	-1.5	-1.6	-0.1	-0.6	-1.7	-0.4	-1.8	-1.2	-0.5	-1.0	-0.2	-0.1	-1.2	-0.0	-2.2	-0.9	-1.2	-0.9	-1.6	-1.6	-0.4
Wheeze or whistling in the chest in last year	0.8	1.4	7.7	0.4	0.2	0.6	0.9	2.0	1.1	-1.2	0.7	2.2	0.4	1.2	0.3	0.2	2.8	1.4	0.9	-1.3	1.9	0.5	0.3	-0.4	0.5	1.0	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	3.6	-1.0	0.2	0.6	-1.3	-0.6	0.6	0.7	-0.4	1.1	-0.9	0.4	0.3	0.6	-1.6	-1.1	-1.5	0.2	-1.9	-1.4	-0.4	-1.1	-0.7	-1.3	0.5
Eye problems/disorders: Glaucoma	0.8	0.9	2.6	0.9	1.2	1.0	0.5	0.3	0.3	0.4	1.1	0.1	0.8	-0.2	1.1	1.1	1.6	0.1	0.7	1.2	-0.3	0.8	1.5	1.4	1.1	0.9	1.6
Irritable Bowel Disease (IBD)	0.7	1.7	3.3	1.6	1.3	1.2	1.5	1.7	1.6	0.4	1.2	1.6	1.8	1.8	1.3	1.2	1.8	0.7	0.5	-0.1	1.6	0.9	1.1	0.7	1.5	1.1	-0.1
Body Mass Index (BMI) (2010)	0.7	0.9	2.7	0.6	0.4	0.8	1.1	1.5	1.2	1.6	0.7	0.4	0.8	0.7	0.6	0.8	1.2	1.6	0.8	-0.0	1.6	1.0	0.1	0.2	0.6	1.4	-0.4
Triglycerides	0.7	1.2	5.6	-0.1	-1.0	-1.1	1.4	0.5	1.0	-0.5	-0.6	0.3	0.2	0.0	-1.1	-1.4	0.7	0.7	1.3	-2.4	2.3	0.7	-0.8	-0.4	-0.2	1.1	-1.9
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	3.9	-1.4	-0.2	0.7	-1.4	0.6	0.2	-0.2	-0.7	1.7	-1.4	0.9	0.3	0.7	1.1	-0.5	-1.7	-0.3	-1.9	-1.9	-0.7	-2.0	-1.1	-0.7	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	4.2	-0.1	0.3	0.9	0.6	1.4	-0.3	1.1	-0.1	1.6	0.2	2.0	0.1	0.9	1.6	-0.2	-1.0	-0.9	-0.1	-0.6	-0.4	-1.4	0.1	1.2	-0.8
Pulse wave Arterial Stiffness index	0.7	0.8	4.1	-0.8	-1.0	-1.1	-1.0	-0.7	-0.5	-0.2	-0.5	-0.5	-0.8	-0.6	-1.0	-1.3	-0.3	-0.3	-0.5	-1.0	-0.8	-0.1	-1.3	-0.4	-1.0	-1.4	-2.0
Loud music exposure frequency	0.7	0.8	3.8	0.2	0.8	0.9	-1.0	-0.5	0.7	-0.1	0.4	0.7	-0.0	-0.4	0.4	1.1	-0.1	-0.1	-1.2	1.7	-1.9	-1.1	0.9	0.5	0.3	-1.4	1.0
Blood clot in the leg (DVT)	0.7	0.9	3.5	-0.6	0.3	1.0	-0.1	1.6	0.9	0.6	-0.5	1.9	-0.4	1.9	0.5	1.0	1.2	0.8	-0.8	-0.8	-0.6	-1.1	-0.5	-1.7	-0.2	0.2	-0.7
Headache pain in last month	0.7	1.2	4.5	1.0	1.4	1.6	0.5	1.1	1.0	0.6	1.3	2.1	0.8	0.8	1.2	1.4	1.0	2.0	0.1	0.5	-0.1	0.4	1.3	0.7	1.1	0.3	1.0
Qualifications: College or University degree	0.7	2.2	13.5	0.5	1.3	0.8	-1.4	-1.7	1.5	1.4	0.9	0.2	-0.0	-1.3	1.3	1.0	-2.3	-1.2	-0.9	3.7	-2.3	-0.8	0.9	1.5	0.4	-1.9	1.6
Pulse rate, automated reading	0.7	2.3	6.2	1.3	1.8	2.3	1.4	2.5	-0.8	0.7	0.7	1.9	0.9	2.1	2.3	2.1	1.7	2.1	-0.4	0.8	0.5	0.6	1.6	0.7	1.5	1.1	0.7
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.7	-1.2	-0.9	-0.6	-1.0	-0.4	-0.2	-0.6	-1.0	0.5	-1.3	-0.3	-0.8	-0.9	0.7	-1.7	-0.7	-1.2	-0.6	-1.1	-0.7	-1.6	-1.2	-0.2	0.1
Knee pain experienced in last month	0.7	1.1	4.9	1.1	0.9	0.8	1.6	1.5	1.1	0.9	0.6	1.0	1.0	1.4	0.9	0.7	0.5	2.2	1.1	0.4	0.5	1.0	0.4	0.1	1.1	1.3	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	8.8	0.5	-0.5	-0.8	2.0	0.9	-0.4	0.1	0.6	0.8	0.9	0.6	-0.7	-1.1	-0.0	-0.1	2.1	-1.6	3.0	1.8	-0.9	0.1	0.4	1.7	-1.9
Diabetes diagnosed by doctor	0.7	1.2	6.3	0.4	0.9	1.1	0.5	1.0	-1.8	1.9	0.7	-0.4	0.7	1.0	0.2	1.1	2.5	0.1	-0.5	0.9	-0.2	0.5	1.2	-0.1	0.7	1.6	1.6
Qualifications: nursing, teaching	0.7	1.1	3.4	1.0	0.3	-0.2	0.5	-0.7	0.4	1.1	1.4	-0.7	1.0	-1.1	0.5	-0.0	-1.0	0.5	1.5	1.8	-0.1	1.8	0.7	1.8	0.8	0.6	1.7
Eye problems/disorders: Cataract	0.7	0.8	3.3	-1.0	-0.4	-0.3	-0.5	0.3	-1.0	-1.8	-0.7	0.5	-1.1	0.2	-0.6	-0.9	-1.2	-1.0	-1.0	-0.0	-0.4	-1.3	-0.7	-0.9	-0.9	-1.3	-1.0
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	7.5	0.6	-0.6	-1.1	1.2	-0.4	0.2	-1.1	0.2	0.4	0.7	-0.5	0.0	-1.1	0.5	-0.1	2.7	-1.5	1.9	1.5	-1.0	0.7	0.4	1.2	-0.9
Asthma (self-reported)	0.7	1.4	4.2	1.4	1.0	0.9	1.0	0.5	-0.4	0.8	1.3	-0.2	1.2	-0.3	0.7	0.8	0.1	1.5	1.3	1.5	1.5	1.4	2.0	1.4	1.3	1.2	1.9
Pain type(s) experienced in last month: Hip pain	0.7	0.9	6.1	0.1	0.2	0.8	0.5	1.6	0.2	0.7	-0.1	1.2	-0.0	1.5	1.1	0.7	2.5	0.3	-0.0	-1.3	0.2	-0.1	-0.1	-1.0	0.1	1.1	-0.9
