Best TWAS P=2.4e-10 · Best GWAS P=1.67e-11 conditioned to 4.53e-07
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | OBP2B | 0.03 | 0.02 | blup | 33 | 0.02 | 5.5e-05 | 3.8 | -5.9 | 4.8e-09 | -0.77 | 0.01 | 0.98 | FALSE |
2 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | ABO | 0.23 | 0.07 | blup | 44 | 0.12 | 4.3e-04 | -1.7 | -6.3 | 2.4e-10 | -0.30 | 0.02 | 0.05 | TRUE |