Alcohol drinker status: Never	0.7	0.9	4.2	0.7	1.5	1.5	0.1	0.4	0.8	0.5	0.7	0.5	0.3	0.1	1.1	1.5	-0.6	0.3	-0.9	2.0	-0.6	-0.3	1.3	0.9	0.8	-0.6	1.1
Depressed Affect (Nagel 2018)	0.6	1.2	4.2	-1.2	-0.7	-0.0	-1.5	-0.0	0.3	0.8	-0.9	-0.3	-1.6	0.1	-0.1	0.2	-0.0	-0.6	-1.4	-0.6	-2.1	-1.8	-1.1	-1.6	-1.1	-2.0	-1.4
Ulcerative Colitis (UC)	0.6	1.2	4.4	0.9	0.4	0.5	1.6	1.6	0.7	0.1	0.2	2.1	1.2	1.8	0.6	0.6	1.9	0.7	0.6	-0.8	1.6	1.0	0.1	-0.1	0.9	1.2	-0.8
Major Depression (MDD)	0.6	0.7	3.1	0.3	-0.7	-0.9	1.1	0.8	-0.6	-1.0	0.1	0.4	0.4	0.3	-0.9	-1.1	0.8	0.3	1.1	-1.8	1.6	0.9	-0.4	-0.0	0.1	1.2	-0.9
Mean Putamen Volume	0.6	0.7	5.2	-0.1	-1.1	-1.0	0.4	0.3	-2.3	-0.8	-0.4	-1.6	0.0	0.1	-0.9	-0.9	0.4	-0.2	0.5	-0.7	0.7	0.4	-0.9	-0.5	-0.1	0.6	-1.0
HbA1C	0.6	0.7	3.7	-0.4	-1.2	-1.1	-0.1	-0.1	-0.6	0.1	-0.8	-0.7	0.0	-0.3	-1.3	-1.1	0.2	-0.8	0.4	-1.9	1.3	-0.4	-0.4	-0.7	-0.6	1.0	-0.6
Chronotype (morning person)	0.6	1.5	6.7	-0.4	-0.8	-0.5	0.8	1.2	1.6	-0.7	-0.5	1.3	-0.0	1.1	-0.7	-0.7	1.9	-0.7	0.5	-2.6	2.0	0.1	-1.5	-1.4	-0.4	1.2	-2.1
Trunk fat percentage	0.6	2.5	11.9	-2.0	-2.1	-1.5	-0.8	0.0	-1.5	-0.7	-2.0	-0.1	-1.5	0.1	-1.8	-1.4	1.3	-1.3	-0.6	-3.5	1.0	-0.8	-2.2	-2.2	-1.8	0.7	-1.8
Hand grip strength (right)	0.6	1.7	5.8	-1.2	-1.5	-1.5	-0.8	-1.8	-2.4	-2.1	-1.5	-1.2	-1.2	-1.6	-2.1	-1.6	-0.1	-0.3	0.0	-1.1	-0.2	-0.1	-1.3	-0.6	-1.4	-0.7	-0.3
Medication: Atenolol	0.6	0.7	2.8	-0.2	-1.1	-1.4	0.3	-0.8	-0.1	0.5	-0.5	-0.5	-0.4	-1.5	-0.8	-1.4	0.7	-0.7	1.7	-0.9	1.0	0.8	-0.8	0.4	-0.4	0.4	-0.2
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	2.2	-0.8	-1.0	-0.8	-0.2	-0.2	-0.2	-0.7	-0.6	1.2	-0.6	-0.3	-0.9	-1.1	0.4	0.4	0.2	-1.3	-0.8	-0.5	-1.1	-0.8	-0.9	-1.2	-1.5
Worrier / anxious feelings	0.6	1.1	3.9	-0.9	-0.8	-0.8	-1.6	-1.6	-0.9	-0.2	-0.7	-0.8	-1.1	-2.0	-0.9	-0.7	0.7	-0.8	-0.6	0.8	-1.6	-1.2	-0.1	0.2	-1.0	-1.6	1.0
Forced expiratory volume in 1-second (FEV1)	0.6	2.1	8.6	1.6	0.5	0.1	2.3	0.9	-0.7	0.4	1.2	0.8	1.8	1.2	0.7	0.1	1.8	0.2	2.9	-0.1	2.7	2.3	-0.2	0.9	1.4	2.3	-1.3
Noisy workplace	0.6	0.7	4.1	-0.9	-0.4	0.1	-1.1	0.2	-1.4	-0.2	-1.0	0.8	-0.9	0.3	0.5	0.2	2.0	-1.0	-0.7	-0.6	-0.6	-1.5	-0.0	-1.1	-0.8	0.3	0.5
Mouth/teeth dental problems: Dentures	0.6	1.0	3.7	0.6	0.1	0.2	1.5	1.0	0.7	0.9	-0.0	1.1	0.8	1.2	-0.0	0.1	1.6	0.8	1.0	-1.4	1.8	1.5	-0.3	-0.1	0.6	1.9	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	7.9	1.3	0.1	-0.3	1.8	0.4	-1.3	-0.0	0.7	0.3	1.3	0.6	0.1	-0.4	2.3	-0.3	2.8	-0.6	2.7	2.1	-0.3	0.9	1.0	2.0	-1.2
Medication: Paracetamol	0.6	0.9	3.5	0.9	0.6	0.7	1.9	1.6	0.7	0.1	0.9	1.5	1.1	1.5	0.2	0.5	-0.1	0.6	0.8	-0.2	1.3	1.0	0.3	0.4	1.1	1.2	-0.9
High blood pressure (siblings)	0.6	0.9	4.5	1.1	-0.1	-0.3	1.6	0.9	-0.3	-0.2	0.3	0.1	0.9	-0.3	0.9	-0.7	0.4	0.4	2.1	-0.3	1.6	1.9	0.7	1.1	0.8	0.8	-0.4
Number of children fathered	0.6	0.6	2.7	-0.5	-1.0	-1.0	0.1	-0.2	-0.7	-1.7	-0.9	0.2	-0.6	-0.0	-0.3	-1.1	-0.7	-0.5	0.5	-1.5	0.3	-0.1	-0.8	-1.0	-0.6	-0.1	-1.1
Medication: Ibuprofen	0.6	0.7	2.6	0.1	0.7	1.1	0.4	1.5	0.4	0.9	0.5	1.6	0.5	1.6	0.2	1.1	1.2	0.0	-0.9	-0.3	-0.2	-0.6	0.3	-0.7	0.4	0.8	-0.2
Overall health rating	0.6	1.3	6.1	-0.4	-0.1	0.6	1.0	2.0	-0.1	0.7	-0.8	1.8	-0.4	2.0	0.4	0.4	2.5	-0.1	-0.3	-1.6	0.3	-0.2	-0.8	-1.7	-0.3	1.6	-1.2
Age at last live birth	0.6	0.8	3.2	0.8	1.3	1.4	0.1	0.3	-0.4	1.8	0.7	0.4	0.6	0.5	1.2	1.6	0.3	0.5	-0.2	1.6	-1.1	0.0	0.6	0.8	0.8	-0.1	0.6
Family relationship satisfaction	0.6	0.7	1.6	-0.8	-1.3	-1.2	-0.5	-1.1	0.4	0.2	-1.0	-0.5	-0.6	-0.9	-1.1	-1.0	0.8	-1.2	0.5	-1.2	-0.1	0.4	-0.9	-0.6	-0.9	1.0	0.2
Leg pain on walking	0.6	0.8	1.8	1.1	0.9	0.6	1.1	1.0	0.0	0.8	1.2	0.4	1.0	0.3	0.9	0.4	1.2	0.2	1.2	0.4	0.7	1.0	1.3	1.1	1.0	1.1	0.5
Mood swings	0.6	1.1	5.3	-1.4	-0.9	-0.1	-0.8	0.6	0.9	0.7	-1.0	0.5	-1.4	1.0	-0.3	0.1	0.5	0.2	-1.1	-1.2	-0.9	-1.3	-1.2	-2.3	-1.0	-0.7	-1.7
Long-standing illness, disability or infirmity	0.6	0.9	4.3	0.9	0.4	0.3	1.4	0.8	0.2	0.3	0.3	0.5	0.9	0.3	0.5	0.1	2.1	1.5	1.5	-0.0	1.1	1.7	0.7	0.8	0.8	1.5	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	5.1	0.0	0.2	0.4	0.8	1.4	1.3	-0.7	-0.1	2.3	0.2	1.4	0.4	0.4	1.0	0.3	0.2	-1.0	0.1	-0.2	-0.1	-0.8	0.2	0.4	-1.0
Back pain experienced in last month	0.6	0.8	3.7	-0.5	-0.8	-0.6	0.4	0.3	-1.8	-0.0	-1.3	0.8	-0.8	0.6	-0.9	-0.7	1.6	0.2	0.1	-1.9	0.8	0.2	-1.2	-0.9	-0.5	0.3	-1.1
Mother’s age at death	0.6	0.7	2.9	0.5	-0.3	-0.9	0.7	-1.1	-0.8	-1.7	0.5	-0.9	0.9	-1.1	-0.5	-0.9	-0.6	-0.6	1.3	-0.2	0.6	1.3	-0.0	1.2	0.5	0.8	0.6
Tinnitus: Yes, now most or all of the time	0.6	0.7	5.6	0.7	0.6	0.5	0.9	0.6	0.8	0.1	0.7	2.4	0.8	0.3	0.2	0.5	0.6	0.3	0.5	-0.1	-0.1	0.2	1.0	0.5	0.6	1.3	1.4
Irritability	0.6	1.1	4.0	-0.8	-1.4	-1.5	-0.1	-0.4	0.1	-1.1	-1.2	-1.0	-0.8	-0.5	-1.0	-1.5	0.0	-0.6	-0.2	-2.0	0.8	0.3	-1.0	-1.1	-0.9	-0.5	-1.9
Supplements: Calcium	0.6	0.7	2.7	1.0	0.7	0.4	0.6	-0.1	-0.6	0.8	0.5	-0.7	0.8	-0.2	0.5	0.5	-0.9	1.6	0.3	1.2	0.0	1.0	1.3	1.1	0.8	0.7	1.1
Heart attack/myocardial infarction (self-reported)	0.6	0.7	1.9	-0.9	-0.2	0.2	-1.1	0.0	1.2	0.0	-0.6	0.9	-1.1	0.3	0.0	0.1	1.3	-0.6	-1.1	-0.2	-1.3	-0.8	-1.4	-1.1	-0.9	-0.8	-1.0
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	3.1	-0.5	0.3	1.0	0.0	1.5	0.9	0.4	-0.3	1.8	-0.3	1.7	0.5	0.9	1.0	0.7	-0.8	-0.6	-0.5	-1.1	-0.5	-1.5	-0.2	0.2	-0.6
Alcohol drinker status: Previous	0.6	0.7	2.5	0.5	0.5	0.7	1.0	1.6	1.3	1.5	0.9	0.5	0.6	1.2	0.8	0.6	-0.1	0.7	-0.0	0.1	0.9	0.8	0.1	-0.2	0.6	1.2	-0.5
Bipolar Disorder or Schizophrenia	0.5	1.3	4.1	-0.2	0.5	1.3	-0.6	2.0	1.3	0.8	0.7	1.8	-0.1	2.0	1.2	1.2	0.3	-0.1	-1.4	0.2	-1.5	-2.0	-0.0	-1.7	-0.0	-0.6	-0.1
Primary Biliary Cirrhosis	0.5	0.7	6.1	0.1	0.1	0.1	0.6	0.7	2.5	0.6	-0.4	1.4	-0.1	0.6	0.5	0.2	-0.7	1.4	-0.0	-0.9	-0.2	0.4	-0.8	-0.2	0.1	-0.5	-1.5
Ulcerative Colitis	0.5	0.7	1.9	0.8	0.1	-0.0	1.3	1.0	0.2	-0.4	0.2	0.8	0.9	1.1	0.2	0.0	1.3	1.2	1.0	-0.8	1.4	1.1	0.0	-0.1	0.6	0.7	-1.2
Relative age of first facial hair	0.5	1.1	4.5	-0.6	-1.4	-1.1	0.5	0.9	0.3	0.3	-0.9	1.0	-0.5	0.6	-0.8	-1.2	-0.2	-0.2	0.9	-2.1	1.3	0.8	-1.3	-1.5	-0.7	1.2	-1.7
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	2.7	-0.5	0.2	0.4	-0.4	-0.6	-0.4	1.2	-0.4	-1.6	-0.4	-0.2	-0.3	0.3	-0.3	-0.5	-0.9	0.7	-1.3	-0.3	0.4	-0.6	-0.4	0.7	1.2
Townsend deprivation index at recruitment	0.5	0.7	2.9	-0.2	0.3	0.8	0.0	1.2	1.6	0.9	-0.3	0.6	-0.2	1.7	0.6	0.8	1.1	0.6	-1.0	-0.7	0.8	-0.5	-0.7	-1.0	-0.0	0.1	-1.1
Qualifications: CSEs or equivalent	0.5	0.7	4.8	-1.0	-1.0	-0.7	-0.4	-0.7	-2.2	-0.3	-1.1	-0.4	-0.9	-0.2	-1.5	-0.6	-0.3	0.6	-0.4	-0.8	-0.2	-0.7	-0.8	-1.0	-0.8	-0.0	-0.5
Supplements: Glucosamine	0.5	0.7	3.2	0.6	0.7	0.5	0.6	0.3	0.0	1.8	1.0	0.2	0.8	0.2	-0.1	0.7	0.8	0.2	0.6	1.6	0.6	0.5	0.7	0.8	0.8	1.4	1.1
Medication: Levothyroxine sodium	0.5	0.9	5.1	0.4	0.9	1.2	0.7	1.5	0.8	0.7	0.5	1.9	0.4	1.4	0.8	0.8	2.2	-0.5	-0.2	-0.3	-0.5	-0.1	0.4	-0.1	0.5	0.9	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.7	3.6	-1.0	-0.3	0.2	-1.1	-0.1	-0.6	0.4	-0.7	0.3	-1.1	0.4	-0.2	0.4	1.5	-0.2	-1.4	0.0	-1.9	-1.0	-0.4	-1.4	-0.8	-0.7	-0.2
Father’s age at death	0.5	0.7	3.3	-0.8	-0.4	-0.2	-0.9	-1.4	-1.8	0.6	-0.8	-1.1	-0.6	-1.0	-0.5	0.2	-0.5	-0.5	-0.8	0.6	-1.1	-0.8	-0.0	-0.1	-0.5	-0.2	1.3
Qualifications: A levels/AS levels or equivalent	0.5	1.1	3.9	-0.7	-0.4	-0.5	-1.6	-1.9	-0.2	0.1	-0.7	-0.8	-0.7	-1.6	-0.5	-0.4	-2.0	-0.6	-1.0	1.1	-1.6	-0.9	-0.7	0.5	-0.7	-1.8	0.3
Asthma	0.5	0.9	2.9	1.0	0.9	1.0	0.5	0.4	-0.5	1.0	1.1	-0.3	0.9	-0.2	0.7	0.8	-0.0	1.3	0.8	1.4	1.0	0.8	1.7	1.1	1.0	0.9	1.7
Prospective memory result	0.5	0.7	2.4	0.3	-0.7	-1.0	0.4	0.2	-0.6	-1.2	0.1	0.0	0.3	-0.2	-0.6	-0.8	0.7	0.1	1.5	-1.5	1.4	1.1	-0.5	0.4	0.1	0.2	-1.5
Arm fat mass (right)	0.5	2.1	12.5	0.4	-0.2	0.2	1.6	1.7	-0.9	0.9	-0.1	1.1	0.9	1.2	0.4	0.4	3.2	0.2	1.6	-2.2	2.8	1.5	0.1	-0.2	0.6	3.5	-0.2
Breastfed as a baby	0.5	0.7	4.1	-0.1	0.8	0.8	-1.1	-0.7	0.0	0.7	-0.4	0.1	-0.6	0.2	0.6	1.0	0.0	0.0	-1.4	1.2	-2.0	-0.8	0.6	-0.3	-0.2	-1.3	0.5
Body fat percentage	0.5	2.1	10.6	-1.9	-1.9	-1.2	-0.6	0.3	-1.5	-0.5	-1.9	0.1	-1.4	0.2	-1.6	-1.1	1.3	-1.2	-0.8	-3.3	1.0	-1.0	-1.9	-2.2	-1.6	0.9	-1.4
Comparative body size at age 10	0.5	1.3	4.1	1.1	1.1	0.6	0.1	-0.5	0.7	0.3	2.0	0.0	1.2	-1.0	1.3	0.8	0.2	-0.1	1.4	1.8	0.3	1.3	1.7	1.9	1.0	0.8	2.0
Mouth/teeth dental problems: Loose teeth	0.5	0.6	5.9	-0.2	-0.3	-0.5	0.2	-0.9	-1.0	-1.2	-0.4	-0.2	-0.1	-0.8	-0.9	-0.3	2.4	-1.1	0.3	-0.5	0.4	0.2	-0.4	0.5	-0.1	1.2	0.6
Medication for pain relief, constipation, heartburn	0.5	0.8	4.9	-0.0	-0.5	-1.0	-1.0	-1.6	-0.1	-0.4	0.1	-2.0	-0.1	-1.6	-0.1	-0.7	-2.2	0.1	-0.0	0.7	-0.5	0.0	0.0	0.8	-0.3	-1.1	0.6
Neck or shoulder pain in last month	0.5	0.7	2.0	0.4	-0.4	-0.4	0.9	1.2	-0.2	0.6	-0.3	0.5	0.3	0.6	-0.0	-0.4	1.3	1.3	1.2	-1.4	1.4	1.3	-0.1	-0.0	0.3	0.7	-1.2
Medication: Omeprazole	0.5	0.6	3.0	-0.3	-1.0	-0.9	-0.2	0.0	-0.7	-1.1	-0.5	-1.7	-0.3	-0.7	-1.0	-1.1	-0.6	0.0	0.2	-1.6	1.4	0.0	-0.3	-0.2	-0.5	-0.4	-0.5
Medication: Seretide 50 evohaler	0.5	0.5	1.8	0.3	1.0	1.3	0.4	0.8	0.2	0.6	-0.0	1.1	0.3	1.1	0.5	1.2	1.3	0.1	-0.3	0.4	0.6	-0.2	0.7	0.0	0.4	1.0	0.8
Suffer from ‘nerves’	0.5	0.8	4.1	-0.8	-1.0	-0.9	-1.1	-0.7	-2.0	1.1	-0.4	-1.7	-0.9	-0.7	-0.6	-0.8	-0.1	-0.8	-0.2	0.1	-1.2	-0.3	-0.8	-0.5	-0.9	-0.3	0.1
Illnesses of siblings: Diabetes	0.5	0.6	2.7	-0.1	-0.6	-0.8	-0.4	-1.0	-1.5	-1.5	-0.4	0.0	0.0	-1.4	-0.6	-0.9	-0.2	-1.6	0.4	-0.6	0.5	0.7	-0.1	0.2	-0.3	-0.0	0.8
Ever had bowel cancer screening	0.5	0.6	3.5	0.6	-0.0	-0.4	0.9	0.1	0.1	-1.1	0.4	-0.1	0.4	-0.9	-0.2	-0.4	0.2	1.7	1.2	-0.0	0.8	1.9	0.6	1.1	0.4	0.2	-0.3
Illnesses of father: None of the above (group 1)	0.5	0.6	3.9	-0.5	0.6	1.0	-0.8	0.4	0.6	0.2	-0.1	0.3	-0.5	1.3	-0.2	0.8	1.1	-0.3	-2.0	0.0	-0.6	-1.5	-0.2	-1.2	-0.5	-0.4	-0.1
Arm fat mass (left)	0.5	2.1	12.1	0.3	-0.4	-0.1	1.5	1.4	-1.2	0.7	-0.1	0.9	0.8	0.9	0.2	0.1	3.2	0.1	1.7	-2.1	2.8	1.6	0.0	0.0	0.5	3.5	-0.1
Number of self-reported non-cancer illnesses	0.5	0.9	3.0	0.0	-0.9	-1.1	0.7	-0.3	-0.5	0.0	-0.3	-1.2	0.1	-1.7	-0.7	-1.1	1.1	-0.4	1.7	-0.4	1.5	1.4	0.6	1.0	-0.1	1.4	1.2
Medication: Blood pressure	0.5	0.9	2.7	0.6	-0.3	-1.0	0.5	-1.2	-1.1	-0.9	-0.0	-0.8	0.7	-1.3	-0.5	-0.9	0.9	-0.6	1.6	0.0	1.4	1.6	0.3	1.4	0.3	1.4	0.8
Schizophrenia (2018)	0.4	0.9	3.7	-0.8	-0.5	0.3	-0.8	1.4	0.2	1.2	-0.1	0.7	-0.7	1.4	0.4	0.4	0.6	-0.1	-1.4	-1.4	-1.3	-1.3	-0.8	-1.9	-0.6	-0.5	-0.7
Ovarian Cancer	0.4	0.5	3.3	0.4	0.9	0.9	0.6	1.1	-0.9	0.2	0.5	0.4	0.4	1.2	0.6	0.7	1.8	-0.1	-0.2	1.0	0.4	-0.3	0.3	-0.2	0.5	0.6	0.2
Lupus	0.4	0.6	1.7	0.6	1.0	1.2	0.3	1.1	0.9	0.5	0.8	1.3	0.5	1.2	1.2	1.2	0.1	0.8	-0.4	1.0	-0.1	0.1	0.6	0.1	0.7	-0.1	-0.3
Schizophrenia (2014)	0.4	0.9	3.1	-0.8	-0.0	0.8	-1.1	1.4	-0.1	1.2	-0.0	1.0	-0.6	1.6	0.7	0.8	0.5	-0.6	-1.6	-0.5	-1.3	-1.8	-0.5	-1.8	-0.5	-0.4	0.0
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.9	-0.2	-0.6	-0.7	-1.3	-0.9	-0.8	-0.8	0.1	-1.4	-0.2	-0.7	-1.0	-1.0	-0.2	-0.4	-0.4	-0.6	0.2	-0.4	-0.9	0.0	-0.6	-0.5	-0.9
Blood Platelet Count	0.4	4.5	15.6	-2.6	-0.7	0.1	-3.5	-1.3	-1.9	-0.7	-1.9	-0.6	-2.7	-0.3	-1.0	0.1	0.7	-1.9	-3.8	-0.1	-4.0	-3.7	-1.1	-2.3	-2.2	-3.3	-0.4
Height	0.4	8.0	34.9	1.4	-1.4	-2.3	3.1	0.3	-1.3	-2.2	0.7	-0.3	1.8	-1.1	-1.6	-2.8	1.4	2.9	5.9	-4.0	5.7	5.7	-0.8	2.0	0.8	4.1	-2.2
Systolic Blood Pressure	0.4	1.8	10.0	-1.0	-1.7	-2.1	-0.7	-1.9	-0.7	-1.3	-1.7	-1.4	-1.1	-1.8	-0.9	-2.0	-3.2	-1.4	0.2	-0.3	-0.0	0.5	-1.1	-0.0	-1.1	-0.6	0.3
Systolic blood pressure, automated reading	0.4	1.2	4.7	0.9	-0.2	-0.6	1.6	0.2	-0.6	-0.5	-0.0	-1.0	1.0	-0.3	0.6	-0.6	-2.0	-0.2	1.8	0.6	1.8	2.2	0.7	1.1	0.9	1.8	0.8
Supplements: Zinc	0.4	0.4	1.7	0.6	-0.2	-0.5	0.8	-0.2	-0.7	-0.0	0.7	-0.4	0.8	-0.5	-0.4	-0.8	-0.6	0.9	1.2	0.3	0.6	1.3	-0.1	0.8	0.4	0.4	-0.4
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.8	0.7	0.5	0.4	0.9	0.6	0.1	0.4	0.6	0.8	1.0	0.6	0.2	0.5	0.9	0.3	0.5	-0.1	0.8	0.8	0.5	0.4	0.8	1.4	0.8
Serious illness, injury or assault to yourself	0.4	0.5	1.7	0.2	0.2	0.4	0.9	1.2	-0.2	0.2	-0.0	1.0	0.3	1.2	0.9	0.1	0.9	0.6	0.6	-1.3	0.4	0.8	-0.1	-0.4	0.2	1.3	-0.2
Multivitamins +/- minerals	0.4	0.5	2.3	-0.5	-0.2	0.0	-0.5	0.0	0.1	1.0	-0.4	-0.6	-0.2	0.7	-0.7	0.2	1.5	-1.2	-0.8	0.1	0.4	-0.9	-0.9	-1.1	-0.4	1.0	0.2
Trunk fat mass	0.4	1.7	9.1	-0.9	-1.4	-0.9	0.5	0.7	-1.7	-0.1	-1.2	0.3	-0.4	0.4	-1.0	-0.8	2.3	-0.4	0.8	-3.0	2.1	0.6	-1.2	-1.1	-0.7	2.3	-1.1
Nervous feelings	0.4	0.8	3.1	0.6	0.7	0.5	0.8	0.3	-0.4	1.3	0.2	-0.3	0.7	0.2	0.7	0.7	1.6	0.5	0.7	1.5	0.0	0.9	1.2	1.0	0.8	1.3	1.8
Diabetes (self-reported)	0.4	0.7	4.2	-0.2	0.2	0.4	0.0	0.2	-2.1	1.2	-0.1	-0.8	-0.0	0.2	-0.3	0.4	2.1	-0.0	-0.5	0.0	-0.5	0.4	0.6	-0.4	-0.0	1.4	1.4
Hip circumference	0.4	1.7	12.1	1.0	0.4	0.3	1.6	1.0	-0.7	1.4	0.6	0.2	1.4	0.6	0.3	0.7	2.2	-0.1	1.3	-0.8	2.4	1.5	0.7	0.9	1.1	3.5	0.9
Number of live births	0.4	0.5	4.2	0.2	0.2	0.4	0.6	0.1	-0.2	1.1	-0.1	0.0	0.5	0.4	0.0	0.8	1.4	0.3	0.6	0.1	-0.1	0.1	0.5	0.1	0.5	2.0	1.4
Happiness	0.4	0.4	1.8	-0.8	-0.7	-0.6	-0.7	-0.7	1.2	0.2	-0.2	-0.3	-0.5	-0.6	-0.7	-0.7	0.4	-1.3	0.0	-0.6	-1.0	-0.4	-0.5	-0.5	-0.8	-0.2	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	2.1	-0.1	-0.4	-0.7	-0.2	-1.2	-1.1	0.2	-0.2	-0.5	-0.0	-1.5	-0.5	-0.6	0.1	-0.1	1.0	0.6	0.1	0.3	0.1	0.9	-0.1	0.3	1.4
Medication: Cholesterol lowering	0.4	0.7	2.1	-1.1	-0.5	-0.1	-1.3	-0.1	-0.7	-0.7	-0.8	-0.6	-1.3	-0.6	-0.3	-0.4	0.0	-1.0	-0.9	-0.5	-1.4	-1.0	-0.8	-0.8	-1.1	-0.6	0.4
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	2.0	0.9	0.7	0.5	0.6	0.7	-0.7	0.4	1.4	-1.0	1.0	0.1	0.3	0.3	0.1	0.1	0.3	0.8	0.8	0.4	0.8	0.7	0.8	0.5	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	2.2	-0.2	0.6	0.9	-0.7	0.3	0.4	0.6	0.2	0.3	-0.2	0.9	0.7	0.9	0.2	0.8	-1.2	1.2	-1.5	-0.9	0.2	-0.4	-0.0	-1.3	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	2.0	-0.6	-0.7	-0.9	-0.5	-0.6	0.3	-0.5	-0.6	0.0	-0.6	-0.7	-0.6	-0.9	-0.7	0.5	0.7	-1.0	-0.5	0.0	-0.6	0.1	-0.6	-1.4	-1.0
Shortness of breath walking on level ground	0.4	0.5	2.3	0.2	0.5	0.4	1.4	0.8	1.0	0.3	-0.3	0.8	0.5	1.5	-0.2	0.4	0.4	-0.0	-0.0	-0.1	0.8	0.2	-0.1	-0.4	0.3	1.4	-0.5
Mean time to correctly identify matches	0.4	0.8	4.3	-1.1	-0.6	-0.1	-0.2	0.4	0.1	-1.0	-1.0	-0.5	-1.1	1.0	-0.3	0.0	0.7	0.9	-0.6	-1.6	-0.6	-0.7	-0.9	-2.1	-0.9	0.6	-0.6
Whole body fat mass	0.4	1.5	7.2	-0.5	-1.0	-0.5	0.9	1.1	-1.6	0.2	-0.8	0.6	0.0	0.6	-0.6	-0.4	2.4	-0.3	0.9	-2.6	2.4	0.7	-0.7	-0.8	-0.3	2.7	-0.6
Comparative height size at age 10	0.4	2.0	9.0	0.8	-0.5	-0.9	1.7	-0.2	-0.9	-1.2	0.5	-0.5	0.9	-1.0	-0.9	-1.1	1.5	1.4	2.9	-1.5	2.5	3.0	-0.2	1.4	0.5	2.2	-0.1
Chest pain or discomfort	0.4	0.6	2.5	-0.1	-0.6	-0.5	0.8	0.8	-0.8	-1.2	-1.1	0.1	-0.3	0.7	-0.7	-0.8	0.9	0.1	0.6	-1.0	0.8	0.6	-0.7	-0.5	-0.3	0.3	-1.6
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.8	-0.1	0.7	1.0	-0.2	1.0	0.5	0.4	0.4	1.7	0.1	1.2	0.9	0.8	1.4	-0.0	-0.5	0.3	0.1	-0.6	-0.1	-0.5	0.1	0.8	0.3
Breast cancer (self-reported)	0.4	0.5	3.6	0.4	0.1	-0.1	-0.1	-0.4	-0.1	-0.5	0.5	0.5	0.2	-1.2	0.1	-0.2	0.4	-0.0	0.8	1.3	-0.8	-0.1	0.9	1.2	0.3	-0.4	1.9
Guilty feelings	0.4	0.7	1.9	-0.6	-1.1	-1.3	-0.6	-1.2	-0.7	-0.1	-0.4	-0.5	-0.6	-1.0	-0.9	-1.0	1.4	0.1	0.5	-0.9	-0.7	0.3	-0.8	-0.3	-0.8	-0.7	-1.3
Financial situation satisfaction	0.4	0.5	2.3	-0.7	-0.1	0.4	-0.6	-0.1	0.8	1.5	-0.2	0.2	-0.4	0.6	-0.0	0.5	0.7	-0.7	-0.4	-0.0	-1.5	-1.2	-0.6	-1.1	-0.6	0.4	-0.4
Supplements: Fish oil (including cod liver oil)	0.4	0.6	4.8	0.0	-0.2	-0.5	-0.3	-1.5	-0.7	1.2	0.2	-2.2	0.1	-1.0	-0.3	0.0	-0.3	-0.0	0.5	0.5	-0.0	0.4	-0.1	0.7	0.0	0.8	1.0
Medication: Bendroflumethiazide	0.4	0.6	1.9	1.0	0.5	0.2	0.9	0.3	0.2	-0.1	0.1	-0.0	1.2	0.0	0.8	0.3	0.9	-0.8	1.4	0.4	1.1	0.4	0.6	1.1	0.9	1.0	0.9
Leg fat percentage (left)	0.4	1.4	5.8	-1.5	-1.6	-1.0	-0.6	0.1	-1.6	-0.4	-1.5	-0.1	-1.1	-0.1	-1.3	-0.8	1.2	-1.5	-0.8	-2.4	0.9	-1.1	-1.3	-1.7	-1.2	1.0	-0.7
Number of operations (self-reported)	0.4	0.6	2.7	-0.7	-1.1	-1.0	-0.1	-0.5	-0.1	-0.8	-0.7	-0.0	-0.7	-0.9	-1.6	-1.2	0.8	0.5	-0.0	-1.3	0.1	0.3	-0.7	-0.5	-0.8	0.3	-0.7
Pain experienced in last month	0.4	0.7	3.5	0.6	0.5	0.0	0.1	-0.6	-0.2	-0.7	0.7	-1.7	0.6	-0.7	0.3	0.1	-1.9	-0.9	0.1	1.4	0.0	0.2	0.7	1.1	0.5	-0.1	1.3
Neuroticism (Nagel 2018)	0.3	0.7	3.4	-1.0	-0.8	-0.5	-1.1	-0.6	-0.4	0.2	-0.9	-0.5	-1.3	-0.5	-0.2	-0.3	0.5	-0.1	-0.5	-0.2	-1.9	-1.1	-0.7	-0.8	-1.0	-1.7	-0.9
Worry (Nagel 2018)	0.3	0.7	3.0	0.7	0.5	0.4	0.3	0.3	-0.9	1.1	0.6	-0.1	0.6	-0.1	1.0	0.6	1.5	0.6	1.0	1.7	-0.6	0.4	1.2	0.9	0.8	0.5	1.3
Alzheimer’s Disease (in father)	0.3	0.3	0.7	-0.5	-0.6	-0.7	-0.6	-0.6	0.0	-0.4	-0.5	-0.7	-0.5	-0.4	-0.8	-0.7	-0.1	-0.9	-0.1	-0.5	-0.1	-0.3	-0.6	-0.2	-0.6	-0.4	-0.8
Age at First Birth	0.3	0.5	2.7	-0.3	-0.9	-1.0	-0.4	-0.7	-0.8	-0.8	-0.4	-1.1	-0.2	-0.7	-0.7	-1.0	-0.2	-1.7	0.2	-0.3	0.2	0.3	-0.5	0.0	-0.3	-0.7	-0.9
Blood White Count	0.3	1.9	6.5	0.6	1.8	2.2	-0.3	1.1	-0.1	2.1	1.2	0.2	0.7	1.7	2.1	2.5	0.5	-0.0	-1.5	1.8	-1.4	-0.7	1.5	-0.4	1.1	0.6	1.3
Hand grip strength (left)	0.3	0.9	5.5	-0.6	-0.8	-0.8	-0.1	-1.0	-2.4	-1.6	-0.9	-0.8	-0.6	-0.3	-1.4	-1.0	0.6	0.2	0.2	-1.1	-0.1	0.2	-1.3	-0.6	-0.8	0.4	-0.6
Vitamin and mineral supplements	0.3	0.4	3.0	-0.4	-0.3	-0.5	-0.6	-0.9	0.4	-0.6	-0.3	-0.5	-0.8	-1.1	0.1	-0.4	-1.7	-0.0	-0.4	-0.3	-0.6	0.1	0.2	0.4	-0.4	-1.3	0.0
Severe depression (siblings)	0.3	0.3	2.4	-0.3	0.5	0.7	-0.8	-0.3	-0.2	0.2	-0.3	-0.1	-0.5	-0.3	0.1	0.5	-0.2	-0.3	-1.1	0.2	-1.5	-0.8	-0.2	0.0	-0.3	-0.4	1.1
Pack years adult smoking proportion	0.3	0.5	2.6	-1.0	-0.6	-0.2	0.0	0.4	0.0	0.4	-0.3	-0.4	-0.5	0.8	-1.2	-0.0	0.5	0.6	-1.6	-1.0	0.5	-0.2	-0.4	-1.4	-0.6	0.8	-0.4
Relative age voice broke	0.3	0.4	1.7	-0.4	-0.0	0.4	-0.2	1.3	0.3	0.7	-0.5	1.2	-0.5	1.0	0.2	0.4	-0.5	0.1	-1.0	-0.1	-0.8	-0.9	0.1	-1.2	-0.3	-0.7	-0.6
High blood pressure	0.3	0.8	3.3	0.1	-0.8	-1.1	0.8	-0.3	-1.2	0.2	-0.6	-1.7	0.2	-0.7	0.0	-1.0	0.6	-0.4	1.3	-0.5	1.4	1.2	0.3	0.6	0.0	1.8	0.5
Stomach or abdominal pain in last month	0.3	0.3	3.3	-0.3	-0.5	-0.3	0.1	0.2	0.7	-0.1	-0.4	-0.4	-0.2	0.3	-0.2	-0.3	0.7	1.0	0.1	-1.8	0.6	0.1	-0.2	-0.7	-0.2	0.4	-0.7
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	2.4	-0.3	-0.4	-0.4	-0.7	-0.7	0.1	-1.2	-0.5	-1.5	-0.2	-0.6	-0.2	-0.5	1.3	-0.5	-0.2	-0.6	-0.1	-0.4	-0.0	0.0	-0.4	-0.4	0.1
Sitting height	0.3	1.9	7.1	1.6	0.9	0.5	1.2	0.4	0.1	0.2	1.2	1.2	1.4	-0.2	1.0	0.3	1.9	2.2	2.6	0.1	1.4	2.7	0.7	2.2	1.3	1.4	0.2
Chronic bronchitis/emphysema (father)	0.3	0.4	1.8	-0.5	-0.1	0.0	-0.9	-0.5	0.8	0.1	-0.6	0.6	-0.5	-0.0	-0.3	-0.0	0.8	-1.3	-1.1	-0.7	-0.2	-0.9	-0.6	-0.6	-0.4	-0.8	-0.2
Arm fat percentage (right)	0.3	1.2	7.0	-0.7	-0.8	-0.2	0.5	1.3	-0.7	0.5	-0.9	0.9	-0.2	1.2	-0.2	-0.0	2.1	-0.5	0.1	-2.6	1.7	0.1	-0.7	-1.3	-0.4	2.1	-0.8
Falls in the last year	0.3	0.4	3.7	0.4	0.6	0.4	0.7	0.4	-1.1	-0.4	-0.9	-0.4	0.2	1.0	0.0	0.4	0.4	1.9	-0.3	0.0	0.4	0.8	-0.1	0.1	0.4	-0.2	-0.9
Hair/balding pattern: Pattern 3	0.3	0.5	2.4	0.7	0.3	0.3	0.5	0.1	-1.3	-0.2	0.4	-0.5	0.5	-0.4	0.7	0.3	0.1	-0.3	0.9	-0.2	0.4	0.8	0.2	0.7	0.5	1.6	1.4
Length of working week for main job	0.3	0.3	1.5	-0.1	-0.2	-0.3	0.2	-0.0	-0.3	0.1	-0.7	0.6	-0.1	0.2	-0.7	-0.2	1.2	-0.8	0.0	-0.9	0.7	0.5	0.0	-0.6	-0.2	1.1	0.4
Peak expiratory flow (PEF)	0.3	0.7	6.1	0.1	0.6	1.1	0.0	1.0	-0.6	1.0	0.4	0.6	0.1	1.3	0.7	0.9	2.5	-0.4	-0.3	0.9	-0.6	-0.2	-0.4	-0.8	0.1	0.7	-0.4
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	1.8	-0.3	0.2	0.3	-1.0	-0.9	0.3	1.2	-0.2	-0.2	-0.3	-0.1	0.5	0.5	0.2	0.8	-0.9	0.5	-1.2	-0.1	-0.4	-0.1	-0.2	-1.3	-0.6
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.4	1.0	0.8	0.6	0.7	0.4	1.0	0.7	1.1	1.0	1.2	1.0	0.4	0.5	0.2	0.8	0.2	0.4	0.7	0.6	0.3	0.4	0.9	0.2	-0.8
Eye problems/disorders: None of the above	0.3	0.4	2.1	0.3	-0.3	-0.6	0.5	-0.6	0.7	0.5	-0.1	-0.3	0.5	-0.2	-0.3	-0.1	0.4	0.3	0.6	-1.0	1.4	1.0	-0.6	0.2	0.2	1.2	-0.1
Emphysema/chronic bronchitis	0.3	0.3	1.5	-0.6	-0.3	-0.1	-0.2	-0.2	-0.6	0.6	-0.4	0.2	-0.3	0.2	-0.8	0.1	0.3	-0.9	-0.4	-0.8	-0.4	-0.4	-0.1	-0.7	-0.4	1.2	1.1
Migraine (self-reported)	0.3	0.4	1.7	0.4	0.2	0.3	0.5	0.2	0.7	1.0	-0.0	1.0	0.1	-0.2	0.3	0.3	0.6	-1.0	0.9	0.6	0.1	0.1	0.5	0.6	0.3	0.8	1.3
Heart disease (mother)	0.3	0.3	1.7	-0.1	0.2	0.3	0.6	1.2	-0.5	-0.1	-0.1	1.3	-0.0	0.9	0.5	0.1	-0.6	0.8	0.2	-0.2	0.7	0.5	-0.1	-0.3	0.1	0.3	-0.5
Leg fat mass (right)	0.3	1.2	6.5	-0.6	-1.0	-0.6	0.5	0.7	-1.6	0.2	-0.7	0.2	-0.2	0.1	-0.7	-0.4	2.1	-0.5	0.8	-2.4	1.9	0.6	-0.4	-0.7	-0.4	2.5	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	2.1	-0.5	-0.6	-0.5	-0.2	-0.8	-0.3	-1.0	-0.5	0.6	-0.3	-0.7	-0.8	-0.6	0.3	-1.4	0.4	-1.0	0.4	-0.3	0.1	-0.1	-0.4	-0.1	1.0
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	2.8	0.5	0.6	0.5	-0.0	0.2	0.4	-0.3	0.7	-0.4	0.3	0.4	-0.2	0.6	-1.7	0.6	-0.7	0.9	0.2	-0.4	0.4	0.1	0.4	-0.9	-0.7
Medication: Aspirin	0.3	0.4	1.0	-0.8	-0.6	-0.4	-0.4	-0.3	-0.2	0.3	-0.7	0.7	-1.0	-0.5	-0.9	-0.5	1.0	-0.6	-0.2	0.1	-0.3	-0.1	-1.0	-0.8	-0.7	-0.2	-0.5
Hypertension (Self-reported)	0.3	0.7	3.0	0.3	-0.6	-0.8	0.8	-0.1	-1.1	0.3	-0.3	-1.7	0.4	-0.5	0.3	-0.7	0.8	0.0	1.4	-0.2	1.4	1.2	0.5	0.7	0.3	1.7	0.5
Arm fat percentage (left)	0.3	1.2	6.9	-0.8	-1.1	-0.6	0.3	0.9	-0.8	0.5	-1.0	0.6	-0.3	0.8	-0.5	-0.4	2.2	-0.6	0.3	-2.6	1.7	0.2	-0.9	-1.3	-0.5	2.0	-1.0
Mineral and other dietary supplements	0.3	0.4	1.6	-0.6	-0.5	-0.3	0.0	0.7	0.6	-1.2	-0.6	0.9	-0.4	0.5	-0.2	-0.5	0.3	-0.2	-0.3	-1.3	0.1	-0.6	-0.5	-0.7	-0.5	-0.5	-1.0
Commuting to job workplace: Public transport	0.3	0.3	1.6	0.3	0.8	0.7	-0.2	-0.4	-0.3	0.2	0.3	-0.5	0.1	0.1	0.4	0.9	-0.3	0.7	-0.8	1.3	-0.9	0.3	0.2	0.6	0.3	-0.6	0.5
Medication: Atorvastatin	0.3	0.4	1.4	-0.0	0.6	0.9	0.1	0.7	-0.8	0.9	-0.1	-0.5	-0.0	0.7	0.9	0.7	0.8	-0.2	-0.5	1.2	-0.5	0.1	0.3	-0.5	0.1	0.7	0.7
Ever depressed for a whole week	0.3	0.4	2.5	-0.2	0.4	0.5	0.1	0.4	0.8	0.5	0.1	1.6	0.1	0.5	0.3	0.2	0.3	1.1	-0.1	0.6	-1.5	-0.4	-0.1	-0.0	-0.1	-0.8	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	2.3	-0.2	-0.7	-0.5	-0.0	0.3	-0.5	-0.9	0.0	-1.0	0.0	-0.1	-0.8	-0.7	0.1	0.1	0.2	-1.5	1.4	0.2	-0.2	-0.2	-0.2	-0.0	-0.3
Pack years of smoking	0.3	0.4	2.2	-0.8	-0.4	-0.0	0.2	0.7	0.4	0.1	0.2	-0.3	-0.2	0.9	-1.0	0.1	0.7	0.5	-1.5	-0.8	0.7	0.0	-0.1	-1.2	-0.3	1.1	-0.1
Leg fat mass (left)	0.3	1.4	8.5	-0.0	-0.5	-0.1	1.1	1.2	-1.3	0.4	-0.3	0.7	0.3	0.6	-0.1	0.0	2.6	-0.2	1.1	-2.0	2.3	0.8	-0.1	-0.3	0.2	2.9	-0.0
Alzheimer’s Disease (in mother)	0.2	0.2	1.3	-0.5	-0.2	-0.1	-0.4	-0.1	-1.2	0.1	-0.6	-0.1	-0.5	0.3	0.4	0.0	0.7	0.4	-0.4	-0.5	-0.1	0.1	-0.5	-0.5	-0.6	0.3	-0.2
Alzheimer’s Disease (including proxy)	0.2	0.3	2.0	-0.4	-0.4	-0.3	-0.5	-0.3	-1.3	-0.1	-0.6	-0.2	-0.4	-0.1	-0.0	-0.2	1.4	0.3	-0.1	-0.9	0.2	0.3	-0.6	-0.2	-0.5	0.4	-0.4
Neuroticism (2016)	0.2	0.2	2.0	-0.2	-0.2	0.2	-0.1	0.8	0.7	0.5	-0.0	-0.3	-0.4	-0.2	0.2	0.3	0.8	1.4	0.2	-0.1	-0.7	-0.1	0.2	0.1	-0.0	-0.5	-0.4
Blood Red Count	0.2	2.0	9.3	0.4	-1.4	-2.1	0.9	-1.4	-1.4	-0.3	0.2	-3.0	0.7	-1.3	-1.1	-1.7	-1.3	-0.5	1.7	-0.5	2.2	2.7	-0.6	1.0	0.3	1.0	-1.1
Cardiovascular Disease	0.2	0.7	4.0	0.2	-0.7	-0.9	0.9	-0.1	0.1	0.6	-0.3	-0.8	0.5	-0.4	0.1	-0.7	1.0	0.2	1.6	-0.7	1.7	1.4	-0.1	0.6	0.3	2.0	0.0
Lung FEV1/FVC ratio	0.2	1.1	4.5	-0.5	-0.1	0.7	-0.7	2.0	1.5	0.1	-0.3	1.0	-0.4	1.0	0.6	0.4	1.0	-0.1	-2.1	-0.9	-0.8	-1.8	-0.7	-1.4	-0.5	-1.1	-1.2
Neuroticism	0.2	0.4	2.2	-0.4	-0.3	0.1	-0.5	0.4	-0.4	1.1	-0.1	-0.1	-0.6	-0.1	0.1	0.3	1.5	0.5	-0.5	0.5	-1.2	-0.8	0.0	-0.4	-0.2	-0.9	-0.2
Sensitivity / hurt feelings	0.2	0.3	0.8	-0.5	0.0	0.3	-0.6	0.5	0.3	0.5	-0.3	0.7	-0.7	0.3	0.4	0.2	0.5	0.3	-0.9	0.4	-0.6	-0.8	-0.3	-0.6	-0.4	-0.9	-0.5
Diabetes (mother)	0.2	0.3	1.1	-0.5	-0.4	-0.2	0.4	0.5	-0.6	-1.0	-0.5	1.0	-0.4	-0.0	-0.3	-0.4	0.9	-0.3	0.1	-0.9	0.5	0.1	-0.3	-0.4	-0.3	0.3	-0.3
Taking other prescription medications	0.2	0.3	1.9	0.2	-0.1	-0.1	0.5	0.4	0.5	-0.3	0.1	0.5	0.2	-0.4	-0.2	-0.1	0.9	0.4	1.1	-0.1	0.8	1.0	0.4	0.2	0.1	1.4	0.7
Had other major operations	0.2	0.2	1.2	0.4	0.5	0.5	0.5	0.3	-0.4	0.7	0.6	-0.0	0.3	0.0	-0.0	0.5	-0.0	0.8	-0.1	1.1	-0.1	0.1	0.5	0.5	0.4	-0.1	0.3
Neuroticism score	0.2	0.4	3.5	-0.3	-0.0	0.3	-0.7	0.2	0.2	1.9	-0.2	-0.2	-0.5	-0.2	0.6	0.5	0.9	0.2	-0.6	0.8	-1.4	-0.6	0.4	-0.3	-0.1	-0.6	0.3
Medication: Lansoprazole	0.2	0.3	1.5	-0.3	-0.3	-0.4	-0.3	-0.6	-0.7	-0.6	-0.2	0.1	-0.1	-0.7	-0.1	-0.5	0.5	-1.2	-0.2	-0.1	1.1	0.0	-0.7	0.0	-0.2	0.6	0.1
Illnesses of mother	0.2	0.3	2.5	0.4	0.1	-0.1	0.1	-0.5	-0.2	1.6	0.5	-1.3	0.3	-0.4	-0.4	0.4	0.4	0.9	-0.2	0.4	-0.1	0.4	0.3	0.6	0.2	0.3	0.1
Standing height	0.2	2.3	8.8	0.5	-0.8	-1.2	1.6	-0.1	-1.2	-0.9	-0.1	-0.0	0.7	-0.3	-1.4	-1.5	1.3	2.0	3.0	-2.2	2.6	3.0	-1.1	0.8	0.1	2.1	-1.8
Medication: Blood pressure	0.2	0.4	2.2	-1.1	-0.7	-0.4	-0.5	-0.2	0.2	0.0	-1.5	-0.5	-1.2	-0.3	-0.1	-0.2	-0.1	-0.2	-0.4	-0.7	-0.9	-0.6	-0.5	-0.9	-0.9	-0.0	0.5
Illnesses of father: Heart disease	0.2	0.2	1.1	0.2	-0.2	-0.0	0.8	0.6	-0.2	0.9	-0.4	-0.1	0.0	-0.0	0.5	-0.0	-0.0	0.5	0.8	-0.0	0.5	0.6	-0.0	0.1	0.2	1.1	0.6
Medication: Aspirin	0.2	0.2	2.5	-0.1	-0.0	0.0	0.2	0.2	0.2	0.5	-0.1	1.0	-0.2	-0.2	-0.3	0.0	1.6	-0.5	0.4	0.7	0.5	0.4	-0.2	-0.1	0.0	0.5	0.1
Average weekly beer plus cider intake	0.2	0.3	1.5	-0.3	-0.8	-0.8	-0.0	-0.1	-0.1	-0.7	-0.7	-1.1	-0.2	-0.2	0.1	-0.8	-0.4	0.7	0.6	-0.6	1.2	0.2	-0.2	-0.5	-0.3	0.4	-0.4
Diastolic blood pressure, automated reading	0.2	0.5	1.8	-0.0	-0.9	-0.9	0.8	-0.1	0.0	-0.8	-1.0	-1.1	-0.1	-0.4	0.4	-0.8	-1.3	-0.2	1.0	-0.6	0.7	1.2	-0.2	0.1	-0.0	0.8	-0.3
Commuting to job workplace: Cycle	0.2	0.2	1.4	0.0	-0.2	-0.3	0.0	-0.4	0.0	0.0	-0.3	0.7	-0.1	0.1	-0.3	-0.1	1.2	-0.0	0.8	-0.4	0.1	0.1	-0.5	0.1	-0.1	-0.6	-1.1
Vascular/heart problems diagnosed by doctor	0.2	0.6	3.5	0.2	0.9	1.0	-0.7	-0.1	1.0	-0.1	0.7	0.8	0.1	0.4	0.1	1.0	-1.0	0.2	-1.1	0.7	-1.1	-1.1	0.1	-0.0	0.2	-1.9	-0.3
Blood Eosinophil Count	0.1	1.1	3.4	1.0	0.4	0.0	1.3	0.0	-1.0	0.8	0.1	-1.5	1.0	0.1	0.7	0.3	1.0	1.2	1.8	-0.6	1.7	1.8	0.5	1.1	1.0	1.5	0.5
Hair Pigment	0.1	1.5	5.7	0.0	-1.1	-1.4	1.1	0.5	0.8	-0.8	-0.1	-1.0	0.1	-0.6	-1.0	-1.6	-0.1	2.2	1.8	-2.3	1.7	1.7	-0.6	0.4	-0.2	-0.4	-2.4
High blood pressure (mother)	0.1	0.2	0.6	-0.2	-0.4	-0.5	-0.1	-0.7	0.5	-0.3	-0.5	0.2	-0.2	-0.6	0.4	-0.6	-0.6	0.3	0.8	0.1	0.2	0.6	-0.3	0.2	-0.2	0.3	0.1
Illnesses of siblings	0.1	0.2	2.3	0.1	0.3	0.1	-0.3	-0.4	-0.0	0.2	0.5	-0.5	0.1	0.0	-0.4	0.2	0.5	1.5	-0.2	-0.1	-0.2	0.1	0.1	0.3	-0.0	0.8	0.4
Tense / ‘highly strung’	0.1	0.2	1.6	-0.4	-0.2	0.1	-0.3	-0.0	0.7	0.2	-0.8	-0.1	-0.4	0.1	0.3	0.5	0.8	-0.2	-0.6	0.5	-1.3	-0.2	0.4	-0.7	-0.1	-0.0	0.6
Exposure to tobacco smoke outside home	0.1	0.2	0.8	-0.3	-0.3	-0.1	0.5	0.5	-0.1	-0.2	-0.5	0.8	-0.2	0.6	-0.3	0.1	-0.2	0.4	-0.3	-0.6	0.5	0.2	-0.4	-0.9	-0.2	0.3	-0.5
Alcohol intake frequency.	0.1	0.3	1.7	-0.2	0.2	0.7	-0.4	1.0	0.5	0.6	0.1	0.1	-0.3	0.4	0.2	0.6	0.6	-1.0	-1.3	0.2	-0.6	-0.9	0.5	-0.5	-0.1	-0.4	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Tanning	0.0	0.2	1.1	-0.1	0.0	0.1	0.2	0.0	-0.9	-0.4	0.1	-0.7	-0.0	0.1	-0.1	0.1	-0.0	1.0	-0.6	-0.3	-0.3	-0.0	0.1	0.0	-0.2	1.1	0.6

Hub : Genes

CTNNAL1

Models

Trait associations